M Miller

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi Genotypic variation in ATP-binding cassette transporter-1 (ABCA1) as contributors to the high and low high-density lipoprotein-cholesterol (HDL-C) phenotype
    Myrna Mantaring
    Department of Medicine, University of Maryland Medical Center and VA Maryland Health Care System, Baltimore, MD, USA
    Transl Res 149:205-10. 2007
  2. doi The effects of ezetimibe/simvastatin versus simvastatin monotherapy on platelet and inflammatory biomarkers in patients with metabolic syndrome
    Michael Miller
    Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Cardiology 125:74-7. 2013
  3. pmc Multiple splice defects in ABCA1 cause low HDL-C in a family with hypoalphalipoproteinemia and premature coronary disease
    Jeffrey Rhyne
    Department of Medicine, Cardiology Division, University Maryland Medical Center and Baltimore Veterans Affairs Medical Center, 22 South Greene Street, Baltimore, MD 21201, USA
    BMC Med Genet 10:1. 2009
  4. pmc Managing mixed dyslipidemia in special populations
    Michael Miller
    Department of Medicine, University of Maryland Hospital, Baltimore, MD, USA
    Prev Cardiol 13:78-83. 2010
  5. doi An emerging paradigm in atherosclerosis: focus on subclinical disease
    Michael Miller
    University of Maryland School of Medicine, Center for Preventive Cardiology, Division of Cardiology, University of Maryland Medical Center, Baltimore, MD 21201, USA
    Postgrad Med 121:49-59. 2009
  6. doi Relative atherogenicity and predictive value of non-high-density lipoprotein cholesterol for coronary heart disease
    Michael Miller
    Division of Cardiology, University of Maryland Medical Center, Baltimore, MD, USA
    Am J Cardiol 101:1003-8. 2008
  7. pmc The effect of mirthful laughter on the human cardiovascular system
    Michael Miller
    Department of Medicine, Division of Cardiology, University of Maryland Medical Center, Baltimore, MD 21201, USA
    Med Hypotheses 73:636-9. 2009
  8. pmc APOC3 promoter polymorphisms C-482T and T-455C are associated with the metabolic syndrome
    Michael Miller
    University of Maryland Hospital and Veterans Affairs Medical Center, Baltimore, Maryland, USA
    Arch Med Res 38:444-51. 2007
  9. pmc Comparative effects of three popular diets on lipids, endothelial function, and C-reactive protein during weight maintenance
    Michael Miller
    Divisionof Cardiology, University of Maryland Hospital, Room S3B06, 22 S Greene St, Baltimore, MD 21201, USA
    J Am Diet Assoc 109:713-7. 2009
  10. ncbi Divergent effects of joyful and anxiety-provoking music on endothelial vasoreactivity
    Michael Miller
    Division of Cardiology, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
    Psychosom Med 72:354-6. 2010

Research Grants

  1. MOLECULAR & CLINICAL EVALUATION OF LOW HDL SYNDROMES
    Michael Miller; Fiscal Year: 2000
  2. MOLECULAR & CLINICAL EVALUATION OF LOW HDL SYNDROMES
    Michael Miller; Fiscal Year: 2001
  3. MOLECULAR & CLINICAL EVALUATION OF LOW HDL SYNDROMES
    Michael Miller; Fiscal Year: 2002
  4. MOLECULAR & CLINICAL EVALUATION OF LOW HDL SYNDROMES
    Michael Miller; Fiscal Year: 2003
  5. NUTRITION ACADEMIC AWARD
    Michael Miller; Fiscal Year: 2004

Collaborators

Detail Information

Publications74

  1. ncbi Genotypic variation in ATP-binding cassette transporter-1 (ABCA1) as contributors to the high and low high-density lipoprotein-cholesterol (HDL-C) phenotype
    Myrna Mantaring
    Department of Medicine, University of Maryland Medical Center and VA Maryland Health Care System, Baltimore, MD, USA
    Transl Res 149:205-10. 2007
    ..0002, respectively) compared with lower HDL-C. These data reaffirm that rare mutations in ABCA1 are associated with low HDL-C. However, at least 1 ABCA1 polymorphism (eg, E1172D) may contribute to the high HDL-C phenotype...
