Research Topics
| MICHAEL MINNICKSummaryAffiliation: University of Montana Country: USA Publications
Research Grants
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Detail Information
Publications
Developmental biology of Coxiella burnetiiMichael F Minnick
Division of Biological Sciences, The University of Montana, Missoula, MT 59812, USA
Adv Exp Med Biol 984:231-48. 2012....- Genetics of Coxiella burnetii: on the path of specializationMichael F Minnick
Division of Biological Sciences, The University of Montana, Missoula, MT 59812, USA
Future Microbiol 6:1297-314. 2011..Understanding why these genetic elements are maintained may help us better understand the biology of this fascinating pathogen... 
Pentamidine inhibits Coxiella burnetii growth and 23S rRNA intron splicing in vitroMichael F Minnick
Division of Biological Sciences, The University of Montana, Missoula, MT 59812, USA
Int J Antimicrob Agents 36:380-2. 2010..burnetii. To our knowledge, this is the first report describing antibacterial activity for this antifungal/antiprotozoal agent...- Pestilence, persistence and pathogenicity: infection strategies of BartonellaMichael F Minnick
The University of Montana, Division of Biological Sciences, Missoula, MT 59812, USA
Future Microbiol 4:743-58. 2009.... - gyrA mutations in ciprofloxacin-resistant Bartonella bacilliformis strains obtained in vitroMichael F Minnick
Division of Biological Sciences, The University of Montana, Missoula, Montana 59812, USA
Antimicrob Agents Chemother 47:383-6. 2003..This is the first report of a mutation at an Asp-90 homologue, which corresponds to Asp-82 in E. coli GyrA... - Mitogenic effect of Bartonella bacilliformis on human vascular endothelial cells and involvement of GroELMichael F Minnick
Division of Biological Sciences, The University of Montana, Missoula, Montana 59812 4824, USA
Infect Immun 71:6933-42. 2003..Data also show that GroEL is located in the soluble and insoluble fractions (including inner and outer membranes) of the cell and is actively secreted by B. bacilliformis... - Function, regulation, and transcriptional organization of the hemin utilization locus of Bartonella quintanaNermi L Parrow
Division of Biological Sciences, The University of Montana, 32 Campus Drive, Missoula, MT 59812, USA
Infect Immun 77:307-16. 2009..Examination of the promoter regions of hutA, tonB, and hemS reveals consensus sequence promoters that encompass an H-box element previously shown to interact with B. quintana Irr... - Characterization and expression analysis of the groESL operon of Bartonella bacilliformisJulie A Callison
Division of Biological Sciences, The University of Montana, Missoula, MT, 59812 4824, USA
Gene 359:53-62. 2005..Functional expression and complementation of temperature-sensitive Escherichia coli groES or groEL mutants with the cloned operon allowed them to grow at otherwise restrictive temperatures... - II. Correlations between secondary structure stability and mutation frequency during somatic hypermutationBarbara E Wright
Division of Biological Sciences, The University of Montana, Missoula, MT 59812, USA
Mol Immunol 45:3600-8. 2008..These circumstances simplify the complexities of coordinating mutagenesis by confining this process to each mutable site successively, as they form in response to increasing levels of transcription during affinity maturation... - Five-member gene family of Bartonella quintanaMichael F Minnick
Division of Biological Sciences, The University of Montana, Missoula 59812, USA
Infect Immun 71:814-21. 2003.... 
