Research Topics
| Nancy J MinshewSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Detail Information
Publications
Underdevelopment of the postural control system in autismNancy J Minshew
Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara St, Webster Hall, Suite 300, Pittsburgh, PA 15213, USA
Neurology 63:2056-61. 2004..To determine if abnormalities exist in postural control in autism and if they are related to age...
The new neurobiology of autism: cortex, connectivity, and neuronal organizationNancy J Minshew
Webster Hall, Suite 300, 3811 O Hara St, Pittsburgh, PA 15213, USA
Arch Neurol 64:945-50. 2007..The multiorgan system involvement and diversity of central nervous system findings suggest an epigenetic mechanism...- Sensory sensitivities and performance on sensory perceptual tasks in high-functioning individuals with autismNancy J Minshew
Departments of Psychiatry and Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
J Autism Dev Disord 38:1485-98. 2008..These findings support the common occurrence of sensory symptoms in high functioning autism based on first person report, and the presence of neurological abnormalities in higher cortical sensory perception... - The nature of brain dysfunction in autism: functional brain imaging studiesNancy J Minshew
University of Pittsburgh School of Medicine, Webster Hall, Suite 300, 3811 O Hara Street, USA
Curr Opin Neurol 23:124-30. 2010.... - Atypical frontal-posterior synchronization of Theory of Mind regions in autism during mental state attributionRajesh K Kana
Carnegie Mellon University, Pittsburgh, PA, USA
Soc Neurosci 4:135-52. 2009..The results together provide new evidence for the biological basis of atypical processing of ToM in autism, implicating the underconnectivity between frontal regions and more posterior areas... - The profile of memory function in children with autismDiane L Williams
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Neuropsychology 20:21-9. 2006..A principal components analysis indicated that the factor structure of the subtests differed substantially between the children with autism and controls, suggesting differing organizations of memory ability... - Distinctive neural processes during learning in autismSarah E Schipul
Department of Psychology, Center for Cognitive Brain Imaging, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Cereb Cortex 22:937-50. 2012..The findings suggest that cortical underconnectivity in autism may constrain the ability of the brain to rapidly adapt during learning... - The neural basis of deictic shifting in linguistic perspective-taking in high-functioning autismAkiko Mizuno
Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213 3890, USA
Brain 134:2422-35. 2011.... - Cortical underconnectivity coupled with preserved visuospatial cognition in autism: Evidence from an fMRI study of an embedded figures taskSaudamini Roy Damarla
Center for Cognitive Brain Imaging, Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennysylvania 15213, USA
Autism Res 3:273-9. 2010..Thus, even in the visuospatial domain, where preserved performance among people with autism is observed, the neuroimaging signatures of cortical underconnectivity persist... - Neuropsychologic functioning in children with autism: further evidence for disordered complex information-processingDiane L Williams
University of Pittsburgh School of Medicine, USA
Child Neuropsychol 12:279-98. 2006..Children as compared to adults with autism exhibited more prominent sensory-perceptual symptoms and less pronounced reasoning deficits reflecting brain maturation... - Inhibitory control in high-functioning autism: decreased activation and underconnectivity in inhibition networksRajesh K Kana
Center for Cognitive Brain Imaging, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
Biol Psychiatry 62:198-206. 2007..There has been only one published functional magnetic resonance imaging (fMRI) study so far on inhibition in autism, which found greater activation in participants with autism than control participants... - Oculomotor studies of cerebellar function in autismCaralynn V Nowinski
Department of Psychiatry, MC 913, University of Illinois at Chicago, 912 S. Wood St, Suite 235, Chicago, IL 60612-7327, USA
Psychiatry Res 137:11-9. 2005..The atypical metrics of intrusive saccades that were observed may be attributable to faulty functional connectivity in cortico-cerebellar networks... - Brief report: abnormal association between the thalamus and brain size in Asperger's disorderAntonio Y Hardan
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
J Autism Dev Disord 38:390-4. 2008.... - Sentence comprehension in autism: thinking in pictures with decreased functional connectivityRajesh K Kana
Center for Cognitive Brain Imaging, Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Brain 129:2484-93. 2006.... - Category formation in autism: can individuals with autism form categories and prototypes of dot patterns?Holly Zajac Gastgeb
Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA
J Autism Dev Disord 42:1694-704. 2012..Results are consistent with previous studies that have found deficits in prototype formation and extend these deficits to dot patterns... - A lack of left visual field bias when individuals with autism process facesEva M Dundas
