Research Topics
Species | R W MichelmoreSummaryAffiliation: University of California Country: USA Publications
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Publications
Development and application of a 6.5 million feature Affymetrix Genechip® for massively parallel discovery of single position polymorphisms in lettuce (Lactuca spp.)Kevin Stoffel
Seed Biotechnology Center, University of California Davis, CA 95616, USA
BMC Genomics 13:185. 2012....- Crop to wild introgression in lettuce: following the fate of crop genome segments in backcross populationsBrigitte Uwimana
Wageningen UR Plant Breeding, Wageningen, The Netherlands
BMC Plant Biol 12:43. 2012..Plant vigour of these two backcrossing populations was determined in the greenhouse under non-stress and abiotic stress conditions (salinity, drought, and nutrient deficiency)... - Plant NBS-LRR proteins: adaptable guardsLeah McHale
The Genome Center, University of California, Davis, CA 95616, USA
Genome Biol 7:212. 2006..Their precise role in recognition is unknown; however, they are thought to monitor the status of plant proteins that are targeted by pathogen effectors... - Association mapping and marker-assisted selection of the lettuce dieback resistance gene Tvr1Ivan Simko
United States Department of Agriculture Agricultural Research Service, Crop Improvement and Protection Research Unit, 1636 East Alisal Street, Salinas, CA 93905, USA
BMC Plant Biol 9:135. 2009..This study describes fine mapping of the resistance gene, analysis of nucleotide polymorphism and linkage disequilibrium in the Tvr1 region, and development of molecular markers for marker-assisted selection... - Global expression analysis of nucleotide binding site-leucine rich repeat-encoding and related genes in ArabidopsisXiaoping Tan
The Genome Center, University of California, Davis, California 95616, USA
BMC Plant Biol 7:56. 2007..8% of all ORFs so far annotated in Arabidopsis ecotype Col-0. Despite their prevalence in the genome and functional importance, there was little information regarding expression of these genes... - Small RNAs, DNA methylation and transposable elements in wheatDario Cantu
Department of Plant Sciences, University of California Davis, One Shields Ave, Davis, CA, USA
BMC Genomics 11:408. 2010..In this study, we report the distribution of these two types of sRNAs among the different classes of wheat TEs, the regions targeted within the TEs, and their impact on the methylation patterns of the targeted regions... - A comparison of microarray and MPSS technology platforms for expression analysis of ArabidopsisJunfeng Chen
School of Computer Science, University of Manchester, Oxford Road, Manchester, M13 9PL, UK
BMC Genomics 8:414. 2007.... 
The impact zone: genomics and breeding for durable disease resistanceRichard W Michelmore
Department of Vegetable Crops, University of California, 95616, Davis, California, USA
Curr Opin Plant Biol 6:397-404. 2003..There are, however, several biological and societal issues that will have to be resolved before the full impact of genomics on breeding for disease resistance is realized...- Clusters of resistance genes in plants evolve by divergent selection and a birth-and-death processR W Michelmore
Department of Vegetable Crops, University of California, Davis, California 95616, USA
Genome Res 8:1113-30. 1998..Intergenic unequal crossing-over and gene conversions are important but are not the primary mechanisms generating variation... - Genomic approaches to plant disease resistanceR Michelmore
Department of Vegetable Crops, University of California, Davis 95616, USA
Curr Opin Plant Biol 3:125-31. 2000..Global functional analyses will elucidate the complex regulatory networks and the diversity of proteins involved in resistance and susceptibility... - A high-density, integrated genetic linkage map of lettuce (Lactuca spp.)M J Truco
Department of Plant Sciences, University of California, Davis, CA 95616, USA
Theor Appl Genet 115:735-46. 2007..It also provides large numbers of markers for marker assisted selection, candidate gene identification, and studies of genome evolution in the Compositae... - High-density haplotyping with microarray-based expression and single feature polymorphism markers in ArabidopsisMarilyn A L West
Department of Plant Sciences, University of California Davis 95616 8780, USA
Genome Res 16:787-95. 2006..Both marker types also offer opportunities for massively parallel mapping in unsequenced and less studied species... - Genome-wide analysis of NBS-LRR-encoding genes in ArabidopsisBlake C Meyers
Department of Vegetable Crops, University of California, Davis, California 95616, USA
Plant Cell 15:809-34. 2003..The observed diversity of these NBS-LRR proteins indicates the variety of recognition molecules available in an individual genotype to detect diverse biotic challenges... 
