Research Topics
Species | John W MillerSummaryAffiliation: University of Washington Country: USA Publications
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Publications
The experience of earthquakes by patients with epileptic and psychogenic nonepileptic seizuresNathaniel F Watson
Regional Epilepsy Center, Department of Neurology, University of Washington, Seattle, Washington 98104, USA
Epilepsia 43:317-20. 2002..This indicates these two experiences are similar and provides a glimpse into the subjective experience of a seizure for those who have never had one but have experienced an earthquake...- Atypical speech is rare in individuals with normal developmental historiesJ W Miller
Regional Epilepsy Center, University of Washington School of Medicine, Seattle, WA 98104 2499, USA
Neurology 60:1042-4. 2003..All 50 patients had left hemispheric speech on IAP. Atypical speech lateralization is rare unless there is also a positive neurologic history... - Gender differences in handedness and speech lateralization related to early neurologic insultsJohn W Miller
The Regional Epilepsy Center, Harborview Medical Center, Department of Neurology, University of Washington School of Medicine, Seattle, WA, USA
Neurology 65:1974-5. 2005..003) as was left-handedness (26 vs 10, p = 0.004). This could be attributed to greater plasticity or functional symmetry in females... - Ictal localization by source analysis of infraslow activity in DC-coupled scalp EEG recordingsJohn W Miller
Regional Epilepsy Center, Department of Neurology, University of Washington Regional Epilepsy Center, Box 359745, 325 Ninth Ave, Seattle, WA 98104, USA
Neuroimage 35:583-97. 2007..The value of this method is increased by source analysis tools that reveal localized changes more clearly than direct visual inspection... 
Is it necessary to define the ictal onset zone with EEG prior to performing resective epilepsy surgery?John W Miller
Department of Neurology and Neurological Surgery and University of Washington Regional Epilepsy Center, University of Washington, School of Medicine, Seattle, WA 98104, USA
Epilepsy Behav 20:178-81. 2011..To improve outcomes, improvements in both neuroimaging and EEG techniques are needed...
Cortical stimulation mapping and Wada results demonstrate a normal variant of right hemisphere language organizationDaniel L Drane
Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, USA
Epilepsia 53:1790-8. 2012..Furthermore, these data confirm the Wada test findings of atypical dominance...- Progression from frontal-parietal to mesial-temporal epilepsy after fluid percussion injury in the ratRAIMONDO D'AMBROSIO
Department of Neurological Surgery, Center on Human Development and Disability, University of Washington, School of Medicine, Harborview Medical Center, Box 359915, 325 Ninth Avenue, Seattle, WA 98104, USA
Brain 128:174-88. 2005..These observations establish numerous similarities between FPI-induced and human PTE and further validate it as a clinically relevant model of PTE... - Functional definition of seizure provides new insight into post-traumatic epileptogenesisRAIMONDO D'AMBROSIO
Department of Neurological Surgery, School of Medicine, University of Washington Harborview Medical Center, 325 Ninth Avenue, Seattle, WA 98104, USA
Brain 132:2805-21. 2009.... - Long-term outcome of extratemporal resection in posttraumatic epilepsyShahin Hakimian
Department of Neurology, University of Washington, USA
Neurosurg Focus 32:E10. 2012..The authors investigated and characterized the long-term outcome and patient factors associated with outcome in this population... - Comparing noninvasive dense array and intracranial electroencephalography for localization of seizuresMark D Holmes
Regional Epilepsy Center, Department of Neurology, University of Washington, Seattle, Washington 98104, USA
Neurosurgery 66:354-62. 2010.... - A comparison of epilepsy self-management needs: provider and patient perspectivesErica K Johnson
Department of Human Services and Rehabilitation, Western Washington University and Health Promotion Research Center, University of Washington, Seattle, WA, USA
