Joshua D Mezrich

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. pmc SU5416, a VEGF receptor inhibitor and ligand of the AHR, represents a new alternative for immunomodulation
    Joshua D Mezrich
    Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America
    PLoS ONE 7:e44547. 2012
  2. pmc Differential outcomes of expanded-criteria donor renal allografts according to recipient age
    Joshua D Mezrich
    Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 7375, USA
    Clin J Am Soc Nephrol 7:1163-71. 2012
  3. pmc An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells
    Joshua D Mezrich
    Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 7375, USA
    J Immunol 185:3190-8. 2010
  4. pmc Increased C4d in post-reperfusion biopsies and increased donor specific antibodies at one-week post transplant are risk factors for acute rejection in mild to moderately sensitized kidney transplant recipients
    Arjang Djamali
    Department of Surgery, University of Wisconsin, Madison, Wisconsin 51703, USA
    Kidney Int 83:1185-92. 2013
  5. pmc Complications associated with liver transplantation in the obese recipient
    John C LaMattina
    Division of Transplantation, University of Maryland School of Medicine, Baltimore, MD, USA
    Clin Transplant 26:910-8. 2012
  6. pmc Native kidney function following liver transplantation using calcineurin inhibitors: single-center analysis with 20 years of follow-up
    John C LaMattina
    Division of Transplantation, University of Maryland School of Medicine, Baltimore, MD, USA
    Clin Transplant 27:193-202. 2013
  7. pmc Chronic kidney disease stage progression in liver transplant recipients
    John C LaMattina
    Department of Medicine, University of Wisconsin, H4 564 CSC, 600 Highland Avenue, Madison, WI 53792, USA
    Clin J Am Soc Nephrol 6:1851-7. 2011
  8. pmc Simultaneous pancreas and kidney (SPK) retransplantation in prior SPK recipients
    John C LaMattina
    Division of Transplantation, University of Maryland School of Medicine, Baltimore, MD, USA
    Clin Transplant 26:495-501. 2012
  9. pmc Donation after cardiac death: a 29-year experience
    Janet M Bellingham
    Division of Organ Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 7375, USA
    Surgery 150:692-702. 2011
  10. pmc Alemtuzumab as compared to alternative contemporary induction regimens
    John C LaMattina
    Division of Transplantation, University of Maryland School of Medicine, Baltimore, MD 53792, USA
    Transpl Int 25:518-26. 2012

