K C Meyer

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. pmc Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients
    Dieter Worlitzsch
    Institute of General and Environmental Hygiene, University of Tubingen, Tubingen, Germany
    J Clin Invest 109:317-25. 2002
  2. ncbi request reprint Immunosuppressive agents and interstitial lung disease: what are the risks?
    Keith C Meyer
    University of Wisconsin School of Medicine and Public Health, 610 Walnut St, Madison, WI 53726, USA
    Expert Rev Respir Med 8:263-6. 2014
  3. pmc Lung transplantation
    Keith C Meyer
    UW Lung Transplant and Advanced Pulmonary Disease Program, Section of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health 600 Highland Ave, Madison, WI 53792 USA
    F1000Prime Rep 5:16. 2013
  4. doi request reprint Immunosuppressive therapy for autoimmune lung diseases
    Keith C Meyer
    UW Lung Transplant and Advanced Pulmonary Disease Program, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Immunol Allergy Clin North Am 32:633-69. 2012
  5. pmc Neutrophil necrosis and annexin 1 degradation associated with airway inflammation in lung transplant recipients with cystic fibrosis
    Francis H C Tsao
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Medical School, University of Wisconsin, Clinical Science Center, Madison, 53792 9988, USA
    BMC Pulm Med 12:44. 2012
  6. doi request reprint Management of interstitial lung disease in elderly patients
    Keith C Meyer
    Section of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792 9988, USA
    Curr Opin Pulm Med 18:483-92. 2012
  7. ncbi request reprint Vascular endothelial growth factor in human lung transplantation
    K C Meyer
    Department of Medicine, University of Wisconsin Medical School, Madison, WI, USA
    Chest 119:137-43. 2001
  8. ncbi request reprint The role of bronchoalveolar lavage in interstitial lung disease
    Keith C Meyer
    Department of Medicine, University of Wisconsin Medical School, K4 930 Clinical Sciences Center, 600 Highland Avenue, Madison, WI 53792 9988, USA
    Clin Chest Med 25:637-49, v. 2004
  9. ncbi request reprint Bronchoalveolar lavage as a diagnostic tool
    Keith C Meyer
    Department of Medicine, Section of Allergy, Pulmonary, and Critical Care Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792 9988, USA
    Semin Respir Crit Care Med 28:546-60. 2007
  10. ncbi request reprint Lung infections and aging
    Keith C Meyer
    Department of Medicine, K4 930 Clinical Sciences Center, University of Wisconsin Medical School, 600 Highland Avenue, Madison, WI 53792 9988, USA
    Ageing Res Rev 3:55-67. 2004

Collaborators

Detail Information

Publications40

  1. pmc Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients
    Dieter Worlitzsch
    Institute of General and Environmental Hygiene, University of Tubingen, Tubingen, Germany
    J Clin Invest 109:317-25. 2002
    ..These studies indicate that novel therapies for CF include removal of hypoxic mucus plaques and antibiotics effective against P. aeruginosa adapted to anaerobic environments...
  2. ncbi request reprint Immunosuppressive agents and interstitial lung disease: what are the risks?
    Keith C Meyer
    University of Wisconsin School of Medicine and Public Health, 610 Walnut St, Madison, WI 53726, USA
    Expert Rev Respir Med 8:263-6. 2014
    ....
  3. pmc Lung transplantation
    Keith C Meyer
    UW Lung Transplant and Advanced Pulmonary Disease Program, Section of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health 600 Highland Ave, Madison, WI 53792 USA
    F1000Prime Rep 5:16. 2013
    ..This manuscript discusses recent and evolving advances in the field of lung transplantation...
  4. doi request reprint Immunosuppressive therapy for autoimmune lung diseases
    Keith C Meyer
    UW Lung Transplant and Advanced Pulmonary Disease Program, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Immunol Allergy Clin North Am 32:633-69. 2012
    ..Knowledge of their potential toxicities and interactions with other drugs combined with the adoption of a systematic approach to monitoring therapy can minimize life-threatening reactions...
  5. pmc Neutrophil necrosis and annexin 1 degradation associated with airway inflammation in lung transplant recipients with cystic fibrosis
    Francis H C Tsao
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Medical School, University of Wisconsin, Clinical Science Center, Madison, 53792 9988, USA
    BMC Pulm Med 12:44. 2012
    ..This study examined the viability of neutrophils retrieved from the proximal airways of lung transplant recipients with bacterial tracheobronchitis...
  6. doi request reprint Management of interstitial lung disease in elderly patients
    Keith C Meyer
    Section of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792 9988, USA
    Curr Opin Pulm Med 18:483-92. 2012
    ..This review seeks to inform readers of evolving concepts of ageing-associated risks for developing interstitial lung disease (ILD) and current approaches to the diagnosis and management of ILD in elderly patients...
