Chieko Mineo

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. pmc Inhibition of nitric oxide and antiphospholipid antibody-mediated thrombosis
    Chieko Mineo
    Department of Pediatrics, Division of Pulmonary and Vascular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9063, USA
    Curr Rheumatol Rep 15:324. 2013
  2. doi request reprint Functions of scavenger receptor class B, type I in atherosclerosis
    Chieko Mineo
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9063, USA
    Curr Opin Lipidol 23:487-93. 2012
  3. doi request reprint Regulation of eNOS in caveolae
    Chieko Mineo
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Adv Exp Med Biol 729:51-62. 2012
  4. ncbi request reprint Role of high-density lipoprotein and scavenger receptor B type I in the promotion of endothelial repair
    Chieko Mineo
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Trends Cardiovasc Med 17:156-61. 2007
  5. ncbi request reprint High density lipoprotein-induced endothelial nitric-oxide synthase activation is mediated by Akt and MAP kinases
    Chieko Mineo
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Biol Chem 278:9142-9. 2003
  6. ncbi request reprint HDL stimulation of endothelial nitric oxide synthase: a novel mechanism of HDL action
    Chieko Mineo
    Department of Pediatrics, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    Trends Cardiovasc Med 13:226-31. 2003
  7. pmc Coupling of Fcγ receptor I to Fcγ receptor IIb by SRC kinase mediates C-reactive protein impairment of endothelial function
    Nathan C Sundgren
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Circ Res 109:1132-40. 2011
  8. doi request reprint The scavenger receptor class B type I adaptor protein PDZK1 maintains endothelial monolayer integrity
    Weifei Zhu
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas, USA
    Circ Res 102:480-7. 2008
  9. ncbi request reprint High-density lipoprotein promotes endothelial cell migration and reendothelialization via scavenger receptor-B type I
    Divya Seetharam
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Circ Res 98:63-72. 2006
  10. pmc C-reactive protein inhibits insulin activation of endothelial nitric oxide synthase via the immunoreceptor tyrosine-based inhibition motif of FcgammaRIIB and SHIP-1
    Keiji Tanigaki
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Circ Res 104:1275-82. 2009

