Jonathan Mink

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Quantitative telemedicine ratings in Batten disease: implications for rare disease research
    J Cialone
    University of Rochester, Rochester, NY, USA
    Neurology 77:1808-11. 2011
  2. ncbi request reprint New treatments for tic disorders
    Mohammad M Qasaymeh
    Child Neurology, Box 631, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Curr Treat Options Neurol 8:465-73. 2006
  3. ncbi request reprint Paroxysmal dyskinesias
    Jonathan W Mink
    Department of Neurology, University of Rochester, Rochester, New York 14642, USA
    Curr Opin Pediatr 19:652-6. 2007
  4. ncbi request reprint Patient selection and assessment recommendations for deep brain stimulation in Tourette syndrome
    Jonathan W Mink
    Department of Neurology, University of Rochester, Rochester, New York, USA
    Mov Disord 21:1831-8. 2006
  5. ncbi request reprint Clinical review of DBS for Tourette Syndrome
    Jonathan W Mink
    Department of Neurology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave, Box 631, Rochester, NY 14642, USA
    Front Biosci (Elite Ed) 1:72-6. 2009
  6. ncbi request reprint The Basal Ganglia and involuntary movements: impaired inhibition of competing motor patterns
    Jonathan W Mink
    Departments of Neurology, Neurobiology, and Anatomy, and Pediatrics, University of Rochester School of Medicine, Rochester, NY 14642, USA
    Arch Neurol 60:1365-8. 2003
  7. ncbi request reprint Progressive myoclonus in a child with a deep cerebellar mass
    Jonathan W Mink
    University of Rochester School of Medicine and Golisano Children s Hospital at Strong, Rochester, NY, USA
    Neurology 61:829-31. 2003
  8. ncbi request reprint Novel CLN3 mutation predicted to cause complete loss of protein function does not modify the classical JNCL phenotype
    Jennifer M Kwon
    Department of Neurology, 601 Elmwood Avenue, Box 631, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurosci Lett 387:111-4. 2005
  9. pmc Genotype does not predict severity of behavioural phenotype in juvenile neuronal ceroid lipofuscinosis (Batten disease)
    Heather R Adams
    Division of Child Neurology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Dev Med Child Neurol 52:637-43. 2010
  10. pmc Neuropsychological symptoms of juvenile-onset batten disease: experiences from 2 studies
    Heather R Adams
    University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    J Child Neurol 22:621-7. 2007

Research Grants

  1. PATHOPHYSIOLOGY OF DYSTONIA AND PARKINSONISM
    Jonathan W Mink; Fiscal Year: 2010
  2. PATHOPHYSIOLOGY OF DYSTONIA AND PARKINSONISM
    Jonathan Mink; Fiscal Year: 2009
  3. Clinical and Neuropsychological Investigations in Batten Disease
    Jonathan Mink; Fiscal Year: 2007
  4. PATHOPHYSIOLOGY OF DYSTONIA AND PARKINSONISM
    Jonathan Mink; Fiscal Year: 2007
  5. PATHOPHYSIOLOGY OF DYSTONIA AND PARKINSONISM
    Jonathan Mink; Fiscal Year: 2003
  6. PATHOPHYSIOLOGY OF CHOREA
    Jonathan Mink; Fiscal Year: 2002
  7. Clinical and Neuropsychological Investigations in Batten Disease
    Jonathan W Mink; Fiscal Year: 2010

