TED RICHARD MIKULS

Summary

Affiliation: University of Nebraska Medical Center
Country: USA

Publications

  1. doi request reprint Prospective study of posttraumatic stress disorder and disease activity outcomes in US veterans with rheumatoid arthritis
    Ted R Mikuls
    Omaha VAMC and University of Nebraska Medical Center, Omaha, NE 68198 6270, USA
    Arthritis Care Res (Hoboken) 65:227-34. 2013
  2. pmc Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis
    Ted R Mikuls
    Omaha VA Medical Center, NE, USA
    Arthritis Rheum 64:3522-30. 2012
  3. pmc Association between being African-American, serum urate levels and the risk of developing hyperuricemia: findings from the Coronary Artery Risk Development in Young Adults cohort
    Angelo L Gaffo
    Birmingham VA Medical Center 700 South 19th Street, Birmingham, AL 35233, USA
    Arthritis Res Ther 14:R4. 2012
  4. pmc Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis
    Jeffrey R Curtis
    Department of Medicine, University of Alabama, 510 20th Street South, FOT 805D, Birmingham, AL 35294, USA
    Arthritis Res Ther 13:R155. 2011
  5. pmc Impact of interactions of cigarette smoking with NAT2 polymorphisms on rheumatoid arthritis risk in African Americans
    Ted R Mikuls
    Department of Medicine, University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, NE 68198 6270, USA
    Arthritis Rheum 64:655-64. 2012
  6. pmc Development of a macromolecular prodrug for the treatment of inflammatory arthritis: mechanisms involved in arthrotropism and sustained therapeutic efficacy
    Ling Dong Quan
    Department of Pharmaceutical Sciences, University of Nebraska Medical Center, 986025 Nebraska Medical Center, Omaha, NE 68198 6025, USA
    Arthritis Res Ther 12:R170. 2010
  7. pmc Anticitrullinated protein antibody (ACPA) in rheumatoid arthritis: influence of an interaction between HLA-DRB1 shared epitope and a deletion polymorphism in glutathione S-transferase in a cross-sectional study
    Ted R Mikuls
    Omaha Veterans Affairs Medical Center and Nebraska Arthritis Outcomes Research Center, University of Nebraska Medical Center, 986270 Nebraska Medical Center, Omaha, NE 68198 6270, USA
    Arthritis Res Ther 12:R213. 2010
  8. doi request reprint Soluble CD14 and CD14 polymorphisms in rheumatoid arthritis
    Ted R Mikuls
    Department of Medicine, Division of Rheumatology and Immunology, Omaha Veterans Affairs Medical Center and University of Nebraska Medical Center, Omaha, NE, USA
    J Rheumatol 38:2509-16. 2011
  9. pmc Associations of cigarette smoking with rheumatoid arthritis in African Americans
    Ted R Mikuls
    University of Nebraska Medical Center and Omaha Veterans Affairs Medical Center, Omaha, USA
    Arthritis Rheum 62:3560-8. 2010
  10. pmc Associations of disease activity and treatments with mortality in men with rheumatoid arthritis: results from the VARA registry
    Ted R Mikuls
    Department of Medicine, Omaha Veterans Affairs Medical Center VAMC, University of Nebraska, Omaha, NE 68198 6270, USA
    Rheumatology (Oxford) 50:101-9. 2011

