Melissa B Miller

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. pmc Prevalence and risk factor analysis for methicillin-resistant Staphylococcus aureus nasal colonization in children attending child care centers
    Melissa B Miller
    UNC School of Medicine, Department of Pathology and Laboratory Medicine, Campus Box 7525, Chapel Hill, NC 27599, USA
    J Clin Microbiol 49:1041-7. 2011
  2. pmc Basic concepts of microarrays and potential applications in clinical microbiology
    Melissa B Miller
    Department of Pathology and Laboratory Medicine, School of Medicine, University of North Carolina, Campus Box 7525, Chapel Hill, NC 27599 7525, USA
    Clin Microbiol Rev 22:611-33. 2009
  3. pmc Performance of Xpert MTB/RIF RUO assay and IS6110 real-time PCR for Mycobacterium tuberculosis detection in clinical samples
    Melissa B Miller
    UNC School of Medicine, Department of Pathology and Laboratory Medicine, Campus Box 7525, Chapel Hill, NC 27599 7525, USA
    J Clin Microbiol 49:3458-62. 2011
  4. pmc Posttransplantation disseminated coccidioidomycosis acquired from donor lungs
    Melissa B Miller
    Clinical Microbiology Immunology Laboratories, University of North Carolina Hospitals, Chapel Hill, North Carolina 27514, USA
    J Clin Microbiol 42:2347-9. 2004
  5. pmc Comparison of conventional susceptibility testing, penicillin-binding protein 2a latex agglutination testing, and mecA real-time PCR for detection of oxacillin resistance in Staphylococcus aureus and coagulase-negative Staphylococcus
    Melissa B Miller
    University of North Carolina Hospitals, University of North Carolina School of Medicine, Campus Box 7525, Chapel Hill, NC 27599 7525, USA
    J Clin Microbiol 43:3450-2. 2005
  6. ncbi request reprint Molecular diagnosis of infectious diseases
    Melissa B Miller
    Molecular Microbiology Laboratory, School of Medicine, University of North Carolina at Chapel Hill, NC 27599, USA
    N C Med J 68:115-8. 2007
  7. doi request reprint Treatment intensity and characteristics of MRSA infection in CF
    Marianne S Muhlebach
    Department of Pediatrics, University of North Carolina, Chapel Hill, NC 27599 7217, USA
    J Cyst Fibros 10:201-6. 2011
  8. pmc Prevalence of community-associated methicillin-resistant Staphylococcus aureus in patients with cystic fibrosis
    Jennifer S Goodrich
    Clinical Microbiology Immunology Laboratories, University of North Carolina Hospitals, North Carolina 27514, USA
    J Clin Microbiol 47:1231-3. 2009
  9. pmc Clinical outcomes with rapid detection of methicillin-resistant and methicillin-susceptible Staphylococcus aureus isolates from routine blood cultures
    Nicole C Nicolsen
    UNC Health Care, Department of Pharmacy, Chapel Hill, North Carolina, USA
    J Clin Microbiol 51:4126-9. 2013
  10. pmc Comparative evaluation of the Nanosphere Verigene RV+ assay and the Simplexa Flu A/B & RSV kit for detection of influenza and respiratory syncytial viruses
    Kevin Alby
    Clinical Microbiology Immunology Laboratories, UNC Health Care, Chapel Hill, North Carolina, USA
    J Clin Microbiol 51:352-3. 2013

Collaborators

Detail Information

Publications28

  1. pmc Prevalence and risk factor analysis for methicillin-resistant Staphylococcus aureus nasal colonization in children attending child care centers
    Melissa B Miller
    UNC School of Medicine, Department of Pathology and Laboratory Medicine, Campus Box 7525, Chapel Hill, NC 27599, USA
    J Clin Microbiol 49:1041-7. 2011
    ..The low frequency of colonization observed highlights the need for a large multicenter study to determine risk factors for MRSA colonization and subsequent infection in this highly susceptible population...