  7. ncbi request reprint Vascular endothelial growth factor in human lung transplantation
    K C Meyer
    Department of Medicine, University of Wisconsin Medical School, Madison, WI, USA
    Chest 119:137-43. 2001
    ..To determine levels of the vascular endothelial growth factor (VEGF) isoform consisting of 165 amino acids (VEGF(165)) in BAL fluid (BALF) from lung transplant recipients (LTXs)...
  8. ncbi request reprint The role of bronchoalveolar lavage in interstitial lung disease
    Keith C Meyer
    Department of Medicine, University of Wisconsin Medical School, K4 930 Clinical Sciences Center, 600 Highland Avenue, Madison, WI 53792 9988, USA
    Clin Chest Med 25:637-49, v. 2004
    ..This discussion examines the usefulness of BAL in the diagnosis of specific forms of ILD...
  9. ncbi request reprint Bronchoalveolar lavage as a diagnostic tool
    Keith C Meyer
    Department of Medicine, Section of Allergy, Pulmonary, and Critical Care Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792 9988, USA
    Semin Respir Crit Care Med 28:546-60. 2007
    ..Examination of BAL cells or acellular components of BAL via gene microarray technology or proteomic analyses may allow BAL to assume a more prominent role in diagnosis and management of lung disease in the near future...
  10. ncbi request reprint Lung infections and aging
    Keith C Meyer
    Department of Medicine, K4 930 Clinical Sciences Center, University of Wisconsin Medical School, 600 Highland Avenue, Madison, WI 53792 9988, USA
    Ageing Res Rev 3:55-67. 2004
    ..This article will discuss various factors associated with advanced age that predispose the elderly to respiratory infections and summarize current approaches to treatment and prevention...
  11. doi request reprint Toxicity and monitoring of immunosuppressive therapy used in systemic autoimmune diseases
    Keith C Meyer
    Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Clin Chest Med 31:565-88. 2010
    ..Appropriate monitoring may prevent or limit toxicity from these agents, and knowledge of drug-drug interactions is essential when these agents are prescribed...
  12. doi request reprint The role of immunity and inflammation in lung senescence and susceptibility to infection in the elderly
    Keith C Meyer
    Department of Medicine, Section of Allergy, Pulmonary, and Critical Care Medicine, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, Madison, WI 53792, USA
    Semin Respir Crit Care Med 31:561-74. 2010
    ..It will discuss risk factors, identify pathogens that typically lead to respiratory infections in the elderly, and review current approaches to treatment and prevention of respiratory infections in the elderly population...
  13. ncbi request reprint Interstitial lung disease in the elderly: pathogenesis, diagnosis and management
    K C Meyer
    Section of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, USA
    Sarcoidosis Vasc Diffuse Lung Dis 28:3-17. 2011
    ..An effective treatment for IPF remains elusive, but many patients will benefit from supportive care and treatment of various co-morbid conditions that are often found in patients with IPF...
  14. ncbi request reprint Inflammation and surfactant
    Keith C Meyer
    Department of Medicine, K4 930 Clinical Sciences Center, 600 Highland Avenue, Madison, WI 53792 9988, USA
    Paediatr Respir Rev 3:308-14. 2002
    ..Although surfactant replacement therapy is indicated for infant respiratory distress syndrome, there is no well-proven role for exogenous surfactant in the treatment of inflammatory lung disorders at the present time...
  15. ncbi request reprint Neutrophils and low-grade inflammation in the seemingly normal aging human lung
    K C Meyer
    Department of Medicine, H6 380 Clinical Sciences Center, Madison, WI 53792, USA
    Mech Ageing Dev 104:169-81. 1998
    ..7+/-1.9 micromol/ml, P < 0.01) were also significantly increased in the oldest age group. This cross-sectional investigation suggests that low-grade inflammation exists in the air spaces of many clinically normal, older individuals...
  16. ncbi request reprint Function and composition of pulmonary surfactant and surfactant-derived fatty acid profiles are altered in young adults with cystic fibrosis
    K C Meyer
    Department of Medicine, Section of Pulmonary and Critical Care Medicine, University of Wisconsin Medical School, Madison, WI, USA
    Chest 118:164-74. 2000
    ..To determine whether chronic lung inflammation in young adult patients with cystic fibrosis (CF) alters the composition and function of surfactant and surfactant components in bronchoalveolar secretions...
