R W Michelmore

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint The impact zone: genomics and breeding for durable disease resistance
    Richard W Michelmore
    Department of Vegetable Crops, University of California, 95616, Davis, California, USA
    Curr Opin Plant Biol 6:397-404. 2003
  2. pmc Consequences of normalizing transcriptomic and genomic libraries of plant genomes using a duplex-specific nuclease and tetramethylammonium chloride
    Marta Matvienko
    Genome Center, University of California Davis, Davis, California, USA
    PLoS ONE 8:e55913. 2013
  3. doi request reprint Impacts of resistance gene genetics, function, and evolution on a durable future
    Richard W Michelmore
    The Genome Center, University of California, Davis, California 95616, USA
    Annu Rev Phytopathol 51:291-319. 2013
  4. pmc Development and application of a 6.5 million feature Affymetrix Genechip® for massively parallel discovery of single position polymorphisms in lettuce (Lactuca spp.)
    Kevin Stoffel
    Seed Biotechnology Center, University of California Davis, CA 95616, USA
    BMC Genomics 13:185. 2012
  5. pmc Crop to wild introgression in lettuce: following the fate of crop genome segments in backcross populations
    Brigitte Uwimana
    Wageningen UR Plant Breeding, Wageningen, The Netherlands
    BMC Plant Biol 12:43. 2012
  6. pmc Plant NBS-LRR proteins: adaptable guards
    Leah McHale
    The Genome Center, University of California, Davis, CA 95616, USA
    Genome Biol 7:212. 2006
  7. pmc Association mapping and marker-assisted selection of the lettuce dieback resistance gene Tvr1
    Ivan Simko
    United States Department of Agriculture Agricultural Research Service, Crop Improvement and Protection Research Unit, 1636 East Alisal Street, Salinas, CA 93905, USA
    BMC Plant Biol 9:135. 2009
  8. pmc Global expression analysis of nucleotide binding site-leucine rich repeat-encoding and related genes in Arabidopsis
    Xiaoping Tan
    The Genome Center, University of California, Davis, California 95616, USA
    BMC Plant Biol 7:56. 2007
  9. pmc Small RNAs, DNA methylation and transposable elements in wheat
    Dario Cantu
    Department of Plant Sciences, University of California Davis, One Shields Ave, Davis, CA, USA
    BMC Genomics 11:408. 2010
  10. pmc A comparison of microarray and MPSS technology platforms for expression analysis of Arabidopsis
    Junfeng Chen
    School of Computer Science, University of Manchester, Oxford Road, Manchester, M13 9PL, UK
    BMC Genomics 8:414. 2007

Collaborators

Detail Information

Publications44

  1. ncbi request reprint The impact zone: genomics and breeding for durable disease resistance
    Richard W Michelmore
    Department of Vegetable Crops, University of California, 95616, Davis, California, USA
    Curr Opin Plant Biol 6:397-404. 2003
    ..There are, however, several biological and societal issues that will have to be resolved before the full impact of genomics on breeding for disease resistance is realized...
  2. pmc Consequences of normalizing transcriptomic and genomic libraries of plant genomes using a duplex-specific nuclease and tetramethylammonium chloride
    Marta Matvienko
    Genome Center, University of California Davis, Davis, California, USA
    PLoS ONE 8:e55913. 2013
    ..Consequences of this method on the reduction of high-copy and enrichment of low-copy sequences are reported for Arabidopsis and lettuce...
  3. doi request reprint Impacts of resistance gene genetics, function, and evolution on a durable future
    Richard W Michelmore
    The Genome Center, University of California, Davis, California 95616, USA
    Annu Rev Phytopathol 51:291-319. 2013
    ....
  4. pmc Development and application of a 6.5 million feature Affymetrix Genechip® for massively parallel discovery of single position polymorphisms in lettuce (Lactuca spp.)
    Kevin Stoffel
    Seed Biotechnology Center, University of California Davis, CA 95616, USA
    BMC Genomics 13:185. 2012
    ....
