Yubin Miao

Summary

Affiliation: University of New Mexico
Country: USA

Publications

  1. ncbi Peptide-targeted radionuclide therapy for melanoma
    Yubin Miao
    College of Pharmacy, University of New Mexico, 2502 Marble NE, MSC09 5360, Albuquerque, NM 87131, USA
    Crit Rev Oncol Hematol 67:213-28. 2008
  2. ncbi 203Pb-labeled alpha-melanocyte-stimulating hormone peptide as an imaging probe for melanoma detection
    Yubin Miao
    Department of Dermatology, University of New Mexico, Albuquerque, New Mexico 87131, USA
    J Nucl Med 49:823-9. 2008
  3. ncbi 111In-labeled lactam bridge-cyclized alpha-melanocyte stimulating hormone peptide analogues for melanoma imaging
    Yubin Miao
    College of Pharmacy, University of New Mexico, Albuquerque, New Mexico 87131, USA
    Bioconjug Chem 19:539-47. 2008
  4. ncbi Alpha-melanocyte stimulating hormone peptide-targeted melanoma imaging
    Yubin Miao
    College of Pharmacy, University of New Mexico, Albuquerque, NM 87131 0001, USA
    Front Biosci 12:4514-24. 2007
  5. ncbi Reducing renal uptake of 90Y- and 177Lu-labeled alpha-melanocyte stimulating hormone peptide analogues
    Yubin Miao
    Department of Internal Medicine, University of Missouri Columbia, Columbia, MO 65211, USA
    Nucl Med Biol 33:723-33. 2006
  6. ncbi Evaluation of the human melanoma targeting properties of radiolabeled alpha-melanocyte stimulating hormone peptide analogues
    Yubin Miao
    Department of Biochemistry, University of Missouri-Columbia, Columbia, Missouri 65211, USA
    Bioconjug Chem 14:1177-84. 2003
  7. ncbi Effect of DOTA position on melanoma targeting and pharmacokinetic properties of 111In-labeled lactam bridge-cyclized alpha-melanocyte stimulating hormone peptide
    Haixun Guo
    College of Pharmacy, Cancer Research Treatment Center, Department of Cell Biology and Physiology, Department of Pathology, Department of Dermatology, University of New Mexico, Albuquerque, New Mexico 87131, USA
    Bioconjug Chem 20:2162-8. 2009
  8. ncbi Reduction of the ring size of radiolabeled lactam bridge-cyclized alpha-MSH peptide, resulting in enhanced melanoma uptake
    Haixun Guo
    College of Pharmacy, University of New Mexico, Albuquerque, New Mexico 87131, USA
    J Nucl Med 51:418-26. 2010
  9. ncbi Therapeutic efficacy of a 188Re-labeled alpha-melanocyte-stimulating hormone peptide analog in murine and human melanoma-bearing mouse models
    Yubin Miao
    Department of Biochemistry, University of Missouri-Columbia, Columbia, MO 65211, USA
    J Nucl Med 46:121-9. 2005
  10. ncbi Metastatic melanoma imaging with an (111)In-labeled lactam bridge-cyclized alpha-melanocyte-stimulating hormone peptide
    Haixun Guo
    College of Pharmacy, University of New Mexico, Albuquerque, NM 87131, USA
    Nucl Med Biol 36:267-76. 2009