Collaborators

Detail Information

Publications32

  1. pmc Inhibition of nitric oxide and antiphospholipid antibody-mediated thrombosis
    Chieko Mineo
    Department of Pediatrics, Division of Pulmonary and Vascular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9063, USA
    Curr Rheumatol Rep 15:324. 2013
    ..This review will discuss recent findings that indicate a novel mechanism by which aPL antagonize endothelial cell production of nitric oxide and thereby promote thrombosis...
  2. doi request reprint Functions of scavenger receptor class B, type I in atherosclerosis
    Chieko Mineo
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9063, USA
    Curr Opin Lipidol 23:487-93. 2012
    ....
  3. doi request reprint Regulation of eNOS in caveolae
    Chieko Mineo
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Adv Exp Med Biol 729:51-62. 2012
    ..Thus, signaling events in caveolae invoked by known circulating cardiovascular disease risk factors have major impact on eNOS and endothelial cell phenotypes of importance to cardiovascular health and disease...
  4. ncbi request reprint Role of high-density lipoprotein and scavenger receptor B type I in the promotion of endothelial repair
    Chieko Mineo
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Trends Cardiovasc Med 17:156-61. 2007
    ..As such, signaling initiated by HDL-SR-BI promotes endothelial repair, and this novel mechanism of action may be critically involved in the impact of the lipoprotein on vascular health and disease...
  5. ncbi request reprint High density lipoprotein-induced endothelial nitric-oxide synthase activation is mediated by Akt and MAP kinases
    Chieko Mineo
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Biol Chem 278:9142-9. 2003
    ..These results indicate that HDL stimulates eNOS through common upstream, Src-mediated signaling, which leads to parallel activation of Akt and MAP kinases and their resultant independent modulation of the enzyme...
  6. ncbi request reprint HDL stimulation of endothelial nitric oxide synthase: a novel mechanism of HDL action
    Chieko Mineo
    Department of Pediatrics, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    Trends Cardiovasc Med 13:226-31. 2003
    ....
  7. pmc Coupling of Fcγ receptor I to Fcγ receptor IIb by SRC kinase mediates C-reactive protein impairment of endothelial function
    Nathan C Sundgren
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Circ Res 109:1132-40. 2011
    ..In mice, CRP actions on eNOS blunt carotid artery re-endothelialization...
  8. doi request reprint The scavenger receptor class B type I adaptor protein PDZK1 maintains endothelial monolayer integrity
    Weifei Zhu
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas, USA
    Circ Res 102:480-7. 2008
    ..Thus, PDZK1 is uniquely required for HDL/SR-BI signaling in endothelium, and through these mechanisms, it is critically involved in the maintenance of endothelial monolayer integrity...
  9. ncbi request reprint High-density lipoprotein promotes endothelial cell migration and reendothelialization via scavenger receptor-B type I
    Divya Seetharam
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Circ Res 98:63-72. 2006
    ..Furthermore, reendothelialization is impaired in SR-BI(-/-) mice. Thus, HDL stimulates endothelial cell migration via SR-BI-initiated signaling, and these mechanisms promote endothelial monolayer integrity in vivo...
  10. pmc C-reactive protein inhibits insulin activation of endothelial nitric oxide synthase via the immunoreceptor tyrosine-based inhibition motif of FcgammaRIIB and SHIP-1
    Keiji Tanigaki
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Circ Res 104:1275-82. 2009
    ..These findings provide mechanistic linkage among CRP, impaired insulin signaling in endothelium, and greater cardiovascular disease risk in type 2 diabetes...
  11. ncbi request reprint Direct Interactions with G alpha i and G betagamma mediate nongenomic signaling by estrogen receptor alpha
    Premlata Kumar
    Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390 9063, USA
    Mol Endocrinol 21:1370-80. 2007
    ..Thus, through direct interactions, ER alpha mediates a novel mechanism of G protein activation that provides greater diversity of function of both the steroid hormone receptor and G proteins...
  12. ncbi request reprint C-reactive protein downregulates endothelial NO synthase and attenuates reendothelialization in vivo in mice
    Randall Schwartz
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Circ Res 100:1452-9. 2007
    ..Thus, CRP downregulates eNOS and attenuates reendothelialization in vivo in mice, and this action of CRP on eNOS is mediated at the level of gene transcription...
  13. pmc Point mutations in the ERα Gαi binding domain segregate nonnuclear from nuclear receptor function
    Qian Wu
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Mol Endocrinol 27:2-11. 2013
    ..Thus, the point mutants ERα-R256A and ERα-D258A in the receptor GαI-binding domain provide genetic segregation of nonnuclear from nuclear ERα function...
  14. pmc Scavenger receptor class B type I is a plasma membrane cholesterol sensor
    Sonika Saddar
    Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA
    Circ Res 112:140-51. 2013
    ..The C-terminal transmembrane domain uniquely interacts with plasma membrane (PM) cholesterol...
  15. pmc Cholesterol binding, efflux, and a PDZ-interacting domain of scavenger receptor-BI mediate HDL-initiated signaling
    Chatchawin Assanasen
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Clin Invest 115:969-77. 2005
    ..Thus, HDL signaling requires cholesterol binding and efflux and C-terminal domains of SR-BI, and SR-BI serves as a cholesterol sensor on the plasma membrane...
  16. ncbi request reprint Dissecting the basis of nongenomic activation of endothelial nitric oxide synthase by estradiol: role of ERalpha domains with known nuclear functions
    Ken L Chambliss
    Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA
    Mol Endocrinol 19:277-89. 2005