Detail Information

Publications30

  1. doi request reprint Prospective study of posttraumatic stress disorder and disease activity outcomes in US veterans with rheumatoid arthritis
    Ted R Mikuls
    Omaha VAMC and University of Nebraska Medical Center, Omaha, NE 68198 6270, USA
    Arthritis Care Res (Hoboken) 65:227-34. 2013
    ..To examine the relationship between posttraumatic stress disorder (PTSD) and disease activity in US veterans with rheumatoid arthritis (RA)...
  2. pmc Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis
    Ted R Mikuls
    Omaha VA Medical Center, NE, USA
    Arthritis Rheum 64:3522-30. 2012
    ..To examine the relationship of Porphyromonas gingivalis to the presence of autoantibodies in individuals at risk of rheumatoid arthritis (RA)...
  3. pmc Association between being African-American, serum urate levels and the risk of developing hyperuricemia: findings from the Coronary Artery Risk Development in Young Adults cohort
    Angelo L Gaffo
    Birmingham VA Medical Center 700 South 19th Street, Birmingham, AL 35233, USA
    Arthritis Res Ther 14:R4. 2012
    ..We tested this hypothesis in a bi-racial cohort of younger African-American and white men and women...
  4. pmc Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis
    Jeffrey R Curtis
    Department of Medicine, University of Alabama, 510 20th Street South, FOT 805D, Birmingham, AL 35294, USA
    Arthritis Res Ther 13:R155. 2011
    ..We created and tested a claims-based algorithm to serve as a proxy for the clinical effectiveness of RA medications...
  5. pmc Impact of interactions of cigarette smoking with NAT2 polymorphisms on rheumatoid arthritis risk in African Americans
    Ted R Mikuls
    Department of Medicine, University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, NE 68198 6270, USA
    Arthritis Rheum 64:655-64. 2012
    ..To examine whether polymorphisms in genes coding for drug-metabolizing enzymes (DMEs) have an impact on rheumatoid arthritis (RA) risk due to cigarette smoking in African Americans...
  6. pmc Development of a macromolecular prodrug for the treatment of inflammatory arthritis: mechanisms involved in arthrotropism and sustained therapeutic efficacy
    Ling Dong Quan
    Department of Pharmaceutical Sciences, University of Nebraska Medical Center, 986025 Nebraska Medical Center, Omaha, NE 68198 6025, USA
    Arthritis Res Ther 12:R170. 2010
    ....
  7. pmc Anticitrullinated protein antibody (ACPA) in rheumatoid arthritis: influence of an interaction between HLA-DRB1 shared epitope and a deletion polymorphism in glutathione S-transferase in a cross-sectional study
    Ted R Mikuls
    Omaha Veterans Affairs Medical Center and Nebraska Arthritis Outcomes Research Center, University of Nebraska Medical Center, 986270 Nebraska Medical Center, Omaha, NE 68198 6270, USA
    Arthritis Res Ther 12:R213. 2010
    ..The purpose of this study was to examine the associations of GSTM1-null with ACPA positivity in RA and to assess for evidence of interaction between GSTM1 and HLA-DRB1 shared epitope (SE)...
  8. doi request reprint Soluble CD14 and CD14 polymorphisms in rheumatoid arthritis
    Ted R Mikuls
    Department of Medicine, Division of Rheumatology and Immunology, Omaha Veterans Affairs Medical Center and University of Nebraska Medical Center, Omaha, NE, USA
    J Rheumatol 38:2509-16. 2011
    ..We also examined whether well-defined polymorphisms in CD14 are associated with sCD14 expression in RA...
  9. pmc Associations of cigarette smoking with rheumatoid arthritis in African Americans
    Ted R Mikuls
    University of Nebraska Medical Center and Omaha Veterans Affairs Medical Center, Omaha, USA
    Arthritis Rheum 62:3560-8. 2010
    ..To examine the associations of cigarette smoking with rheumatoid arthritis (RA) in African Americans, and to determine whether this association is impacted by the HLA-DRB1 shared epitope (SE)...
  10. pmc Associations of disease activity and treatments with mortality in men with rheumatoid arthritis: results from the VARA registry
    Ted R Mikuls
    Department of Medicine, Omaha Veterans Affairs Medical Center VAMC, University of Nebraska, Omaha, NE 68198 6270, USA
    Rheumatology (Oxford) 50:101-9. 2011
    ..To examine the all-cause mortality rate and factors associated with mortality in US veteran men with RA...
  11. pmc Antibody responses to Porphyromonas gingivalis (P. gingivalis) in subjects with rheumatoid arthritis and periodontitis
    Ted R Mikuls