Collaborators

Detail Information

Publications32

  1. ncbi Peptide-targeted radionuclide therapy for melanoma
    Yubin Miao
    College of Pharmacy, University of New Mexico, 2502 Marble NE, MSC09 5360, Albuquerque, NM 87131, USA
    Crit Rev Oncol Hematol 67:213-28. 2008
    ..The lack of effective treatments for metastatic melanoma and end-stage disease underscores the necessity to develop and implement new treatment strategies, such as peptide-targeted radionuclide therapy...
  2. ncbi 203Pb-labeled alpha-melanocyte-stimulating hormone peptide as an imaging probe for melanoma detection
    Yubin Miao
    Department of Dermatology, University of New Mexico, Albuquerque, New Mexico 87131, USA
    J Nucl Med 49:823-9. 2008
    ..The purpose of this study was to evaluate the potential of (203)Pb-DOTA-Re(Arg(11))CCMSH as a matched-pair SPECT agent for (212)Pb-DOTA-Re(Arg(11))CCMSH...
  3. ncbi 111In-labeled lactam bridge-cyclized alpha-melanocyte stimulating hormone peptide analogues for melanoma imaging
    Yubin Miao
    College of Pharmacy, University of New Mexico, Albuquerque, New Mexico 87131, USA
    Bioconjug Chem 19:539-47. 2008
    ....
  4. ncbi Alpha-melanocyte stimulating hormone peptide-targeted melanoma imaging
    Yubin Miao
    College of Pharmacy, University of New Mexico, Albuquerque, NM 87131 0001, USA
    Front Biosci 12:4514-24. 2007
    ..This review highlights the strategies being used to design alpha-MSH peptide radiopharmaceuticals to target MC1 receptors and some recent developments of radiolabeled alpha-MSH peptide analogues for melanoma imaging...
  5. ncbi Reducing renal uptake of 90Y- and 177Lu-labeled alpha-melanocyte stimulating hormone peptide analogues
    Yubin Miao
    Department of Internal Medicine, University of Missouri Columbia, Columbia, MO 65211, USA
    Nucl Med Biol 33:723-33. 2006
    ....
  6. ncbi Evaluation of the human melanoma targeting properties of radiolabeled alpha-melanocyte stimulating hormone peptide analogues
    Yubin Miao
    Department of Biochemistry, University of Missouri-Columbia, Columbia, Missouri 65211, USA
    Bioconjug Chem 14:1177-84. 2003
    ..Moreover, the biodistribution properties of (188)Re-(Arg(11))CCMSH and (188)Re-CCMSH highlight their potential as therapeutic agents for human melanoma...
  7. ncbi Effect of DOTA position on melanoma targeting and pharmacokinetic properties of 111In-labeled lactam bridge-cyclized alpha-melanocyte stimulating hormone peptide
    Haixun Guo
    College of Pharmacy, Cancer Research Treatment Center, Department of Cell Biology and Physiology, Department of Pathology, Department of Dermatology, University of New Mexico, Albuquerque, New Mexico 87131, USA
    Bioconjug Chem 20:2162-8. 2009
    ....
  8. ncbi Reduction of the ring size of radiolabeled lactam bridge-cyclized alpha-MSH peptide, resulting in enhanced melanoma uptake
    Haixun Guo
    College of Pharmacy, University of New Mexico, Albuquerque, New Mexico 87131, USA
    J Nucl Med 51:418-26. 2010
    ..The purpose of this study was to examine the profound effect of the ring size of the radiolabeled lactam bridge-cyclized alpha-melanocyte-stimulating hormone (alpha-MSH) peptide on its melanoma-targeting properties...
  9. ncbi Therapeutic efficacy of a 188Re-labeled alpha-melanocyte-stimulating hormone peptide analog in murine and human melanoma-bearing mouse models
    Yubin Miao
    Department of Biochemistry, University of Missouri-Columbia, Columbia, MO 65211, USA
    J Nucl Med 46:121-9. 2005
    ..188)Re-(Arg(11))CCMSH appears to be a promising radiolabeled peptide for targeted radionuclide therapy of melanoma...
  10. ncbi Metastatic melanoma imaging with an (111)In-labeled lactam bridge-cyclized alpha-melanocyte-stimulating hormone peptide
    Haixun Guo
    College of Pharmacy, University of New Mexico, Albuquerque, NM 87131, USA
    Nucl Med Biol 36:267-76. 2009
    ....
  11. ncbi Replacement of the Lys linker with an Arg linker resulting in improved melanoma uptake and reduced renal uptake of Tc-99m-labeled Arg-Gly-Asp-conjugated alpha-melanocyte stimulating hormone hybrid peptide
    Jianquan Yang
    College of Pharmacy, University of New Mexico, Albuquerque, NM 87131, USA
    Bioorg Med Chem 18:6695-700. 2010
    ....
  12. ncbi Modification of the structure of a metallopeptide: synthesis and biological evaluation of (111)In-labeled DOTA-conjugated rhenium-cyclized alpha-MSH analogues