  2. doi The effects of ezetimibe/simvastatin versus simvastatin monotherapy on platelet and inflammatory biomarkers in patients with metabolic syndrome
    Michael Miller
    Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Cardiology 125:74-7. 2013
    ..However, the clinical relevance of these findings await results of the IMPROVE-IT trial (Improved Reduction of Outcomes: Vytorin Efficacy International Trial)...
  3. pmc Multiple splice defects in ABCA1 cause low HDL-C in a family with hypoalphalipoproteinemia and premature coronary disease
    Jeffrey Rhyne
    Department of Medicine, Cardiology Division, University Maryland Medical Center and Baltimore Veterans Affairs Medical Center, 22 South Greene Street, Baltimore, MD 21201, USA
    BMC Med Genet 10:1. 2009
    ..We screened DNA from a 41 year-old male with low HDL-C (12 mg/dL [0.31 mmol/L]) and a family history of premature coronary heart disease (CHD) using polymerase chain reaction single-strand conformation polymorphism (SSCP) analysis...
  4. pmc Managing mixed dyslipidemia in special populations
    Michael Miller
    Department of Medicine, University of Maryland Hospital, Baltimore, MD, USA
    Prev Cardiol 13:78-83. 2010
    ..However, while combination therapy may successfully correct the associated dyslipidemia, it remains to be established whether the addition of a second agent improves coronary risk beyond statin monotherapy...
  5. doi An emerging paradigm in atherosclerosis: focus on subclinical disease
    Michael Miller
    University of Maryland School of Medicine, Center for Preventive Cardiology, Division of Cardiology, University of Maryland Medical Center, Baltimore, MD 21201, USA
    Postgrad Med 121:49-59. 2009
    ..The unique combination of benefits provided by statin therapy may have an application in treating subclinical atherosclerotic disease...
  6. doi Relative atherogenicity and predictive value of non-high-density lipoprotein cholesterol for coronary heart disease
    Michael Miller
    Division of Cardiology, University of Maryland Medical Center, Baltimore, MD, USA
    Am J Cardiol 101:1003-8. 2008
    ..In conclusion, non-HDL-C remains an important target of therapy for patients with elevated TGs, although its widespread adoption has yet to gain a foothold among health care professionals treating patients with dyslipidemia...
  7. pmc The effect of mirthful laughter on the human cardiovascular system
    Michael Miller
    Department of Medicine, Division of Cardiology, University of Maryland Medical Center, Baltimore, MD 21201, USA
    Med Hypotheses 73:636-9. 2009
    ..This article reviews the relevant physiology and comments on the potentially wider clinical implications in the integration of this process to improve vascular health...
  8. pmc APOC3 promoter polymorphisms C-482T and T-455C are associated with the metabolic syndrome
    Michael Miller
    University of Maryland Hospital and Veterans Affairs Medical Center, Baltimore, Maryland, USA
    Arch Med Res 38:444-51. 2007
    ..One candidate, APOC3, modulates lipid and lipoprotein metabolism and the promoter polymorphisms C-482T/T-455C are associated with loss of insulin downregulation...
  9. pmc Comparative effects of three popular diets on lipids, endothelial function, and C-reactive protein during weight maintenance
    Michael Miller
    Divisionof Cardiology, University of Maryland Hospital, Room S3B06, 22 S Greene St, Baltimore, MD 21201, USA
    J Am Diet Assoc 109:713-7. 2009
    ....
  10. ncbi Divergent effects of joyful and anxiety-provoking music on endothelial vasoreactivity
    Michael Miller
    Division of Cardiology, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
    Psychosom Med 72:354-6. 2010
    ..To evaluate the extent to which music may affect endothelial function. In previous research, a link between music and physiologic parameters such as heart rate and blood pressure has been observed...
  11. pmc Do mutations causing low HDL-C promote increased carotid intima-media thickness?
    Michael Miller
    University of Maryland Hospital and Veterans Affairs Medical Center, Baltimore, MD 21201, United States
    Clin Chim Acta 377:273-5. 2007
    ..Although observational data support an inverse relationship between high-density lipoprotein (HDL) cholesterol and coronary heart disease (CHD), genetic HDL deficiency states often do not correlate with premature CHD...
  12. pmc Impact of lowering triglycerides on raising HDL-C in hypertriglyceridemic and non-hypertriglyceridemic subjects
    Michael Miller
    Department of Medicine, University of Maryland Medical Center and Veterans Affairs Medical Center, Baltimore, MD, United States
    Int J Cardiol 119:192-5. 2007
    ..These data indicate that lowering TG is independently and inversely correlated with HDL-C, effects that are most pronounced in the absence of hypertriglyceridemia...
