JOSHUA WILLIAM MILLER

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Homocysteine, cysteine, and risk of incident colorectal cancer in the Women's Health Initiative observational cohort
    Joshua W Miller
    Department of Medical Pathology and Laboratory Medicine, University of California, Davis, Davis, CA 95817, USA
    Am J Clin Nutr 97:827-34. 2013
  2. ncbi request reprint Homocysteine and cognitive function in the Sacramento Area Latino Study on Aging
    Joshua W Miller
    Department of Medical Pathology, School of Medicine, University of California, Davis, USA
    Am J Clin Nutr 78:441-7. 2003
  3. ncbi request reprint Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status
    J W Miller
    Vitamin Bioavailability Lab, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    Neurology 60:1125-9. 2003
  4. ncbi request reprint Transcobalamin II 775G>C polymorphism and indices of vitamin B12 status in healthy older adults
    Joshua W Miller
    Department of Medical Pathology, School of Medicine, University of California, Davis, CA 95817, USA
    Blood 100:718-20. 2002
  5. ncbi request reprint Homocysteine, vitamin B6, and vascular disease in AD patients
    J W Miller
    Department of Medical Pathology, University of California, Davis, School of Medicine, Sacramento 95817, USA
    Neurology 58:1471-5. 2002
  6. ncbi request reprint Does lowering plasma homocysteine reduce vascular disease risk?
    J W Miller
    University of California, Davis, Medical Center, Department of Medical Pathology, Sacramento 95817, USA
    Nutr Rev 59:242-4. 2001
  7. pmc Transcobalamin C776G genotype modifies the association between vitamin B12 and homocysteine in older Hispanics
    M G Garrod
    USDA, ARS Western Human Nutrition Research Center, Davis, CA 95817, USA
    Eur J Clin Nutr 64:503-9. 2010
  8. ncbi request reprint Low erythrocyte folate, but not plasma vitamin B-12 or homocysteine,is associated with dementia in elderly Latinos
    A K Campbell
    University of California, Davis, CA, USA
    J Nutr Health Aging 9:39-43. 2005
  9. ncbi request reprint Oxidative damage caused by free radicals produced during catecholamine autoxidation: protective effects of O-methylation and melatonin
    J W Miller
    Vitamin Bioavailability Laboratory, Jean Mayer, USDA Human Nutrition Research Center on Aging, Tufts University, USA
    Free Radic Biol Med 21:241-9. 1996
  10. ncbi request reprint Effect of vitamin B-6 deficiency on fasting plasma homocysteine concentrations
    J W Miller
    USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111
    Am J Clin Nutr 55:1154-60. 1992

Research Grants

Detail Information

Publications10

  1. pmc Homocysteine, cysteine, and risk of incident colorectal cancer in the Women's Health Initiative observational cohort
    Joshua W Miller
    Department of Medical Pathology and Laboratory Medicine, University of California, Davis, Davis, CA 95817, USA
    Am J Clin Nutr 97:827-34. 2013
    ..Hyperhomocysteinemia is associated with inflammation and may be a risk marker for CRC. Cysteine is a metabolic product of homocysteine and a precursor of the antioxidant glutathione. It is unknown whether cysteine is associated with CRC...
  2. ncbi request reprint Homocysteine and cognitive function in the Sacramento Area Latino Study on Aging
    Joshua W Miller
    Department of Medical Pathology, School of Medicine, University of California, Davis, USA
    Am J Clin Nutr 78:441-7. 2003
    ....
  3. ncbi request reprint Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status
    J W Miller
    Vitamin Bioavailability Lab, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
    Neurology 60:1125-9. 2003
    ..This effect of L-dopa on plasma homocysteine is accentuated under conditions of impaired homocysteine metabolism such as folate deficiency...
  4. ncbi request reprint Transcobalamin II 775G>C polymorphism and indices of vitamin B12 status in healthy older adults
    Joshua W Miller
    Department of Medical Pathology, School of Medicine, University of California, Davis, CA 95817, USA
    Blood 100:718-20. 2002
    ..02). The PP genotype may be more efficient in delivering B12 to tissues, resulting in enhanced B12 functional status. TCII genotype may thus influence susceptibility to B12 deficiency...
  5. ncbi request reprint Homocysteine, vitamin B6, and vascular disease in AD patients
    J W Miller
    Department of Medical Pathology, University of California, Davis, School of Medicine, Sacramento 95817, USA
    Neurology 58:1471-5. 2002
    ..Patients with AD tend to have unexplained elevations of homocysteine concentrations vs healthy control subjects. Vitamin B(6) status, a potential determinant of plasma homocysteine, has not been characterized in patients with AD...
  6. ncbi request reprint Does lowering plasma homocysteine reduce vascular disease risk?
    J W Miller
    University of California, Davis, Medical Center, Department of Medical Pathology, Sacramento 95817, USA
    Nutr Rev 59:242-4. 2001
    ..Questions about study design and sample size, however, suggest that this conclusion may be premature...
  7. pmc Transcobalamin C776G genotype modifies the association between vitamin B12 and homocysteine in older Hispanics
    M G Garrod
    USDA, ARS Western Human Nutrition Research Center, Davis, CA 95817, USA
    Eur J Clin Nutr 64:503-9. 2010
    ..A common polymorphism, C776G, in the plasma B12 transport protein transcobalamin (TC), encodes for either proline or arginine at codon 259. This polymorphism may affect the affinity of TC for B12 and subsequent delivery of B12 to tissues...
  8. ncbi request reprint Low erythrocyte folate, but not plasma vitamin B-12 or homocysteine,is associated with dementia in elderly Latinos
    A K Campbell
    University of California, Davis, CA, USA
    J Nutr Health Aging 9:39-43. 2005
    ..We conclude that folate status is associated with dementia but that more research is needed on the relationship between vitaminB-12 status, Hcy and cognitive function to explore possible associations with these parameters...
  9. ncbi request reprint Oxidative damage caused by free radicals produced during catecholamine autoxidation: protective effects of O-methylation and melatonin
    J W Miller
    Vitamin Bioavailability Laboratory, Jean Mayer, USDA Human Nutrition Research Center on Aging, Tufts University, USA
    Free Radic Biol Med 21:241-9. 1996
    ..These findings suggest that O-methylation and melatonin may be important components of the brain's antioxidant defenses against catecholamine autoxidation and may protect against consequent dopaminergic neurodegeneration...
  10. ncbi request reprint Effect of vitamin B-6 deficiency on fasting plasma homocysteine concentrations
    J W Miller
    USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111
    Am J Clin Nutr 55:1154-60. 1992
    ..It is concluded that fasting plasma homocysteine concentrations are not initially elevated in vitamin B-6 deficiency and therefore fasting plasma homocysteine concentrations are not a good indicator of vitamin B-6 status...

Research Grants3

  1. B12 Absorption, Kinetics and Transcobalamin Genotype
    Joshua Miller; Fiscal Year: 2004
    ..This novel method would ultimately replace the Schilling test, the current gold standard, but flawed and cumbersome method for clinical assessment of B 12 absorptive capacity. ..
  2. Folate, DNA Methylation and Breast Tumorigenesis
    Joshua Miller; Fiscal Year: 2007
    ....