Rita S Mehta

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi Combination anastrozole and fulvestrant in metastatic breast cancer
    Rita S Mehta
    University of California Irvine Medical Center, Orange, CA 92868, USA
    N Engl J Med 367:435-44. 2012
  2. doi Rational and successful use of carboplatin and albumin-bound paclitaxel in a patient with recurrent metaplastic carcinoma who presented with multi-organ tumor emboli
    Rita S Mehta
    Department of Internal Medicine, University of California, Irvine, CA, USA
    Clin Breast Cancer 9:56-9. 2009
  3. pmc Predicting pathologic response to neoadjuvant chemotherapy in breast cancer by using MR imaging and quantitative 1H MR spectroscopy
    Hyeon Man Baek
    Tu and Yuen Center for Functional Onco Imaging, University of California, Irvine Hall 164, Irvine, CA 92697 5020, USA
    Radiology 251:653-62. 2009
  4. pmc Breast cancer: evaluation of response to neoadjuvant chemotherapy with 3.0-T MR imaging
    Jeon Hor Chen
    Tu and Yuen Center for Functional Onco Imaging and Department of Radiological Sciences, University of California, 164 Irvine Hall, Irvine, CA 92697 5020, USA
    Radiology 261:735-43. 2011
  5. ncbi The predictive value of sentinel lymph node biopsy in locally advanced breast cancer patients who have undergone neoadjuvant chemotherapy
    Maki Yamamoto
    University of California Irvine Medical Center, Orange, California 92868, USA
    Am Surg 73:977-80. 2007
  6. ncbi MRI evaluation of pathologically complete response and residual tumors in breast cancer after neoadjuvant chemotherapy
    Jeon Hor Chen
    Tu and Yuen Center for Functional Onco Imaging, University of California Irvine, Irvine, California 92697, USA
    Cancer 112:17-26. 2008
  7. pmc Residual breast cancer diagnosed by MRI in patients receiving neoadjuvant chemotherapy with and without bevacizumab
    Shadfar Bahri
    Tu and Yuen Center for Functional Onco Imaging, University of California, Irvine, USA
    Ann Surg Oncol 16:1619-28. 2009
  8. ncbi Predicting nodal status using dynamic contrast-enhanced magnetic resonance imaging in patients with locally advanced breast cancer undergoing neoadjuvant chemotherapy with and without sequential trastuzumab
    David J Hsiang
    Chao Family Comprehensive Cancer Center, University of California Irvine Medical Center, 101 The City Drive South, Bldg 56, Route 81, Orange, CA 92868, USA
    Arch Surg 142:855-61; discussion 860-1. 2007
  9. pmc Diagnostic performance of magnetic resonance imaging for assessing tumor response in patients with HER2-negative breast cancer receiving neoadjuvant chemotherapy is associated with molecular biomarker profile
    Aida Kuzucan
    John Tu and Thomas Yuen Center for Functional Onco Imaging of Department of Radiological Sciences, University of California, Irvine, California, USA
    Clin Breast Cancer 12:110-8. 2012
  10. pmc Impact of MRI-evaluated neoadjuvant chemotherapy response on change of surgical recommendation in breast cancer
    Jeon Hor Chen
    Tu and Yuen Center for Functional Onco Imaging, University of California, Irvine, California 92697 5020, USA
    Ann Surg 249:448-54. 2009

Detail Information

Publications25

  1. doi Combination anastrozole and fulvestrant in metastatic breast cancer
    Rita S Mehta
    University of California Irvine Medical Center, Orange, CA 92868, USA
    N Engl J Med 367:435-44. 2012
    ..We hypothesized that these two agents in combination might be more effective than anastrozole alone in patients with hormone-receptor (HR)-positive metastatic breast cancer...
  2. doi Rational and successful use of carboplatin and albumin-bound paclitaxel in a patient with recurrent metaplastic carcinoma who presented with multi-organ tumor emboli
    Rita S Mehta
    Department of Internal Medicine, University of California, Irvine, CA, USA
    Clin Breast Cancer 9:56-9. 2009
    ..Subsequently, the patient received carboplatin and albumin-bound paclitaxel and experienced complete remission...
  3. pmc Predicting pathologic response to neoadjuvant chemotherapy in breast cancer by using MR imaging and quantitative 1H MR spectroscopy
    Hyeon Man Baek
    Tu and Yuen Center for Functional Onco Imaging, University of California, Irvine Hall 164, Irvine, CA 92697 5020, USA
    Radiology 251:653-62. 2009
    ....
  4. pmc Breast cancer: evaluation of response to neoadjuvant chemotherapy with 3.0-T MR imaging
    Jeon Hor Chen
    Tu and Yuen Center for Functional Onco Imaging and Department of Radiological Sciences, University of California, 164 Irvine Hall, Irvine, CA 92697 5020, USA
    Radiology 261:735-43. 2011
    ..0-T magnetic resonance (MR) imaging...