University of Pittsburgh, Pittsburgh, PA, USA
J Autism Dev Disord 42:1104-11. 2012..Eye-tracking technology was used to show that individuals with autism were not spontaneously biased to facial information in the LVF, in contrast to a control group, while discriminating facial gender... - Can individuals with autism abstract prototypes of natural faces?Holly Zajac Gastgeb
Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA
J Autism Dev Disord 41:1609-18. 2011..Results are consistent with previous studies that have found a deficit in prototype formation and extend these deficits to natural faces... - Memory awareness for faces in individuals with autismDesirée A Wilkinson
Department of Psychology, University of Pittsburgh, 210 South Bouquet Street, Pittsburgh, PA 15260, USA
J Autism Dev Disord 40:1371-7. 2010..Subtle impairments in memory awareness for faces were also evident in adults with autism. Results indicate that broader metacognitive deficits may exist in individuals with autism, possibly contributing to other known impairments... - The structure of intelligence in children and adults with high functioning autismGerald Goldstein
VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania 15206, USA
Neuropsychology 22:301-12. 2008..Findings suggest similar organization of cognitive abilities in HFA, but with the possibility of underconnectivity or reduced communication among brain regions in autism... - Maturation of executive function in autismBeatriz Luna
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Biol Psychiatry 61:474-81. 2007..Executive dysfunction has been reported at different ages in autism. It is not clear however, when this impairment emerges or how its expression is affected by development... - Is he being bad? Social and language brain networks during social judgment in children with autismElizabeth J Carter
Robotics Institute, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA
PLoS ONE 7:e47241. 2012..The fMRI results indicate that AD children may not automatically use language to encode their social understanding, making expression and generalization of this knowledge more difficult... - Dorsolateral prefrontal cortex magnetic resonance imaging measurements and cognitive performance in autismJessica Griebling
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
J Child Neurol 25:856-63. 2010..The absence of correlations suggests that executive dysfunction is not the result of focal brain alterations but, rather, is the result of a distributed neural network dysfunction... - Corpus callosum volume and neurocognition in autismChristopher J Keary
Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
J Autism Dev Disord 39:834-41. 2009..These findings provide further evidence for anatomical alterations in the corpus callosum in autism, but warrant additional studies examining the relationship of this structure and specific measures of interhemispheric connectivity... 
Autonomy of lower-level perception from global processing in autism: evidence from brain activation and functional connectivityYanni Liu
Center for Cognitive Brain Imaging, Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, United States
Neuropsychologia 49:2105-11. 2011..The results from this study provide the first direct neural evidence of reduced global-to-local interference in autism...- Functional connectivity in an fMRI working memory task in high-functioning autismHideya Koshino
Center for Cognitive Brain Imaging, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Neuroimage 24:810-21. 2005..The temporal profile of the activity in the prefrontal regions was more correlated with the left parietal regions for the control group, whereas it was more correlated with the right parietal regions for the autism group... - Verbal and spatial working memory in autismDiane L Williams
School of Medicine, University of Pittsburgh, PA 15213, USA
J Autism Dev Disord 35:747-56. 2005.... - Functional and anatomical cortical underconnectivity in autism: evidence from an FMRI study of an executive function task and corpus callosum morphometryMarcel Adam Just
Center for Cognitive Brain Imaging, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Cereb Cortex 17:951-61. 2007..The results add support to a new theory of cortical underconnectivity in autism, which posits a deficit in integration of information at the neural and cognitive levels... - Gender discrimination of eyes and mouths by individuals with autismCatherine A Best
Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
Autism Res 3:88-93. 2010..However, results indicated that compared to adults without autism, adults with autism were significantly worse at discriminating gender from eyes... - Unreliable evoked responses in autismILAN DINSTEIN
Department of Psychology, Baker Hall, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Neuron 75:981-91. 2012..The results motivate a critical expansion of autism research to determine whether (and how) basic neural processing properties such as reliability, plasticity, and adaptation/habituation are altered in autism... - The development of emotion recognition in individuals with autismKeiran M Rump
