Charles Miller

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. ncbi request reprint Electrically evoked compound action potentials of guinea pig and cat: responses to monopolar, monophasic stimulation
    C A Miller
    Department of Otolaryngology Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City 52242, USA
    Hear Res 119:142-54. 1998
  2. ncbi request reprint Spiral ganglion cell site of excitation I: comparison of scala tympani and intrameatal electrode responses
    Lianne A Cartee
    Joint Department of Biomedical Engineering, North Carolina State University and the University of North Carolina at Chapel Hill, Box 7625, Raleigh, NC 27695, USA
    Hear Res 215:10-21. 2006
  3. pmc Electrical excitation of the acoustically sensitive auditory nerve: single-fiber responses to electric pulse trains
    Charles A Miller
    Department of Otolaryngology, University of Iowa Hospitals and Clinics, 21201 PFP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    J Assoc Res Otolaryngol 7:195-210. 2006
  4. ncbi request reprint Electrically evoked auditory steady-state responses in Guinea pigs
    Fuh Cherng Jeng
    Department of Speech Pathology and Audiology, Department of Otolaryngology HNS, University of Iowa, Iowa City, Iowa, USA
    Audiol Neurootol 12:101-12. 2007
  5. pmc Acoustic-electric interactions in the guinea pig auditory nerve: simultaneous and forward masking of the electrically evoked compound action potential
    Kirill V Nourski
    Department of Otolaryngology Head and Neck Surgery, The University of Iowa, Iowa City, IA 52242, USA
    Hear Res 232:87-103. 2007
  6. ncbi request reprint Intracochlear and extracochlear ECAPs suggest antidromic action potentials
    Charles A Miller
    Department of Otolaryngology, Head and Neck Surgery, University of Iowa Hospitals and Clinics, 21201 PFP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Hear Res 198:75-86. 2004
  7. ncbi request reprint Feasibility of using silicon-substrate recording electrodes within the auditory nerve
    Charles A Miller
    Department of Otolaryngology, University of Iowa, 21201 PFP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Hear Res 198:48-58. 2004
  8. doi request reprint The clinical application of potentials evoked from the peripheral auditory system
    Charles A Miller
    Department of Otolaryngology, University of Iowa, United States
    Hear Res 242:184-97. 2008
  9. pmc Changes across time in the temporal responses of auditory nerve fibers stimulated by electric pulse trains
    Charles A Miller
    Department of Otolaryngology, University of Iowa Hospitals and Clinics, 21201 PFP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    J Assoc Res Otolaryngol 9:122-37. 2008
  10. ncbi request reprint Electrode configuration influences action potential initiation site and ensemble stochastic response properties
    Charles A Miller
    Department of Otolaryngology, Head and Neck Surgery, University of Iowa, Hospitals and Clinics, 21201 PFP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Hear Res 175:200-14. 2003

Research Grants

  1. Auditory nerve responses to electric pulse trains
    Charles Miller; Fiscal Year: 2007
  2. Auditory nerve responses to electric pulse trains
    Charles Miller; Fiscal Year: 2009