  5. pmc Crop to wild introgression in lettuce: following the fate of crop genome segments in backcross populations
    Brigitte Uwimana
    Wageningen UR Plant Breeding, Wageningen, The Netherlands
    BMC Plant Biol 12:43. 2012
    ..Plant vigour of these two backcrossing populations was determined in the greenhouse under non-stress and abiotic stress conditions (salinity, drought, and nutrient deficiency)...
  6. pmc Plant NBS-LRR proteins: adaptable guards
    Leah McHale
    The Genome Center, University of California, Davis, CA 95616, USA
    Genome Biol 7:212. 2006
    ..Their precise role in recognition is unknown; however, they are thought to monitor the status of plant proteins that are targeted by pathogen effectors...
  7. pmc Association mapping and marker-assisted selection of the lettuce dieback resistance gene Tvr1
    Ivan Simko
    United States Department of Agriculture Agricultural Research Service, Crop Improvement and Protection Research Unit, 1636 East Alisal Street, Salinas, CA 93905, USA
    BMC Plant Biol 9:135. 2009
    ..This study describes fine mapping of the resistance gene, analysis of nucleotide polymorphism and linkage disequilibrium in the Tvr1 region, and development of molecular markers for marker-assisted selection...
  8. pmc Global expression analysis of nucleotide binding site-leucine rich repeat-encoding and related genes in Arabidopsis
    Xiaoping Tan
    The Genome Center, University of California, Davis, California 95616, USA
    BMC Plant Biol 7:56. 2007
    ..8% of all ORFs so far annotated in Arabidopsis ecotype Col-0. Despite their prevalence in the genome and functional importance, there was little information regarding expression of these genes...
  9. pmc Small RNAs, DNA methylation and transposable elements in wheat
    Dario Cantu
    Department of Plant Sciences, University of California Davis, One Shields Ave, Davis, CA, USA
    BMC Genomics 11:408. 2010
    ..In this study, we report the distribution of these two types of sRNAs among the different classes of wheat TEs, the regions targeted within the TEs, and their impact on the methylation patterns of the targeted regions...
  10. pmc A comparison of microarray and MPSS technology platforms for expression analysis of Arabidopsis
    Junfeng Chen
    School of Computer Science, University of Manchester, Oxford Road, Manchester, M13 9PL, UK
    BMC Genomics 8:414. 2007
    ....
  11. ncbi request reprint Clusters of resistance genes in plants evolve by divergent selection and a birth-and-death process
    R W Michelmore
    Department of Vegetable Crops, University of California, Davis, California 95616, USA
    Genome Res 8:1113-30. 1998
    ..Intergenic unequal crossing-over and gene conversions are important but are not the primary mechanisms generating variation...
  12. ncbi request reprint Genomic approaches to plant disease resistance
    R Michelmore
    Department of Vegetable Crops, University of California, Davis 95616, USA
    Curr Opin Plant Biol 3:125-31. 2000
    ..Global functional analyses will elucidate the complex regulatory networks and the diversity of proteins involved in resistance and susceptibility...
  13. ncbi request reprint Dm3 is one member of a large constitutively expressed family of nucleotide binding site-leucine-rich repeat encoding genes
    Katherine A Shen
    Department of Vegetable Crops, University of California, Davis 95616, USA
    Mol Plant Microbe Interact 15:251-61. 2002
    ..In a wildtype Dm3-expressing genotype, many of the RGC2 family members are expressed at low levels throughout the plant...
  14. pmc High-density haplotyping with microarray-based expression and single feature polymorphism markers in Arabidopsis
    Marilyn A L West
    Department of Plant Sciences, University of California Davis 95616 8780, USA
    Genome Res 16:787-95. 2006
    ..Both marker types also offer opportunities for massively parallel mapping in unsequenced and less studied species...