University of Pittsburgh, Pittsburgh, PA 15260, USA
Child Dev 80:1434-47. 2009..Results are discussed with respect to underlying cognitive processes that may be affecting the development of emotion recognition in individuals with autism... - Abnormal brain size effect on the thalamus in autismAntonio Y Hardan
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Psychiatry Res 147:145-51. 2006.... - An MRI study of minor physical anomalies in autismAntonio Y Hardan
Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213, USA
J Autism Dev Disord 36:607-11. 2006..Hypotelorism is a MPA that may be present in a subgroup of individuals with autism. Additional research is warranted using large sample sizes with a wide range of intellectual functioning... - Variability in adaptive behavior in autism: evidence for the importance of family historyCarla A Mazefsky
Departments of Pediatrics and Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
J Abnorm Child Psychol 36:591-9. 2008..This study provides initial evidence of the importance of family history to adaptive behavior in autism and has implications for genetics and treatment... - Prototype formation in autism: can individuals with autism abstract facial prototypes?Holly Zajac Gastgeb
Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Autism Res 2:279-84. 2009..These results provide further evidence that individuals with autism have difficulty abstracting subtle spatial information that is necessary not only for the formation of a mean prototype, but also for categorizing faces and objects... - Volumetric alterations of the orbitofrontal cortex in autismRagy R Girgis
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York State Psychiatric Institute, New York, NY, USA
Prog Neuropsychopharmacol Biol Psychiatry 31:41-5. 2007..These findings support the role of OFC in autism and warrant further investigations of this structure using structural and functional methodologies... - Multivariate searchlight classification of structural magnetic resonance imaging in children and adolescents with autismLucina Q Uddin
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Biol Psychiatry 70:833-41. 2011..Characterization of brain structural differences in children with ASD is critical for development of biomarkers that may eventually be used to improve diagnosis and monitor response to treatment... - The application of short forms of the Wechsler Intelligence scales in adults and children with high functioning autismNancy J Minshew
University of Pittsburgh School of Medicine, Pittsburgh, USA
J Autism Dev Disord 35:45-52. 2005..8-.9 range. It was concluded that short forms may be used with good predictive accuracy in individuals with high functioning autism, even when the subtest profile is atypical... - The modality shift experiment in adults and children with high functioning autismDiane L Williams
Department of Speech Language Pathology, Duquesne University, Pittsburgh, PA, USA
J Autism Dev Disord 43:794-806. 2013..These results suggest a lag in maturational development in autism in basic information processing mechanisms... - ASD, a psychiatric disorder, or both? Psychiatric diagnoses in adolescents with high-functioning ASDCarla A Mazefsky
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
J Clin Child Adolesc Psychol 41:516-23. 2012..Results emphasize the importance of increasing awareness of the manifestations of high-functioning autism in order to improve accuracy of diagnosis and appropriateness of interventions... - Increased frontal cortical folding in autism: a preliminary MRI studyAntonio Y Hardan
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Psychiatry Res 131:263-8. 2004..These preliminary findings suggest that the gyrification patterns in autism may be abnormal, which could be related to the various cortical anomalies observed in this disorder... - Understanding autism and related disorders: what has imaging taught us?Diane L Williams
Department of Speech Language Pathology, Rangos School of Health Sciences, Fisher Hall 412, Duquesne University, 600 Forbes Avenue, Pittsburgh, PA 15282, USA
Neuroimaging Clin N Am 17:495-509, ix. 2007.... - Cortical activation and synchronization during sentence comprehension in high-functioning autism: evidence of underconnectivityMarcel Adam Just
Carnegie Mellon University, Center for Cognitive Brain Imaging, Department of Psychology, Pittsburgh, PA 15213, USA
Brain 127:1811-21. 2004..The article presents a theoretical account of the findings, related to neurobiological foundations of underconnectivity in autism... - Impaired memory for faces and social scenes in autism: clinical implications of memory dysfunctionDiane L Williams
University of Pittsburgh School of Medicine, Webster Hall Suite 300, 3811 O'Hara Street, Pittsburgh, PA 15213, USA
Arch Clin Neuropsychol 20:1-15. 2005..Most importantly, the deficits in memory for faces and common social scenes, complex visual/spatial stimuli, demonstrate the contribution of memory dysfunction in autism to deficits in real life function... - A systematic review of psychosocial interventions for adults with autism spectrum disordersLauren Bishop-Fitzpatrick
