Anushka Michailova

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Numerical analysis of Ca2+ signaling in rat ventricular myocytes with realistic transverse-axial tubular geometry and inhibited sarcoplasmic reticulum
    Yuhui Cheng
    Department of Bioengineering, University of California San Diego, La Jolla, California, United States of America
    PLoS Comput Biol 6:e1000972. 2010
  2. ncbi request reprint Effects of magnesium on cardiac excitation-contraction coupling
    Anushka P Michailova
    Department of Bioengineering, PFBH 241, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0412, USA
    J Am Coll Nutr 23:514S-517S. 2004
  3. pmc Modeling regulation of cardiac KATP and L-type Ca2+ currents by ATP, ADP, and Mg2+
    Anushka Michailova
    Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA
    Biophys J 88:2234-49. 2005
  4. ncbi request reprint Modeling transmural heterogeneity of K(ATP) current in rabbit ventricular myocytes
    Anushka Michailova
    Dept of Bioengineering, PFBH 241, University of California San Diego, La Jolla, CA 92093 0412, USA
    Am J Physiol Cell Physiol 293:C542-57. 2007
  5. ncbi request reprint Effects of Mg2+, pH and PCr on cardiac excitation-metabolic coupling
    Anushka Michailova
    Department of Bioengineering, PFBH 241, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0412, USA
    Magnes Res 21:16-28. 2008
  6. pmc Multiscale modeling in rodent ventricular myocytes
    Shaoying Lu
    Department of Bioengineering, University of California San Diego, La Jolla, 92093 0412, USA
    IEEE Eng Med Biol Mag 28:46-57. 2009
  7. pmc Sensitivity of rabbit ventricular action potential and Ca²⁺ dynamics to small variations in membrane currents and ion diffusion coefficients
    Yuan Hung Lo
    Department of Bioengineering, PFBH 241, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0412, USA
    Biomed Res Int 2013:565431. 2013
  8. pmc Spatiotemporal features of Ca2+ buffering and diffusion in atrial cardiac myocytes with inhibited sarcoplasmic reticulum
    Anushka Michailova
    Department of Physiology, University of Bern, Buehlplatz 5, CH 3012 Bern, Switzerland
    Biophys J 83:3134-51. 2002

Collaborators

Detail Information

Publications8

  1. pmc Numerical analysis of Ca2+ signaling in rat ventricular myocytes with realistic transverse-axial tubular geometry and inhibited sarcoplasmic reticulum
    Yuhui Cheng
    Department of Bioengineering, University of California San Diego, La Jolla, California, United States of America
    PLoS Comput Biol 6:e1000972. 2010
    ..The model predicts that the branched t-tubule structure and changes in the normal Ca(2+) flux density along the cell membrane support initiation and propagation of Ca(2+) waves in rat myocytes...
  2. ncbi request reprint Effects of magnesium on cardiac excitation-contraction coupling
    Anushka P Michailova
    Department of Bioengineering, PFBH 241, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0412, USA
    J Am Coll Nutr 23:514S-517S. 2004
    ..Small changes in intracellular free Mg(2+) ([Mg(2+)](i)) may have important effects on cardiac excitability and contractility. We investigated the effects of [Mg(2+)](i) on cardiac excitation-contraction coupling...
  3. pmc Modeling regulation of cardiac KATP and L-type Ca2+ currents by ATP, ADP, and Mg2+
    Anushka Michailova
    Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA
    Biophys J 88:2234-49. 2005
    ..The model predictions are in agreement with experimental data measured under normal and a variety of pathological conditions...
  4. ncbi request reprint Modeling transmural heterogeneity of K(ATP) current in rabbit ventricular myocytes
    Anushka Michailova
    Dept of Bioengineering, PFBH 241, University of California San Diego, La Jolla, CA 92093 0412, USA
    Am J Physiol Cell Physiol 293:C542-57. 2007
    ..The model predictions are in qualitative agreement with experimental data measured under normal and ischemic conditions in rabbit ventricular myocytes...
  5. ncbi request reprint Effects of Mg2+, pH and PCr on cardiac excitation-metabolic coupling
    Anushka Michailova
    Department of Bioengineering, PFBH 241, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0412, USA
    Magnes Res 21:16-28. 2008
    ..The model reproduces qualitatively a sequence of events that correlates well with the experimental data...
  6. pmc Multiscale modeling in rodent ventricular myocytes
    Shaoying Lu
    Department of Bioengineering, University of California San Diego, La Jolla, 92093 0412, USA
    IEEE Eng Med Biol Mag 28:46-57. 2009
    ..Subsequent studies have demonstrated that the t-tubular system has also longitudinal extensions [9]--[11], [13]...
  7. pmc Sensitivity of rabbit ventricular action potential and Ca²⁺ dynamics to small variations in membrane currents and ion diffusion coefficients
    Yuan Hung Lo
    Department of Bioengineering, PFBH 241, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0412, USA
    Biomed Res Int 2013:565431. 2013
    ..model. Our results demonstrate usefulness of sensitivity analysis to identify specific knowledge gaps and controversies related to ventricular cell electrophysiology and Ca²⁺ signaling...
  8. pmc Spatiotemporal features of Ca2+ buffering and diffusion in atrial cardiac myocytes with inhibited sarcoplasmic reticulum
    Anushka Michailova
    Department of Physiology, University of Bern, Buehlplatz 5, CH 3012 Bern, Switzerland
    Biophys J 83:3134-51. 2002
    ..In addition, the computations revealed that, despite its low Ca(2+) affinity, ATP acts as a significant buffer and carrier for Ca(2+), even at the modest elevations of [Ca(2+)](i) reached during influx of Ca(2+)...