  13. pmc Dyslipidemia and cardiovascular risk: the importance of early prevention
    M Miller
    Center for Preventive Cardiology, Division of Cardiology, University of Maryland Medical Center, Baltimore, MD 21201, USA
    QJM 102:657-67. 2009
    ..Therefore, data from ongoing prospective studies will hopefully resolve this issue and facilitate identification of optimal strategies to augment CV risk reduction...
  14. ncbi Novel polypyrimidine variation (IVS46: del T -39...-46) in ABCA1 causes exon skipping and contributes to HDL cholesterol deficiency in a family with premature coronary disease
    Seung Ho Hong
    Department of Medicine, University of Maryland and Veterans Administration Medical Center, Baltimore, MD, USA
    Circ Res 93:1006-12. 2003
    ....
  15. ncbi ABCA1(Alabama): a novel variant associated with HDL deficiency and premature coronary artery disease
    Seung Ho Hong
    Section of Cardiology, Department of Medicine, University of Maryland and Veterans Administration Medical Center, 22 S Greene St, S3B06, Baltimore, MD 21201, USA
    Atherosclerosis 164:245-50. 2002
    ..These data confirm recent data that a single defective allele in ABCA1 may be associated with reduced HDL cholesterol and FHA...
  16. ncbi Apolipoprotein A-I(Zavalla) (Leu159-->Pro): HDL cholesterol deficiency in a kindred associated with premature coronary artery disease
    M Miller
    Department of Medicine, University of Maryland School of Medicine, Veterans Affairs Medical Center, Baltimore, USA
    Arterioscler Thromb Vasc Biol 18:1242-7. 1998
    ..In addition, it extends recent observations that HDL-C deficiency states may be more prone to the development of premature coronary artery disease when accompanied by additional cardiovascular risk factors...
  17. ncbi The role of triglycerides in cardiovascular risk
    Puneet Gandotra
    Department of Medicine, University of Maryland Hospital, Division of Cardiology, Room S3B06, 22 South Greene Street, Baltimore, MD 21201, USA
    Curr Cardiol Rep 10:505-11. 2008
    ..However, reducing very high triglycerides (ie, > 500 mg/dL) remains a sufficiently high priority in affected individuals...
  18. ncbi Effectiveness of high doses of simvastatin as monotherapy in mixed hyperlipidemia
    M Miller
    Division of Cardiology, University of Maryland Medical Center, Baltimore, USA
    Am J Cardiol 87:232-4, A9. 2001
    ..The highest dose of simvastatin also resulted in significant increases in high-density lipoprotein cholesterol (21%) with a comparable increase in large, protective high-density lipoprotein particles...
  19. pmc Malnutrition-inflammation modifies the relationship of cholesterol with cardiovascular disease
    Gabriel Contreras
    Department of Medicine, Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 360E, Miami, FL 33136, USA
    J Am Soc Nephrol 21:2131-42. 2010
    ..In the M-I group, the corresponding HRs did not vary significantly by cholesterol level. In conclusion, the presence of M-I modifies the risk relationship between cholesterol level and CVD in African Americans with hypertensive CKD...
  20. ncbi The two novel CETP mutations Gln87X and Gln165X in a compound heterozygous state are associated with marked hyperalphalipoproteinemia and absence of significant coronary artery disease
    Jeffrey Rhyne
    University of Maryland and Veterans Affairs Medical Center, Baltimore, MD, USA
    J Mol Med (Berl) 84:647-50. 2006
    ..However, it remains unclear as to whether the relative lack of coronary atherosclerosis was the direct consequence of CETP deficiency and/or the lack of traditional CAD risk factors...
  21. ncbi Optimal treatment of dyslipidemia in high-risk patients: intensive statin treatment or combination therapy?
    Michael Miller
    University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Prev Cardiol 10:31-5. 2007
    ..Nonetheless, for residual elevation in triglycerides and/or reduced high-density lipoprotein cholesterol, adding a second agent (eg, fenofibrate, niacin) is a reasonable option...
  22. pmc A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection
    Toni I Pollin
    Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Science 322:1702-5. 2008
    ..Subclinical atherosclerosis, as measured by coronary artery calcification, was less common in carriers than noncarriers, which suggests that lifelong deficiency of apoC-III has a cardioprotective effect...
