J R Middleton

Summary

Affiliation: University of Missouri
Country: USA

Publications

  1. ncbi request reprint Risk of after-hours visits to an in-hospital food animal service by species
    Jeff W Tyler
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine and Surgery, University of Missouri, Columbia 65211, USA
    J Vet Intern Med 20:407-9. 2006
  2. ncbi request reprint Efficacy of different Lysigin formulations in the prevention of Staphylococcus aureus intramammary infection in dairy heifers
    John R Middleton
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, Missouri, USA
    J Dairy Res 73:10-9. 2006
  3. ncbi request reprint Short communication: influence of Staphylococcus aureus intramammary infection on serum copper, zinc, and iron concentrations
    J R Middleton
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia 65211, USA
    J Dairy Sci 87:976-9. 2004
  4. ncbi request reprint Dysautonomia and salmonellosis in an 11-year-old female llama (Lama glama)
    John R Middleton
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65211, USA
    J Vet Intern Med 20:213-6. 2006
  5. ncbi request reprint Characterization of the antibody isotype response in serum and milk of heifers vaccinated with a Staphylococcus aureus bacterin (Lysigin)
    Christopher D Luby
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, USA
    J Dairy Res 74:239-46. 2007
  6. pmc Surveillance of Staphylococcus aureus in veterinary teaching hospitals
    John R Middleton
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65211, USA
    J Clin Microbiol 43:2916-9. 2005
  7. doi request reprint Staphylococcus aureus antigens and challenges in vaccine development
    John R Middleton
    Department of Veterinary Medicine and Surgery, University of Missouri, 900 East Campus Drive, Columbia, MO 65211, USA
    Expert Rev Vaccines 7:805-15. 2008
  8. ncbi request reprint Influence of Staphylococcus aureus strain-type on mammary quarter milk somatic cell count and N-acetyl-beta-D-glucosaminidase activity in cattle from eight dairies
    J R Middleton
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia 65211, USA
    J Dairy Sci 85:1133-40. 2002
  9. pmc Use of pulsed-field gel electrophoresis for detecting differences in Staphylococcus aureus strain populations between dairy herds with different cattle importation practices
    J R Middleton
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65211, USA
    Epidemiol Infect 129:387-95. 2002
  10. ncbi request reprint Technical note: Therapeutic cessation of lactation of Staphylococcus aureus-infected mammary quarters
    J R Middleton
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia 65211, USA
    J Dairy Sci 84:1976-8. 2001