Detail Information

Publications28

  1. ncbi request reprint Electrically evoked compound action potentials of guinea pig and cat: responses to monopolar, monophasic stimulation
    C A Miller
    Department of Otolaryngology Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City 52242, USA
    Hear Res 119:142-54. 1998
    ..Some of our observations also bear upon hypotheses of how electrical stimuli may excite different sites on auditory nerve fibers...
  2. ncbi request reprint Spiral ganglion cell site of excitation I: comparison of scala tympani and intrameatal electrode responses
    Lianne A Cartee
    Joint Department of Biomedical Engineering, North Carolina State University and the University of North Carolina at Chapel Hill, Box 7625, Raleigh, NC 27695, USA
    Hear Res 215:10-21. 2006
    ..Fibers stimulated by an intrameatal electrode demonstrated the greatest range of jitter measurements indicating that greater fiber independence may be achieved with intrameatal stimulation...
  3. pmc Electrical excitation of the acoustically sensitive auditory nerve: single-fiber responses to electric pulse trains
    Charles A Miller
    Department of Otolaryngology, University of Iowa Hospitals and Clinics, 21201 PFP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    J Assoc Res Otolaryngol 7:195-210. 2006
    ..Our findings suggest that bursting is a response unique to sustained electric stimulation in ears with functional hair cells...
  4. ncbi request reprint Electrically evoked auditory steady-state responses in Guinea pigs
    Fuh Cherng Jeng
    Department of Speech Pathology and Audiology, Department of Otolaryngology HNS, University of Iowa, Iowa City, Iowa, USA
    Audiol Neurootol 12:101-12. 2007
    ..As it is evoked by a stimulus that shares important features of cochlear implant stimulation, this evoked potential may be useful in either clinical or basic research efforts...
  5. pmc Acoustic-electric interactions in the guinea pig auditory nerve: simultaneous and forward masking of the electrically evoked compound action potential
    Kirill V Nourski
    Department of Otolaryngology Head and Neck Surgery, The University of Iowa, Iowa City, IA 52242, USA
    Hear Res 232:87-103. 2007
    ..Post-stimulatory changes in synchrony, possibly due to recovery of spontaneous activity and an additional hair-cell independent mechanism, are hypothesized to contribute to the observed non-monotonicity of recovery...
  6. ncbi request reprint Intracochlear and extracochlear ECAPs suggest antidromic action potentials
    Charles A Miller
    Department of Otolaryngology, Head and Neck Surgery, University of Iowa Hospitals and Clinics, 21201 PFP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Hear Res 198:75-86. 2004
    ..Compared with the feline ECAPs, the human potentials had smaller amplitudes and longer latencies. It is not clear what underlies these differences, although several factors are considered...
  7. ncbi request reprint Feasibility of using silicon-substrate recording electrodes within the auditory nerve
    Charles A Miller
    Department of Otolaryngology, University of Iowa, 21201 PFP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Hear Res 198:48-58. 2004
    ..More productive results may be possible from other peripheral nerves with less complex spatial arrangements of fibers...
  8. doi request reprint The clinical application of potentials evoked from the peripheral auditory system
    Charles A Miller
    Department of Otolaryngology, University of Iowa, United States
    Hear Res 242:184-97. 2008
    ..Future research directions, which will likely involve the integration of various dimensions of the electrically evoked response that have been studied in isolation, are also suggested...
  9. pmc Changes across time in the temporal responses of auditory nerve fibers stimulated by electric pulse trains
    Charles A Miller
    Department of Otolaryngology, University of Iowa Hospitals and Clinics, 21201 PFP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    J Assoc Res Otolaryngol 9:122-37. 2008
    ....
  10. ncbi request reprint Electrode configuration influences action potential initiation site and ensemble stochastic response properties
    Charles A Miller
    Department of Otolaryngology, Head and Neck Surgery, University of Iowa, Hospitals and Clinics, 21201 PFP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Hear Res 175:200-14. 2003
    ..These observations and our ECAP results are consistent with reports of perceptual advantages attributed to monopolar or other less-focused modes of stimulation...
  11. pmc Response properties of the refractory auditory nerve fiber
    C A Miller
    Department of Otolaryngology Head and Neck Surgery, University of Iowa, Iowa City 52242, USA
    J Assoc Res Otolaryngol 2:216-32. 2001
    ..Relative spread was found to increase with decreasing MPI values, providing direct evidence that stochastic properties of fibers are altered under conditions of refractoriness...
  12. ncbi request reprint Auditory nerve responses to monophasic and biphasic electric stimuli
    C A Miller
    Department of Otolaryngology, Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City 52242, USA
    Hear Res 151:79-94. 2001
    ..Compared to cats, guinea pigs produced smaller monophasic vs. biphasic threshold differences. This interspecies disparity may be due to differences in cochlear anatomy...
  13. ncbi request reprint An empirically based model of the electrically evoked compound action potential
    C A Miller
    Department of Otolaryngology, Head and Neck Surgery, University of Iowa, Iowa City 52242, USA
    Hear Res 135:1-18. 1999
    ..Discrepancies between these two models do occur if the threshold distribution function is compressed significantly, as might be the case in pathological cochleae with altered distributions or numbers of nerve fibers...
  14. ncbi request reprint Electrically evoked single-fiber action potentials from cat: responses to monopolar, monophasic stimulation