  15. doi request reprint The genomic architecture of disease resistance in lettuce
    Leah K McHale
    The Genome Center and Department of Plant Sciences, University of California, Davis, CA 95616, USA
    Theor Appl Genet 118:565-80. 2009
    ..The majority but not all of the resistance phenotypes were genetically associated with RGCs...
  16. pmc Genome-wide analysis of NBS-LRR-encoding genes in Arabidopsis
    Blake C Meyers
    Department of Vegetable Crops, University of California, Davis, California 95616, USA
    Plant Cell 15:809-34. 2003
    ..The observed diversity of these NBS-LRR proteins indicates the variety of recognition molecules available in an individual genotype to detect diverse biotic challenges...
  17. ncbi request reprint Plant disease resistance genes encode members of an ancient and diverse protein family within the nucleotide-binding superfamily
    B C Meyers
    Department of Vegetable Crops, University of California, Davis 95616, USA
    Plant J 20:317-32. 1999
    ..Sequence inferences suggest that these genes encode a novel class of nucleotide-binding proteins...
  18. ncbi request reprint Functional studies of the bacterial avirulence protein AvrPto by mutational analysis
    J H Chang
    NSF Center for Engineering Plants for Resistance Against Pathogens, University of California Davis, 95616, USA
    Mol Plant Microbe Interact 14:451-9. 2001
    ..The mutants that no longer interacted with Pto and had modified activities in planta were predicted to have changes in their secondary structure...
  19. doi request reprint Frequent sequence exchanges between homologs of RPP8 in Arabidopsis are not necessarily associated with genomic proximity
    Hanhui Kuang
    The Genome Center and Department of Plant Sciences, University of California, Davis, CA 95616, USA
    Plant J 54:69-80. 2008
    ..Therefore, the differentiation of type I and type II RPP8 homologs seems to have occurred before speciation of A. thaliana, A. arenosa and A. lyrata...
  20. ncbi request reprint TIR-X and TIR-NBS proteins: two new families related to disease resistance TIR-NBS-LRR proteins encoded in Arabidopsis and other plant genomes
    Blake C Meyers
    Department of Vegetable Crops, University of California, Davis, CA 95616, USA
    Plant J 32:77-92. 2002
    ..These TX and TN proteins could be plant analogues of small TIR-adapter proteins that function in mammalian innate immune responses such as MyD88 and Mal...
  21. ncbi request reprint Functional analyses of the Pto resistance gene family in tomato and the identification of a minor resistance determinant in a susceptible haplotype
    Jeff H Chang
    NSF Center for Engineering Plants for Resistance Against Pathogens, University of California, Davis, 95616 USA
    Mol Plant Microbe Interact 15:281-91. 2002
    ..LescPth5 induced cell death specifically in response to expression of AvrPto in tobacco in a Prf-dependent manner; this is consistent with a homolog from a 'susceptible' haplotype encoding a minor recognition determinant...
  22. pmc Comparative large-scale analysis of interactions between several crop species and the effector repertoires from multiple pathovars of Pseudomonas and Ralstonia
    Tadeusz Wroblewski
    Genome Center and Department of Plant Sciences, University of California, Davis, California 95616, USA
    Plant Physiol 150:1733-49. 2009
    ..Both homologous and sequence-unrelated effectors could elicit necrosis in a similar spectrum of plants, suggesting common effector targets or targeting of the same pathways in the plant cell...
  23. pmc Genomic survey of gene expression diversity in Arabidopsis thaliana
    Daniel J Kliebenstein
    Department of Plant Sciences, University of California, Davis, California 95616 8780, USA
    Genetics 172:1179-89. 2006
    ..Examination of sequence diversity demonstrated a significant positive association with diversity in gene expression...
  24. pmc The maintenance of extreme amino acid diversity at the disease resistance gene, RPP13, in Arabidopsis thaliana
    Laura E Rose
    Center for Population Biology, University of California, Davis, California 95616, USA
    Genetics 166:1517-27. 2004
    ....
