Sanaz Memarzadeh

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Urokinase plasminogen activator receptor: Prognostic biomarker for endometrial cancer
    Sanaz Memarzadeh
    Departments of Obstetrics and Gynecology, Pathology, and Medicine and Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 99:10647-52. 2002
  2. ncbi request reprint Lymphovascular and perineural invasion in the parametria: a prognostic factor for early-stage cervical cancer
    Sanaz Memarzadeh
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California 90095 1740, USA
    Obstet Gynecol 102:612-9. 2003
  3. doi request reprint Low Levels of Circulating Estrogen Sensitize PTEN-Null Endometrial Tumors to PARP Inhibition In Vivo
    Deanna M Janzen
    Corresponding Author Sanaz Memarzadeh, University of California, Los Angeles, 555 Westwood Plaza, Level B, Box 957243, 1015 Terasaki Life Sciences Building, Los Angeles, CA 90095
    Mol Cancer Ther 12:2917-28. 2013
  4. pmc Cell-autonomous activation of the PI3-kinase pathway initiates endometrial cancer from adult uterine epithelium
    Sanaz Memarzadeh
    Department of Obstetrics and Gynecology, The David Geffen School of Medicine, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 107:17298-303. 2010
  5. pmc Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal
    Sanaz Memarzadeh
    Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 108:7962-7. 2011
  6. pmc Estrogen and progesterone together expand murine endometrial epithelial progenitor cells
    Deanna M Janzen
    Department of Obstetrics and Gynecology, University of California, Los Angeles, California, USA
    Stem Cells 31:808-22. 2013
  7. doi request reprint Stem-like epithelial cells are concentrated in the distal end of the fallopian tube: a site for injury and serous cancer initiation
    Daniel Y Paik
    Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, California, USA
    Stem Cells 30:2487-97. 2012
  8. pmc Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptor
    Sanaz Memarzadeh
    Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
    Cancer Cell 12:572-85. 2007
  9. pmc Basal epithelial stem cells are efficient targets for prostate cancer initiation
    Devon A Lawson
    Department of Microbiology, The Howard Hughes Medical Institute, University of California, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 107:2610-5. 2010
  10. pmc Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy
    Deanna M Janzen
    Departments of Obstetrics and Gynecology, Molecular and Medical Pharmacology, and Molecular, Cell and Developmental Biology, David Geffen School of Medicine, Los Angeles, USA
    Cancer Res 73:4697-710. 2013

Collaborators

Detail Information

Publications13

  1. pmc Urokinase plasminogen activator receptor: Prognostic biomarker for endometrial cancer
    Sanaz Memarzadeh
    Departments of Obstetrics and Gynecology, Pathology, and Medicine and Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 99:10647-52. 2002
    ..034). Our data suggest that UPAR is a useful prognostic marker for biologically aggressive forms of endometrial cancer...
  2. ncbi request reprint Lymphovascular and perineural invasion in the parametria: a prognostic factor for early-stage cervical cancer
    Sanaz Memarzadeh
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California 90095 1740, USA
    Obstet Gynecol 102:612-9. 2003
    ..To estimate the impact of parametrial lymphovascular and perineural involvement on nodal metastasis and failure pattern of women with early-stage, surgically treated cervical cancer...
  3. doi request reprint Low Levels of Circulating Estrogen Sensitize PTEN-Null Endometrial Tumors to PARP Inhibition In Vivo
    Deanna M Janzen
    Corresponding Author Sanaz Memarzadeh, University of California, Los Angeles, 555 Westwood Plaza, Level B, Box 957243, 1015 Terasaki Life Sciences Building, Los Angeles, CA 90095
    Mol Cancer Ther 12:2917-28. 2013
    ..Extension of this work to clinical trials could personalize the therapy of women afflicted with advanced endometrial cancer using well-tolerated orally administered therapeutic agents. Mol Cancer Ther; 12(12); 2917-28. ©2013 AACR. ..
  4. pmc Cell-autonomous activation of the PI3-kinase pathway initiates endometrial cancer from adult uterine epithelium
    Sanaz Memarzadeh
    Department of Obstetrics and Gynecology, The David Geffen School of Medicine, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 107:17298-303. 2010
    ..This in vivo model provides an ideal platform for testing the response of endometrial carcinoma to targeted therapy against this common genetic alteration...
  5. pmc Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal
    Sanaz Memarzadeh
    Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 108:7962-7. 2011
    ..Insights into the role of hormone receptor signaling in the initiation of epithelial tumors may help define this axis as a target for chemoprevention of carcinomas...
  6. pmc Estrogen and progesterone together expand murine endometrial epithelial progenitor cells
    Deanna M Janzen
    Department of Obstetrics and Gynecology, University of California, Los Angeles, California, USA
    Stem Cells 31:808-22. 2013
    ..Discovery of signaling defects in endometrial epithelial progenitors or their niche can lead to development of better therapies in diseases of the endometrium...
  7. doi request reprint Stem-like epithelial cells are concentrated in the distal end of the fallopian tube: a site for injury and serous cancer initiation
    Daniel Y Paik
    Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, California, USA
    Stem Cells 30:2487-97. 2012
    ..These findings suggest that FTESC may play a role in the initiation of serous tumors. Characterization of these stem-like cells will provide new insight into how the FTE regenerate, respond to injury, and may initiate cancer...
  8. pmc Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptor
    Sanaz Memarzadeh
    Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
    Cancer Cell 12:572-85. 2007
    ..We also show that transient exposure to a paracrine growth factor may be sufficient for the initiation of oncogenic transformation...
  9. pmc Basal epithelial stem cells are efficient targets for prostate cancer initiation
    Devon A Lawson
    Department of Microbiology, The Howard Hughes Medical Institute, University of California, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 107:2610-5. 2010
    ..This finding provides evidence in support of basal epithelial stem cells as one target cell for prostate cancer initiation and demonstrates the propensity of primitive cells for tumorigenesis...
  10. pmc Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy
    Deanna M Janzen
    Departments of Obstetrics and Gynecology, Molecular and Medical Pharmacology, and Molecular, Cell and Developmental Biology, David Geffen School of Medicine, Los Angeles, USA
    Cancer Res 73:4697-710. 2013
    ..On the basis of these results, stromal expression of PR may emerge as a reliable biomarker in predicting response to hormonal therapy...
  11. pmc Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation
    Rita U Lukacs
    Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, 90095, USA
    Cell Stem Cell 7:682-93. 2010
    ..We conclude that Bmi-1 is a crucial regulator of self-renewal in adult prostate cells and plays important roles in prostate cancer initiation and progression...
  12. pmc Expression of colony-stimulating factor 1 receptor during prostate development and prostate cancer progression
    Hisamitsu Ide
    Howard Hughes Medical Institute, Department of Pathology and Laboratory Medicine, University of California, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 99:14404-9. 2002
    ..These observations correlate CSF-1R expression with changes in the growth and development of the normal and neoplastic prostate...
  13. pmc Differential transformation capacity of Src family kinases during the initiation of prostate cancer
    Houjian Cai
    Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 108:6579-84. 2011
    ..Our data indicate that development of inhibitors against specific SFK members could provide unique targeted therapeutic strategies...