    Zhen Cheng
    Department of Chemistry, 125 Chemistry Building, University of Missouri-Columbia, Columbia, MO 65211, USA
    J Med Chem 45:3048-56. 2002
    ..13 +/- 1.47% ID/g for (111)In-10 at 4 h pi. Complex 6 showed high melanoma uptake and lower kidney uptake than the corresponding Lys(11) analogues, supporting 6 for further investigations as a potential therapeutic radiopharmaceutical...
  13. ncbi Therapeutic efficacy of a 177Lu-labeled DOTA conjugated alpha-melanocyte-stimulating hormone peptide in a murine melanoma-bearing mouse model
    Yubin Miao
    College of Pharmacy, University of New Mexico, Albuquerque, NM, USA
    Cancer Biother Radiopharm 22:333-41. 2007
    ..The aim of this study was to examine the therapeutic efficacy of (177)Lu-DOTA-Re(Arg(11))CCMSH in the B16/F1 murine melanoma-bearing mouse model...
  14. ncbi In vivo evaluation of 188Re-labeled alpha-melanocyte stimulating hormone peptide analogs for melanoma therapy
    Yubin Miao
    Department of Biochemistry, University of Missouri-Columbia, Columbia, MO 65211, USA
    Int J Cancer 101:480-7. 2002
    ..Improved tumor uptake and reduced kidney retention of 188Re-(Arg(11))CCMSH will facilitate targeted irradiation of melanoma tumors while minimizing the dose to the kidneys...
  15. ncbi Melanoma therapy via peptide-targeted {alpha}-radiation
    Yubin Miao
    Department of Biochemistry, University of Missouri-Columbia, Columbia, Missouri 65211, USA
    Clin Cancer Res 11:5616-21. 2005
    ..212)Pb-DOTA-Re(Arg(11))CCMSH seems to be a very promising radiopharmaceutical for targeted radionuclide therapy of melanoma...
  16. ncbi 99mTc- and 111In-labeled alpha-melanocyte-stimulating hormone peptides as imaging probes for primary and pulmonary metastatic melanoma detection
    Yubin Miao
    College of Pharmacy, University of New Mexico, Albuquerque, New Mexico, USA
    J Nucl Med 48:73-80. 2007
    ....
  17. ncbi Effects of the amino acid linkers on the melanoma-targeting and pharmacokinetic properties of 111In-labeled lactam bridge-cyclized alpha-MSH peptides
    Haixun Guo
    College of Pharmacy, University of New Mexico, Albuquerque, New Mexico 87131, USA
    J Nucl Med 52:608-16. 2011
    ....
  18. ncbi Evaluation of a novel Arg-Gly-Asp-conjugated α-melanocyte stimulating hormone hybrid peptide for potential melanoma therapy
    Jianquan Yang
    College of Pharmacy, University of New Mexico, Albuquerque, New Mexico 87131 0001, USA
    Bioconjug Chem 20:1634-42. 2009
    ..The purpose of this study was to determine whether Arg-Gly-Asp (RGD)-conjugated α-melanocyte stimulating hormone (α-MSH) hybrid peptide could be employed to target melanocortin-1 (MC1) receptor for potential melanoma therapy...
  19. ncbi Gallium-67-labeled lactam bridge-cyclized alpha-melanocyte stimulating hormone peptide for primary and metastatic melanoma imaging
    Haixun Guo
    College of Pharmacy, Cancer Research Treatment Center, and Department of Dermatology, University of New Mexico, Albuquerque, New Mexico 87131, USA
    Bioconjug Chem 20:2356-63. 2009
    ..67Ga-DOTA-GlyGlu-CycMSH exhibited favorable melanoma targeting and imaging properties, highlighting its potential as an effective imaging probe for early detection of primary and metastatic melanoma...
  20. ncbi Tumor-targeting properties of 90Y- and 177Lu-labeled alpha-melanocyte stimulating hormone peptide analogues in a murine melanoma model
    Yubin Miao
    Department of Internal Medicine, University of Missouri Columbia, 65211, USA
    Nucl Med Biol 32:485-93. 2005
    ..The purpose of this study was to compare the tumor-targeting properties of (90)Y-DOTA-Re(Arg(11))CCMSH and (177)Lu-DOTA-Re(Arg(11))CCMSH in a murine melanoma mouse model...
  21. ncbi Structural modification on the Lys linker enhanced tumor to kidney uptake ratios of 99mTc-labeled RGD-conjugated α-MSH hybrid peptides
    Jianquan Yang
    College of Pharmacy, University of New Mexico, Albuquerque, New Mexico 87131, United States
    Mol Pharm 9:1418-24. 2012
    ..A dramatically enhanced tumor-to-kidney uptake ratio of (99m)Tc-RGD-(Arg(11))CCMSH suggests that (188)Re-RGD-(Arg(11))CCMSH may behave in a similar fashion warranting future evaluation for melanoma treatment...
  22. ncbi Substitution of Gly with Ala enhanced the melanoma uptake of technetium-99m-labeled Arg-Ala-Asp-conjugated alpha-melanocyte stimulating hormone peptide