  17. ncbi request reprint The role of immunity in susceptibility to respiratory infection in the aging lung
    K C Meyer
    Department of Medicine, Section of Pulmonary and Critical Care Medicine, University of Wisconsin Medical School, K4 930 Clinical Sciences Center, 600 Highland Avenue, Madison, WI 53792 3240, USA
    Respir Physiol 128:23-31. 2001
    ..However, better stimulation of specific immune responses with improved vaccines and more widespread use of these vaccines for protection of elderly individuals are needed...
  18. ncbi request reprint Neutrophils, unopposed neutrophil elastase, and alpha1-antiprotease defenses following human lung transplantation
    K C Meyer
    Sections of Pulmonary and Critical Care Medicine and Cardiothoracic Surgery, University of Wisconsin Hospital and Clinics, Madison, Wisconsin 53792, USA
    Am J Respir Crit Care Med 164:97-102. 2001
    ..Our findings indicate that unopposed NE activity can be found in both alpha1-AP-deficient and alpha1-AP-sufficient recipients after transplantation, usually in association with endobronchial bacterial infection...
  19. ncbi request reprint Aging
    Keith C Meyer
    Department of Medicine, University of Wisconsin Medical School, K4 930 Clinical Sciences Center, 600 Highland Avenue, Madison, WI 53792 9988, USA
    Proc Am Thorac Soc 2:433-9. 2005
    ....
  20. ncbi request reprint Degradation of annexin I in bronchoalveolar lavage fluid from patients with cystic fibrosis
    F H Tsao
    Department of Pediatrics, Clinical Science Center, University of Wisconsin, Madison 53715, USA
    Am J Respir Cell Mol Biol 18:120-8. 1998
    ..0 to 8.5-9.0) and greatly diminished annexin I functional activity. Our findings demonstrate that annexin I degradation in epithelial lining fluid is closely related to lung inflammation...
  21. ncbi request reprint Soluble donor HLA class I and beta 2m-free heavy chain in serum of lung transplant recipients: steady-state levels and increases in patients with recurrent CMV infection, acute rejection episodes, and poor outcome
    L D DeVito-Haynes
    Department of Surgery, University of Wisconsin, Madison, Wisconsin 53792, USA
    Hum Immunol 61:1370-82. 2000
    ..However, recall responses to CMV and controlled immune responses to donor may result in little or no activation of sHLA class I release...
  22. doi request reprint Assessment of current practice in the diagnosis and therapy of idiopathic pulmonary fibrosis
    T Peikert
    Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Mayo Building East 18, Rochester, MN, USA
    Respir Med 102:1342-8. 2008
    ..Acceptance and implementation of these guidelines have not been assessed. We surveyed the fellows of the American College of Chest Physicians (FCCP) to establish current practice patterns regarding the diagnosis and therapy of IPF...
  23. ncbi request reprint Assessment of nitric oxide formation during exercise
    C M St Croix
    Department of Preventive Medicine, University of Wisconsin Madison, Madison, Wisconsin, USA
    Am J Respir Crit Care Med 159:1125-33. 1999
    ....
  24. ncbi request reprint Quantitative and qualitative analysis of rhinovirus infection in bronchial tissues
    Anne G Mosser
    University of Wisconsin, K4 928 CSC 9988, 600 Highland Avenue, Madison, WI 53792, USA
    Am J Respir Crit Care Med 171:645-51. 2005
    ..These results confirm that infection of lower airway tissues is a frequent finding during a cold and further demonstrate a patchy distribution of infected cells, a pattern similar to that reported in upper airway tissues...
  25. doi request reprint Lung transplantation with donation after cardiac death donors: long-term follow-up in a single center
    Nilto C De Oliveira
    Department of Surgery, Division of Cardiothoracic Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wis, USA
    J Thorac Cardiovasc Surg 139:1306-15. 2010
    ..We sought to examine long-term outcomes at the University of Wisconsin for all lung transplant recipients who received lungs from donation after cardiac death donors since the initiation of this program in 1993...
  26. ncbi request reprint A continuous fluorescence assay for the determination of calcium-dependent secretory phospholipase A2 activity in serum
    Francis H C Tsao
    Department of Medicine, Section of Pulmonary and Critical Care Medicine, University of Wisconsin Medical School, Madison, WI 53792, USA
    Clin Chim Acta 379:119-26. 2007
    ..We describe a quick, sensitive and reliable microplate continuous fluorescence assay for determining sPLA(2) activity in serum...
  27. pmc IL-17-dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants
    William J Burlingham
    Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
    J Clin Invest 117:3498-506. 2007
    ..These data suggest that while alloimmunity initiates lung transplant rejection, de novo autoimmunity mediated by col(V)-specific Th17 cells and monocyte/macrophage accessory cells ultimately causes progressive airway obliteration...