  5. ncbi The predictive value of sentinel lymph node biopsy in locally advanced breast cancer patients who have undergone neoadjuvant chemotherapy
    Maki Yamamoto
    University of California Irvine Medical Center, Orange, California 92868, USA
    Am Surg 73:977-80. 2007
    ..Sentinel node biopsy is a viable option in patients who have undergone NAC. Her2/neu-positive patients who had undergone NAC with trastuzumab had comparable accuracy for sentinel node biopsy in predicting axillary node status...
  6. ncbi MRI evaluation of pathologically complete response and residual tumors in breast cancer after neoadjuvant chemotherapy
    Jeon Hor Chen
    Tu and Yuen Center for Functional Onco Imaging, University of California Irvine, Irvine, California 92697, USA
    Cancer 112:17-26. 2008
    ....
  7. pmc Residual breast cancer diagnosed by MRI in patients receiving neoadjuvant chemotherapy with and without bevacizumab
    Shadfar Bahri
    Tu and Yuen Center for Functional Onco Imaging, University of California, Irvine, USA
    Ann Surg Oncol 16:1619-28. 2009
    ..To investigate the impact of antiangiogenic therapy with bevacizumab on pathological response and the diagnostic performance of magnetic resonance imaging (MRI) in breast cancer patients...
  8. ncbi Predicting nodal status using dynamic contrast-enhanced magnetic resonance imaging in patients with locally advanced breast cancer undergoing neoadjuvant chemotherapy with and without sequential trastuzumab
    David J Hsiang
    Chao Family Comprehensive Cancer Center, University of California Irvine Medical Center, 101 The City Drive South, Bldg 56, Route 81, Orange, CA 92868, USA
    Arch Surg 142:855-61; discussion 860-1. 2007
    ..Dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) is a reliable and accurate method for monitoring primary tumor response in the breast and can be used as a surrogate to predict final axillary nodal status...
  9. pmc Diagnostic performance of magnetic resonance imaging for assessing tumor response in patients with HER2-negative breast cancer receiving neoadjuvant chemotherapy is associated with molecular biomarker profile
    Aida Kuzucan
    John Tu and Thomas Yuen Center for Functional Onco Imaging of Department of Radiological Sciences, University of California, Irvine, California, USA
    Clin Breast Cancer 12:110-8. 2012
    ....
  10. pmc Impact of MRI-evaluated neoadjuvant chemotherapy response on change of surgical recommendation in breast cancer
    Jeon Hor Chen
    Tu and Yuen Center for Functional Onco Imaging, University of California, Irvine, California 92697 5020, USA
    Ann Surg 249:448-54. 2009
    ..To investigate how MRI imaging of neoadjuvant chemotherapy (NAC) tumor response affects the recommendation for optimal breast cancer surgery, both before and after NAC...
  11. pmc Comparison of breast density measured on MR images acquired using fat-suppressed versus nonfat-suppressed sequences
    Daniel H E Chang
    Department of Radiological Sciences, University of California, Irvine, CA 92697, USA
    Med Phys 38:5961-8. 2011
    ..To investigate the difference of MR percent breast density measured from fat-suppressed versus nonfat-suppressed imaging sequences...
  12. ncbi MRI measurements of tumor size and pharmacokinetic parameters as early predictors of response in breast cancer patients undergoing neoadjuvant anthracycline chemotherapy
    Hon J Yu
    John Tu and Thomas Yuen Center for Functional Onco Imaging, University of California, Irvine, California 92697 5020, USA
    J Magn Reson Imaging 26:615-23. 2007
    ....
  13. pmc Diffuse optical spectroscopic imaging correlates with final pathological response in breast cancer neoadjuvant chemotherapy
    Albert E Cerussi
    Laser Microbeam and Medical Program, Beckman Laser Institute and Medical Clinic, University of California, Irvine, 1002 Health Sciences Road, East, Irvine, CA 92612, USA
    Philos Trans A Math Phys Eng Sci 369:4512-30. 2011
    ..This approach is well suited to monitoring breast tumour response and may provide feedback for optimizing therapeutic outcomes and minimizing side-effects...
  14. doi Impact of factors affecting the residual tumor size diagnosed by MRI following neoadjuvant chemotherapy in comparison to pathology
    Jeon Hor Chen
    Tu and Yuen Center for Functional Onco Imaging, Department of Radiological Sciences, University of California, Irvine, California Department of Radiology, E Da Hospital and I Shou University, Kaohsiung, Taiwan
    J Surg Oncol 109:158-67. 2014
    ..To investigate accuracy of magnetic resonance imaging (MRI) for measuring residual tumor size in breast cancer patients receiving neoadjuvant chemotherapy (NAC)...