    Jianquan Yang
    College of Pharmacy, University of New Mexico, Albuquerque, NM 87131, USA
    Bioorg Med Chem Lett 22:1541-5. 2012
    ....
  23. ncbi A novel indium-111-labeled gonadotropin-releasing hormone peptide for human prostate cancer imaging
    Haixun Guo
    College of Pharmacy, University of New Mexico, Albuquerque, NM 87131, USA
    Bioorg Med Chem Lett 21:5184-7. 2011
    ..The successful imaging of DU145 human prostate cancer-xenografted tumor lesions using (111)In-DOTA-Ahx-(d-Lys(6)-GnRH1) highlighted its potential as a novel imaging probe for human prostate cancer imaging...
  24. ncbi Technetium-99m-labeled Arg-Gly-Asp-conjugated alpha-melanocyte stimulating hormone hybrid peptides for human melanoma imaging
    Jianquan Yang
    College of Pharmacy, University of New Mexico, Albuquerque, NM 87131, USA
    Nucl Med Biol 37:873-83. 2010
    ....
  25. ncbi Synthesis and evaluation of novel gonadotropin-releasing hormone receptor-targeting peptides
    Haixun Guo
    College of Pharmacy, University of New Mexico, Albuquerque, New Mexico 87131, United States
    Bioconjug Chem 22:1682-9. 2011
    ..The successful imaging of MDA-MB-231 human breast cancer-xenografted tumor lesions using (111)In-DOTA-Ahx-(D-Lys(6)-GnRH1) suggested its potential as a novel imaging probe for human breast cancer imaging...
  26. ncbi Alpha-melanocyte-stimulating hormone peptide analogs labeled with technetium-99m and indium-111 for malignant melanoma targeting
    Jianqing Chen
    Department of Biochemistry, University of Missouri, Columbia, Missouri, USA
    Cancer 94:1196-201. 2002
    ....
  27. ncbi Melanoma imaging with pretargeted bivalent bacteriophage
    Jessica R Newton
    Department of Biochemistry, University of Missouri, Columbia, Missouri, USA
    J Nucl Med 48:429-36. 2007
    ..This study provides proof of principle for the use of phage displaying multiple melanocortin-1 receptor-homing peptides for the pretargeting and subsequent imaging of murine melanomas in vivo...
  28. ncbi Design and Evaluation of New Tc-99m-Labeled Lactam Bridge-Cyclized Alpha-MSH Peptides for Melanoma Imaging
    Haixun Guo
    College of Pharmacy, Cancer Research and Treatment Center, Department of Dermatology, University of New Mexico, Albuquerque, New Mexico 87131, United States
    Mol Pharm 10:1400-8. 2013
    ..Overall, high melanoma uptake coupled with fast urinary clearance of (99m)Tc(EDDA)-HYNIC-GGNle-CycMSHhex highlighted its potential for metastatic melanoma detection in the future...
  29. ncbi Melanoma targeting property of a Lu-177-labeled lactam bridge-cyclized alpha-MSH peptide
    Haixun Guo
    College of Pharmacy, University of New Mexico, Albuquerque, NM 87131, USA
    Bioorg Med Chem Lett 23:2319-23. 2013
    ..Overall, high melanoma uptake coupled with fast urinary clearance of (177)Lu-DOTA-GGNle-CycMSHhex underscored its potential for melanoma treatment in the future...
  30. ncbi Gallium-68-labeled DOTA-rhenium-cyclized alpha-melanocyte-stimulating hormone analog for imaging of malignant melanoma
    Lihui Wei
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Nucl Med Biol 34:945-53. 2007
    ..This encouraged us to investigate DOTA-ReCCMSH(Arg11) labeled with another beta+-emitting radionuclide, 68Ga...
  31. ncbi Synthesis and biologic evaluation of 64Cu-labeled rhenium-cyclized alpha-MSH peptide analog using a cross-bridged cyclam chelator
    Lihui Wei
    Division of Radiological Sciences, Mallinckrodt Institute of Radiology and the Alvin J Siteman Cancer Center, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Nucl Med 48:64-72. 2007
    ..The goal of this study was to conjugate CBTE2A to the alpha-MSH targeting ReCCMSH(Arg(11)) peptide for labeling to (64)Cu and to investigate whether the increased metal-chelate stability with CBTE2A would improve imaging quality...
  32. ncbi Imaging of melanoma using 64Cu- and 86Y-DOTA-ReCCMSH(Arg11), a cyclized peptide analogue of alpha-MSH
    Paul McQuade
    Division of Radiological Sciences, Mallinckrodt Institute of Radiology and the Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri 63110, USA
    J Med Chem 48:2985-92. 2005
    ..The data obtained suggests that DOTA-ReCCMSH(Arg(11)), when labeled with beta(+)-emitting radionuclides, has the potential for early detection of malignant melanoma by exploiting the sensitivity and high resolution of PET...