School of Social Work, University of Pittsburgh, 2117 Cathedral of Learning, 4200 Fifth Ave, Pittsburgh, PA 15260, USA
J Autism Dev Disord 43:687-94. 2013..14-3.59, although the quantity and quality of studies is limited. There is substantial need for the rigorous development and evaluation of psychosocial treatments for adults with ASD... - Pursuit eye movement deficits in autismYukari Takarae
University of Illinois at Chicago, Chicago, Illinois and 2 University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Brain 127:2584-94. 2004.... - Eye movements in neurodevelopmental disordersJohn A Sweeney
Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois 60612 7327, USA
Curr Opin Neurol 17:37-42. 2004..It thus provides a promising methodology for characterizing and documenting maturational abnormalities in brain systems associated with neurodevelopmental disorders... - Motor performance and anatomic magnetic resonance imaging (MRI) of the basal ganglia in autismAntonio Y Hardan
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
J Child Neurol 18:317-24. 2003.... - Offering to share: how to put heads together in autism neuroimagingMatthew K Belmonte
Department of Human Development, Cornell University, Martha Van Rensselaer Hall, Ithaca, NY 14853 4401, USA
J Autism Dev Disord 38:2-13. 2008..A theme in these requirements is the need to preserve creative approaches and risk-taking within individual laboratories at the same time as common standards are provided for these laboratories to build on... - fMRI investigation of working memory for faces in autism: visual coding and underconnectivity with frontal areasHideya Koshino
Department of Psychology, California State University, San Bernardino, CA 92407, USA
Cereb Cortex 18:289-300. 2008.... - An MRI and proton spectroscopy study of the thalamus in children with autismAntonio Y Hardan
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA
Psychiatry Res 163:97-105. 2008..Further investigations of this structure are warranted, since it plays an important role in information processing as part of the cortico-thalamo-cortical pathways... - Do individuals with autism process categories differently? The effect of typicality and developmentHolly Zajac Gastgeb
University of Pittsburgh, 210 S Bouquet St Pittsburgh, PA 15260, USA
Child Dev 77:1717-29. 2006..Parallels are also drawn to the results of previous studies on face processing in individuals with autism... - Atypical involvement of frontostriatal systems during sensorimotor control in autismYukari Takarae
Department of Psychiatry MC 913, University of Illinois at Chicago, 912 S Wood St, Suite 235, Chicago, IL 60612 7327, USA
Psychiatry Res 156:117-27. 2007..These findings document that neurodevelopmental disturbances in autism affect widely distributed brain systems beyond those mediating language and social cognition... - An MRI study of increased cortical thickness in autismAntonio Y Hardan
Stanford University, Department of Psychiatry and Behavioral Sciences, 401 Quarry Rd, Stanford, CA 94305, USA
Am J Psychiatry 163:1290-2. 2006..The purpose of this study was to examine cortical thickness in autism in light of the postmortem evidence of cortical abnormalities of the disorder... - Spatial working memory deficits in autismShelly D Steele
Department of Psychology, University of Illinois at Chicago, Chicago, IL 60612 7327, USA
J Autism Dev Disord 37:605-12. 2007..Overall, these results demonstrate reduced spatial working memory abilities in autism, and extend previous findings by demonstrating that these deficits are significant when tasks impose heavier demands on working memory... - Abnormal brain lateralization in high-functioning autismPaul R Escalante-Mead
University of Illinois at Chicago, Chicago, IL 60612, USA
J Autism Dev Disord 33:539-43. 2003..The data indicated maturational disturbances in establishing lateral preference rather than increased rates of left handedness. Atypical establishment of cerebral dominance may be one cause of disordered language development in autism... - What is currently known about the neurobiology of autism and if the valuable resource of family time should be invested in these studiesNancy J Minshew
J Autism Dev Disord 34:737-8. 2004 - Magnetic resonance imaging study of the orbitofrontal cortex in autismAntonio Y Hardan
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305, USA
J Child Neurol 21:866-71. 2006..The present study suggests the absence of global volumetric abnormalities in the orbitofrontal cortex in autism and indicates that the functional disturbances in this structure might not be related to anatomic alterations... - Abstract reasoning in autism: a dissociation between concept formation and concept identificationNancy J Minshew
Department of Neurology, Rambam Medical Center and University of Haifa, Israel
Neuropsychology 16:327-34. 2002..Stepwise discriminant function analyses revealed that 2 tests of concept formation correctly classified 78.4% of cases, whereas concept identification tasks did not pass the tolerance test...