Research Topics
| Anushka MichailovaSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Effects of magnesium on cardiac excitation-contraction couplingAnushka P Michailova
Department of Bioengineering, PFBH 241, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0412, USA
J Am Coll Nutr 23:514S-517S. 2004..Small changes in intracellular free Mg(2+) ([Mg(2+)](i)) may have important effects on cardiac excitability and contractility. We investigated the effects of [Mg(2+)](i) on cardiac excitation-contraction coupling...
Modeling regulation of cardiac KATP and L-type Ca2+ currents by ATP, ADP, and Mg2+Anushka Michailova
Department of Bioengineering, University of California San Diego, La Jolla, CA 92093, USA
Biophys J 88:2234-49. 2005..The model predictions are in agreement with experimental data measured under normal and a variety of pathological conditions...
Modeling transmural heterogeneity of K(ATP) current in rabbit ventricular myocytesAnushka Michailova
Dept of Bioengineering, PFBH 241, University of California San Diego, La Jolla, CA 92093 0412, USA
Am J Physiol Cell Physiol 293:C542-57. 2007..The model predictions are in qualitative agreement with experimental data measured under normal and ischemic conditions in rabbit ventricular myocytes...
Effects of Mg2+, pH and PCr on cardiac excitation-metabolic couplingAnushka Michailova
Department of Bioengineering, PFBH 241, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0412, USA
Magnes Res 21:16-28. 2008..The model reproduces qualitatively a sequence of events that correlates well with the experimental data...
Multiscale modeling in rodent ventricular myocytesShaoying Lu
Department of Bioengineering, University of California San Diego, La Jolla, 92093 0412, USA
IEEE Eng Med Biol Mag 28:46-57. 2009..Subsequent studies have demonstrated that the t-tubular system has also longitudinal extensions [9]--[11], [13]...
Spatiotemporal features of Ca2+ buffering and diffusion in atrial cardiac myocytes with inhibited sarcoplasmic reticulumAnushka Michailova
Department of Physiology, University of Bern, Buehlplatz 5, CH 3012 Bern, Switzerland
Biophys J 83:3134-51. 2002..In addition, the computations revealed that, despite its low Ca(2+) affinity, ATP acts as a significant buffer and carrier for Ca(2+), even at the modest elevations of [Ca(2+)](i) reached during influx of Ca(2+)...