    Department of Medicine, Nebraska Arthritis Outcomes Research Center NAORC, University of Nebraska Medical Center and Omaha Veterans Affairs Medical Center, Omaha, NE, USA
    Int Immunopharmacol 9:38-42. 2009
    ..Antibody titers to P. gingivalis are increased in patients with rheumatoid arthritis and are associated with disease-specific autoimmunity...
  12. pmc Cigarette smoking, disease severity and autoantibody expression in African Americans with recent-onset rheumatoid arthritis
    T R Mikuls
    Department of Medicine, University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, NE 68198 6270, USA
    Ann Rheum Dis 67:1529-34. 2008
    ....
  13. ncbi request reprint Quality of care in gout: from measurement to improvement
    T R Mikuls
    Department of Internal Medicine, Section of Rheumatology and Immunology, University of Nebraska Medical Center, 986270 Nebraska Medical Center, Omaha, NE 68198 6270, USA
    Clin Exp Rheumatol 25:114-9. 2007
    ..quot;If you can not measure it, you can not improve it" - Lord Kelvin...
  14. ncbi request reprint The association of race and ethnicity with disease expression in male US veterans with rheumatoid arthritis
    Ted R Mikuls
    Omaha Veterans Affairs Medical Center, University of Nebraska, Omaha, Nebraska, USA
    J Rheumatol 34:1480-4. 2007
    ..To examine the association of race/ethnicity with measures of disease activity and severity among male US veterans with rheumatoid arthritis (RA)...
  15. ncbi request reprint Association of rheumatoid arthritis treatment response and disease duration with declines in serum levels of IgM rheumatoid factor and anti-cyclic citrullinated peptide antibody
    T R Mikuls
    Department of Medicine, University of Nebraska Medical Center, Omaha, Nebraska 68198, USA
    Arthritis Rheum 50:3776-82. 2004
    ..To examine the association of treatment response and disease duration with changes in rheumatoid factor (RF) and anti-cyclic citrullinated peptide (anti-CCP) antibody levels among patients with rheumatoid arthritis (RA)...
  16. ncbi request reprint Lessons learned in the use of tumor necrosis factor-alpha inhibitors in the treatment of rheumatoid arthritis
    Ted R Mikuls
    Section of Rheumatology and Immunology, University of Nebraska Medical Center and the Omaha Veterans Administration Medical Center, 983025 Nebraska Medical Center, Omaha, NE 68198, USA
    Curr Rheumatol Rep 5:270-7. 2003
    ..This review evaluates the unique attributes of the available TNFa inhibitors, focusing specifically on recent reports providing important insight into the understanding of drug-related efficacy and toxicity...
  17. ncbi request reprint Co-morbidity in rheumatoid arthritis
    Ted R Mikuls
    Department of Internal Medicine, Section of Rheumatology and Immunology, University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, NE 68198 3025, USA
    Best Pract Res Clin Rheumatol 17:729-52. 2003
    ....
  18. ncbi request reprint Racial disparities in the receipt of osteoporosis related healthcare among community-dwelling older women with arthritis and previous fracture
    Ted R Mikuls
    Department of Medicine, Section of Rheumatology and Immunology, University of Nebraska Medical Center, Omaha, Nebraska 68198 3025, USA
    J Rheumatol 32:870-5. 2005
    ..To examine potential racial/ethnic disparities in osteoporosis care among community-dwelling older women with self-reported arthritis and previous fracture...
  19. ncbi request reprint Health related quality of life in women with elderly onset rheumatoid arthritis
    Ted Mikuls
    Department of Medicine, University of Nebraska Medical Center and the Omaha VA Medical Center, Omaha, Nebraska 68198, USA
    J Rheumatol 30:952-7. 2003
    ..To examine the association of elderly onset rheumatoid arthritis (RA) with health related quality of life in a population based cohort of older women...
  20. ncbi request reprint Benefit-risk assessment of infliximab in the treatment of rheumatoid arthritis
    Ted R Mikuls
    Department of Medicine, Section of Rheumatology and Immunology, University of Nebraska Medical Center, Omaha, Nebraska, USA
    Drug Saf 26:23-32. 2003
    ..Despite its potential for toxicity, infliximab remains a valuable alternative for patients with rheumatoid arthritis...
  21. ncbi request reprint Gout treatment: what is evidence-based and how do we determine and promote optimized clinical care?
    Ted R Mikuls
    University of Nebraska Medical Center and the Omaha VA Medical Center, 983025 NE Med Center, Omaha, NE 68198 3025, USA