Collaborators

Detail Information

Publications17

  1. pmc SU5416, a VEGF receptor inhibitor and ligand of the AHR, represents a new alternative for immunomodulation
    Joshua D Mezrich
    Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America
    PLoS ONE 7:e44547. 2012
    ....
  2. pmc Differential outcomes of expanded-criteria donor renal allografts according to recipient age
    Joshua D Mezrich
    Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 7375, USA
    Clin J Am Soc Nephrol 7:1163-71. 2012
    ..This study sought to determine whether older recipients had significantly worse outcomes from receiving ECD kidneys and whether outcomes of ECD versus standard-criteria donor (SCD) kidneys differed in younger recipients...
  3. pmc An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells
    Joshua D Mezrich
    Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 7375, USA
    J Immunol 185:3190-8. 2010
    ..These results shed light on the relationship of IDO to the generation of Tregs, in addition to highlighting the central importance of the AHR in T cell differentiation. All tissues and cells were derived from mice...
  4. pmc Increased C4d in post-reperfusion biopsies and increased donor specific antibodies at one-week post transplant are risk factors for acute rejection in mild to moderately sensitized kidney transplant recipients
    Arjang Djamali
    Department of Surgery, University of Wisconsin, Madison, Wisconsin 51703, USA
    Kidney Int 83:1185-92. 2013
    ..8-fold risk of rejection. Thus, C4d staining in post-reperfusion biopsies and an early rise in donor specific antibodies after transplantation are risk factors for rejection in moderately sensitized patients...
  5. pmc Complications associated with liver transplantation in the obese recipient
    John C LaMattina
    Division of Transplantation, University of Maryland School of Medicine, Baltimore, MD, USA
    Clin Transplant 26:910-8. 2012
    ....
  6. pmc Native kidney function following liver transplantation using calcineurin inhibitors: single-center analysis with 20 years of follow-up
    John C LaMattina
    Division of Transplantation, University of Maryland School of Medicine, Baltimore, MD, USA
    Clin Transplant 27:193-202. 2013
    ..As outcomes from liver transplantation continue to improve, long-term native kidney function in these recipients becomes more critical to patient survival...
  7. pmc Chronic kidney disease stage progression in liver transplant recipients
    John C LaMattina
    Department of Medicine, University of Wisconsin, H4 564 CSC, 600 Highland Avenue, Madison, WI 53792, USA
    Clin J Am Soc Nephrol 6:1851-7. 2011
    ..There is little information on chronic kidney disease (CKD) stage progression rates and outcomes in liver transplant recipients. Identifying modifiable risk factors may help prevent CKD progression in liver transplant recipients...
  8. pmc Simultaneous pancreas and kidney (SPK) retransplantation in prior SPK recipients
    John C LaMattina
    Division of Transplantation, University of Maryland School of Medicine, Baltimore, MD, USA
    Clin Transplant 26:495-501. 2012
    ..On the basis of these experiences, we began performing repeat SPK in prior SPK recipients (n = 9)...
  9. pmc Donation after cardiac death: a 29-year experience
    Janet M Bellingham
    Division of Organ Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 7375, USA
    Surgery 150:692-702. 2011
    ..To report the long-term outcomes of 1218 organs transplanted from donation after cardiac death (DCD) donors from January 1980 through December 2008...
  10. pmc Alemtuzumab as compared to alternative contemporary induction regimens
    John C LaMattina
    Division of Transplantation, University of Maryland School of Medicine, Baltimore, MD 53792, USA
    Transpl Int 25:518-26. 2012
    ..3, P = 0.01), CMV infections (HR 1.6, P = 0.001), and AMR (HR 1.5, P = 0.002). The significantly worse graft survival in the alemtuzumab cohort may be due to the increased rates of AMR and infectious complications...
  11. doi request reprint Antithymocyte globulin is associated with a lower incidence of de novo donor-specific antibodies in moderately sensitized renal transplant recipients
    Marissa M Brokhof
    1 Department of Pharmacy, University of Wisconsin, Madison, WI 2 Department of Surgery, University of Wisconsin, Madison, WI 3 Department of Medicine, University of Wisconsin, Madison, WI 4 Departments of Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI 5 Address correspondence to Arjang Djamali, M D, M S, F A S N, 5142 MFCB 1685 Highland Avenue, Madison, WI 53705
    Transplantation 97:612-7. 2014
    ..Recent evidence suggests that de novo donor-specific antibodies (dnDSA) are associated with antibody-mediated rejection (ABMR) and graft failure after kidney transplantation. The effects of induction immunosuppression on dnDSA are unknown...
  12. pmc Pretransplant immune regulation predicts allograft outcome: bidirectional regulation correlates with excellent renal transplant function in living-related donor-recipient pairs
    Ewa Jankowska-Gan
    Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Transplantation 93:283-90. 2012
    ..This paradox prompted us to revisit the "two-way" hypothesis of transplant tolerance--that the immune status of both the organ recipient and the organ donor critically influences allograft outcome...
  13. pmc Simultaneous liver and kidney transplantation using donation after cardiac death donors: a brief report
    John C LaMattina
    Division of Transplantation, University of Wisconsin, Madison, WI, USA
    Liver Transpl 17:591-5. 2011
    ..Although long-term outcomes remain unknown, the utilization of DCD organs for SLK transplantation should be considered a valid approach to safely expanding the donor organ pool...
  14. pmc The aryl hydrocarbon receptor: a novel target for immunomodulation in organ transplantation
    Michael Van Voorhis
    Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Transplantation 95:983-90. 2013
    ....
  15. pmc Exposure to atmospheric particulate matter enhances Th17 polarization through the aryl hydrocarbon receptor
    Michael Van Voorhis
    Department of Surgery, Division of Transplantation Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America
    PLoS ONE 8:e82545. 2013
    ....
  16. pmc The aryl hydrocarbon receptor: a perspective on potential roles in the immune system
    Emily A Stevens
    University of Wisconsin School of Medicine and Public Health, Madison, WI 53706 1599, USA
    Immunology 127:299-311. 2009
    ..We also will discuss the complexities of AHR pharmacology and genetics that may influence future studies of AHR in the immune system...
  17. ncbi request reprint Alemtuzumab induction and recurrence of glomerular disease after kidney transplantation
    Julio Pascual
    Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI 53713, USA
    Transplantation 83:1429-34. 2007
    ..An increase in the incidence of autoimmune diseases has been described in patients receiving alemtuzumab...