ENRIQUE A contact MESRI
Affiliation: University of Miami
- Kaposi's sarcoma and its associated herpesvirusEnrique A Mesri
Viral Oncology Program, Developmental Center for AIDS Research, and Department of Microbiology and Immunology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, 1, 550 NW 10th Avenue, 109 Papanicolau Building, Miami, Florida 33136, USA
Nat Rev Cancer 10:707-19. 2010....
- Kaposi's sarcoma herpesvirus oncogenesis is a notch better in 3DEnrique A Mesri
Viral Oncology Program, Sylvester Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA
Cell Host Microbe 10:529-31. 2011..This reproduces patterns of KSHV gene expression and presence of mesenchymal KSHV-infected cells found in KS lesions, narrowing the gap between in vitro systems of infection and KSHV tumorigenesis...
- Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcomaQi Ma
Vascular Biology Institute, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA
Proc Natl Acad Sci U S A 106:8683-8. 2009..Our findings suggest host and viral genes triggering Rac1 or ROS production as key determinants of KS onset and potential KS chemopreventive or therapeutic targets...
- Efficacy of bortezomib in a direct xenograft model of primary effusion lymphomaKristopher A Sarosiek
Department of Molecular and Cellular Pharmacology, Division of Hematology Oncology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA
Proc Natl Acad Sci U S A 107:13069-74. 2010..Our findings show that this direct xenograft model can be used for testing novel PEL therapeutic strategies and also can provide a rational basis for evaluation of bortezomib in clinical trials...
- BIOLOGY OF HHV8/KSHV G PROTEIN COUPLED RECEPTORENRIQUE MESRI; Fiscal Year: 2002..The second is to discover high affinity, specific ligands for HHV-8 GPCR based on analogy to known chemokines. The third is to determine the roles of HHV-8 GPCR in disease pathogenesis. ..
- BIOLOGY OF KSHV/HHV8 G PROTEIN COUPLED RECEPTORENRIQUE MESRI; Fiscal Year: 2007..abstract_text> ..
- ROLE OF Rac AND REACTIVE OXYGEN SPECIES IN KAPOSI'S SARCOMA VIRAL ONCOGENESISENRIQUE A contact MESRI; Fiscal Year: 2010..So our work will allow us to not only to identify mechanisms of KS carcinogenesis but also will help to identify potential new target and new drugs for anti-KS therapy. ..
- BIOLOGY OF KSHV/HHV8 G PROTEIN COUPLED RECEPTORENRIQUE MESRI; Fiscal Year: 2009..abstract_text> ..