Collaborators

Detail Information

Publications40

  1. ncbi request reprint Risk of after-hours visits to an in-hospital food animal service by species
    Jeff W Tyler
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine and Surgery, University of Missouri, Columbia 65211, USA
    J Vet Intern Med 20:407-9. 2006
    ..51) and increased in South American camelidae (RR = 3.04) and sheep or goats (RR = 1.66). The likelihood of an after-hours admission differed significantly among groups...
  2. ncbi request reprint Efficacy of different Lysigin formulations in the prevention of Staphylococcus aureus intramammary infection in dairy heifers
    John R Middleton
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, Missouri, USA
    J Dairy Res 73:10-9. 2006
    ..aureus IMI, but Lysigin showed benefit in reducing the clinical severity and duration of clinical disease post-challenge. Neither of the experimental bacterins appeared to perform better than Lysigin...
  3. ncbi request reprint Short communication: influence of Staphylococcus aureus intramammary infection on serum copper, zinc, and iron concentrations
    J R Middleton
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia 65211, USA
    J Dairy Sci 87:976-9. 2004
    ..The reductions in trace mineral concentrations were of less magnitude than observed following experimental E. coli mastitis...
  4. ncbi request reprint Dysautonomia and salmonellosis in an 11-year-old female llama (Lama glama)
    John R Middleton
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65211, USA
    J Vet Intern Med 20:213-6. 2006
  5. ncbi request reprint Characterization of the antibody isotype response in serum and milk of heifers vaccinated with a Staphylococcus aureus bacterin (Lysigin)
    Christopher D Luby
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, USA
    J Dairy Res 74:239-46. 2007
    ..aureus (P< or = 0.030). Hence, a humoural immune response to the vaccine was detected in serum and milk, but responses varied according to strain and antibody isotype tested...
  6. pmc Surveillance of Staphylococcus aureus in veterinary teaching hospitals
    John R Middleton
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65211, USA
    J Clin Microbiol 43:2916-9. 2005
    ..222). Methicillin-resistant S. aureus isolates in this study seemed to be community acquired rather than hospital acquired...
  7. doi request reprint Staphylococcus aureus antigens and challenges in vaccine development
    John R Middleton
    Department of Veterinary Medicine and Surgery, University of Missouri, 900 East Campus Drive, Columbia, MO 65211, USA
    Expert Rev Vaccines 7:805-15. 2008
    ..aureus vaccines developed have adequately prevented new infection. The antigens targeted by S. aureus vaccines and potential reasons for the lack of success of vaccination against S. aureus are reviewed in this article...
  8. ncbi request reprint Influence of Staphylococcus aureus strain-type on mammary quarter milk somatic cell count and N-acetyl-beta-D-glucosaminidase activity in cattle from eight dairies
    J R Middleton
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia 65211, USA
    J Dairy Sci 85:1133-40. 2002
    ..Overall, no significant differences were found between strains, suggesting that the degree of udder parenchymal injury induced by S. aureus IMI is in general significantly affected by factors other than strain type...
  9. pmc Use of pulsed-field gel electrophoresis for detecting differences in Staphylococcus aureus strain populations between dairy herds with different cattle importation practices
    J R Middleton
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65211, USA
    Epidemiol Infect 129:387-95. 2002
    ..02). Herds that purchased replacement heifers had more total strains of Staphylococcus aureus (P = 0.01) and more new strains (P = 0.04) enter the herd than closed herds...
  10. ncbi request reprint Technical note: Therapeutic cessation of lactation of Staphylococcus aureus-infected mammary quarters
    J R Middleton
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia 65211, USA
    J Dairy Sci 84:1976-8. 2001
    ..No difference in total milk production between lactation one and two in either group was found, suggesting that permanent loss of a quarter was not detrimental to overall milk production...
  11. ncbi request reprint Efficacy of vaccination and antibiotic therapy against Staphylococcus aureus mastitis in dairy cattle
    C D Luby
    Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65211, USA
    Vet Rec 157:89-90. 2005
  12. doi request reprint Prevalence of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus carriage in three populations
    S Kottler
    Department of Veterinary Medicine and Surgery, University of Missouri College of Veterinary Medicine, Columbia, MO, USA
