Research Topics
| Stacey E MillsSummaryAffiliation: University of Virginia Country: USA Publications
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Publications
Neuroectodermal neoplasms of the head and neck with emphasis on neuroendocrine carcinomasStacey E Mills
Robert E Fechner Laboratory of Surgical Pathology, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
Mod Pathol 15:264-78. 2002..This article reviews and updates our understanding of neuroectodermal neoplasms arising in the head and neck. The focus is on tumors that exclusively involve this region or show a strong predilection to occur here...
Immunophenotypic differences between intestinal-type and low-grade papillary sinonasal adenocarcinomas: an immunohistochemical study of 22 cases utilizing CDX2 and MUC2Helen P Cathro
Department of Pathology, University of Virginia, Jefferson Park Avenue, Charlottesville, VA 22908, USA
Am J Surg Pathol 28:1026-32. 2004..Immunohistochemical staining for CDX2, MUC2, and differential cytokeratins does not differentiate metastatic colorectal from primary sinonasal intestinal-type adenocarcinoma...
Sarcoidosis of the breast: An unusual presentation of a systemic diseaseBrandi T Nicholson
Department of Radiology, University of Virginia, Charlottesville, Virgina 22908, USA
Breast J 13:99-100. 2007
Evidence-based principles and practices in pathology: selected problem areasMark R Wick
Department of Pathology, University of Virginia Health System, Charlottesville, Virginia 22908 0214, USA
Semin Diagn Pathol 22:116-25. 2005..The concepts illustrating departures from EBM are discussed for each of those topics...
Atypical small acinar proliferation: biopsy artefact or distinct pathological entity?Sarah C Flury
Department of Urology, University of Virginia Health System, Charlottesville, VA, USA
BJU Int 99:780-5. 2007....
Evaluation of surgical margins in anatomic pathology: technical, conceptual, and clinical considerationsMark R Wick
Department of Pathology, Robert E Fechner Laboratory of Surgical Pathology and Cytopathology, University of Virginia Health System, Charlottesville, VA 22908 0214, USA
Semin Diagn Pathol 19:207-18. 2002..This review considers conceptual data now available on surgical margins, provides a working approach to the generic assessment of marginal surfaces, and presents organ- and tumor- specific information pertaining to this area of practice...
Encapsulated papillary oncocytic neoplasms of the thyroid: morphologic, immunohistochemical, and molecular analysis of 18 casesRandall Lyndon Woodford
Department of Pathology, University of Virginia Health System, Charlottesville, VA 22908, USA
Am J Surg Pathol 34:1582-90. 2010..Our results confirm that EPONs are histologically, immunohistochemically, and molecularly distinct from papillary thyroid carcinoma and seem to be most related to follicular neoplasms...
Podoplanin is a better immunohistochemical marker for sarcomatoid mesothelioma than calretininDiana M Padgett
Department of Pathology, University of Virginia Health System, Charlottesville, VA 22908, USA
Am J Surg Pathol 32:123-7. 2008..These findings suggest that cytoplasmic podoplanin expression may be useful in the diagnosis of sarcomatoid mesothelioma, although it should be used with caution on biopsy material...
Hyalinizing trabecular adenoma of the thyroid revisited: a histologic and immunohistochemical study of thyroid lesions with prominent trabecular architecture and sclerosisMary T Galgano
Robert E Fechner Laboratory of Surgical Pathology, University of Virginia, VA, USA
Am J Surg Pathol 30:1269-73. 2006....
Case-matched comparison of contemporary radiation therapy to surgery in patients with locally advanced prostate cancerSophie G Fletcher
Department of Urology, University of Virginia Health System, Charlottesville, VA 22908, USA
Int J Radiat Oncol Biol Phys 66:1092-9. 2006..44 (0.26-0.74; p = 0.002). CONCLUSIONS: High-risk prostate cancer patients receiving multimodality radiation therapy (BTC) display apparently superior BFS compared with those receiving surgery (RP) or brachytherapy alone (BTM)...
alpha-methylacyl coenzyme A racemase is immunoreactive in extramammary Paget diseaseDaniel C Mayes
The Department of Pathology, University of Virginia Health System, Charlottesville, VA 22908, USA
Am J Clin Pathol 127:567-71. 2007..We found immunoreactivity for AMACR in 15 (71%) of 21 EMPD cases overall, in 5 (56%) of 9 cases in women, and in 10 (83%) of 12 cases in men. AMACR immunoreactivity is a common finding in EMPD in men and women...
Gleason scores of prostate biopsy and radical prostatectomy specimens over the past 10 years: is there evidence for systematic upgrading?Emily B Smith
Department of Urology, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
Cancer 94:2282-7. 2002..In contrast, grade has shifted heavily toward moderate differentiation. The authors sought to test the hypothesis that such changes in grade in part may be because of trends among pathologists to upgrade similar specimens over time...
KIT and RCC are useful in distinguishing chromophobe renal cell carcinoma from the granular variant of clear cell renal cell carcinomaHuan-You Wang
Robert E. Fechner Surgical Pathology Laboratory, Department of Pathology, University of Virginia Health Sciences Center, Charlottesville, VA 22908-0214, USA
Am J Surg Pathol 29:640-6. 2005..Colloidal iron staining aided in this distinction for the majority of the chromophobe renal cell carcinomas (more than 80% positive) and renal oncocytomas (close to 60% negative)...
A histologic and immunohistochemical study describing the diversity of tumors classified as sinonasal high-grade nonintestinal adenocarcinomasEdward B Stelow
Department of Pathology, University of Virginia, Charlottesville, USA
Am J Surg Pathol 35:971-80. 2011..High-grade nonintestinal SNACs are more common in men and, although they occur over a wide age range, they are much more common in older individuals. Histologically, they show a great deal of heterogeneity...
