Research Topics
Genomes and Genes | H MeisnerSummaryAffiliation: University of Massachusetts Medical Center Country: USA Publications
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Publications
Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell developmentH Meisner
Program in Molecular Medicine, University of Massachusetts Medical Center, Worcester 01605, USA
Mol Cell Biol 17:2217-25. 1997....
Coupling of the proto-oncogene product c-Cbl to the epidermal growth factor receptorH Meisner
Department of Biochemistry and Molecular Biology, University of Massachusetts Medical School, Worcester 01605, USA
J Biol Chem 270:25332-5. 1995..Such recruitment of Cbl to EGF receptors may reflect an important mechanism for its tyrosine phosphorylation and for assembling signaling components that mediate or modulate EGF actions...
Interactions of Cbl with Grb2 and phosphatidylinositol 3'-kinase in activated Jurkat cellsH Meisner
Department of Biochemistry and Molecular Biology, University of Massachusetts Medical School, Worcester 01605, USA
Mol Cell Biol 15:3571-8. 1995..Taken together, these data suggest that Cbl function in Jurkat T cells involves its constitutive association with Grb2 and its recruitment of PI 3-kinase in response to TCR activation...
Specific association of the beta isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto-oncogene c-cblD Hartley
Program in Molecular Medicine, University of Massachusetts Medical School, Worcester 01655, USA
J Biol Chem 270:18260-3. 1995..Thus, these results show important functional differences between the alpha and beta isoforms of p85 in vivo and point to c-cbl as a potentially important mediator of some of the functions of PI-3 kinase in intact cells...
A 115 kDa tyrosine phosphorylated protein associates with Grb-2 in activated Jurkat cellsH Meisner
Program in Molecular Medicine, University of Massachusetts Medical School, Worcester 01655, USA
Ann N Y Acad Sci 766:204-5. 1995
Cloning and characterization of a cDNA encoding the beta subunit of human casein kinase IIR A Heller-Harrison
Department of Biochemistry, University of Massachusetts Medical School, Worcester 01655
Biochemistry 28:9053-8. 1989..0 and 4.2 kb. Results from DNA analysis of HepG2 genomic DNA, consistent with results utilizing Drosophila genomic DNA, suggest the presence of a single gene for the beta subunit of casein kinase II...