Epilepsy Behav 25:150-5. 2012..Implications and explanations are offered as points for consideration in self-management program development... - Category-specific naming and recognition deficits in temporal lobe epilepsy surgical patientsDaniel L Drane
Department of Neurology, University of Washington, Seattle, WA, United States UW Regional Epilepsy Center, Harborview Medical Center, Seattle, WA, United States
Neuropsychologia 46:1242-55. 2008.... - Category-specific recognition and naming deficits following resection of a right anterior temporal lobe tumor in a patient with atypical language lateralizationDaniel L Drane
Department of Neurology, University of Washington, Seattle, WA, USA
Cortex 45:630-40. 2009..As various object categories appear to have different neuroanatomical representations in the TLs, we discuss the possible benefits of sampling a wider array of objects during cortical stimulation mapping of language... - Mild passive focal cooling prevents epileptic seizures after head injury in ratsRAIMONDO D'AMBROSIO
Department of Neurological Surgery, University of Washington, Seattle, WA, USA
Ann Neurol 73:199-209. 2013..We examined the effect of mild passive focal cooling of the perilesional neocortex on the development of neocortical epileptic seizures after head injury in the rat... - Managing epilepsy well: self-management needs assessmentRobert T Fraser
Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA
Epilepsy Behav 20:291-8. 2011..Emotional self-management and cognitive compensatory strategies require special emphasis given the challenges of a large subgroup... - Ictal localization by invasive recording of infraslow activity with DC-coupled amplifiersWonsuk Kim
School of Medicine, Departments of Neurology and Neurosurgery, University of Washington, Seattle, Washington, USA
J Clin Neurophysiol 26:135-44. 2009..The high voltage of infraslow activity may explain why infraslow activity localizes seizures better than conventional EEG with scalp recordings... - Determination of language dominance with near-infrared spectroscopy: comparison with the intracarotid amobarbital procedureNathaniel F Watson
Department of Neurology, University of Washington Regional Epilepsy Center, Box 359745, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
Seizure 13:399-402. 2004.... - Do nonspecific focal EEG slowing and epileptiform abnormalities favor one hemisphere?Michael J Doherty
Department of Neurology and Regional Epilepsy Center, University of Washington, Seattle, Washington 98195, USA
Epilepsia 43:1593-5. 2002..In contrast, other pathophysiologies such as stroke lateralize relatively symmetrically. Study of focal slowing and other EEG abnormalities allows assessment of favoring as well as referral and interpretation bias... - Haptoglobin phenotype and apolipoprotein E polymorphism: relationship to posttraumatic seizures and neuropsychological functioning after traumatic brain injuryGail D Anderson
Department of Pharmacy, University of Washington, Box 357630, Seattle, WA 98195, USA
Epilepsy Behav 16:501-6. 2009..In contrast to our hypothesis, those with haptoglobin 1-1 (high-affinity binder of hemoglobin) scored somewhat worse on Verbal IQ and Tapping D at 1 and 12 months after injury... - Real-time functional brain mapping using electrocorticographyKai J Miller
University of Washington, Department of Physics, Box 351560, Seattle, WA 98195 1560, USA
Neuroimage 37:504-7. 2007..We propose that this high-frequency component of the electrocorticogram provides a generic, reliable, clinically useful correlate of local cortical function... - Cognitive impairment is not equal in patients with epileptic and psychogenic nonepileptic seizuresDaniel L Drane
Department of Neurology, University of Washington School of Medicine, Seattle, WA 98104, USA
Epilepsia 47:1879-86. 2006..We reexamined neurocognitive function in patients with ESs and PNES by using symptom validity testing to control for variability in effort... - Long-term outcomes from the PEARLS randomized trial for the treatment of depression in patients with epilepsyNaomi Chaytor
Department of Neurology, University of Washington School of Medicine, Seattle, WA, USA