Human papillomavirus-associated squamous cell carcinoma of the upper aerodigestive tractEdward B Stelow
Department of Pathology, The University of Virginia, Charlottesville, VA, USA
Am J Surg Pathol 34:e15-24. 2010..We further review the prognosis and treatment of these tumors. Finally, a detailed discussion is provided regarding the differential diagnosis that must be considered when confronting these squamous neoplasms...
Low-grade sinonasal adenocarcinomas: the association with and distinction from respiratory epithelial adenomatoid hamartomas and other glandular lesionsVickie Y Jo
Department of Pathology, University of Virginia, Charlottesville, VA 22908, USA
Am J Surg Pathol 33:401-8. 2009..No basal cells or myoepithelial differentiation was seen with immunohistochemical stains for p63 and 34betaE12. This association of low-grade tubular SNACs with REAHs suggests that REAHs may be related to some adenocarcinomas...
The cytologic features of sinonasal undifferentiated carcinoma and olfactory neuroblastomaAndrew M Bellizzi
Department of Pathology, University of Virginia Health System, Charlottesville, VA 22908, USA
Am J Clin Pathol 129:367-76. 2008..Homer Wright rosettes were encountered in 9 cases (90%). We believe that in the appropriate clinical context, a specific cytologic diagnosis should be possible...
Interpretation of RET immunostaining in follicular lesions of the thyroidLisa A Cerilli
Robert E Fechner Laboratory of Surgical Pathology, University of Virginia Health Sciences Center, Charlottesville, USA
Am J Clin Pathol 118:186-93. 2002..Further study is warranted to determine whether this represents activation by gene fusion or some other mechanism in this subset of thyroid neoplasms...
Salivary-type neoplasms of the breast and lungAudrey K Bennett
Robert E. Fecuhner Division of Surgical Pathology, Department of Pathology, University of Virginia Medical Center, Charlottesville, VA 22908, USA
Semin Diagn Pathol 20:279-304. 2003..This represents a potential area for future growth in further clarifying these tumors and their behavior...
Papillary squamous cell carcinoma of the head and neck: frequent association with human papillomavirus infection and invasive carcinomaVickie Y Jo
Department of Pathology, University of Virginia, Charlottesville, VA, USA
Am J Surg Pathol 33:1720-4. 2009..Given the better prognosis of HPV-associated SCCs of the upper aerodigestive tract, it may be prudent to report the p16 and HPV status of these tumors when they are encountered...
p63 Expression in olfactory neuroblastoma and other small cell tumors of the sinonasal tractT David Bourne
Robert E Fechner Surgical Pathology Laboratory, University of Virginia, Department of Pathology, Charlottesville, VA 22908 0214, USA
Am J Clin Pathol 130:213-8. 2008..In particular, p63 helps distinguish nonkeratinizing and undifferentiated NPC subtypes from SNUC...
Adenocarcinoma of the upper aerodigestive tractEdward B Stelow
Department of Pathology, University of Virginia, Charlottesville, USA
Adv Anat Pathol 17:262-9. 2010..Clinical, histologic, and immunohistochemical features and differential diagnoses are discussed...
Distinguishing breast carcinoma from Müllerian serous carcinoma with mammaglobin and mesothelinWilliam A Kanner
Department of Pathology, University of Virginia Health System, Charlottesville, Virginia 22908 0214, USA
Int J Gynecol Pathol 27:491-5. 2008..Mesothelin is extremely specific in this scenario but can be technically challenging to interpret due to the common patchy, focal staining...
NUT rearrangement in undifferentiated carcinomas of the upper aerodigestive tractEdward B Stelow
Department of Pathology, University of Virginia, Charlottesville, VA, USA
Am J Surg Pathol 32:828-34. 2008..The histologic features of these tumors are described in detail...
Anorectal malignant melanoma: morphologic and immunohistochemical featuresDeborah J Chute
Department of Pathology, University of Virginia Health System, Charlottesville, VA 22908, USA
Am J Clin Pathol 126:93-100. 2006..Immunohistochemical staining is similar to cutaneous melanomas. Expression of KIT was present frequently, including cases with spindle cell morphologic features, in which it may lead to confusion with gastrointestinal stromal tumors...
Most osteomalacia-associated mesenchymal tumors are a single histopathologic entity: an analysis of 32 cases and a comprehensive review of the literatureAndrew L Folpe
Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA
Am J Surg Pathol 28:1-30. 2004..Recognition of PMTMCT is critical, as complete resection cures intractable OO. Immunohistochemistry and RT-PCR for FGF-23 confirm the role of this protein in PMTMCT-associated OO...
Epstein-Barr virus plays no role in the tumorigenesis of small-cell carcinoma of the lungPeiguo G Chu
Department of Pathology, City of Hope National Medical Center, Duarte, CA 91010, USA
Mod Pathol 17:158-64. 2004....
Sporadic medullary carcinoma of the colon: a clinicopathologic comparison with nonhereditary poorly differentiated enteric-type adenocarcinoma and neuroendocrine colorectal carcinomaMark R Wick
Department of Pathology, University of Virginia Health System, Charlottesville 22908-0214, USA
Am J Clin Pathol 123:56-65. 2005..Medullary CRC seems to be a distinct clinicopathologic variant of CRC, which does not have a neuroendocrine lineage. The biologic behavior of MCRC was better than that of ECRC or NEC...
"Undifferentiated" small round cell tumors of the sinonasal tract: differential diagnosis updateJulia C Iezzoni
Robert E. Fechner Laboratory of Surgical Pathology, Department of Pathology, University of Virginia Health System, Charlottesville 22908, USA
Am J Clin Pathol 124:S110-21. 2005....