The genomic architecture of disease resistance in lettuceLeah K McHale
The Genome Center and Department of Plant Sciences, University of California, Davis, CA 95616, USA
Theor Appl Genet 118:565-80. 2009..The majority but not all of the resistance phenotypes were genetically associated with RGCs...- Dm3 is one member of a large constitutively expressed family of nucleotide binding site-leucine-rich repeat encoding genesKatherine A Shen
Department of Vegetable Crops, University of California, Davis 95616, USA
Mol Plant Microbe Interact 15:251-61. 2002..In a wildtype Dm3-expressing genotype, many of the RGC2 family members are expressed at low levels throughout the plant... - Functional studies of the bacterial avirulence protein AvrPto by mutational analysisJ H Chang
NSF Center for Engineering Plants for Resistance Against Pathogens, University of California Davis, 95616, USA
Mol Plant Microbe Interact 14:451-9. 2001..The mutants that no longer interacted with Pto and had modified activities in planta were predicted to have changes in their secondary structure... - Plant disease resistance genes encode members of an ancient and diverse protein family within the nucleotide-binding superfamilyB C Meyers
Department of Vegetable Crops, University of California, Davis 95616, USA
Plant J 20:317-32. 1999..Sequence inferences suggest that these genes encode a novel class of nucleotide-binding proteins... - Comparative large-scale analysis of interactions between several crop species and the effector repertoires from multiple pathovars of Pseudomonas and RalstoniaTadeusz Wroblewski
Genome Center and Department of Plant Sciences, University of California, Davis, California 95616, USA
Plant Physiol 150:1733-49. 2009..Both homologous and sequence-unrelated effectors could elicit necrosis in a similar spectrum of plants, suggesting common effector targets or targeting of the same pathways in the plant cell... - Functional analysis of the plant disease resistance gene Pto using DNA shufflingAdriana J Bernal
Department of Plant Pathology, University of California, Davis, 95616, USA
J Biol Chem 280:23073-83. 2005..The correlations between phenotypes and variation generated by DNA shuffling paralleled natural variation observed between orthologs of Pto from Lycopersicon spp... - Frequent sequence exchanges between homologs of RPP8 in Arabidopsis are not necessarily associated with genomic proximityHanhui Kuang
The Genome Center and Department of Plant Sciences, University of California, Davis, CA 95616, USA
Plant J 54:69-80. 2008..Therefore, the differentiation of type I and type II RPP8 homologs seems to have occurred before speciation of A. thaliana, A. arenosa and A. lyrata... - Genomic survey of gene expression diversity in Arabidopsis thalianaDaniel J Kliebenstein
Department of Plant Sciences, University of California, Davis, California 95616-8780, USA
Genetics 172:1179-89. 2006..Examination of sequence diversity demonstrated a significant positive association with diversity in gene expression... - Functional analyses of the Pto resistance gene family in tomato and the identification of a minor resistance determinant in a susceptible haplotypeJeff H Chang
NSF Center for Engineering Plants for Resistance Against Pathogens, University of California, Davis, 95616 USA
Mol Plant Microbe Interact 15:281-91. 2002..LescPth5 induced cell death specifically in response to expression of AvrPto in tobacco in a Prf-dependent manner; this is consistent with a homolog from a 'susceptible' haplotype encoding a minor recognition determinant... - TIR-X and TIR-NBS proteins: two new families related to disease resistance TIR-NBS-LRR proteins encoded in Arabidopsis and other plant genomesBlake C Meyers
Department of Vegetable Crops, University of California, Davis, CA 95616, USA
Plant J 32:77-92. 2002..These TX and TN proteins could be plant analogues of small TIR-adapter proteins that function in mammalian innate immune responses such as MyD88 and Mal... - The maintenance of extreme amino acid diversity at the disease resistance gene, RPP13, in Arabidopsis thalianaLaura E Rose
Center for Population Biology, University of California, Davis, California 95616, USA
Genetics 166:1517-27. 2004.... - Quantitative trait loci associated with seed and seedling traits in LactucaJason Argyris
Department of Plant Sciences, University of California, Davis, CA 95616-8780, USA
Theor Appl Genet 111:1365-76. 2005..serriola alleles increased germination at these QTL. The estimate of narrow-sense heritability (h2) of Htg6.1 was 0.84, indicating potential for L. serriola as a source of germination thermotolerance for lettuce introgression programs... - Silencing of the major family of NBS-LRR-encoding genes in lettuce results in the loss of multiple resistance specificitiesTadeusz Wroblewski
The Genome Center, University of California in Davis, Davis, CA 95616, USA
Plant J 51:803-18. 2007..lactucae, Dm14 and Dm16, as well as resistance to lettuce root aphid (Pemphigus bursarius L.), Ra, are encoded by RGC2 family members... - The disease resistance gene Dm3 is infrequent in natural populations of Lactuca serriola due to deletions and frequent gene conversions at the RGC2 locusHanhui Kuang
Department of Plant Science and Genome Center, University of California, Davis, CA 95616, USA
Plant J 47:38-48. 2006..This has implications for the scales of germplasm conservation and exploitation of sources of resistance... - A genetic map of the lettuce downy mildew pathogen, Bremia lactucae, constructed from molecular markers and avirulence genesDelphine Sicard