  25. ncbi request reprint Functional analysis of the plant disease resistance gene Pto using DNA shuffling
    Adriana J Bernal
    Department of Plant Pathology, University of California, Davis, 95616, USA
    J Biol Chem 280:23073-83. 2005
    ..The correlations between phenotypes and variation generated by DNA shuffling paralleled natural variation observed between orthologs of Pto from Lycopersicon spp...
  26. ncbi request reprint Quantitative trait loci associated with seed and seedling traits in Lactuca
    Jason Argyris
    Department of Plant Sciences, University of California, Davis, CA 95616 8780, USA
    Theor Appl Genet 111:1365-76. 2005
    ..serriola alleles increased germination at these QTL. The estimate of narrow-sense heritability (h2) of Htg6.1 was 0.84, indicating potential for L. serriola as a source of germination thermotolerance for lettuce introgression programs...
  27. ncbi request reprint A genetic map of the lettuce downy mildew pathogen, Bremia lactucae, constructed from molecular markers and avirulence genes
    Delphine Sicard
    Department of Vegetable Crops, University of California Davis, CA 94720, USA
    Fungal Genet Biol 39:16-30. 2003
    ..Mating type seemed to be determined by a single locus, where the heterozygote determined the B(2) type and the homozygous recessive genotype determined the B(1) type...
  28. pmc Multiple genetic processes result in heterogeneous rates of evolution within the major cluster disease resistance genes in lettuce
    Hanhui Kuang
    Department of Vegetable Crops, University of California, Davis, California 95616, USA
    Plant Cell 16:2870-94. 2004
    ..Unequal crossover, insertion/deletion, and point mutation events were distributed unequally through the gene. Different evolutionary forces have impacted different parts of the LRR...
  29. pmc Arabidopsis thaliana genes encoding defense signaling and recognition proteins exhibit contrasting evolutionary dynamics
    Katherine S Caldwell
    The Genome Center, University of California, Davis, California 95616, USA
    Genetics 181:671-84. 2009
    ....
  30. ncbi request reprint The disease resistance gene Dm3 is infrequent in natural populations of Lactuca serriola due to deletions and frequent gene conversions at the RGC2 locus
    Hanhui Kuang
    Department of Plant Science and Genome Center, University of California, Davis, CA 95616, USA
    Plant J 47:38-48. 2006
    ..This has implications for the scales of germplasm conservation and exploitation of sources of resistance...
  31. ncbi request reprint Silencing of the major family of NBS-LRR-encoding genes in lettuce results in the loss of multiple resistance specificities
    Tadeusz Wroblewski
    The Genome Center, University of California in Davis, Davis, CA 95616, USA
    Plant J 51:803-18. 2007
    ..lactucae, Dm14 and Dm16, as well as resistance to lettuce root aphid (Pemphigus bursarius L.), Ra, are encoded by RGC2 family members...
  32. ncbi request reprint A high-density, integrated genetic linkage map of lettuce (Lactuca spp.)
    M J Truco
    Department of Plant Sciences, University of California, Davis, CA 95616, USA
    Theor Appl Genet 115:735-46. 2007
    ..It also provides large numbers of markers for marker assisted selection, candidate gene identification, and studies of genome evolution in the Compositae...
  33. ncbi request reprint avrPto enhances growth and necrosis caused by Pseudomonas syringae pv.tomato in tomato lines lacking either Pto or Prf
    J H Chang
    NSF Center for Engineering Plants for Resistance Against Pathogens, University of California, Davis, 95616, USA
    Mol Plant Microbe Interact 13:568-71. 2000
    ..The enhanced necrosis correlated with a small increase in bacterial growth. In planta expression of avrPto in isolation did not elicit necrosis in the absence of a functional Prf gene...
  34. pmc Global eQTL mapping reveals the complex genetic architecture of transcript-level variation in Arabidopsis
    Marilyn A L West
    Department of Plant Sciences, University of California, Davis, California 95616 8780, USA
    Genetics 175:1441-50. 2007
    ..It reveals that the genetic control of transcript level is highly variable and multifaceted and that this complexity may be a general characteristic of eukaryotes...
