Research Topics
| J R MiddletonSummaryAffiliation: University of Missouri Country: USA Publications
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Detail Information
Publications
Risk of after-hours visits to an in-hospital food animal service by speciesJeff W Tyler
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine and Surgery, University of Missouri, Columbia 65211, USA
J Vet Intern Med 20:407-9. 2006..51) and increased in South American camelidae (RR = 3.04) and sheep or goats (RR = 1.66). The likelihood of an after-hours admission differed significantly among groups...
Efficacy of different Lysigin formulations in the prevention of Staphylococcus aureus intramammary infection in dairy heifersJohn R Middleton
Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, Missouri, USA
J Dairy Res 73:10-9. 2006..aureus IMI, but Lysigin showed benefit in reducing the clinical severity and duration of clinical disease post-challenge. Neither of the experimental bacterins appeared to perform better than Lysigin...
Short communication: influence of Staphylococcus aureus intramammary infection on serum copper, zinc, and iron concentrationsJ R Middleton
Department of Veterinary Medicine and Surgery, University of Missouri, Columbia 65211, USA
J Dairy Sci 87:976-9. 2004..The reductions in trace mineral concentrations were of less magnitude than observed following experimental E. coli mastitis...
Dysautonomia and salmonellosis in an 11-year-old female llama (Lama glama)John R Middleton
Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65211, USA
J Vet Intern Med 20:213-6. 2006
Characterization of the antibody isotype response in serum and milk of heifers vaccinated with a Staphylococcus aureus bacterin (Lysigin)Christopher D Luby
Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, USA
J Dairy Res 74:239-46. 2007..aureus (P< or = 0.030). Hence, a humoural immune response to the vaccine was detected in serum and milk, but responses varied according to strain and antibody isotype tested...
Surveillance of Staphylococcus aureus in veterinary teaching hospitalsJohn R Middleton
Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65211, USA
J Clin Microbiol 43:2916-9. 2005..222). Methicillin-resistant S. aureus isolates in this study seemed to be community acquired rather than hospital acquired...
Staphylococcus aureus antigens and challenges in vaccine developmentJohn R Middleton
Department of Veterinary Medicine and Surgery, University of Missouri, 900 East Campus Drive, Columbia, MO 65211, USA
Expert Rev Vaccines 7:805-15. 2008..aureus vaccines developed have adequately prevented new infection. The antigens targeted by S. aureus vaccines and potential reasons for the lack of success of vaccination against S. aureus are reviewed in this article...
Influence of Staphylococcus aureus strain-type on mammary quarter milk somatic cell count and N-acetyl-beta-D-glucosaminidase activity in cattle from eight dairiesJ R Middleton
Department of Veterinary Medicine and Surgery, University of Missouri, Columbia 65211, USA
J Dairy Sci 85:1133-40. 2002..Overall, no significant differences were found between strains, suggesting that the degree of udder parenchymal injury induced by S. aureus IMI is in general significantly affected by factors other than strain type...
Use of pulsed-field gel electrophoresis for detecting differences in Staphylococcus aureus strain populations between dairy herds with different cattle importation practicesJ R Middleton
Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65211, USA
Epidemiol Infect 129:387-95. 2002..02). Herds that purchased replacement heifers had more total strains of Staphylococcus aureus (P = 0.01) and more new strains (P = 0.04) enter the herd than closed herds...
Technical note: Therapeutic cessation of lactation of Staphylococcus aureus-infected mammary quartersJ R Middleton
Department of Veterinary Medicine and Surgery, University of Missouri, Columbia 65211, USA
J Dairy Sci 84:1976-8. 2001..No difference in total milk production between lactation one and two in either group was found, suggesting that permanent loss of a quarter was not detrimental to overall milk production...
