Kelly A N Messingham

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. pmc Functional characterization of an IgE-class monoclonal antibody specific for the bullous pemphigoid autoantigen, BP180
    Kelly A N Messingham
    Department of Dermatology, The University of Iowa, Iowa City, Iowa, USA
    Hybridoma (Larchmt) 31:111-7. 2012
  2. pmc A novel ELISA reveals high frequencies of BP180-specific IgE production in bullous pemphigoid
    Kelly A N Messingham
    The Department of Dermatology, University of Iowa, Iowa City, IA, USA
    J Immunol Methods 346:18-25. 2009
  3. doi request reprint FcR-independent effects of IgE and IgG autoantibodies in bullous pemphigoid
    Kelly N Messingham
    Department of Dermatology, University of Iowa, Iowa City, IA 52242, USA
    J Immunol 187:553-60. 2011
  4. doi request reprint Pregnant women have increased incidence of IgE autoantibodies reactive with the skin and placental antigen BP180 (type XVII collagen)
    Megan H Noe
    Department of Dermatology, University of Iowa, Iowa City, IA 52242, USA
    J Reprod Immunol 85:198-204. 2010

Collaborators

Detail Information

Publications4

  1. pmc Functional characterization of an IgE-class monoclonal antibody specific for the bullous pemphigoid autoantigen, BP180
    Kelly A N Messingham
    Department of Dermatology, The University of Iowa, Iowa City, Iowa, USA
    Hybridoma (Larchmt) 31:111-7. 2012
    ..We therefore expect that this MAb will prove to be a useful tool for dissecting the mechanisms used by BP180-NC16A-specific IgE antibodies in the induction of BP skin lesions...
  2. pmc A novel ELISA reveals high frequencies of BP180-specific IgE production in bullous pemphigoid
    Kelly A N Messingham
    The Department of Dermatology, University of Iowa, Iowa City, IA, USA
    J Immunol Methods 346:18-25. 2009
    ..Furthermore, we report that the majority of BP sera contain both IgE and IgG class autoantibodies specific for NC16A and suggest that screening for both isotypes of autoantibodies may provide a better diagnostic value than IgG alone...
  3. doi request reprint FcR-independent effects of IgE and IgG autoantibodies in bullous pemphigoid
    Kelly N Messingham
    Department of Dermatology, University of Iowa, Iowa City, IA 52242, USA
    J Immunol 187:553-60. 2011
    ..In addition, we provide evidence for an FcR-independent mechanism for both IgE and IgG class autoantibodies that could contribute to BP pathogenesis...
  4. doi request reprint Pregnant women have increased incidence of IgE autoantibodies reactive with the skin and placental antigen BP180 (type XVII collagen)
    Megan H Noe
    Department of Dermatology, University of Iowa, Iowa City, IA 52242, USA
    J Reprod Immunol 85:198-204. 2010
    ..We conclude that some pregnant women develop antibodies specific for BP180, and that these autoantibodies are capable of binding both CTB and the placental amnion, potentially affecting placental function...