  35. pmc Natural variation in the Pto disease resistance gene within species of wild tomato (Lycopersicon). II. Population genetics of Pto
    Laura E Rose
    The Center for Population Biology, University of California, Davis, California 95616
    Genetics 175:1307-19. 2007
    ..Therefore, the evolution of Pto appears to be influenced by a mixture of both purifying and balancing selection...
  36. pmc Natural variation among Arabidopsis thaliana accessions for transcriptome response to exogenous salicylic acid
    Hans van Leeuwen
    Department of Plant Sciences, University of California, Davis, California 95616, USA
    Plant Cell 19:2099-110. 2007
    ..Expression level polymorphisms for SA response were abundant at both individual gene and gene-network levels in the seven accessions, suggesting that natural variation for SA response is prevalent in Arabidopsis...
  37. pmc Natural variation in the Pto pathogen resistance gene within species of wild tomato (Lycopersicon). I. Functional analysis of Pto alleles
    Laura E Rose
    Center for Population Biology, University of California, Davis, California 95616, USA
    Genetics 171:345-57. 2005
    ..Therefore, a large proportion, but not all, of the natural variation in the reaction to strains of Pst expressing AvrPto can be attributed to sequence variation in the Pto gene...
  38. pmc Transgene-induced gene silencing is not affected by a change in ploidy level
    Daniela Pignatta
    Department of Plant Biology and Genome Center, University of California Davis, Davis, California, United States of America
    PLoS ONE 3:e3061. 2008
    ..Here, we tested the hypothesis that an increase in ploidy enhances transgene-induced post-transcriptional gene silencing using autopolyploids of A. thaliana...
  39. pmc Patterns of positive selection in the complete NBS-LRR gene family of Arabidopsis thaliana
    Mariana Mondragon-Palomino
    Department of Ecology and Evolutionary Biology, University of California Irvine, Irvine, California 92612, USA
    Genome Res 12:1305-15. 2002
    ..LRRs also contain substantial indel variation, suggesting elasticity in LRR length could also influence resistance specificity...
  40. doi request reprint Genetic diversity and genomic distribution of homologs encoding NBS-LRR disease resistance proteins in sunflower
    Osman Radwan
    Center for Applied Genetic Technologies, The University of Georgia, 111 Riverbend Road, Athens, GA 30602, USA
    Mol Genet Genomics 280:111-25. 2008
    ..Sunflower nucleotide and amino acid sequences have been deposited in DDBJ/EMBL/GenBank under accession numbers EF 560168-EF 559378 and ABQ 58077-ABQ 57529...
  41. doi request reprint Discovery of ADP-ribosylation and other plant defense pathway elements through expression profiling of four different Arabidopsis-Pseudomonas R-avr interactions
    Lori Adams-Phillips
    Department of Plant Pathology, University of Wisconsin Madison, Madison, WI 53706, USA
    Mol Plant Microbe Interact 21:646-57. 2008
    ....
  42. ncbi request reprint Using variable rate models to identify genes under selection in sequence pairs: their validity and limitations for EST sequences
    Sheri A Church
    Department of Biology, Indiana University, Bloomington, IN 47405, USA
    J Mol Evol 64:171-80. 2007
    ..We discuss the validity and limitations of using variable rate models for comparisons of sequence pairs, as well as the limitations of using ESTs for identification of positively selected genes...
  43. ncbi request reprint SNP-based codominant markers for a recessive gene conferring resistance to corky root rot (Rhizomonas suberifaciens) in lettuce (Lactuca sativa)
    Santiago Moreno-Vázquez
    Departamento de Biologia Vegetal, E T S Ingenieros Agronomos, Universidad Poltécnica de Madrid, Ciudad Universitaria, Madrid, Spain
    Genome 46:1059-69. 2003
    ..Evaluation of these markers in a large sample of cultivars and landraces identified pairs of flanking polymorphic markers that can be used for marker-assisted selection of corky root resistance...