Department of Vegetable Crops, University of California Davis, CA 94720, USA
Fungal Genet Biol 39:16-30. 2003..Mating type seemed to be determined by a single locus, where the heterozygote determined the B(2) type and the homozygous recessive genotype determined the B(1) type... - Arabidopsis thaliana genes encoding defense signaling and recognition proteins exhibit contrasting evolutionary dynamicsKatherine S Caldwell
The Genome Center, University of California, Davis, California 95616, USA
Genetics 181:671-84. 2009.... - Multiple genetic processes result in heterogeneous rates of evolution within the major cluster disease resistance genes in lettuceHanhui Kuang
Department of Vegetable Crops, University of California, Davis, California 95616, USA
Plant Cell 16:2870-94. 2004..Unequal crossover, insertion/deletion, and point mutation events were distributed unequally through the gene. Different evolutionary forces have impacted different parts of the LRR... - avrPto enhances growth and necrosis caused by Pseudomonas syringae pv.tomato in tomato lines lacking either Pto or PrfJ H Chang
NSF Center for Engineering Plants for Resistance Against Pathogens, University of California, Davis, 95616, USA
Mol Plant Microbe Interact 13:568-71. 2000..The enhanced necrosis correlated with a small increase in bacterial growth. In planta expression of avrPto in isolation did not elicit necrosis in the absence of a functional Prf gene... - Global eQTL mapping reveals the complex genetic architecture of transcript-level variation in ArabidopsisMarilyn A L West
Department of Plant Sciences, University of California, Davis, California 95616 8780, USA
Genetics 175:1441-50. 2007..It reveals that the genetic control of transcript level is highly variable and multifaceted and that this complexity may be a general characteristic of eukaryotes... - Natural variation among Arabidopsis thaliana accessions for transcriptome response to exogenous salicylic acidHans van Leeuwen
Department of Plant Sciences, University of California, Davis, California 95616, USA
Plant Cell 19:2099-110. 2007..Expression level polymorphisms for SA response were abundant at both individual gene and gene-network levels in the seven accessions, suggesting that natural variation for SA response is prevalent in Arabidopsis... - Natural variation in the Pto disease resistance gene within species of wild tomato (Lycopersicon). II. Population genetics of PtoLaura E Rose
The Center for Population Biology, University of California, Davis, California 95616
Genetics 175:1307-19. 2007..Therefore, the evolution of Pto appears to be influenced by a mixture of both purifying and balancing selection... - Transgene-induced gene silencing is not affected by a change in ploidy levelDaniela Pignatta
Department of Plant Biology and Genome Center, University of California Davis, Davis, California, United States of America
PLoS ONE 3:e3061. 2008..Here, we tested the hypothesis that an increase in ploidy enhances transgene-induced post-transcriptional gene silencing using autopolyploids of A. thaliana... - Natural variation in the Pto pathogen resistance gene within species of wild tomato (Lycopersicon). I. Functional analysis of Pto allelesLaura E Rose
Center for Population Biology, University of California, Davis, California 95616, USA
Genetics 171:345-57. 2005..Therefore, a large proportion, but not all, of the natural variation in the reaction to strains of Pst expressing AvrPto can be attributed to sequence variation in the Pto gene... - Patterns of positive selection in the complete NBS-LRR gene family of Arabidopsis thalianaMariana Mondragon-Palomino
Department of Ecology and Evolutionary Biology, University of California Irvine, Irvine, California 92612, USA
Genome Res 12:1305-15. 2002..LRRs also contain substantial indel variation, suggesting elasticity in LRR length could also influence resistance specificity... - Genetic diversity and genomic distribution of homologs encoding NBS-LRR disease resistance proteins in sunflowerOsman Radwan
Center for Applied Genetic Technologies, The University of Georgia, 111 Riverbend Road, Athens, GA 30602, USA
Mol Genet Genomics 280:111-25. 2008..Sunflower nucleotide and amino acid sequences have been deposited in DDBJ/EMBL/GenBank under accession numbers EF 560168-EF 559378 and ABQ 58077-ABQ 57529... - Discovery of ADP-ribosylation and other plant defense pathway elements through expression profiling of four different Arabidopsis-Pseudomonas R-avr interactionsLori Adams-Phillips
Department of Plant Pathology, University of Wisconsin Madison, Madison, WI 53706, USA
Mol Plant Microbe Interact 21:646-57. 2008.... - Using variable rate models to identify genes under selection in sequence pairs: their validity and limitations for EST sequencesSheri A Church
Department of Biology, Indiana University, Bloomington, IN 47405, USA
J Mol Evol 64:171-80. 2007..We discuss the validity and limitations of using variable rate models for comparisons of sequence pairs, as well as the limitations of using ESTs for identification of positively selected genes... - SNP-based codominant markers for a recessive gene conferring resistance to corky root rot (Rhizomonas suberifaciens) in lettuce (Lactuca sativa)Santiago Moreno-Vázquez
Departamento de Biologia Vegetal, E T S Ingenieros Agronomos, Universidad Poltécnica de Madrid, Ciudad Universitaria, Madrid, Spain
Genome 46:1059-69. 2003..Evaluation of these markers in a large sample of cultivars and landraces identified pairs of flanking polymorphic markers that can be used for marker-assisted selection of corky root resistance...