    J Vet Intern Med 24:132-9. 2010
    ..A higher prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonization is reported in healthcare workers compared with nonhealthcare workers...
  13. ncbi request reprint Escherichia coli mastitis in cattle being treated for Staphylococcus aureus intramammary infection
    J R Middleton
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    Vet Rec 162:156-7. 2008
  14. ncbi request reprint Detection of low serum immunoglobulin concentrations in clinically ill calves
    J W Tyler
    Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, USA
    J Vet Intern Med 13:40-3. 1999
    ..The zinc sulfate turbidity test was inadequately specific (0.33) and resulted in misclassification of 33% of calves...
  15. doi request reprint A veterinary perspective on methicillin-resistant staphylococci
    Leah A Cohn
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    J Vet Emerg Crit Care (San Antonio) 20:31-45. 2010
    ..To familiarize the reader with the epidemiology, diagnosis, and infectious and zoonotic potential of methicillin-resistant staphylococci...
  16. ncbi request reprint West Nile virus encephalomyelitis in a sheep
    Jeff W Tyler
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    J Vet Intern Med 17:242-4. 2003
  17. ncbi request reprint Transmissible spongiform encephalopathies in ruminants
    Jeff W Tyler
    Department of Veterinary Medicine and Surgery, University of Missouri, 379 East Campus Drive, Columbia, MO 65211, USA
    Vet Clin North Am Food Anim Pract 20:303-26, vii. 2004
    ..Mechanisms of TSE transmission vary among host species. The diagnostic approach for TSEs of ruminants is presented,and the history and justification of regulatory programs to control and eradicate TSEs are outlined...
  18. ncbi request reprint Effect of prepartum intramammary treatment with pirlimycin hydrochloride on prevalence of early first-lactation mastitis in dairy heifers
    John R Middleton
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    J Am Vet Med Assoc 227:1969-74. 2005
    ....
  19. ncbi request reprint Enteral feeding of 3 mature cows by rumenostomy
    Munashe Chigerwe
    Departments of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO, USA
    J Vet Intern Med 19:779-81. 2005
  20. ncbi request reprint Acanthomatous ameloblastoma of the maxilla of an adult alpaca
    Lisa G Britt
    Department of Veterinary Medicine and Surgery, University of Missouri, College of Veterinary Medicine, Clydesdale Hall 379 E Campus Drive, Columbia, MO 65211, USA
    Vet Radiol Ultrasound 46:65-8. 2005
    ..An ameloblastoma was diagnosed histologically and palliative radiation therapy was attempted. Because of poor response to therapy and anorexia the animal was euthanized. Necropsy findings confirmed an ameloblastoma of acanthomatous type...
  21. ncbi request reprint Antigenic evaluation of a recombinant baculovirus-expressed Sarcocystis neurona SAG1 antigen
    G D Gupta
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, Missouri 65211, USA
    J Parasitol 90:1027-33. 2004
    ..This is the first report of a baculovirus-expressed recombinant S. neurona antigen being used to detect anti-S. neurona antibodies in a variety of host species...
  22. ncbi request reprint Use of somatic cell counts and California mastitis test results from individual quarter milk samples to detect subclinical intramammary infection in dairy cattle from a herd with a high bulk tank somatic cell count
    John R Middleton
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    J Am Vet Med Assoc 224:419-23. 2004
    ..To determine whether somatic cell counts (SCCs) or California mastitis test (CMT) scores for individual quarter milk samples could be used to detect subclinical intramammary infection among dairy cattle in a herd with a high bulk tank SCC...
  23. doi request reprint Efficacy of vaccination against staphylococcal mastitis: a review and new data
    John R Middleton
    Department of Veterinary Medicine and Surgery, University of Missouri, 900 East Campus Drive, Columbia, MO 65211, United States
    Vet Microbiol 134:192-8. 2009
    ..There may be insufficient vaccine-induced opsonizing antibody in milk to facilitate phagocytosis and clearance of staphylococci from the mammary gland...
  24. ncbi request reprint Elimination kinetics of chlorhexidine in milk following intramammary infusion to stop lactation in mastitic mammary gland quarters of cows
    John R Middleton
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    J Am Vet Med Assoc 222:1746-9. 2003
    ..To evaluate the elimination kinetics of chlorhexidine in milk when used as an intramammary infusion to stop lactation in cows...
  25. ncbi request reprint Diabetes mellitus in an adult alpaca (Lama pacos)
    J R Middleton