    C A Miller
    Department of Otolaryngology, Head and Neck Surgery, University of Iowa, Iowa City 52242, USA
    Hear Res 130:197-218. 1999
    ....
  15. pmc Auditory nerve fiber responses to combined acoustic and electric stimulation
    Charles A Miller
    Department of Otolaryngology Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    J Assoc Res Otolaryngol 10:425-45. 2009
    ....
  16. ncbi request reprint Electrically evoked auditory steady-state responses in a guinea pig model: latency estimates and effects of stimulus parameters
    Fuh Cherng Jeng
    Department of Speech Pathology and Audiology, University of Iowa, Iowa City, Iowa, USA
    Audiol Neurootol 13:161-71. 2008
    ..Furthermore, response amplitudes declined with increasing carrier frequency, exhibited a compressive growth with increasing modulation depths, and were sensitive to modulation depths to as low as 5%...
  17. ncbi request reprint Response of the auditory nerve to sinusoidal electrical stimulation: effects of high-rate pulse trains
    Christina L Runge-Samuelson
    Department of Speech Pathology and Audiology, University of Iowa, Iowa City, IA 52242, USA
    Hear Res 194:1-13. 2004
    ....
  18. ncbi request reprint Effects of electrode-to-fiber distance on temporal neural response with electrical stimulation
    Hiroyuki Mino
    Department of Otolaryngology Head and Neck Surgery, The University of Iowa College of Medicine, Iowa City, IA 52242, USA
    IEEE Trans Biomed Eng 51:13-20. 2004
    ....
  19. ncbi request reprint Auditory response to intracochlear electric stimuli following furosemide treatment
    Ning Hu
    Department of Otolaryngology Head and Neck Surgery, University of Iowa, Iowa City, IA 52242, USA
    Hear Res 185:77-89. 2003
    ..Viable hair cells may therefore provide positive effects on auditory response to electric stimuli delivered to implant patients with residual hearing, as they may enhance the random activity of the stimulated nerve...
  20. pmc Changes across time in spike rate and spike amplitude of auditory nerve fibers stimulated by electric pulse trains
    Fawen Zhang
    Department of Otolaryngology, University of Iowa Hospitals and Clinics, 21201 PFP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    J Assoc Res Otolaryngol 8:356-72. 2007
    ....
  21. doi request reprint Simulation of the electrically stimulated cochlear neuron: modeling adaptation to trains of electric pulses
    Jihwan Woo
    Department of Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    IEEE Trans Biomed Eng 56:1348-59. 2009
    ....
  22. doi request reprint Biophysical model of an auditory nerve fiber with a novel adaptation component
    Jihwan Woo
    Department of Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    IEEE Trans Biomed Eng 56:2177-80. 2009
    ..Furthermore, this mechanism could be easily incorporated into other models to produce much more realistic estimates of the neural coding produced by repeated electric stimulation...
  23. ncbi request reprint Design, analysis and simulation for development of the first clinical micro-CT scanner
    Ge Wang
    CT Micro CT Laboratory, Department of Radiology, University of Iowa, Iowa City, IA 52242, USA
    Acad Radiol 12:511-25. 2005
    ..Imaging of microarchitectures of the cancellous bone would be also an important application...
  24. ncbi request reprint Effects of acoustic noise on the auditory nerve compound action potentials evoked by electric pulse trains
    Kirill V Nourski
    Department of Otolaryngology Head and Neck Surgery, University of Iowa, Iowa City, 52242, USA
    Hear Res 202:141-53. 2005
    ..The observed effects of noise on ECAP were the greatest at high electric stimulus levels and, for a particular electric stimulus level, at high acoustic noise levels...
  25. ncbi request reprint Channel interaction in cochlear implant users evaluated using the electrically evoked compound action potential
    Paul J Abbas
    Department of Speech Pathology and Audiology, University of Iowa, Iowa City, 52242, USA
    Audiol Neurootol 9:203-13. 2004
    ..Results demonstrate large variations across individual implant users as well as across electrodes within an individual. In general, the degree of interaction is shown to be dependent on stimulus level...
  26. pmc The dependence of auditory nerve rate adaptation on electric stimulus parameters, electrode position, and fiber diameter: a computer model study
    Jihwan Woo
    Department of Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    J Assoc Res Otolaryngol 11:283-96. 2010
    ..These results are compared against available feline ANF data, and possible effects of individual parameters are discussed...
  27. ncbi request reprint Co-administration of kanamycin and ethacrynic acid as a deafening method for acute animal experiments
    Kirill V Nourski
    Department of Otolaryngology Head and Neck Surgery, The University of Iowa, 21210 PFP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Hear Res 187:131-3. 2004
  28. ncbi request reprint Improved noise reduction in single fiber auditory neural responses using template subtraction
    Jihwan Woo
    Department of Biomedical Engineering, Hanyang University, Seoul, Republic of Korea
    J Neurosci Methods 155:319-27. 2006
    ..An improvement (reduction) in the noise level is reported, as are suggestions for future implementation of this strategy...

Research Grants5

  1. Auditory nerve responses to electric pulse trains
    Charles Miller; Fiscal Year: 2007
    ..We expect the results of this work will guide future designs of cochlear-implant speech processors so that modulated stimuli can be better tailored to the encoding capacity of the user's auditory nerve. ..
  2. Auditory nerve responses to electric pulse trains
    Charles Miller; Fiscal Year: 2009
    ..We expect the results of this work will guide future designs of cochlear-implant speech processors so that modulated stimuli can be better tailored to the encoding capacity of the user's auditory nerve. ..