Research Topics
| Hongyu MiaoSummaryAffiliation: University of Rochester Country: USA Publications
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Detail Information
Publications
Evaluation of multitype mathematical models for CFSE-labeling experiment dataHongyu Miao
Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 630, Rochester, NY 14642, USA
Bull Math Biol 74:300-26. 2012..This model was then employed to understand the proliferation pattern of CD4+ and CD8+ T cells under polyclonal stimulation...
Quantifying the early immune response and adaptive immune response kinetics in mice infected with influenza A virusHongyu Miao
Department of Biostatistics and Computational Biology, University of Rochester, Rochester, New York 146421, USA
J Virol 84:6687-98. 2010..Also, simulation studies were performed to understand the relative contributions of biological parameters to IAV clearance. This study provides a basis to better understand and predict influenza virus immunity...
Modeling of influenza-specific CD8+ T cells during the primary response indicates that the spleen is a major source of effectorsHulin Wu
Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY 14642, USA
J Immunol 187:4474-82. 2011..Together, these efforts provide a better understanding of the primary CD8(+) T cell response to influenza infection, changing the view that the spleen plays a minor role in the primary immune response...
Ki-67 expression reveals strong, transient influenza specific CD4 T cell responses after adult vaccinationXi Li
David H Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
Vaccine 30:4581-4. 2012....
Modeling and estimation of kinetic parameters and replicative fitness of HIV-1 from flow-cytometry-based growth competition experimentsHongyu Miao
Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 630, Rochester, NY, 14642, USA
Bull Math Biol 70:1749-71. 2008..Practical identifiability was investigated via Monte Carlo simulations...
Differential equation modeling of HIV viral fitness experiments: model identification, model selection, and multimodel inferenceHongyu Miao
Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 630, Rochester, New York 14642, USA
Biometrics 65:292-300. 2009..We expect that the proposed modeling and inference approaches for the DE models can be widely used for a variety of biomedical studies...
Simulation and prediction of the adaptive immune response to influenza A virus infectionHa Youn Lee
Department of Biostatistics and Computational Biology, University of Rochester, Rochester, New York 14642, USA
J Virol 83:7151-65. 2009..We further compared alternative model structures, for example, B-cell activation directly by the virus versus that through professional antigen-presenting cells or dendritic cell licensing of CD8 T cells...
Parameter identifiability and estimation of HIV/AIDS dynamic modelsHulin Wu
Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 630, Rochester, NY 14642, USA
Bull Math Biol 70:785-99. 2008..Although we have developed the identifiability methods based on an HIV dynamic model, the proposed methodologies are generally applicable to any ordinary differential equation systems...
Ultrasonic excitation of a bubble inside a deformable tube: implications for ultrasonically induced hemorrhageHongyu Miao
Mechanical Engineering, University of Rochester, Rochester, New York 14627, USA
J Acoust Soc Am 124:2374-84. 2008..2-1.0 MPa) on bubble response and tube dilation were investigated. As the tube thickness, tube radius, and acoustic frequency decreased, the maximum hoop stress increased, indicating a higher potential for tube rupture and hemorrhage...