  23. doi Impact of triglyceride levels beyond low-density lipoprotein cholesterol after acute coronary syndrome in the PROVE IT-TIMI 22 trial
    Michael Miller
    Division of Cardiology, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
    J Am Coll Cardiol 51:724-30. 2008
    ..The purpose of this study was to assess the impact of on-treatment triglycerides (TG) on coronary heart disease (CHD) risk after an acute coronary syndrome (ACS)...
  24. ncbi High attributable risk of elevated C-reactive protein level to conventional coronary heart disease risk factors: the Third National Health and Nutrition Examination Survey
    Michael Miller
    Department of Medicine, University of Maryland School of Medicine, Baltimore, USA
    Arch Intern Med 165:2063-8. 2005
    ..However, the extent to which high CRP levels (>3 mg/L) may be attributable to high cholesterol levels and other CHD risk factors has not been well defined...
  25. ncbi Baseline disease activity, hyperlipidemia, and hypertension are predictive factors for ischemic stroke and stroke severity in systemic lupus erythematosus
    Jamal Mikdashi
    Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine, 10 South Pine Street, Suite 834, Baltimore, MD 21201, USA
    Stroke 38:281-5. 2007
    ..To determine factors associated with ischemic stroke and stroke severity in patients with systemic lupus erythematosus...
  26. ncbi Bezafibrate reduces the incidence of type 2 diabetes mellitus in patients with obesity
    Michael Miller
    University of Maryland Medical Center, Baltimore, MD, USA
    Nat Clin Pract Endocrinol Metab 2:198-9. 2006
  27. ncbi Update on the role of triglycerides as a risk factor for coronary heart disease
    Michael Miller
    Department of Medicine, University of Maryland School of Medicine, 655 West Baltimore Street, Baltimore, MD 21201, USA
    Curr Atheroscler Rep 4:414-8. 2002
    ..However, an important yet unanswered question is whether decreasing triglycerides beyond low-density lipoprotein cholesterol lowering contributes significantly to additional coronary heart disease event reduction...
  28. ncbi Raising an isolated low HDL-C level: why, how, and when?
    Michael Miller
    Center for Preventive Cardiology, Department of Medicine and Epidemiology, University of Maryland Medical Center, Baltimore 21201, USA
    Cleve Clin J Med 70:553-60. 2003
    ..While no current therapy is optimal, many can yield modest increases that translate into reduced risk for CHD events...
  29. ncbi Genetics of HDL regulation in humans
    Michael Miller
    Departments of Medicine and Epidemiology, Veterans Affairs and University of Maryland Medical Center, Baltimore, MD 21201, USA
    Curr Opin Lipidol 14:273-9. 2003
    ..To review gene regulation of HDL-cholesterol and discuss molecular abnormalities in HDL candidate genes that may lead to human pathologic states...
  30. ncbi Niacin as a component of combination therapy for dyslipidemia
    Michael Miller
    Center for Preventive Cardiology, University of Maryland Medical Center, Baltimore 21201, USA
    Mayo Clin Proc 78:735-42. 2003
    ..Adding niacin to lipid-lowering regimens is a valuable option for physicians treating patients with dyslipidemia and should be considered in appropriate patients...
  31. ncbi Effect of desirable fasting triglycerides on the postprandial response to dietary fat
    Michael Miller
    Division of Cardiology, Department of Medicine, Veterans Affairs Medical Center University of Maryland, Baltimore, MD 21201, USA
    J Investig Med 51:50-5. 2003
    ..The National Cholesterol Education Program (NCEP) recently revised the "desirable" fasting triglyceride (TG) to < 150 mg/dL, and levels exceeding 200 mg/dL are defined as "high."..
  32. ncbi Genetic determinants of low high-density lipoprotein cholesterol
    Michael Miller
    Department of Medicine, University of Maryland Hospital and Veterans Affairs Medical Center, Baltimore, Maryland, USA
    Curr Opin Cardiol 19:380-4. 2004
    ..This review summarizes recent data involving HDL regulatory genes and their role in atherothrombosis...
  33. ncbi Novel ABCA1 compound variant associated with HDL cholesterol deficiency
    Seung Ho Hong
    Department of Medicine, University of Maryland and Veterans Administration Medical Center, 22 S Greene St, S3B06 Baltimore 21201, USA
    Biochim Biophys Acta 1587:60-4. 2002
    ..Direct sequencing of all coding regions and splice site junctions of other HDL candidate genes revealed no additional mutations, indicating that combined defective ABCA1 alleles may result in familial HDL deficiency...