  2. pmc Basic concepts of microarrays and potential applications in clinical microbiology
    Melissa B Miller
    Department of Pathology and Laboratory Medicine, School of Medicine, University of North Carolina, Campus Box 7525, Chapel Hill, NC 27599 7525, USA
    Clin Microbiol Rev 22:611-33. 2009
    ....
  3. pmc Performance of Xpert MTB/RIF RUO assay and IS6110 real-time PCR for Mycobacterium tuberculosis detection in clinical samples
    Melissa B Miller
    UNC School of Medicine, Department of Pathology and Laboratory Medicine, Campus Box 7525, Chapel Hill, NC 27599 7525, USA
    J Clin Microbiol 49:3458-62. 2011
    ..tuberculosis isolates in smear-positive pulmonary and extrapulmonary specimens, while the sensitivity of the detection of M. tuberculosis isolates in smear-negative specimens was variable...
  4. pmc Posttransplantation disseminated coccidioidomycosis acquired from donor lungs
    Melissa B Miller
    Clinical Microbiology Immunology Laboratories, University of North Carolina Hospitals, Chapel Hill, North Carolina 27514, USA
    J Clin Microbiol 42:2347-9. 2004
    ..Immunosuppressive therapy of the transplant recipient likely reactivated latent Coccidioides infection in the donor lungs, leading to posttransplant coccidioidomycosis...
  5. pmc Comparison of conventional susceptibility testing, penicillin-binding protein 2a latex agglutination testing, and mecA real-time PCR for detection of oxacillin resistance in Staphylococcus aureus and coagulase-negative Staphylococcus
    Melissa B Miller
    University of North Carolina Hospitals, University of North Carolina School of Medicine, Campus Box 7525, Chapel Hill, NC 27599 7525, USA
    J Clin Microbiol 43:3450-2. 2005
    ..Inoculum volume and induction with oxacillin were PBP 2a testing variables. For coagulase-negative Staphylococcus, an increased inoculum volume of 10 microl greatly reduced the number of isolates requiring induction...
  6. ncbi request reprint Molecular diagnosis of infectious diseases
    Melissa B Miller
    Molecular Microbiology Laboratory, School of Medicine, University of North Carolina at Chapel Hill, NC 27599, USA
    N C Med J 68:115-8. 2007
  7. doi request reprint Treatment intensity and characteristics of MRSA infection in CF
    Marianne S Muhlebach
    Department of Pediatrics, University of North Carolina, Chapel Hill, NC 27599 7217, USA
    J Cyst Fibros 10:201-6. 2011
    ..This study assesses the impact of MRSA and different MRSA types on clinical outcomes, medication use, and antibiotic sensitivities...
  8. pmc Prevalence of community-associated methicillin-resistant Staphylococcus aureus in patients with cystic fibrosis
    Jennifer S Goodrich
    Clinical Microbiology Immunology Laboratories, University of North Carolina Hospitals, North Carolina 27514, USA
    J Clin Microbiol 47:1231-3. 2009
    ....
  9. pmc Clinical outcomes with rapid detection of methicillin-resistant and methicillin-susceptible Staphylococcus aureus isolates from routine blood cultures
    Nicole C Nicolsen
    UNC Health Care, Department of Pharmacy, Chapel Hill, North Carolina, USA
    J Clin Microbiol 51:4126-9. 2013
    ..5 h). This study supports the hypothesis that rapid testing plays a role in antimicrobial stewardship by getting patients on targeted therapy faster. ..
  10. pmc Comparative evaluation of the Nanosphere Verigene RV+ assay and the Simplexa Flu A/B & RSV kit for detection of influenza and respiratory syncytial viruses
    Kevin Alby
    Clinical Microbiology Immunology Laboratories, UNC Health Care, Chapel Hill, North Carolina, USA
    J Clin Microbiol 51:352-3. 2013
    ..7% for influenza B virus, and 100% and 100% for respiratory syncytial virus (RSV), while the Simplexa test sensitivities and specificities were 82.8 and 99.7%, 76.2 and 100%, and 94.6 and 100%, respectively...