Efficacy of vaccination and antibiotic therapy against Staphylococcus aureus mastitis in dairy cattleC D Luby
Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65211, USA
Vet Rec 157:89-90. 2005
Prevalence of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus carriage in three populationsS Kottler
Department of Veterinary Medicine and Surgery, University of Missouri College of Veterinary Medicine, Columbia, MO, USA
J Vet Intern Med 24:132-9. 2010..A higher prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonization is reported in healthcare workers compared with nonhealthcare workers...
Escherichia coli mastitis in cattle being treated for Staphylococcus aureus intramammary infectionJ R Middleton
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
Vet Rec 162:156-7. 2008
Detection of low serum immunoglobulin concentrations in clinically ill calvesJ W Tyler
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, USA
J Vet Intern Med 13:40-3. 1999..The zinc sulfate turbidity test was inadequately specific (0.33) and resulted in misclassification of 33% of calves...
A veterinary perspective on methicillin-resistant staphylococciLeah A Cohn
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Vet Emerg Crit Care (San Antonio) 20:31-45. 2010..To familiarize the reader with the epidemiology, diagnosis, and infectious and zoonotic potential of methicillin-resistant staphylococci...
West Nile virus encephalomyelitis in a sheepJeff W Tyler
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Vet Intern Med 17:242-4. 2003
Transmissible spongiform encephalopathies in ruminantsJeff W Tyler
Department of Veterinary Medicine and Surgery, University of Missouri, 379 East Campus Drive, Columbia, MO 65211, USA
Vet Clin North Am Food Anim Pract 20:303-26, vii. 2004..Mechanisms of TSE transmission vary among host species. The diagnostic approach for TSEs of ruminants is presented,and the history and justification of regulatory programs to control and eradicate TSEs are outlined...
Effect of prepartum intramammary treatment with pirlimycin hydrochloride on prevalence of early first-lactation mastitis in dairy heifersJohn R Middleton
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 227:1969-74. 2005..CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that prepartum treatment of dairy heifers with pirlimycin may reduce the prevalence of early lactation IMI, particularly IMI caused by CNS, without causing pirlimycin residues in milk...
Enteral feeding of 3 mature cows by rumenostomyMunashe Chigerwe
Departments of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO, USA
J Vet Intern Med 19:779-81. 2005
Acanthomatous ameloblastoma of the maxilla of an adult alpacaLisa G Britt
Department of Veterinary Medicine and Surgery, University of Missouri, College of Veterinary Medicine, Clydesdale Hall 379 E Campus Drive, Columbia, MO 65211, USA
Vet Radiol Ultrasound 46:65-8. 2005..An ameloblastoma was diagnosed histologically and palliative radiation therapy was attempted. Because of poor response to therapy and anorexia the animal was euthanized. Necropsy findings confirmed an ameloblastoma of acanthomatous type...
Antigenic evaluation of a recombinant baculovirus-expressed Sarcocystis neurona SAG1 antigenG D Gupta
Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, Missouri 65211, USA
J Parasitol 90:1027-33. 2004..This is the first report of a baculovirus-expressed recombinant S. neurona antigen being used to detect anti-S. neurona antibodies in a variety of host species...
Use of somatic cell counts and California mastitis test results from individual quarter milk samples to detect subclinical intramammary infection in dairy cattle from a herd with a high bulk tank somatic cell countJohn R Middleton
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 224:419-23. 2004..CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that neither CMT score nor SCC is sensitive enough to be useful as a screening test for identifying infected mammary quarters among dairy cattle in a herd with high bulk tank SCC...
Efficacy of vaccination against staphylococcal mastitis: a review and new dataJohn R Middleton
Department of Veterinary Medicine and Surgery, University of Missouri, 900 East Campus Drive, Columbia, MO 65211, United States
Vet Microbiol 134:192-8. 2009..There may be insufficient vaccine-induced opsonizing antibody in milk to facilitate phagocytosis and clearance of staphylococci from the mammary gland...
Elimination kinetics of chlorhexidine in milk following intramammary infusion to stop lactation in mastitic mammary gland quarters of cowsJohn R Middleton
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 222:1746-9. 2003....