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    Vet Rec 157:520-2. 2005
  26. ncbi request reprint Pharmacokinetics of intravenously administered caffeine in healthy alpacas (Lama pacos) and llamas (Lama glama)
    Jeffrey Lakritz
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    Am J Vet Res 67:1063-9. 2006
    ..To determine the pharmacokinetic disposition of IV administered caffeine in healthy Lama spp camelids...
  27. ncbi request reprint Theriogenology question of the month. Sertoli cell tumor
    Christopher D Luby
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    J Am Vet Med Assoc 231:1503-5. 2007
  28. ncbi request reprint Evaluation of a cow-side immunoassay kit for assessing IgG concentration in colostrum
    Munashe Chigerwe
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    J Am Vet Med Assoc 227:129-31. 2005
    ..To determine sensitivity and specificity of a cow-side immunoassay kit for assessing IgG concentration in colostrum...
  29. ncbi request reprint Pulmonary hypertension and right-sided heart failure in an adult llama with hepatic disease
    John R Middleton
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    J Am Vet Med Assoc 228:756-9. 2006
    ..A 13-year-old llama was examined because of lethargy, inappetence, and syncope...
  30. doi request reprint Comparison of four methods to assess colostral IgG concentration in dairy cows
    Munashe Chigerwe
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    J Am Vet Med Assoc 233:761-6. 2008
    ..To determine sensitivity and specificity of 4 methods to assess colostral IgG concentration in dairy cows and determine the optimal cutpoint for each method...
  31. ncbi request reprint Copper toxicosis with hemolysis and hemoglobinuric nephrosis in three adult Boer goats
    Chantelle C Bozynski
    Veterinary Medical Diagnostic Laboratory, 1600 East Rollins, Columbia, MO 65211, USA
    J Vet Diagn Invest 21:395-400. 2009
    ..Consideration also should be given to the ingestion of hepatotoxic plants and other toxic exposures, which could predispose an animal to secondary chronic copper toxicosis...
  32. doi request reprint Evaluation of factors affecting serum IgG concentrations in bottle-fed calves
    Munashe Chigerwe
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    J Am Vet Med Assoc 234:785-9. 2009
    ....
  33. doi request reprint Effects of general anesthesia on plasma colloid oncotic pressure in dogs
    David I Dismukes
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    J Am Vet Med Assoc 236:309-11. 2010
    ..To determine the magnitude of the change in colloid oncotic pressure (COP) associated with general anesthesia in dogs undergoing a variety of elective procedures...
  34. doi request reprint Effect of colostrum administration by use of oroesophageal intubation on serum IgG concentrations in Holstein bull calves
    Munashe Chigerwe
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    Am J Vet Res 69:1158-63. 2008
    ....
  35. doi request reprint Frequency of detectable serum IgG concentrations in precolostral calves
    Munashe Chigerwe
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    Am J Vet Res 69:791-5. 2008
    ....
  36. ncbi request reprint Malignant melanoma of the horn base in a Pygora goat
    Vengai Mavangira
    Department of Veterinary Medicine and Surgery, 900 East Campus Drive, Columbia, MO 65211, USA
    J Vet Diagn Invest 20:104-7. 2008
    ..The tumor cells were positive for Melan A by immunohistochemical staining...
  37. ncbi request reprint Atypical coccidiosis in South American camelids
    Munashe Chigerwe
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    J Vet Diagn Invest 19:122-5. 2007
    ..This report describes 2 atypical cases of coccidiosis in South American camelids that had no coccidial oocysts detected on antemortem fecal flotation, prolonged weight loss, and normal fecal consistency...
  38. ncbi request reprint An alternative method to assess efficiency of estrus detection in dairy herds
    Munashe Chigerwe
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    J Am Vet Med Assoc 226:1050-2. 2005
  39. ncbi request reprint Effect of delayed colostrum collection on colostral IgG concentration in dairy cows
    Malantus Moore
    Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
    J Am Vet Med Assoc 226:1375-7. 2005
    ..To determine the effect of timing of first-milking colostrum collection on colostral IgG concentration...
  40. ncbi request reprint Methodology for quantifying residues of chlorhexidine in raw dairy milk
    Vincent R Hebert
    Food and Environmental Quality Laboratory, Washington State University, 2710 University Drive, Richland, Washington 99352, USA
    J Agric Food Chem 51:567-70. 2003
    ..The residue method was found to be rugged with a lower detection limit of 0.1 ppm...