Collaborators

Detail Information

Publications29

  1. pmc Quantitative telemedicine ratings in Batten disease: implications for rare disease research
    J Cialone
    University of Rochester, Rochester, NY, USA
    Neurology 77:1808-11. 2011
    ..To determine if remote administration of the Unified Batten Disease Rating Scale (UBDRS) Physical Impairment subscale by telemedicine is reliable and feasible across a broad range of disease severity...
  2. ncbi request reprint New treatments for tic disorders
    Mohammad M Qasaymeh
    Child Neurology, Box 631, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Curr Treat Options Neurol 8:465-73. 2006
    ..Start with 0.01 mg/kg/dose once a day; dosage may be increased by 0.02 mg/kg/day at weekly intervals, up to 0.06 mg/kg/dose once a day. Ziprasidone and olanzapine are reasonable alternatives...
  3. ncbi request reprint Paroxysmal dyskinesias
    Jonathan W Mink
    Department of Neurology, University of Rochester, Rochester, New York 14642, USA
    Curr Opin Pediatr 19:652-6. 2007
    ..Substantial progress has been made recently in understanding characteristic features of the paroxysmal dyskinesias and underlying genetic causes. This review summarizes the most important findings and discusses their implications...
  4. ncbi request reprint Patient selection and assessment recommendations for deep brain stimulation in Tourette syndrome
    Jonathan W Mink
    Department of Neurology, University of Rochester, Rochester, New York, USA
    Mov Disord 21:1831-8. 2006
    ....
  5. ncbi request reprint Clinical review of DBS for Tourette Syndrome
    Jonathan W Mink
    Department of Neurology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave, Box 631, Rochester, NY 14642, USA
    Front Biosci (Elite Ed) 1:72-6. 2009
    ..Accumulating data have been sufficiently promising to justify further study. Yet, many questions remain. Systematic, controlled, collaborative studies are required to answer the many questions that remain...
  6. ncbi request reprint The Basal Ganglia and involuntary movements: impaired inhibition of competing motor patterns
    Jonathan W Mink
    Departments of Neurology, Neurobiology, and Anatomy, and Pediatrics, University of Rochester School of Medicine, Rochester, NY 14642, USA
    Arch Neurol 60:1365-8. 2003
    ..A new model is presented here, building on existing models and data to encompass hypotheses of the fundamental pathophysiologic mechanisms underlying chorea, dystonia, and tics...
  7. ncbi request reprint Progressive myoclonus in a child with a deep cerebellar mass
    Jonathan W Mink
    University of Rochester School of Medicine and Golisano Children s Hospital at Strong, Rochester, NY, USA
    Neurology 61:829-31. 2003
    ..They hypothesize that abnormal paroxysmal discharge of neurons in the cerebellar nuclei can generate myoclonus...
  8. ncbi request reprint Novel CLN3 mutation predicted to cause complete loss of protein function does not modify the classical JNCL phenotype
    Jennifer M Kwon
    Department of Neurology, 601 Elmwood Avenue, Box 631, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurosci Lett 387:111-4. 2005
    ..She had classical disease progression, suggesting that this mutation in CLN3 mimics the more prevalent 1 kb deletion and that progression of JNCL is predominantly the result of loss of CLN3 function...
  9. pmc Genotype does not predict severity of behavioural phenotype in juvenile neuronal ceroid lipofuscinosis (Batten disease)
    Heather R Adams
    Division of Child Neurology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Dev Med Child Neurol 52:637-43. 2010
    ..The secondary aim was to cross-validate the Child Behavior Checklist (CBCL) and the Unified Batten Disease Rating Scale (UBDRS), a disease-specific JNCL rating scale...
  10. pmc Neuropsychological symptoms of juvenile-onset batten disease: experiences from 2 studies
    Heather R Adams
    University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    J Child Neurol 22:621-7. 2007
    ....
  11. ncbi request reprint Standardized assessment of behavior and adaptive living skills in juvenile neuronal ceroid lipofuscinosis
    Heather Adams
    University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Dev Med Child Neurol 48:259-64. 2006
    ..Longitudinal assessment of behavioral and psychiatric symptoms and functional abilities is continuing and will provide much-needed data on the natural history of JNCL...
  12. doi request reprint Bilateral deep brain stimulation for treatment of medically refractory paroxysmal nonkinesigenic dyskinesia
    Christian B Kaufman
    Department of Neurosurgery, University of Rochester, New York, USA
    J Neurosurg 112:847-50. 2010
    ..This treatment strategy deserves further prospective investigation, clinical consideration, and refinement...
  13. ncbi request reprint Recent advances in Tourette syndrome research
    Roger L Albin
    Geriatrics Research, Education, and Clinical Center, Ann Arbor VAMC, Department of Neurology, University of Michigan, MI 48109, USA
    Trends Neurosci 29:175-82. 2006
    ..These lines of research have provided new pieces to the TS puzzle, and their increasing convergence is showing how those pieces can be put together...
  14. ncbi request reprint Neurobiology of basal ganglia and Tourette syndrome: basal ganglia circuits and thalamocortical outputs
    Jonathan W Mink
    Department of Neurology, Neurobiology and Anatomy, Pediatrics, University of Rochester, New York, USA
    Adv Neurol 99:89-98. 2006
    ..Continuing work on basic basal ganglia physiology, pathophysiology, and functional imaging in TS is advancing our knowledge of neural circuit abnormalities in TS, but much more work is still needed...
  15. ncbi request reprint Dysfunction of dopaminergic pathways in dystonia
    Joel S Perlmutter
    Departments of Neurology, Radiology, and Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri, USA
    Adv Neurol 94:163-70. 2004
  16. ncbi request reprint Safety and efficacy of subthalamic nucleus deep brain stimulation performed with limited intraoperative mapping for treatment of Parkinson's disease
    Samer D Tabbal
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neurosurgery 61:119-27; discussion 127-9. 2007
    ....
  17. pmc Unilateral subthalamic nucleus stimulation has a measurable ipsilateral effect on rigidity and bradykinesia in Parkinson disease
    Samer D Tabbal
    Department of Neurology, Washington University in St Louis, 4525 Scott Avenue, St Louis, MO 63130, USA
    Exp Neurol 211:234-42. 2008
    ..Bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN) improves motor function in Parkinson disease (PD). However, little is known about the quantitative effects on motor behavior of unilateral STN DBS...
  18. ncbi request reprint Deep brain stimulation
    Joel S Perlmutter
    Department of Neurology, Washington University School of Medicine, Washington University, St Louis, Missouri 63110, USA
    Annu Rev Neurosci 29:229-57. 2006
    ..Although we review relevant clinical issues, we emphasize the importance of current and future investigations on these topics...
  19. ncbi request reprint Postural tremor suppression is dependent on thalamic stimulation frequency
    Mwiza Ushe
    Department of Neurology, Washington University, St Louis, Missouri, USA
    Mov Disord 21:1290-2. 2006
    ....
  20. ncbi request reprint Relative risk of spread of symptoms among the focal onset primary dystonias
    Elliott M Weiss
    Department of Neurology, Washington University School of Medicine, St Louis, Missouri, USA
    Mov Disord 21:1175-81. 2006
    ..Different sites of onset of PTD confer different risks of spread, important for clinical prognosis. Different risks of spread may provide clues about underlying pathogenesis of adult-onset primary dystonias...
  21. ncbi request reprint Clinical features and comorbidity of mood fluctuations in Parkinson's disease
    Brad A Racette
    Department of Neurology, Washington University School of Medicine, 660 South Euclid Avenue, Box 8111, St Louis, MO 63110, USA
    J Neuropsychiatry Clin Neurosci 14:438-42. 2002
    ..This association remained after removing effects of age and disease duration...
  22. ncbi request reprint Psychogenic movement disorders in children
    Douglas B Kirsch
    Department of Neurology, University of Rochester School of Medicine and Strong Memorial Hospital, New York 14642, USA
    Pediatr Neurol 30:1-6. 2004
    ..Review of the current literature reveals a need for prospective trials to provide a solid foundation for better diagnosis and treatment of these disorders...
  23. ncbi request reprint Effect of stimulation frequency on tremor suppression in essential tremor
    Mwiza Ushe
    Department of Neurology, Washington University in St Louis, St Louis, Missouri, USA
    Mov Disord 19:1163-8. 2004
    ..Second, thalamic DBS provides tremor benefit in a graded manner and is not an all-or-nothing phenomenon...
  24. ncbi request reprint Classification and definition of disorders causing hypertonia in childhood
    Terence D Sanger
    Department of Neurology and Neurological Sciences, Stanford University Medical Center, Stanford, California 94305 5235, USA
    Pediatrics 111:e89-97. 2003
    ..The definitions presented here are designed to allow differentiation of clinical features even when more than 1 is present simultaneously...
  25. ncbi request reprint Movement disorders in children
    Bradley L Schlaggar
    Washington University School of Medicine and St Louis Children s Hospital, St Louis, MO, USA
    Pediatr Rev 24:39-51. 2003
  26. ncbi request reprint Masturbation in infancy and early childhood presenting as a movement disorder: 12 cases and a review of the literature
    Michele L Yang
    Department of Child Neurology, Children s Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Pediatrics 116:1427-32. 2005
    ..The purpose of this case series is to describe consistent features in young children with posturing accompanying masturbation...
  27. ncbi request reprint Abnormal circuit function in dystonia
    Jonathan W Mink
    Neurology 66:959. 2006
  28. ncbi request reprint Prospective open-label clinical trial of trihexyphenidyl in children with secondary dystonia due to cerebral palsy
    Terence D Sanger
    Stanford University, Stanford, California, USA
    J Child Neurol 22:530-7. 2007
    ..A larger, randomized prospective trial stratified by the presence or absence of hyperkinetic movements is needed to confirm these results...
  29. ncbi request reprint Using functional neuroimaging to study the brain's response to deep brain stimulation
    Tamara Hershey
    Neurology 66:1142-3. 2006

