Research Topics
| Ann J MelvinSummaryAffiliation: University of Washington Country: USA Publications
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Detail Information
Publications
Response to immunization with measles, tetanus, and Haemophilus influenzae type b vaccines in children who have human immunodeficiency virus type 1 infection and are treated with highly active antiretroviral therapyAnn J Melvin
Department of Pediatrics, University of Washington, Seattle, USA
Pediatrics 111:e641-4. 2003....
Rapid HIV type 1 testing of women presenting in late pregnancy with unknown HIV status in Lima, PeruAnn J Melvin
Department of Pediatrics, Division of Pediatric Infectious Disease, University of Washington, Seattle, Washington 98195, USA
AIDS Res Hum Retroviruses 20:1046-52. 2004..While HIV-1 testing early in pregnancy is preferable, rapid HIV-1 testing in late pregnancy or at delivery is feasible, acceptable to most women, and allows for timely intervention to reduce maternal-child transmission...
Cord blood lipids in infants born to HIV-1-infected women treated with combination antiretroviral therapyAnn J Melvin
Department of Pediatrics, University of Washington, Seattle, WA, USA
Antivir Ther 13:349-55. 2008....
Evidence that low-level viremias during effective highly active antiretroviral therapy result from two processes: expression of archival virus and replication of virusNicole H Tobin
Department of Pediatrics, University of Washington, Seattle, WA, USA
J Virol 79:9625-34. 2005..These observations provide a plausible explanation for the divergent clinical outcomes previously associated with LLV...
Increased mutations in Env and Pol suggest greater HIV-1 replication in sputum-derived viruses compared with blood-derived virusesThor A Wagner
University of Washington, Seattle, Washington, USA
AIDS 23:923-8. 2009..Our objective was to examine sputum, which is rich in macrophages, for evidence of increased HIV-1 replication compared with that in the blood during suppressive ART...
Density-dependent decay in HIV-1 dynamicsSarah E Holte
Division of Public Health, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, PO Box 19024, Seattle, WA 98109, USA
J Acquir Immune Defic Syndr 41:266-76. 2006..This suggests that conclusions about long-term viral dynamics of HIV infection based on simple exponential decay models should be carefully re-evaluated...
Multiple viral genetic analyses detect low-level human immunodeficiency virus type 1 replication during effective highly active antiretroviral therapyLisa M Frenkel
Department of Pediatrics, University of Washington, Seattle, Washington, USA
J Virol 77:5721-30. 2003..Furthermore, the decrease of cellular HIV-1 DNA to low absolute levels in those without genetic evidence of viral replication suggests that monitoring viral DNA during HAART may gauge low-level replication...
Effectiveness of antenatal group HIV voluntary counseling and testing services in rural IndiaDeepti Gupta
University of Washington School of Medicine, Seattle, USA
AIDS Educ Prev 19:187-97. 2007..Group counseling sessions achieve small gains in HIV knowledge, but there is a continued need for ongoing and multifaceted HIV education in rural India...
Incidence of noninfectious conditions in perinatally HIV-infected children and adolescents in the HAART eraSharon A Nachman
Department of Pediatrics, Stony Brook University Medical Center, Stony Brook, NY 11794 8111, USA
Arch Pediatr Adolesc Med 163:164-71. 2009....
Efficacy and toxicity of antiretroviral therapy using 4 or more agents: application of a strategy for antiretroviral management in human immunodeficiency virus-infected childrenAnn J Melvin
Department of Pediatrics, University of Washington, Seattle, USA
Arch Pediatr Adolesc Med 156:568-73. 2002..To characterize the long-term tolerance and virologic efficacy of combination antiretroviral therapy consisting of 4 or more agents in a clinical setting...
Virologic and immunologic correlates with the magnitude of antibody responses to the hepatitis A vaccine in HIV-infected children on highly active antiretroviral treatmentAdriana Weinberg
Department of Pediatrics, University of Colorado Denver, Aurora, CO 80045, USA
J Acquir Immune Defic Syndr 52:17-24. 2009..We sought to identify the immunologic and virologic factors associated with a robust response to hepatitis A virus (HAV) vaccine in children on highly active antiretroviral treatment...
Long-term effects of highly active antiretroviral therapy on CD4+ cell evolution among children and adolescents infected with HIV: 5 years and countingKunjal Patel
Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Clin Infect Dis 46:1751-60. 2008....
Association of hypercholesterolemia incidence with antiretroviral treatment, including protease inhibitors, among perinatally HIV-infected childrenKatherine Tassiopoulos
Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA 02115, USA
J Acquir Immune Defic Syndr 47:607-14. 2008..Antiretroviral therapy has been associated with hypercholesterolemia in HIV-infected children. Few longitudinal studies have been conducted to examine this association, however...
Safety and immunogenicity of an HIV-1 recombinant canarypox vaccine in newborns and infants of HIV-1-infected womenDaniel C Johnson
Sinai Children s Hospital and Rosalind Franklin University of Medicine and Science, North Chicago, IL 60608, USA
J Infect Dis 192:2129-33. 2005..33) TCID(50) vaccine formulation). Rare mucosal immunoglobulin A responses and no measurable vaccine-elicited serum antibodies were detected. In children, vCP205 appeared to be safe and immunogenic...
Association of site-specific and participant-specific factors with retention of children in a long-term pediatric HIV cohort studyPaige L Williams
Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA 02115 6017, USA
Am J Epidemiol 167:1375-86. 2008..Although participant characteristics are difficult to modify, the authors identified several potentially modifiable site practices that could be targeted to improve retention...
