Nuala J Meyer

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi SNP-set analysis replicates acute lung injury genetic risk factors
    Nuala J Meyer
    Department of Medicine Pulmonary, Allergy, and Critical Care Division, Perelman School of Medicine University of Pennsylvania, 3600 Spruce Street, 874 Maloney, Philadelphia, PA 19104, USA
    BMC Med Genet 13:52. 2012
  2. ncbi Novel variants in the PRDX6 Gene and the risk of Acute Lung Injury following major trauma
    Melanie Rushefski
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, 3600 Spruce Street, Philadelphia, USA
    BMC Med Genet 12:77. 2011
  3. ncbi ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio
    Nuala J Meyer
    Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Am J Respir Crit Care Med 183:1344-53. 2011
  4. ncbi Variation in PTX3 is associated with primary graft dysfunction after lung transplantation
    Joshua M Diamond
    Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania School of Medicine, 3400 Spruce St, 8 West Gates, Philadelphia, PA 19104, USA
    Am J Respir Crit Care Med 186:546-52. 2012
  5. ncbi The association of early transfusion with acute lung injury in patients with severe injury
    Daniel N Holena
    Division of Traumatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Trauma Acute Care Surg 73:825-31. 2012
  6. ncbi IL1RN Coding Variant Is Associated with Lower Risk of Acute Respiratory Distress Syndrome and Increased Plasma IL-1 Receptor Antagonist
    Nuala J Meyer
    1 Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, and
    Am J Respir Crit Care Med 187:950-9. 2013
  7. ncbi African American race, obesity, and blood product transfusion are risk factors for acute kidney injury in critically ill trauma patients
    Michael G S Shashaty
    Division of Pulmonary, Allergy, and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Crit Care 27:496-504. 2012
  8. ncbi Elevated plasma angiopoietin-2 levels and primary graft dysfunction after lung transplantation
    Joshua M Diamond
    Pulmonary, Allergy, and Critical Care Division, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
    PLoS ONE 7:e51932. 2012
  9. ncbi Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma
    Jason D Christie
    Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 7:e28268. 2012
  10. ncbi Lower serum endocan levels are associated with the development of acute lung injury after major trauma
    Mark E Mikkelsen
    Pulmonary, Allergy, and Critical Care Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Crit Care 27:522.e11-7. 2012

Collaborators

Detail Information

Publications10

  1. ncbi SNP-set analysis replicates acute lung injury genetic risk factors
    Nuala J Meyer
    Department of Medicine Pulmonary, Allergy, and Critical Care Division, Perelman School of Medicine University of Pennsylvania, 3600 Spruce Street, 874 Maloney, Philadelphia, PA 19104, USA
    BMC Med Genet 13:52. 2012
    ..We used a gene - based replication strategy to test the reproducibility of prior acute lung injury (ALI) candidate gene associations...
  2. ncbi Novel variants in the PRDX6 Gene and the risk of Acute Lung Injury following major trauma
    Melanie Rushefski
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, 3600 Spruce Street, Philadelphia, USA
    BMC Med Genet 12:77. 2011
    ..Little is known about genetic variation within the PRDX6 gene and its association with acute lung injury (ALI). In this study we sequenced the PRDX6 gene to uncover common variants, and tested association with ALI following major trauma...
  3. ncbi ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio
    Nuala J Meyer
    Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Am J Respir Crit Care Med 183:1344-53. 2011
    ..Acute lung injury (ALI) acts as a complex genetic trait, yet its genetic risk factors remain incompletely understood. Large-scale genotyping has not previously been reported for ALI...
  4. ncbi Variation in PTX3 is associated with primary graft dysfunction after lung transplantation
    Joshua M Diamond
    Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania School of Medicine, 3400 Spruce St, 8 West Gates, Philadelphia, PA 19104, USA
    Am J Respir Crit Care Med 186:546-52. 2012
    ..Elevated long pentraxin-3 (PTX3) levels are associated with the development of primary graft dysfunction (PGD) after lung transplantation. Abnormalities in innate immunity, mediated by PTX3 release, may play a role in PGD pathogenesis...
  5. ncbi The association of early transfusion with acute lung injury in patients with severe injury
    Daniel N Holena
    Division of Traumatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Trauma Acute Care Surg 73:825-31. 2012
    ..We hypothesized that the relationship between PRBC delivery and ALI risk varies through time after injury...
  6. ncbi IL1RN Coding Variant Is Associated with Lower Risk of Acute Respiratory Distress Syndrome and Increased Plasma IL-1 Receptor Antagonist
    Nuala J Meyer
    1 Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, and
    Am J Respir Crit Care Med 187:950-9. 2013
    ..Conclusions: The IL1RN SNP rs315952C is associated with decreased risk of ARDS in three populations with heterogeneous ARDS risk factors, and with increased plasma IL1RA response. IL1RA may attenuate ARDS risk...
  7. ncbi African American race, obesity, and blood product transfusion are risk factors for acute kidney injury in critically ill trauma patients
    Michael G S Shashaty
    Division of Pulmonary, Allergy, and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Crit Care 27:496-504. 2012
    ..Acute kidney injury (AKI) is a common source of morbidity after trauma. We sought to determine novel risk factors for AKI, by Acute Kidney Injury Network (AKIN) criteria, in critically ill trauma patients...
  8. ncbi Elevated plasma angiopoietin-2 levels and primary graft dysfunction after lung transplantation
    Joshua M Diamond
    Pulmonary, Allergy, and Critical Care Division, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
    PLoS ONE 7:e51932. 2012
    ..Angiopoietin-2 serves as a partial antagonist to the Tie-2 receptor and induces increased endothelial permeability. We hypothesized that elevated Ang2 levels would be associated with development of PGD...
  9. ncbi Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma
    Jason D Christie
    Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 7:e28268. 2012
    ..This study supports the feasibility of future multi-center GWA investigations of ALI risk, and identifies PPFIA1 as a potential functional candidate ALI risk gene for future research...
  10. ncbi Lower serum endocan levels are associated with the development of acute lung injury after major trauma
    Mark E Mikkelsen
    Pulmonary, Allergy, and Critical Care Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Crit Care 27:522.e11-7. 2012
    ..We tested the association of serum endocan levels with subsequent development of ALI after major trauma...