Guo li MingSummaryAffiliation: University of California Country: USA Publications
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Adaptation in the chemotactic guidance of nerve growth conesGuo li Ming
Division of Biology, University of California at San Diego, La Jolla, California 92093, USA
Nature 417:411-8. 2002..Such adaptive behaviour allows the growth cone to re-adjust its sensitivity over a wide range of concentrations of the guidance factor, an essential feature for long-range chemotaxis...- A CaMKII/calcineurin switch controls the direction of Ca(2+)-dependent growth cone guidanceZhexing Wen
Department of Neuroscience and Cell Biology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA
Neuron 43:835-46. 2004..Finally, CaMKII/CaN-PP1 also mediates netrin-1 guidance. Together, these findings establish a complex Ca2+ mechanism that targets the balance of CaMKII/CaN-PP1 activation to control distinct growth cone responses... - Focal adhesion kinase in netrin-1 signalingXiu Rong Ren
Department of Pathology, University of Alabama, Birmingham, Alabama 35294, USA
Nat Neurosci 7:1204-12. 2004..Taken together, these results indicate a new signaling mechanism for DCC, in which FAK is activated upon netrin-1 stimulation and mediates netrin-1 function; they also identify a critical role for FAK in axon navigation... - XTRPC1-dependent chemotropic guidance of neuronal growth conesSangwoo Shim
Institute for Cell Engineering, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, Maryland 21205, USA
Nat Neurosci 8:730-5. 2005..Thus, members of the TRPC family may serve as a key mediator for the Ca2+ influx that regulates axon guidance during development and inhibits axon regeneration in adulthood... 
BMP gradients steer nerve growth cones by a balancing act of LIM kinase and Slingshot phosphatase on ADF/cofilinZhexing Wen
Department of Neuroscience and Cell Biology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA
J Cell Biol 178:107-19. 2007..Together, we show that spatial regulation of ADF/cofilin activity controls the directional responses of the growth cone to BMP7, and Ca2+ influx through TRPC tilts the LIMK-SSH balance toward SSH-mediated repulsion...
A microfluidics-based turning assay reveals complex growth cone responses to integrated gradients of substrate-bound ECM molecules and diffusible guidance cuesC Joanne Wang
Department of Biomedical Engineering and Whitaker Institute of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21218, USA
Lab Chip 8:227-37. 2008....- Correction of humoral derangements from mutant superoxide dismutase 1 spinal cordYun-Sook Kim
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Ann Neurol 60:716-28. 2006..Correction of these abnormalities as a group, but not individually, restores axonal length to near normal. Such a "cocktail" approach to the treatment of amyotrophic lateral sclerosis should be investigated further... - Signaling of secreted semaphorins in growth cone steeringSangwoo Shim
Institute for Cell Engineering, Department of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21025, USA
Adv Exp Med Biol 600:52-60. 2007.... - Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brainXin Duan
Institute for Cell Engineering, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD 21205, USA
Cell 130:1146-58. 2007....