Differential expression of the invasion-associated locus B (ialB) gene of Bartonella bacilliformis in response to environmental cuesSherry A Coleman
Division of Biological Sciences, The University of Montana, Missoula, MT 59812-4824, USA
Microb Pathog 34:179-86. 2003..Finally, we compared the survival of wild-type and ialB mutant B. bacilliformis and found no difference in the viability of these two strains, demonstrating that IalB does not aid bacterial survival under these conditions...- Transcriptional regulation of the heme binding protein gene family of Bartonella quintana is accomplished by a novel promoter element and iron response regulatorJames M Battisti
Division of Biological Sciences, The University of Montana, Missoula, MT 59812, USA
Infect Immun 75:4373-85. 2007.... - I. VH gene transcription creates stabilized secondary structures for coordinated mutagenesis during somatic hypermutationBarbara E Wright
Division of Biological Sciences, The University of Montana, Missoula, MT 59812, USA
Mol Immunol 45:3589-99. 2008..Such a complex of secondary structures may be the source of ssDNA for enzyme-based diversification, which ultimately results in high affinity antibodies... - Bartonella bacilliformis GroEL: effect on growth of human vascular endothelial cells in infected coculturesLaura S Smitherman
Division of Biological Sciences, University of Montana, Missoula, MT 59812 4824, USA
Ann N Y Acad Sci 1063:286-98. 2005..These data suggest another strategy whereby Bartonella may regulate host cell growth... - A DNA-binding peroxiredoxin of Coxiella burnetii is involved in countering oxidative stress during exponential-phase growthLinda D Hicks
Division of Biological Sciences, The University of Montana, Missoula, MT 59812, USA
J Bacteriol 192:2077-84. 2010..Taken as a whole, the results show that Coxiella BCP binds DNA and likely serves to detoxify endogenous hydroperoxide byproducts of Coxiella's metabolism during intracellular replication... - Toxic introns and parasitic intein in Coxiella burnetii: legacies of a promiscuous pastRahul Raghavan
Division of Biological Sciences, The University of Montana, Missoula, MT 59812, USA
J Bacteriol 190:5934-43. 2008.... - The unusual 23S rRNA gene of Coxiella burnetii: two self-splicing group I introns flank a 34-base-pair exon, and one element lacks the canonical omegaGRahul Raghavan
Division of Biological Sciences, The University of Montana, Missoula, MT 59812, USA
J Bacteriol 189:6572-9. 2007..burnetii's 23S rRNA gene is very unusual for an obligate intracellular bacterium and suggests a recent shift to its current lifestyle from a previous niche with greater opportunities for lateral gene transfer... - Environmental signals generate a differential and coordinated expression of the heme receptor gene family of Bartonella quintanaJames M Battisti
Division of Biological Sciences, The University of Montana, Missoula, MT 59812, USA
Infect Immun 74:3251-61. 2006..Finally, an hbpA promoter-lacZ reporter construct in B. quintana demonstrates that a transcriptional regulator(s) is controlling the expression of hbpA through a cis-acting regulatory element located in the hbpA promoter region... - Ribozyme stability, exon skipping, and a potential role for RNA helicase in group I intron splicing by Coxiella burnetiiLinda D Hicks
Division of Biological Sciences, The University of Montana, Missoula, MT 59812, USA
J Bacteriol 193:5292-9. 2011.... - Laboratory maintenance of Bartonella quintanaJames M Battisti
Division of Biological Sciences, The University of Montana, Missoula, Montana, USA
Curr Protoc Microbiol . 2008..quintana and can be applied to cultivation and preservation of all Bartonella. Detailed recipes for preparation of three types of semisolid media are also included... - Proteomic and immunoblot analyses of Bartonella quintana total membrane proteins identify antigens recognized by sera from infected patientsJenni K Boonjakuakul
Division of Infectious Diseases, 521 Parnassus Ave, Room C 443, University of California at San Francisco, San Francisco, CA 94143 0654, USA
Infect Immun 75:2548-61. 2007....
Research Grants
- Bartonella Inhibitory Factor for Endothelial Cell GrowthMICHAEL MINNICK; Fiscal Year: 2002..abstract_text> ..
- Hemin Receptor Gene Family of Bartonella quintanaMICHAEL MINNICK; Fiscal Year: 2003..Further, since Bartonella Hbp's are possibly members of an outer membrane protein family from several Gram-negative bacteria, data generated from this study will undoubtedly be of broad importance to bacterial pathogenesis. ..
- Hemin Receptor Gene Family of Bartonella quintanaMICHAEL MINNICK; Fiscal Year: 2006..abstract_text> ..