  28. ncbi request reprint Lung transplantation for cystic fibrosis: current concepts and one center's experience
    J E Spahr
    University of Wisconsin School of Medicine and Public Health, WI, USA
    J Cyst Fibros 6:334-50. 2007
    ....
  29. doi request reprint Bronchoalveolar lavage for the evaluation of interstitial lung disease: is it clinically useful?
    K C Meyer
    Division of Pulmonary and Critical Care Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Eur Respir J 38:761-9. 2011
    ..This perspective reviews the current status of using BAL as a diagnostic tool for the diagnosis of ILD...
  30. doi request reprint Non-acidic supraesophageal reflux associated with diffuse alveolar damage and allograft dysfunction after lung transplantation: a case report
    Kevin D Halsey
    Department of Medicine, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin 53705, USA
    J Heart Lung Transplant 27:564-7. 2008
    ..We report a case of diffuse alveolar damage-associated allograft dysfunction in a patient found to have significant non-acid gastroesophageal reflux...
  31. doi request reprint Redo lung transplantation for acute and chronic lung allograft failure: long-term follow-up in a single center
    Satoru Osaki
    Division of Cardiothoracic Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, University of Wisconsin Hospital and Clinics, Madison, WI 53792 3236, USA
    Eur J Cardiothorac Surg 34:1191-7. 2008
    ..This study was undertaken to evaluate outcomes of redo lung transplantation (LT) for acute and chronic graft failure...
  32. doi request reprint Therapies for interstitial lung disease: past, present and future
    Robert Kim
    Department of Medicine, University of Wisconsin School of Medicine and Public Health, WI, USA
    Ther Adv Respir Dis 2:319-38. 2008
    ..Lung transplantation remains an option for advanced lung disease that is progressive and unresponsive to non-surgical therapies...
  33. ncbi request reprint Role of sensory input from the lungs in control of muscle sympathetic nerve activity during and after apnea in humans
    Rami N Khayat
    Department of Medicine, University of Wisconsin Madison, Madison, WI 53706, USA
    J Appl Physiol 97:635-40. 2004
    ..In contrast, vagal afferent input elicited by hyperventilation-induced lung stretch plays an important role in the profound, rapid sympathetic inhibition that occurs after resumption of breathing after apnea...
  34. doi request reprint Pulmonary hypertension in interstitial lung disease
    David Polomis
    Department of Medicine, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin 53792 9988, USA
    Curr Opin Pulm Med 14:462-9. 2008
    ..To examine recent advances in the understanding of the prevalence, pathophysiology, natural history, diagnosis, and treatment of pulmonary hypertension associated with interstitial lung disease...
  35. ncbi request reprint Aspergillus infection in lung transplant recipients with cystic fibrosis: risk factors and outcomes comparison to other types of transplant recipients
    Mohamed Helmi
    Department of Medicine, Section of Pulmonary and Critical Care Medicine, University of Wisconsin, Madison, USA
    Chest 123:800-8. 2003
    ..To characterize Aspergillus infections in lung transplant recipients with cystic fibrosis (CF)...
  36. ncbi request reprint Drug treatment of pneumococcal pneumonia in the elderly
    Sridhar Neralla
    Section of Pulmonary and Critical Care Medicine, University of Wisconsin Hospital and Clinics, Madison, Wisconsin 53792 9988, USA
    Drugs Aging 21:851-64. 2004
    ....
  37. ncbi request reprint Pre-transplant mechanical ventilation and outcome in patients with cystic fibrosis
    Raquel R Bartz
    Department of Medicine, University of Wisconsin, Madison, Wisconsin 53792 9988, USA
    J Heart Lung Transplant 22:433-8. 2003
    ....
  38. doi request reprint The impact of the lung allocation scoring system at the single national Veterans Affairs Hospital lung transplantation program
    Satoru Osaki
    Division of Cardiothoracic Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
    Eur J Cardiothorac Surg 36:497-501. 2009
    ..This study was undertaken to evaluate the impact of the LAS on a unique patient population undergoing lung transplantation (LTX) at the single national Veterans Affairs (VA) LT center...
  39. ncbi request reprint Role of lung inflammatory mediators as a cause of exercise-induced arterial hypoxemia in young athletes
    Thomas J Wetter
    John Rankin Laboratory of Pulmonary Medicine, Department of Preventive Medicine, Clinical Sciences Center, University of Wisconsin, Madison 53705, USA
    J Appl Physiol (1985) 93:116-26. 2002
    ..We conclude that airway inflammation is of insufficient magnitude to cause impairments in gas exchange and does not appear to be linked to EIAH in healthy young athletes...
  40. ncbi request reprint Neutrophils, myeloperoxidase, and bronchiectasis in cystic fibrosis: green is not good
    Keith C Meyer
    J Lab Clin Med 144:124-6. 2004