    ..Thus, dimerization is not required for ERalpha coupling to eNOS; however, NLS2/NLS3 plays a role in Src activation, and the DNA binding region is involved in the dynamic interaction between ERalpha and PI3 kinase...
  17. pmc Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice
    Ken L Chambliss
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9063, USA
    J Clin Invest 120:2319-30. 2010
    ..These processes potentially could be harnessed to provide vascular benefit without increasing the risk of uterine or breast cancer...
  18. pmc C-reactive protein causes insulin resistance in mice through Fcγ receptor IIB-mediated inhibition of skeletal muscle glucose delivery
    Keiji Tanigaki
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Diabetes 62:721-31. 2013
    ..Thus, CRP causes insulin resistance in mice through FcγRIIB-mediated inhibition of skeletal muscle glucose delivery...
  19. doi request reprint Signaling by the high-affinity HDL receptor scavenger receptor B type I
    Sonika Saddar
    Division of Pulmonary and Vascular Biology, The Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Arterioscler Thromb Vasc Biol 30:144-50. 2010
    ..Further understanding of signaling by SR-BI will optimize the capacity to harness the mechanisms of action of HDL-SR-BI for cardiovascular benefit...
  20. pmc Non-nuclear estrogen receptor signaling in the endothelium
    Qian Wu
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Biol Chem 286:14737-43. 2011
    ..In this minireview, the features of ERα and protein-protein interactions that enable it to invoke extranuclear signaling in the endothelium and the consequences of that signaling are discussed...
  21. ncbi request reprint Circulating cardiovascular disease risk factors and signaling in endothelial cell caveolae
    Chieko Mineo
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX, USA
    Cardiovasc Res 70:31-41. 2006
    ..Thus, signaling events in caveolae invoked by known circulating cardiovascular disease risk factors have major impact on endothelial cell phenotypes of importance to cardiovascular health and disease...
  22. pmc Antiphospholipid antibodies promote leukocyte-endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2
    Sangeetha Ramesh
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Clin Invest 121:120-31. 2011
    ..Our results suggest that novel therapies for APS can now be developed targeting these mechanisms...
  23. ncbi request reprint The Cholesterol Metabolite 27-Hydroxycholesterol Promotes Atherosclerosis via Proinflammatory Processes Mediated by Estrogen Receptor Alpha
    Michihisa Umetani
    Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Cell Metab 20:172-82. 2014
    ..Strategies to lower 27HC may complement approaches targeting cholesterol to prevent vascular disease. ..
  24. ncbi request reprint FcgammaRIIB mediates C-reactive protein inhibition of endothelial NO synthase
    Chieko Mineo
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Circ Res 97:1124-31. 2005
    ..Thus FcgammaRIIB mediates CRP inhibition of eNOS via PP2A, providing a mechanistic link between CRP and endothelial dysfunction...
  25. pmc HDL action on the vascular wall: is the answer NO?
    Philip W Shaul
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Clin Invest 113:509-13. 2004
    ..A new study shows that HDL-associated lysophospholipids stimulate the production of the potent antiatherogenic signaling molecule NO by the vascular endothelium...
  26. ncbi request reprint Endothelial and antithrombotic actions of HDL
    Chieko Mineo
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390 9063, USA
    Circ Res 98:1352-64. 2006
    ..With further investigation and resulting greater depth of understanding, these mechanisms may be harnessed to provide new prophylactic and therapeutic strategies to combat atherosclerosis and thrombotic disorders...
  27. pmc Regulation of signal transduction by HDL
    Chieko Mineo
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA
    J Lipid Res 54:2315-24. 2013
    ..Further investigation of the processes underlying HDL and apoA-I modulation of intracellular signaling will potentially reveal new prophylactic and therapeutic strategies to optimize both cardiovascular and metabolic health. ..
  28. ncbi request reprint Recent insights into non-nuclear actions of estrogen receptor alpha
    Subhashis Banerjee
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9063, USA
    Steroids 81:64-9. 2014
    ..Further research into the non-nuclear capacities by which ER modulate cellular behavior is essential to ultimately harnessing these processes for therapeutic gain in numerous disease contexts. ..
  29. pmc 27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth
    Qian Wu
    Department of Pediatrics, Division of Pulmonary and Vascular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Cell Rep 5:637-45. 2013
    ..Moreover, 27HC is produced by MCF-7 cells, and it stimulates cell-autonomous, ER-dependent, and GDNF-RET-dependent cell proliferation. Thus, 27HC is a locally modulated, nonaromatized ER ligand that promotes ER+ breast tumor growth. ..
  30. pmc Novel biological functions of high-density lipoprotein cholesterol
    Chieko Mineo
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Circ Res 111:1079-90. 2012
    ..Further work on the many mechanisms of HDL action promises to reveal new prophylactic and therapeutic strategies to optimize both cardiovascular and metabolic health...
  31. pmc PON-dering differences in HDL function in coronary artery disease
    Chieko Mineo
    Division of Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9063, USA
    J Clin Invest 121:2545-8. 2011
    ....
  32. ncbi request reprint Biochemical consequences of the NOS3 Glu298Asp variation in human endothelium: altered caveolar localization and impaired response to shear
    Mandar S Joshi
    Center for Cardiovascular Medicine, Columbus Children s Research Institute, 700 Children s Dr, Columbus, OH 43205, USA
    FASEB J 21:2655-63. 2007
    ....