    Curr Rheumatol Rep 7:242-9. 2005
    ..We also discuss the need for future initiatives aimed at improving patient safety and quality of care in gout...
  22. pmc Prevalence of osteoporosis and osteopenia among African Americans with early rheumatoid arthritis: the impact of ethnic-specific normative data
    Ted R Mikuls
    Department of Medicine, University of Nebraska Medica Center and Omaha VA Medical Center, Omaha, NE 68198 3025, USA
    J Natl Med Assoc 97:1155-60. 2005
    ..To examine the prevalence of osteopenia and/or osteoporosis among African Americans with early rheumatoid arthritis (RA) and to assess the effect of using race/ethnicity-specific normative data...
  23. ncbi request reprint Prospective study of survival outcomes in Non-Hodgkin's lymphoma patients with rheumatoid arthritis
    Ted R Mikuls
    Department of Medicine, University of Nebraska Medical Center, Omaha, NE 68198 3025, USA
    J Clin Oncol 24:1597-602. 2006
    ..In this prospective study, we examined the association of RA with survival in patients with NHL...
  24. ncbi request reprint Quality of care indicators for gout management
    Ted R Mikuls
    University of Nebraska Medical Center, and Omaha Veterans Administration Medical Center, Omaha, Nebraska 68198 3025, USA
    Arthritis Rheum 50:937-43. 2004
    ..Despite the significant health impact of gout, there is no consensus on management standards. To guide physician practice, we sought to develop quality of care indicators for gout management...
  25. pmc Smoking interacts with genetic risk factors in the development of rheumatoid arthritis among older Caucasian women
    L A Criswell
    Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, University of California, San Francisco, CA, USA
    Ann Rheum Dis 65:1163-7. 2006
    ..To determine whether the impact of tobacco exposure on rheumatoid arthritis (RA) risk is influenced by polymorphisms at the HLA-DRB1 and glutathione S-transferase M1 (GSTM1) loci...
  26. ncbi request reprint Poor to modest agreement between rheumatoid arthritis response measures in clinical practice
    K Michaud
    VA Medical Center and Nebraska Arthritis Outcomes Research Center, University of Nebraska Medical Center, Omaha, Nebraska, USA
    Clin Exp Rheumatol 27:633-40. 2009
    ..To evaluate the agreement among several rheumatoid arthritis (RA) response measures in a clinical setting...
  27. pmc Gout epidemiology: results from the UK General Practice Research Database, 1990-1999
    T R Mikuls
    Department of Medicine, University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, NE, USA
    Ann Rheum Dis 64:267-72. 2005
    ..To examine the epidemiology of gout and gout treatment in the United Kingdom using a large national practice based population...
  28. ncbi request reprint Suboptimal physician adherence to quality indicators for the management of gout and asymptomatic hyperuricaemia: results from the UK General Practice Research Database (GPRD)
    T R Mikuls
    Department of Medicine, Division of Clinical Immunology and Rheumatology, 510 20th Street South, FOT 8th Floor, Birmingham, AL 35294, USA
    Rheumatology (Oxford) 44:1038-42. 2005
    ..To examine adherence to validated quality indicators assessing the quality of allopurinol use in the treatment of gout and asymptomatic hyperuricaemia...
  29. pmc Mortality risk associated with rheumatoid arthritis in a prospective cohort of older women: results from the Iowa Women's Health Study
    T R Mikuls
    Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, 35294, USA
    Ann Rheum Dis 61:994-9. 2002
    ..To determine whether rheumatoid arthritis (RA) is associated with excess mortality among older women...
  30. ncbi request reprint Comorbidity in rheumatoid arthritis
    T R Mikuls
    Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Rheum Dis Clin North Am 27:283-303. 2001
    ..The next decade should prove to be an exciting time in RA management. Better identification, understanding, and management of RA comorbidities have great potential to improve quality of life and survival among our patients with RA...

Research Grants4

  1. Gene-Environment Interactions in RA Autoimmunity and Disease Severity
    Ted Mikuls; Fiscal Year: 2007
    ..We anticipate that the results of this study will be extended to other RA populations. ..
  2. RA Comorbidity Bone Health in Men and African Americans
    Ted Mikuls; Fiscal Year: 2007
    ..Mikuls' continued development as an independent clinical investigator. ..