Research Topics
| Melissa B MillerSummaryAffiliation: University of North Carolina Country: USA Publications
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Detail Information
Publications
Molecular diagnosis of infectious diseasesMelissa B Miller
Molecular Microbiology Laboratory, School of Medicine, University of North Carolina at Chapel Hill, NC 27599, USA
N C Med J 68:115-8. 2007
Comparison of conventional susceptibility testing, penicillin-binding protein 2a latex agglutination testing, and mecA real-time PCR for detection of oxacillin resistance in Staphylococcus aureus and coagulase-negative StaphylococcusMelissa B Miller
University of North Carolina Hospitals, University of North Carolina School of Medicine, Campus Box 7525, Chapel Hill, NC 27599 7525, USA
J Clin Microbiol 43:3450-2. 2005..Inoculum volume and induction with oxacillin were PBP 2a testing variables. For coagulase-negative Staphylococcus, an increased inoculum volume of 10 microl greatly reduced the number of isolates requiring induction...- Posttransplantation disseminated coccidioidomycosis acquired from donor lungsMelissa B Miller
Clinical Microbiology Immunology Laboratories, University of North Carolina Hospitals, Chapel Hill, North Carolina 27514, USA
J Clin Microbiol 42:2347-9. 2004..Immunosuppressive therapy of the transplant recipient likely reactivated latent Coccidioides infection in the donor lungs, leading to posttransplant coccidioidomycosis... - Performance of Xpert MTB/RIF RUO assay and IS6110 real-time PCR for Mycobacterium tuberculosis detection in clinical samplesMelissa B Miller
UNC School of Medicine, Department of Pathology and Laboratory Medicine, Campus Box 7525, Chapel Hill, NC 27599 7525, USA
J Clin Microbiol 49:3458-62. 2011..tuberculosis isolates in smear-positive pulmonary and extrapulmonary specimens, while the sensitivity of the detection of M. tuberculosis isolates in smear-negative specimens was variable... - Basic concepts of microarrays and potential applications in clinical microbiologyMelissa B Miller
Department of Pathology and Laboratory Medicine, School of Medicine, University of North Carolina, Campus Box 7525, Chapel Hill, NC 27599 7525, USA
Clin Microbiol Rev 22:611-33. 2009.... - Prevalence and risk factor analysis for methicillin-resistant Staphylococcus aureus nasal colonization in children attending child care centersMelissa B Miller
UNC School of Medicine, Department of Pathology and Laboratory Medicine, Campus Box 7525, Chapel Hill, NC 27599, USA
J Clin Microbiol 49:1041-7. 2011..The low frequency of colonization observed highlights the need for a large multicenter study to determine risk factors for MRSA colonization and subsequent infection in this highly susceptible population... 
Treatment intensity and characteristics of MRSA infection in CFMarianne S Muhlebach
Department of Pediatrics, University of North Carolina, Chapel Hill, NC 27599 7217, USA
J Cyst Fibros 10:201-6. 2011..This study assesses the impact of MRSA and different MRSA types on clinical outcomes, medication use, and antibiotic sensitivities...- Prevalence of community-associated methicillin-resistant Staphylococcus aureus in patients with cystic fibrosisJennifer S Goodrich
Clinical Microbiology Immunology Laboratories, University of North Carolina Hospitals, North Carolina 27514, USA
J Clin Microbiol 47:1231-3. 2009.... - Role of hospital surfaces in the transmission of emerging health care-associated pathogens: norovirus, Clostridium difficile, and Acinetobacter speciesDavid J Weber
Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Am J Infect Control 38:S25-33. 2010..Current hand hygiene guidelines and recommendations for surface cleaning/disinfection should be followed in managing outbreaks because of these emerging pathogens... - Retrospective and prospective verification of the Cepheid Xpert influenza virus assayElena B Popowitch
UNC School of Medicine, Department of Pathology and Laboratory Medicine, Campus Box 7525, Chapel Hill, NC 27599 7525, USA
J Clin Microbiol 49:3368-9. 2011..Nasopharyngeal specimen sensitivities were 100% for seasonal influenza A/H1 virus and influenza A/H3 virus, 90% for influenza A/2009/H1N1 virus, and 95% for influenza B virus... - Comparison of culture and 2 real-time polymerase chain reaction assays to detect group B Streptococcus during antepartum screeningJennifer S Goodrich
Department of Pathology and Laboratory Medicine, University of North Carolina Hospitals, Chapel Hill, NC 27599, USA
Diagn Microbiol Infect Dis 59:17-22. 2007..In our hands, the sensitivity/specificity of the LC Strep B ASR was 100%/95.9%, and the BD-StrepB test was 92.5%/92.5% using culture as the gold standard... - Should interferon gamma release assays become the standard method for screening patients for Mycobacterium tuberculosis infections in the United States?Thomas S Alexander
University of North Carolina at Chapel Hill, Campus Box 7525, Chapel Hill, North Carolina 27599 7525, USA