Research Grants12

  1. PATHOPHYSIOLOGY OF DYSTONIA AND PARKINSONISM
    Jonathan W Mink; Fiscal Year: 2010
    ..Better understanding of the pathophysiology may lead to new therapies or improved application of currently available therapies. ..
  2. PATHOPHYSIOLOGY OF DYSTONIA AND PARKINSONISM
    Jonathan Mink; Fiscal Year: 2009
    ..Better understanding of the pathophysiology may lead to new therapies or improved application of currently available therapies. ..
  3. Clinical and Neuropsychological Investigations in Batten Disease
    Jonathan Mink; Fiscal Year: 2007
    ..Although JNCL is a rare disease, our research has implications that can be generalized to the study of other degenerative neurologic disorders in children and for preparing translational clinical trials in these diseases. ..
  4. PATHOPHYSIOLOGY OF DYSTONIA AND PARKINSONISM
    Jonathan Mink; Fiscal Year: 2007
    ..Better understanding of the pathophysiology may lead to new therapies or improved application of currently available therapies. ..
  5. PATHOPHYSIOLOGY OF DYSTONIA AND PARKINSONISM
    Jonathan Mink; Fiscal Year: 2003
    ..Better understanding of the pathophysiology may lead to new therapies or improved application of currently available therapies. ..
  6. PATHOPHYSIOLOGY OF CHOREA
    Jonathan Mink; Fiscal Year: 2002
    ..abstract_text> ..
  7. Clinical and Neuropsychological Investigations in Batten Disease
    Jonathan W Mink; Fiscal Year: 2010
    ..Although JNCL is a rare disease, our research has implications that can be generalized to the study of other degenerative neurologic disorders in children and for preparing translational clinical trials in these diseases. ..