  11. doi request reprint Role of hospital surfaces in the transmission of emerging health care-associated pathogens: norovirus, Clostridium difficile, and Acinetobacter species
    David J Weber
    Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Am J Infect Control 38:S25-33. 2010
    ..Current hand hygiene guidelines and recommendations for surface cleaning/disinfection should be followed in managing outbreaks because of these emerging pathogens...
  12. ncbi request reprint Comparison of culture and 2 real-time polymerase chain reaction assays to detect group B Streptococcus during antepartum screening
    Jennifer S Goodrich
    Department of Pathology and Laboratory Medicine, University of North Carolina Hospitals, Chapel Hill, NC 27599, USA
    Diagn Microbiol Infect Dis 59:17-22. 2007
    ..In our hands, the sensitivity/specificity of the LC Strep B ASR was 100%/95.9%, and the BD-StrepB test was 92.5%/92.5% using culture as the gold standard...
  13. pmc Retrospective and prospective verification of the Cepheid Xpert influenza virus assay
    Elena B Popowitch
    UNC School of Medicine, Department of Pathology and Laboratory Medicine, Campus Box 7525, Chapel Hill, NC 27599 7525, USA
    J Clin Microbiol 49:3368-9. 2011
    ..Nasopharyngeal specimen sensitivities were 100% for seasonal influenza A/H1 virus and influenza A/H3 virus, 90% for influenza A/2009/H1N1 virus, and 95% for influenza B virus...
  14. pmc Comparison of matrix-assisted laser desorption ionization-time of flight (maldi-tof) mass spectrometry platforms for the identification of gram-negative rods from patients with cystic fibrosis
    Kevin Alby
    Clinical Microbiology Immunology Laboratories, UNC Health Care, Chapel Hill, North Carolina, USA
    J Clin Microbiol 51:3852-4. 2013
    ..Including those that underwent repeat testing, 96.6%, 90.1%, and 93.6% of isolates, respectively, had identifications that agreed with the previous identification. ..
  15. pmc Development of a treatment algorithm for streptococci and enterococci from positive blood cultures identified with the Verigene Gram-positive blood culture assay
    Kevin Alby
    Clinical Microbiology Immunology Laboratories, UNC Health Care, Chapel Hill, North Carolina, USA
    J Clin Microbiol 51:3869-71. 2013
    ..The overall concordance of the assay with culture was 89.7% (70/78 cultures), allowing for the development of a targeted treatment algorithm. ..
  16. pmc Should interferon gamma release assays become the standard method for screening patients for Mycobacterium tuberculosis infections in the United States?
    Thomas S Alexander
    University of North Carolina at Chapel Hill, Campus Box 7525, Chapel Hill, North Carolina 27599 7525, USA
    J Clin Microbiol 49:2086-92. 2011
    ....
  17. ncbi request reprint Are lower airway or throat cultures predictive of sinus bacteriology in cystic fibrosis?
    Marianne S Muhlebach
    Department of Pediatrics, University of North Carolina, 27599 7220, USA
    Pediatr Pulmonol 41:445-51. 2006
    ..We conclude that S. aureus is an important pathogen in pediatric CF sinusitis, and that BALF or oropharyngeal cultures are poor predictors for organisms present in the sinuses...
  18. pmc Comparison of the Biofire FilmArray RP, Genmark eSensor RVP, Luminex xTAG RVPv1, and Luminex xTAG RVP fast multiplex assays for detection of respiratory viruses
    Elena B Popowitch
    University of North Carolina Health Care System, Chapel Hill, North Carolina, USA
    J Clin Microbiol 51:1528-33. 2013
    ..Hands-on time and time to result were recorded and ease of use was assessed to generate a complete profile of each assay...