  34. ncbi The effect of simvastatin on triglyceride-rich lipoproteins in patients with type 2 diabetic dyslipidemia: a SILHOUETTE trial sub-study
    M Miller
    University of Maryland Medical Center, Baltimore, Maryland, USA
    Curr Med Res Opin 22:343-50. 2006
    ..To determine if simvastatin effectively decreases the elevated levels of triglyceride (TG), TG-rich lipoproteins, and small, dense LDL particles, which are characteristic of diabetic dyslipidemia...
  35. ncbi Serum metalloproteinase leukolysin (MMP-25/MT-6): a potential metabolic marker for atopy-associated inflammation
    M N Blumenthal
    Department of Medicine, The Asthma and Allergy Center, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    Clin Exp Allergy 40:859-66. 2010
    ..Leukolysin is a novel matrix metalloproteinase (MMP-25/MT-6) released mainly by granulocytic cells, primarily neutrophils, which are implicated in chronic airways inflammation...
  36. ncbi Normal triglyceride levels and coronary artery disease events: the Baltimore Coronary Observational Long-Term Study
    M Miller
    Division of Cardiology, University of Maryland School of Medicine, Baltimore 21201 1595, USA
    J Am Coll Cardiol 31:1252-7. 1998
    ..This study sought to evaluate long-term predictors of coronary events in men and women with arteriographically defined coronary artery disease (CAD)...
  37. ncbi Prevalence of the APOC3 promoter polymorphisms T-455C and C-482T in Asian-Indians
    M Miller
    Division of Cardiology, University of Maryland Medical Center, Baltimore, USA
    Am J Cardiol 87:220-1, A8. 2001
    ..Polymorphisms in the APOC3 promoter (-455 T/C and -482 C/T) were frequently encountered in young Asian-Indians and they correlated with reduced concentrations of apolipoprotein A-I...
  38. ncbi Lecithin: cholesterol acyltransferase deficiency: identification of two defective alleles in fibroblast cDNA
    M Miller
    Department of Medicine, Veterans Administration Medical Center, Baltimore, MD 21201, USA
    J Lipid Res 36:931-8. 1995
    ..Expression studies of mutant LCAT cDNA confirmed the virtual absence of LCAT activity in transfected COS-1 cells. The molecular defect in a young male with complete LCAT deficiency has been identified using fibroblast cDNA...
  39. ncbi Sex bias and underutilization of lipid-lowering therapy in patients with coronary artery disease at academic medical centers in the United States and Canada. Prospective Randomized Evaluation of the Vascular Effects of Norvasc Trial (PREVENT) Investigator
    M Miller
    Department of Medicine, University of Maryland Medical Center, Baltimore, USA
    Arch Intern Med 160:343-7. 2000
    ..However, limited information is available assessing the extent to which these medications are prescribed in academic medical centers...
  40. ncbi Alternative splicing in lecithin:cholesterol acyltransferase mRNA: an evolutionary paradigm in humans and great apes
    M Miller
    Department of Medicine, Veterans Affairs Medical Center and University of Maryland Medical Center, Baltimore 21201, USA
    Gene 190:309-13. 1997
    ..These results demonstrate that alternative splicing of LCAT mRNA is variant among primates and suggest a potential role of Alu elements in the evolutionary diversity of proteins...
  41. ncbi Lack of association between increased carotid intima-media thickening and decreased HDL-cholesterol in a family with a novel ABCA1 variant, G2265T
    Seung Ho Hong
    Department of Medicine, University of Maryland and Veterans Administration Medical Center, Baltimore, MD 21201, USA
    Clin Chem 48:2066-70. 2002
    ..Although these data extend previous observations that a single defective ABCA1 allele may lead to decreased HDL-C, associated evidence of early atherosclerosis was not confirmed...
  42. ncbi Low high-density lipoprotein cholesterol: an important consideration in coronary heart disease risk assessment
    Farhan Majeed
    Department of Medicine, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
    Curr Opin Endocrinol Diabetes Obes 15:175-81. 2008
    ..Other aims are to explore the mechanisms underlying the reported cardioprotective effects of high-density lipoprotein and to evaluate therapeutic modalities to increase high-density lipoprotein levels and functionality...