  15. doi Risk of a second breast cancer associated with hormone-receptor and HER2/neu status of the first breast cancer
    Leona Bessonova
    Department of Epidemiology, University of California Irvine, Irvine, CA 92697, USA
    Cancer Epidemiol Biomarkers Prev 20:389-96. 2011
    ..Hormone-receptor (HR) and HER2/neu-receptor (HER2) status of breast tumors are important indicators for targeted therapies. We examine the association of receptor status and risk for a second breast cancer...
  16. pmc Spatial shrinkage/expansion patterns between breast density measured in two MRI scans evaluated by non-rigid registration
    Muqing Lin
    Tu and Yuen Center for Functional Onco Imaging, Department of Radiological Sciences, University of California, Irvine, CA, USA
    Phys Med Biol 56:5865-75. 2011
    ..The presented registration method can be further developed into a clinical tool for evaluating therapy-induced changes and for early diagnosis of breast cancer in screening MRI...
  17. ncbi Pathological complete response in triple negative poorly differentiated invasive ductal breast carcinoma detected during pregnancy
    Garima Agrawal
    Tu and Yuen Center for Functional Onco Imaging, University of California, Irvine, CA, USA
    J Clin Oncol 25:2618-20. 2007
  18. pmc Frequent optical imaging during breast cancer neoadjuvant chemotherapy reveals dynamic tumor physiology in an individual patient
    Albert E Cerussi
    Beckman Laser Institute, University of California, Irvine, 92612, USA
    Acad Radiol 17:1031-9. 2010
    ..Because optical methods provide functional imaging end points, our objective is to develop a low-barrier-to-access bedside approach that can be used for frequent, functional assessment of dynamic tumor physiology in individual patients...
  19. ncbi Comparison of choline and pharmacokinetic parameters in breast cancer measured by MR spectroscopic imaging and dynamic contrast enhanced MRI
    Min Ying Su
    John Tu and Thomas Yuen Center for Functional Onco Imaging, University of California, Irvine, CA 92697 5020, USA
    Technol Cancer Res Treat 5:401-10. 2006
    ..Since Choline is associated with cell replication and angiogenesis is required to support tumor growth, this might explain the correlation between these two sets of measures among different lesions...
  20. pmc Background parenchymal enhancement in the contralateral normal breast of patients undergoing neoadjuvant chemotherapy measured by DCE-MRI
    Jeon Hor Chen
    Tu and Yuen Center for Functional Onco Imaging, Department of Radiological Sciences, University of California, Irvine, CA, USA Department of Radiology, E Da Hospital and I Shou University, Kaohsiung 82445, Taiwan Electronic address
    Magn Reson Imaging 31:1465-71. 2013
    ..BPE was significantly decreased in F/U-2 MRI after NAC in women <55 years old. The reduction in BPE was most likely due to the ovarian ablation induced by chemotherapeutic agents...
  21. doi Need for a new treatment strategy: leptomeningeal carcinomatosis from gastric cancer
    Kavitha P Raj
    Department of Medicine, Chao Family Comprehensive Cancer Center, University of California, Irvine, 92868, USA
    Anticancer Drugs 20:301-4. 2009
    ..Our patient not only had an excellent tumor response to this novel approach, but also had a prolonged overall survival of 13 months, which is unusual for LMC from gastric cancer...
  22. ncbi Conservation of in vitro drug resistance patterns in epithelial ovarian carcinoma
    Krishnansu S Tewari
    The Division of Gynecologic Oncology, The Chao Family Comprehensive Cancer Center, University of California, Irvine Medical Center, 101 The City Drive, Orange, CA 92868, USA
    Gynecol Oncol 98:360-8. 2005
    ..To compare the in vitro drug resistance profiles of advanced stage primary and recurrent epithelial ovarian cancer specimens using the tritiated thymidine uptake assay...
  23. ncbi Measurement of volumetric and vascular changes with dynamic contrast enhanced MRI for cancer therapy monitoring
    Min Ying Su
    John Tu and Thomas Yuen Center for Functional Onco Imaging, University of California, Irvine Hall 164, Irvine, CA 92697, USA
    Technol Cancer Res Treat 1:479-88. 2002
    ..The vascular properties measured by macromolecular contrast medium may have the potential to serve as early therapeutic efficacy indicators...
  24. pmc Prognostic impact of human epidermal growth factor-like receptor 2 and hormone receptor status in inflammatory breast cancer (IBC): analysis of 2,014 IBC patient cases from the California Cancer Registry
    Jason A Zell
    Department of Epidemiology, Genetic Epidemiology Research Institute, School of Medicine, University of California Irvine, Irvine, CA 92697, USA
    Breast Cancer Res 11:R9. 2009
    ....
  25. doi A revised metric for quantifying body shape in vertebrates
    David C Collar
    Department of Ecology and Evolutionary Biology, Long Marine Laboratory, University of California, 100 Shaffer Road, Santa Cruz, CA 95060, USA
    Zoology (Jena) 116:246-57. 2013
    ..Altogether, our study highlights the promise VSI holds for identifying the morphological variation underlying body shape diversity as well as the selective factors driving shape evolution. ..