Diabetes mellitus in an adult alpaca (Lama pacos)J R Middleton
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
Vet Rec 157:520-2. 2005
Pharmacokinetics of intravenously administered caffeine in healthy alpacas (Lama pacos) and llamas (Lama glama)Jeffrey Lakritz
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
Am J Vet Res 67:1063-9. 2006..Intravenous administration of caffeine at a dose of 3 mg/kg did not induce clinical signs of excitement...
Theriogenology question of the month. Sertoli cell tumorChristopher D Luby
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 231:1503-5. 2007
Evaluation of a cow-side immunoassay kit for assessing IgG concentration in colostrumMunashe Chigerwe
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 227:129-31. 2005..The immunoassay kit should be useful in screening colostrum for adequate IgG concentration before feeding to calves or storage...
Pulmonary hypertension and right-sided heart failure in an adult llama with hepatic diseaseJohn R Middleton
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 228:756-9. 2006..Pulmonary hypertension secondary to hepatic disease should be considered in the differential diagnosis of right-sided heart failure...
Comparison of four methods to assess colostral IgG concentration in dairy cowsMunashe Chigerwe
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 233:761-6. 2008..To determine sensitivity and specificity of 4 methods to assess colostral IgG concentration in dairy cows and determine the optimal cutpoint for each method...
Copper toxicosis with hemolysis and hemoglobinuric nephrosis in three adult Boer goatsChantelle C Bozynski
Veterinary Medical Diagnostic Laboratory, 1600 East Rollins, Columbia, MO 65211, USA
J Vet Diagn Invest 21:395-400. 2009..Consideration also should be given to the ingestion of hepatotoxic plants and other toxic exposures, which could predispose an animal to secondary chronic copper toxicosis...
Evaluation of factors affecting serum IgG concentrations in bottle-fed calvesMunashe Chigerwe
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 234:785-9. 2009....
Effects of general anesthesia on plasma colloid oncotic pressure in dogsDavid I Dismukes
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 236:309-11. 2010..To determine the magnitude of the change in colloid oncotic pressure (COP) associated with general anesthesia in dogs undergoing a variety of elective procedures...
Effect of colostrum administration by use of oroesophageal intubation on serum IgG concentrations in Holstein bull calvesMunashe Chigerwe
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
Am J Vet Res 69:1158-63. 2008....
Frequency of detectable serum IgG concentrations in precolostral calvesMunashe Chigerwe
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
Am J Vet Res 69:791-5. 2008....
Malignant melanoma of the horn base in a Pygora goatVengai Mavangira
Department of Veterinary Medicine and Surgery, 900 East Campus Drive, Columbia, MO 65211, USA
J Vet Diagn Invest 20:104-7. 2008..The tumor cells were positive for Melan A by immunohistochemical staining...
Atypical coccidiosis in South American camelidsMunashe Chigerwe
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Vet Diagn Invest 19:122-5. 2007..This report describes 2 atypical cases of coccidiosis in South American camelids that had no coccidial oocysts detected on antemortem fecal flotation, prolonged weight loss, and normal fecal consistency...
An alternative method to assess efficiency of estrus detection in dairy herdsMunashe Chigerwe
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 226:1050-2. 2005
Effect of delayed colostrum collection on colostral IgG concentration in dairy cowsMalantus Moore
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 226:1375-7. 2005..Adjustment of routine dairy farm management procedures may be required to maximize colostrum quality and minimize prevalence of failure of passive transfer in dairy calves...
Methodology for quantifying residues of chlorhexidine in raw dairy milkVincent R Hebert
Food and Environmental Quality Laboratory, Washington State University, 2710 University Drive, Richland, Washington 99352, USA
J Agric Food Chem 51:567-70. 2003..The residue method was found to be rugged with a lower detection limit of 0.1 ppm...