  43. ncbi Effectiveness of simvastatin therapy in raising HDL-C in patients with type 2 diabetes and low HDL-C
    Michael Miller
    University of Maryland Medical Center, Baltimore, MD, USA
    Curr Med Res Opin 20:1087-94. 2004
    ....
  44. ncbi Hyponatremia: age-related risk factors and therapy decisions
    M Miller
    Levindale Hebrew Geriatric Center and Hospital, Baltimore, USA
    Geriatrics 53:32-3, 37-8, 41-2 passim. 1998
    ..Awareness of these risk factors allows the physician to anticipate the impact of illnesses and drugs on volume and electrolyte status of the older patient and to implement a rational approach to therapeutic intervention and management...
  45. ncbi Current perspectives on the management of hypertriglyceridemia
    M Miller
    University of Maryland Medical System, Baltimore, MD, USA
    Am Heart J 140:232-40. 2000
    ..There are considerable data that lowering LDL cholesterol reduces cardiovascular events. However, the importance of triglyceride lowering remains elusive...
  46. pmc Family-based association of YWHAH in psychotic bipolar disorder
    Deepak Grover
    Department of Psychiatry, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA
    Am J Med Genet B Neuropsychiatr Genet 150:977-83. 2009
    ....
  47. ncbi A novel TC deletion resulting in Pro(260)-->Stop in the human LCAT gene is associated with a dominant effect on HDL-cholesterol
    A Kasid
    Department of Medicine, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    Atherosclerosis 156:127-32. 2001
    ....
  48. pmc Phase i/ii trial of the pharmacokinetics, safety, and antiretroviral activity of tenofovir disoproxil fumarate in human immunodeficiency virus-infected adults
    P Barditch-Crovo
    The Johns Hopkins University School of Medicine, 600 N Wolfe St, Baltimore, MD 21287, USA
    Antimicrob Agents Chemother 45:2733-9. 2001
    ..No patients developed detectable sequence changes in the reverse transcriptase gene...
  49. ncbi Effect of statins on platelet PAR-1 thrombin receptor in patients with the metabolic syndrome (from the PAR-1 inhibition by statins [PARIS] study)
    Victor L Serebruany
    HeartDrug Research Laboratories, Johns Hopkins University, Towson, MD, USA
    Am J Cardiol 97:1332-6. 2006
    ..These observational data offer a plausible mechanism for the recently demonstrated pleiotropic effects of statins that may contribute to early clinical benefit...
  50. ncbi Effects of simvastatin (40 and 80 mg) on highly sensitive C-reactive protein in patients with combined hyperlipidemia
    Michael Miller
    University of Maryland and Veterans Affairs Medical Center, Baltimore, Maryland, USA
    Am J Cardiol 89:468-9. 2002
  51. ncbi Exercise-induced hypertension, endothelial dysfunction, and coronary artery disease in a marathon runner
    Radha Goel
    Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA
    Am J Cardiol 99:743-4. 2007
    ..In conclusion, vigorous aerobic activity in susceptible individuals may promote oxidative stress and coronary atherosclerosis...
  52. ncbi The role of the phospholipid sphingomyelin in heart disease
    Subroto Chatterjee
    Department of Pediatrics, Johns Hopkins University, Baltimore, MD 21205, USA
    Curr Opin Investig Drugs 7:219-28. 2006
    ..Further studies of the molecular and pathobiological basis of these phospholipids may facilitate advances in the discovery of drugs with which to mitigate diseases that may result from an elevation in SM and its metabolites...
  53. pmc Pattern separation in the human hippocampal CA3 and dentate gyrus
    Arnold Bakker
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD, USA
    Science 319:1640-2. 2008
    ..These results provide compelling evidence of a key role of the human CA3/dentate gyrus in pattern separation...
  54. pmc Research pointers: Platelet responsiveness to aspirin in patients with hyperlipidaemia
    Maribeth Friend
    Department of Medical and Research Technology and Medicine, University of Maryland Medical Center, Baltimore, MD 21201, USA
    BMJ 326:82-3. 2003
  55. ncbi Intensive versus moderate lipid lowering with statins after acute coronary syndromes
    Michael Miller
    N Engl J Med 351:714-7; author reply 714-7. 2004
  56. ncbi Lipid levels in the post-acute coronary syndrome setting: destabilizing another myth?