Epilepsy Behav 20:545-9. 2011..The PEARLS program significantly reduces depressive symptoms in adults with epilepsy, and this effect is maintained for 18 months after baseline and for more than 1 year after completion of home visits... - Progressive dendritic HCN channelopathy during epileptogenesis in the rat pilocarpine model of epilepsySangwook Jung
Department of Neurology, University of Washington, Seattle, Washington 98104, USA
J Neurosci 27:13012-21. 2007..This early and progressive downregulation of dendritic HCN channel function increases neuronal excitability and may be associated with both the process of epileptogenesis and maintenance of the epileptic state... - Does glucocorticoid administration prevent late seizures after head injury?Nathaniel F Watson
Neurology and Sleep Disorders Center, University of Washington, Seattle, Washington 98104 2499, USA
Epilepsia 45:690-4. 2004..Preventing posttraumatic epilepsy has been a difficult challenge. In this study we evaluated the association between glucocorticoid administration after traumatic brain injury (TBI) and posttraumatic seizures... - Factors predicting outcome of surgery for intractable epilepsy with pathologically verified mesial temporal sclerosisSteven G Hardy
Department of Neurology, Regional Epilepsy Center, University of Washington School of Medicine, Seattle, Washington, USA
Epilepsia 44:565-8. 2003..Neurosurgical treatment of MTS can be very effective even in the presence of significant etiologic factors, or of bilateral or extratemporal abnormalities on EEG or MRI... - Vagal nerve stimulation induces intermittent hypocapniaMark D Holmes
Department of Neurology, Regional Epilepsy Center, University of Washington, Seattle, WA, U.S.A
Epilepsia 44:1588-91. 2003..Because carbon dioxide (CO2) has potent effects on various brain functions, it is possible that these transient CO2 changes may have an effect on the state transitions between interictal and preictal states... - SPR imaging-based salivary diagnostics system for the detection of small molecule analytesElain Fu
Department of Bioengineering, University of Washington, Seattle, WA 98195, USA
Ann N Y Acad Sci 1098:335-44. 2007..The multicomponent system includes a hand-portable surface plasmon resonance (SPR) imaging instrument and a disposable microfluidic assay card... - Treatment of out-of-hospital status epilepticus with diazepam rectal gelBrian J Fitzgerald
Department of Neurology and the Regional Epilepsy Center, Fircrest and School of Pharmacy, University of Washington, Seattle 98155, USA
Seizure 12:52-5. 2003..Diazepam rectal gel was given more quickly and reliably, reducing total seizure time, potential neuronal injury and other complications. A treatment protocol for treating status epilepticus with diazepam rectal gel is given... - The absence of interictal spikes with documented seizures suggests extratemporal epilepsyO Stuve
Regional Epilepsy Center, University of Washington, Harborview Medical Center, 325 9th Ave, Seattle, WA 98104 2499, U S A
Epilepsia 42:778-81. 2001..To determine the demographic and clinical characteristics of patients who have documented epileptic seizures on long-term video-EEG monitoring who do not have interictal spikes... - When might hemispheric favouring of epileptiform discharges begin?M J Doherty
Department of Neurology, Regional Epilepsy Center, University of Washington, Seattle, WA 98195, USA
Seizure 12:595-8. 2003..EEG studies based on adult populations report interictal epileptiform discharges (EDS) favour the left hemisphere. It is not clear when favouring becomes apparent as similar paediatric studies have not been performed... - Is the left cerebral hemisphere more prone to epileptogenesis than the right?M D Holmes
EEG and Clinical Neurophysiology Laboratory, Harborview Medical Center, Box 359722, 325 Ninth Ave, Seattle, Washington, USA
Epileptic Disord 3:137-41. 2001..To determine if there is evidence that the left cerebral hemisphere is more prone to epileptogenesis than the right hemisphere... - Age at focal epilepsy onset varies by sex and hemispheric lateralizationM J Doherty
Regional Epilepsy Center and Department of Neurology, University of Washington, Seattle 98195, USA