J Clin Microbiol 49:2086-92. 2011.... - Are lower airway or throat cultures predictive of sinus bacteriology in cystic fibrosis?Marianne S Muhlebach
Department of Pediatrics, University of North Carolina, 27599 7220, USA
Pediatr Pulmonol 41:445-51. 2006..We conclude that S. aureus is an important pathogen in pediatric CF sinusitis, and that BALF or oropharyngeal cultures are poor predictors for organisms present in the sinuses... - Comparison of the Biofire FilmArray RP, Genmark eSensor RVP, Luminex xTAG RVPv1, and Luminex xTAG RVP Fast Multiplex Assays for Detection of Respiratory VirusesElena B Popowitch
University of North Carolina Health Care System, Chapel Hill, North Carolina, USA
J Clin Microbiol 51:1528-33. 2013..Hands-on time and time to result were recorded and ease of use was assessed to generate a complete profile of each assay... - Ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with wild-type CMV in her plasmaHart B Moss
Department of Ophthalmology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA
J Clin Microbiol 50:1796-9. 2012..Quantifying CMV from aqueous fluid was valuable for monitoring the clinical response and predicting resistance... - Evaluation of a non-invasive method to detect cytomegalovirus (CMV)-DNA in stool samples of patients with inflammatory bowel disease (IBD): a pilot studyHans H Herfarth
Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina, Bioinformatics Bldg, CB 7080, Chapel Hill, NC, 27599, USA
Dig Dis Sci 55:1053-8. 2010..The aim of this pilot study was to investigate the diagnostic efficacy of quantitative polymerase chain reaction (PCR) to detect CMV DNA in stool samples of IBD patients... - Comparative evaluation of the Nanosphere Verigene RV+ assay and the Simplexa Flu A/B & RSV kit for detection of influenza and respiratory syncytial virusesKevin Alby
Clinical Microbiology Immunology Laboratories, UNC Health Care, Chapel Hill, North Carolina, USA
J Clin Microbiol 51:352-3. 2013..7% for influenza B virus, and 100% and 100% for respiratory syncytial virus (RSV), while the Simplexa test sensitivities and specificities were 82.8 and 99.7%, 76.2 and 100%, and 94.6 and 100%, respectively... - High-level human herpesvirus-6 viremia associated with onset of Stevens-Johnson syndrome: report of two casesAmanda F Peppercorn
Department of Medicine, University of North Carolina, School of Medicine, Chapel Hill, USA
J Burn Care Res 31:365-8. 2010.... - Preventing healthcare-associated Aspergillus infections: review of recent CDC/HICPAC recommendationsDavid J Weber
Division of Infectious Diseases, UNC School of Medicine, Chapel Hill, NC 27599 7030, USA
Med Mycol 47:S199-209. 2009.... - Comparison of Cepheid's analyte-specific reagents with BD directigen for detection of respiratory syncytial virusJennifer S Goodrich
University of North Carolina Hospitals, Clinical Microbiology Immunology Laboratory, Chapel Hill, NC, USA
J Clin Microbiol 45:604-6. 2007..The Directigen RSV assay resulted in a 23% false-negative rate, using PCR and chart review as the gold standard, indicating that rapid RSV PCR results would be advantageous... - Prevalence of vancomycin-resistant enterococcus in prenatal screening culturesMelissa B Miller
Clinical Microbiology-Immunology Laboratories, University of North Carolina Hospitals, Chapel Hill, North Carolina 27514, USA
J Clin Microbiol 42:855-7. 2004..Because of potential postpartum infections due to vancomycin-resistant enterococci (VRE) and the possible spread of vancomycin resistance, the prevalence of VRE in prenatal screening cultures was determined... - Laboratory aspects of management of chronic pulmonary infections in patients with cystic fibrosisMelissa B Miller
Clinical Microbiology-Immunology Laboratories, University of North Carolina Hospitals, University of North Carolina School of Medicine Chapel Hill, North Carolina 27514, USA
J Clin Microbiol 41:4009-15. 2003 - CsrA and three redundant small RNAs regulate quorum sensing in Vibrio choleraeDerrick H Lenz
Department of Molecular Biology, Howard Hughes Medical Institute, Princeton University, Princeton, NJ 08544-1014, USA
Mol Microbiol 58:1186-202. 2005..The VarS/VarA-CsrA/BCD system converges with the V. cholerae quorum-sensing systems to regulate the expression of the Qrr sRNAs, and thus, the entire quorum-sensing regulon... - Parallel quorum sensing systems converge to regulate virulence in Vibrio choleraeMelissa B Miller
Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA
Cell 110:303-14. 2002..cholerae. This quorum sensing apparatus is unusually complex, as it is composed of at least three parallel signaling channels. We show that in V. cholerae these communication systems converge to control virulence... - Quorum-sensing regulators control virulence gene expression in Vibrio choleraeJun Zhu
Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 99:3129-34. 2002..Together these data suggest a role for quorum sensing in modulating expression of blocks of virulence genes in a reciprocal fashion in vivo...