    Michael Miller
    J Am Coll Cardiol 51:1446-7. 2008
  57. ncbi High prevalence of C-reactive protein elevation with normal triglycerides (100-149 mg/dL): are triglyceride levels below 100 mg/dL more optimal in coronary heart disease risk assessment?
    Irfan Ahmad
    School of Public Health, Yale University, New Haven, Connecticut, USA
    Am J Med Sci 329:173-7. 2005
    ..The National Cholesterol Education Program defines a fasting triglyceride level below 150 mg/dL as normal. However, observational data suggest that triglyceride levels above 100 mg/dL may predict coronary heart disease (CHD) events...
  58. ncbi Role of LCAT in HDL remodeling: investigation of LCAT deficiency states
    Bela F Asztalos
    Lipid Metabolism Laboratory, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
    J Lipid Res 48:592-9. 2007
    ....
  59. ncbi Hypertriglyceridemia and cardiovascular risk reduction
    Terry A Jacobson
    Office of Health Promotion and Disease Prevention, Emory University, Atlanta, GA 30303, USA
    Clin Ther 29:763-77. 2007
    ..There is evidence that elevated TG levels may be a significant independent risk factor for coronary heart disease (CHD), particularly in women...
  60. pmc Comparative selection of the K65R and M184V/I mutations in human immunodeficiency virus type 1-infected patients enrolled in a trial of first-line triple-nucleoside analog therapy (Tonus IMEA 021)
    Christophe Delaunay
    Laboratoire de Virologie, Hopital Bichat Claude Bernard, Paris, France
    J Virol 79:9572-8. 2005
    ..This convergent genetic pathway to resistance, associated with lower antiretroviral potency, may explain the high selection rate of these mutations in this trial...
  61. ncbi [Angiosarcoma of the liver as a rare cause of rapidly progressive liver failure]
    Alisan Kahraman
    Klinik für Gastroenterologie und Hepatologie, Universitatsklinikum Essen, Hufelandstrasse 55, 45122 Essen
    Med Klin (Munich) 101:746-50. 2006
    ..Angiosarcoma of the liver is a rare, highly malignant and sometimes diffusely infiltrating vessel tumor with rapid progression and poor prognosis...
  62. ncbi Comprehensive linkage and linkage heterogeneity analysis of 4344 sibling pairs affected with hypertension from the Family Blood Pressure Program
    Tiffany A Greenwood
    Polymorphism Research Laboratory, Department of Psychiatry, University of California, San Diego, La Jolla, California 92093 0603, USA
    Genet Epidemiol 31:195-210. 2007
    ..Ultimately our results suggest that evidence for linkage heterogeneity can only be detected with large sample sizes, such as the FBPP, which is consistent with theoretical sample size calculations...
  63. pmc Direct care workers in the National Drug Abuse Treatment Clinical Trials Network: characteristics, opinions, and beliefs
    Dennis McCarty
    Department of Public Health and Preventive Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA
    Psychiatr Serv 58:181-90. 2007
    ..Individuals with direct care responsibilities in 348 drug abuse treatment units were surveyed to obtain a description of the workforce and to assess support for evidence-based therapies...
  64. ncbi High efficiency transgene segregation in co-transformed maize plants using an Agrobacterium tumefaciens 2 T-DNA binary system
    Michael Miller
    Pioneer Hi Bred International Inc, Johnston, Iowa 50131, USA
    Transgenic Res 11:381-96. 2002
    ..A high efficiency system to segregate transgenes in co-transformed maize plants has now been demonstrated...
  65. pmc Resistance to chronic wasting disease in transgenic mice expressing a naturally occurring allelic variant of deer prion protein
    Kimberly Meade-White
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases NIH, 903 South Fourth Street, Hamilton, MT 59840, USA
    J Virol 81:4533-9. 2007
    ....
  66. pmc Organizational Readiness for Change and opinions toward treatment innovations
    Bret E Fuller
    Oregon Health and Science University, Portland, OR 97239, USA
    J Subst Abuse Treat 33:183-92. 2007
    ..The analysis provides evidence of the ORC's utility in assessing agency strengths and needs during the implementation of evidence-based practices...
  67. ncbi Long-term user perceptions of an implanted neuroprosthesis for exercise, standing, and transfers after spinal cord injury
    Sanjeev Agarwal
    Department of Orthopaedic Surgery, Case Western Reserve University School of Medicine, Cleveland, OH, USA
    J Rehabil Res Dev 40:241-52. 2003
    ..The implanted standing neuroprosthesis appears to be a clinically acceptable and effective means of providing the ability to exercise, stand, and transfer to selected individuals with paraplegia or low tetraplegia...