Neurology 60:1473-7. 2003..This may be due to sex-influenced asymmetric brain maturation. To clarify this relationship, the authors analyzed age at epilepsy onset by sex and by lateralization of epileptiform activity... - Sociodemographic and clinical factors associated with depression in epilepsyAlexander W Thompson
Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195 6560, USA
Epilepsy Behav 14:655-60. 2009..Adjusted for all other variables, subjects with epilepsy reporting lamotrigine use were significantly less likely to be depressed (OR=0.4, 95% CI: 0.2-0.8) compared with those not reporting lamotrigine use... - Post-traumatic epilepsy following fluid percussion injury in the ratRAIMONDO D'AMBROSIO
Department of Neurological Surgery, Center on Human Development and Disability, University of Washington, School of Merdicine, Harborview Medical Center, Box 359914, 325 Ninth Ave, Seattle, WA 98104, USA
Brain 127:304-14. 2004.... - Ictal head version in generalized epilepsyPeter S Chin
Regional Epilepsy Center, Department of Neurology, University of Washington, Seattle, WA 98104, USA
Neurology 63:370-2. 2004..Five patients (25%) demonstrated forced head version, including two with turning to the right and left on consecutive seizures. Forced head turning can occur in generalized epilepsy and may not necessarily indicate focal seizure origin... - Spectral changes in cortical surface potentials during motor movementKai J Miller
Department of Physics, University of Washington, Seattle, Washington 98195, USA
J Neurosci 27:2424-32. 2007..Sensorimotor representation was found to be somatotopic, localized in stereotactic space to rolandic cortex, and typically followed the classic homunculus with limited extrarolandic representation... - Rufinamide: a new anti-epileptic medicationShahin Hakimian
University of Washington, Regional Epilepsy Center, Harborview Medical Center, Seattle, WA 98104, USA
Expert Opin Pharmacother 8:1931-40. 2007..Rufinamide has shown promise as adjunctive treatment for Lennox-Gastaut syndrome and may have some role in localization related epilepsies as well... - Do atmospheric pressure changes influence seizure occurrence in the epilepsy monitoring unit?M J Doherty
Swedish Epilepsy Center, 550 17th Avenue, Suite 540, Seattle, WA 98122, USA
Epilepsy Behav 16:80-1. 2009..We could find no evidence to suggest atmospheric pressure changes made seizure occurrence more likely in any of the seizure groups across any of the time periods... - Very slow EEG responses lateralize temporal lobe seizures: an evaluation of non-invasive DC-EEGS Vanhatalo
Regional Epilepsy Center, Department of Neurology, University of Washington, Seattle 98104, USA
Neurology 60:1098-104. 2003..This method may hold promise in reducing the need for invasive monitoring in patients with TLE where other noninvasive tests are equivocal... - Topography and elimination of slow EEG responses related to tongue movementsS Vanhatalo
Regional Epilepsy Center, Departments of Neurology and Neurological Surgery, University of Washington, Seattle, WA, USA
Neuroimage 20:1419-23. 2003..The topography and small amplitude of TMPs make their off-line rejection difficult, while an isolation method of the kind used here may substantially diminish TMP artifacts in studies on slow cognitive potentials... - Rufinamide: Pharmacology, clinical trials, and role in clinical practiceA Cheng-Hakimian
Department of Neurology, Regional Epilepsy Center, University of Washington, Seattle, WA 98104, USA
Int J Clin Pract 60:1497-501. 2006..Efficacy against partial onset seizures in children has been suggested in an open-label trial. Should rufinamide become commercially available, reserving the drug as a second- or third-line agent should be considered... - The meaning of interictal spikes in temporal lobe epilepsy: should we count them?John W Miller
Neurology 71:392-3. 2008 - Hippocampal sclerosisJohn W Miller
Epilepsia 45:1005; author reply 1005. 2004 - Position statement on the coverage of anticonvulsant drugs for the treatment of epilepsy: what's the problem with generic antiepileptic drugs? A call to actionJohn W Miller
Neurology 69:1806-8. 2007