  19. pmc Ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with wild-type CMV in her plasma
    Hart B Moss
    Department of Ophthalmology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA
    J Clin Microbiol 50:1796-9. 2012
    ..Quantifying CMV from aqueous fluid was valuable for monitoring the clinical response and predicting resistance...
  20. pmc Evaluation of a non-invasive method to detect cytomegalovirus (CMV)-DNA in stool samples of patients with inflammatory bowel disease (IBD): a pilot study
    Hans H Herfarth
    Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina, Bioinformatics Bldg, CB 7080, Chapel Hill, NC, 27599, USA
    Dig Dis Sci 55:1053-8. 2010
    ..The aim of this pilot study was to investigate the diagnostic efficacy of quantitative polymerase chain reaction (PCR) to detect CMV DNA in stool samples of IBD patients...
  21. doi request reprint High-level human herpesvirus-6 viremia associated with onset of Stevens-Johnson syndrome: report of two cases
    Amanda F Peppercorn
    Department of Medicine, University of North Carolina, School of Medicine, Chapel Hill, USA
    J Burn Care Res 31:365-8. 2010
    ....
  22. doi request reprint Preventing healthcare-associated Aspergillus infections: review of recent CDC/HICPAC recommendations
    David J Weber
    Division of Infectious Diseases, UNC School of Medicine, Chapel Hill, NC 27599 7030, USA
    Med Mycol 47:S199-209. 2009
    ....
  23. pmc Comparison of Cepheid's analyte-specific reagents with BD directigen for detection of respiratory syncytial virus
    Jennifer S Goodrich
    University of North Carolina Hospitals, Clinical Microbiology Immunology Laboratory, Chapel Hill, NC, USA
    J Clin Microbiol 45:604-6. 2007
    ..The Directigen RSV assay resulted in a 23% false-negative rate, using PCR and chart review as the gold standard, indicating that rapid RSV PCR results would be advantageous...
  24. pmc Prevalence of vancomycin-resistant enterococcus in prenatal screening cultures
    Melissa B Miller
    Clinical Microbiology Immunology Laboratories, University of North Carolina Hospitals, Chapel Hill, North Carolina 27514, USA
    J Clin Microbiol 42:855-7. 2004
    ..Because of potential postpartum infections due to vancomycin-resistant enterococci (VRE) and the possible spread of vancomycin resistance, the prevalence of VRE in prenatal screening cultures was determined...
  25. pmc Laboratory aspects of management of chronic pulmonary infections in patients with cystic fibrosis
    Melissa B Miller
    Clinical Microbiology Immunology Laboratories, University of North Carolina Hospitals, University of North Carolina School of Medicine Chapel Hill, North Carolina 27514, USA
    J Clin Microbiol 41:4009-15. 2003
  26. ncbi request reprint CsrA and three redundant small RNAs regulate quorum sensing in Vibrio cholerae
    Derrick H Lenz
    Department of Molecular Biology, Howard Hughes Medical Institute, Princeton University, Princeton, NJ 08544 1014, USA
    Mol Microbiol 58:1186-202. 2005
    ..The VarS/VarA-CsrA/BCD system converges with the V. cholerae quorum-sensing systems to regulate the expression of the Qrr sRNAs, and thus, the entire quorum-sensing regulon...
  27. ncbi request reprint Parallel quorum sensing systems converge to regulate virulence in Vibrio cholerae
    Melissa B Miller
    Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA
    Cell 110:303-14. 2002
    ..cholerae. This quorum sensing apparatus is unusually complex, as it is composed of at least three parallel signaling channels. We show that in V. cholerae these communication systems converge to control virulence...
  28. pmc Quorum-sensing regulators control virulence gene expression in Vibrio cholerae
    Jun Zhu
    Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 99:3129-34. 2002
    ..Together these data suggest a role for quorum sensing in modulating expression of blocks of virulence genes in a reciprocal fashion in vivo...