  68. ncbi Ethyl glucuronide: a biomarker to identify alcohol use by health professionals recovering from substance use disorders
    Gregory E Skipper
    Alabama Physician Health Program and University of Alabama Birmingham School of Medicine, Montgomery, Alabama, USA
    Alcohol Alcohol 39:445-9. 2004
    ..Ethyl glucuronide (EtG), a direct metabolite of alcohol, offers an extended window for assessment of drinking status (up to 5 days). Our aim was to assess the potential value of EtG testing in abstinence-based monitoring programs...
  69. ncbi Semi-automated basal ganglia segmentation using large deformation diffeomorphic metric mapping
    Ali Khan
    School of Engineering Science, Simon Fraser University, 8888 University Drive, Burnaby BC, V5A 1S6, Canada
    Med Image Comput Comput Assist Interv 8:238-45. 2005
    ..Our accuracy is compared against gold-standard manual segmentations and various automated segmentation tools through the use of several error metrics...
  70. ncbi Clinically validated genotype analysis: guiding principles and statistical concerns
    Francoise Brun-Vezinet
    Hospital Bichat Claude Bernard, Paris, France
    Antivir Ther 9:465-78. 2004
    ....
  71. ncbi A 19-month-old girl with congestive heart failure, hypertension, and coronary artery dilatations. Interview by Robert Listernick
    Denise Goodman
    Pediatr Ann 34:14, 16, 17-9. 2005
  72. ncbi Targeting glucose in acute myocardial infarction: has glucose, insulin, and potassium infusion missed the target?
    Ajay Chaudhuri
    Department of Endocrinology, State University at New York at Buffalo and Kaleida Health, Buffalo, New York, USA
    Diabetes Care 30:3026-8. 2007
  73. ncbi Angiographic diagnosis and endovascular management of nonvariceal gastrointestinal hemorrhage
    Michael Miller
    Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA
    Gastroenterol Clin North Am 34:735-52. 2005
    ..To that end, there is a great need for scientific data regarding the safety and efficacy of transcatheter therapy for upper and lower GI bleeding...
  74. ncbi Omega-3 fatty acids and coronary heart disease risk: clinical and mechanistic perspectives
    William S Harris
    Nutrition and Metabolic Disease Research, Sanford Research USD, Sanford School of Medicine, University of South Dakota, Sioux Falls, SD 57105, USA
    Atherosclerosis 197:12-24. 2008
    ..Our focus is to review the potential mechanisms by which these fatty acids reduce cardiovascular disease risk...

Research Grants5

  1. MOLECULAR & CLINICAL EVALUATION OF LOW HDL SYNDROMES
    Michael Miller; Fiscal Year: 2000
    ..Further understanding of the molecular basis of isolated low HDL-C and its potential clinical sequelae (e.g., CAD), may therefore aid in the development of therapeutic strategies to effectively treat this disorder. ..
  2. MOLECULAR & CLINICAL EVALUATION OF LOW HDL SYNDROMES
    Michael Miller; Fiscal Year: 2001
    ..Further understanding of the molecular basis of isolated low HDL-C and its potential clinical sequelae (e.g., CAD), may therefore aid in the development of therapeutic strategies to effectively treat this disorder. ..
  3. MOLECULAR & CLINICAL EVALUATION OF LOW HDL SYNDROMES
    Michael Miller; Fiscal Year: 2002
    ..Further understanding of the molecular basis of isolated low HDL-C and its potential clinical sequelae (e.g., CAD), may therefore aid in the development of therapeutic strategies to effectively treat this disorder. ..
  4. MOLECULAR & CLINICAL EVALUATION OF LOW HDL SYNDROMES
    Michael Miller; Fiscal Year: 2003
    ..Further understanding of the molecular basis of isolated low HDL-C and its potential clinical sequelae (e.g., CAD), may therefore aid in the development of therapeutic strategies to effectively treat this disorder. ..
  5. NUTRITION ACADEMIC AWARD
    Michael Miller; Fiscal Year: 2004
    ..Compliance with ATP II and JNC VI recommendations will also be assessed. In addition, medical students' diets and blood lipid levels will be assessed and tracked. ..