Research Topics
| J D MeekerSummaryAffiliation: University of Michigan Country: USA Publications
Research Grants
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Detail Information
Publications
An unrecognized source of PCB contamination in schools and other buildingsRobert F Herrick
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02215, USA
Environ Health Perspect 112:1051-3. 2004..The presence of PCBs in schools is of particular concern given evidence suggesting that PCBs are developmental toxins...
Exposure to nonpersistent insecticides and male reproductive hormonesJohn D Meeker
Department of Environmental Health, Occupational Health Program, Harvard School of Public Health, Building 1, Room 1405, 665 Huntington Avenue, Boston, Massachusetts 02115, USA
Epidemiology 17:61-8. 2006..CONCLUSION: In adult men, TCPY and 1N were associated with reduced testosterone levels. On a population level, these reductions are of potential public health importance because of widespread exposure to these nonpersistent insecticides...
Serum PCB levels and congener profiles among US construction workersRobert F Herrick
Harvard University School of Public Health, Huntington Ave, Boston MA, USA
Environ Health 6:25. 2007..Workers removing caulking material have been shown to have elevated serum PCB levels...
Cadmium, lead, and other metals in relation to semen quality: human evidence for molybdenum as a male reproductive toxicantJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan, USA
Environ Health Perspect 116:1473-9. 2008..g., zinc, copper) and nonessential (e.g., cadmium, lead), is inconsistent. Most studies to date used small sample sizes and were unable to account for important covariates...
Urinary metabolites of di(2-ethylhexyl) phthalate are associated with decreased steroid hormone levels in adult menJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, 6635 SPH Tower, 109 S Observatory St, Ann Arbor, MI 48109, USA
J Androl 30:287-97. 2009..In conclusion, these results suggest that urinary metabolites of DEHP are inversely associated with circulating steroid hormone levels in adult men. However, additional research is needed to confirm these findings...
Distribution, Variability, and Predictors of Urinary Concentrations of Phenols and Parabens among Pregnant Women in Puerto RicoJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan, United States
Environ Sci Technol 47:3439-47. 2013..Our results can inform future epidemiology studies and strategies to reduce exposure to these chemicals or their precursors...
Exposure to environmental endocrine disruptors and child developmentJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA
Arch Pediatr Adolesc Med 166:952-8. 2012....
Urinary phthalate metabolites and their biotransformation products: predictors and temporal variability among men and womenJohn D Meeker
Department of Environmental Health Sciences, University of Michigan, Ann Arbor, MI 48109, USA
J Expo Sci Environ Epidemiol 22:376-85. 2012..Conversely, the proportion of DEHP metabolites contributed to by MEHP was more stable within individuals over time and may be a promising indicator of susceptibility if time of day of sample collection is carefully considered...
Protocol of a randomized controlled trial of the Tobacco Tactics website for operating engineersSonia A Duffy
Department of Psychiatry, Ann Arbor VA Center for Clinical Management Research, The University of Michigan, School of Nursing, P O Box 130170, Ann Arbor, MI 48113 0170, USA
BMC Public Health 12:335. 2012..Process evaluation will compare the two groups on the: a) contacts with intervention; b) medications used; c) helpfulness of the nurse/coach; and d) willingness to recommend the intervention to others...
Bisphenol a exposure in Mexico City and risk of prematurity: a pilot nested case control studyDavid Cantonwine
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan, USA
Environ Health 9:62. 2010....
Phthalates and other additives in plastics: human exposure and associated health outcomesJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA
Philos Trans R Soc Lond B Biol Sci 364:2097-113. 2009..Recent advances in the measurement of exposure biomarkers hold much promise in improving the epidemiological data, but their utility must be understood to facilitate appropriate study design...
Serum and follicular fluid organochlorine concentrations among women undergoing assisted reproduction technologiesJohn D Meeker
Department of Environmental Health Sciences, University of Michigan, Ann Arbor, MI, USA
Environ Health 8:32. 2009....
Multiple metals predict prolactin and thyrotropin (TSH) levels in menJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, 6635 SPH Tower, 109 S Observatory St, Ann Arbor, MI 48109, USA
Environ Res 109:869-73. 2009..More research is needed for a better understanding of the role of metals in neuroendocrine and thyroid function and related health implications...
Exposure to environmental endocrine disrupting compounds and men's healthJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA
Maturitas 66:236-41. 2010....
Pyrethroid insecticide metabolites are associated with serum hormone levels in adult menJohn D Meeker
Department of Environmental Health Sciences, University of Michigan, Ann Arbor, MI, USA
Reprod Toxicol 27:155-60. 2009..09 and 0.05, respectively). The observed relationships were consistent with previous findings, but further research is needed for a better understanding of the potential association between pyrethroid insecticides and male reproduction...
Polybrominated diphenyl ether (PBDE) concentrations in house dust are related to hormone levels in menJohn D Meeker
Department of Environmental Health Sciences, University of Michigan, Ann Arbor, MI 48109, United States
Sci Total Environ 407:3425-9. 2009....
Engineering control technologies to reduce occupational silica exposures in masonry cutting and tuckpointingJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, 6635 SPH Tower, 109 S Observatory St, Ann Arbor, MI 48109, USA
Public Health Rep 124:101-11. 2009..This study evaluated the performance of commercially available engineering controls used in dusty construction tasks commonly performed by bricklayers...
Urinary phthalate metabolites in relation to preterm birth in Mexico cityJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan, USA
Environ Health Perspect 117:1587-92. 2009..Rates of preterm birth have been rising over the past several decades. Factors contributing to this trend remain largely unclear, and exposure to environmental contaminants may play a role...
Relationship between urinary phthalate and bisphenol A concentrations and serum thyroid measures in U.S. adults and adolescents from the National Health and Nutrition Examination Survey (NHANES) 2007-2008John D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan, USA
Environ Health Perspect 119:1396-402. 2011..Limited animal, in vitro, and human studies have reported that exposure to phthalates or bisphenol A (BPA) may affect thyroid signaling...
Serum concentrations of polychlorinated biphenyls in relation to in vitro fertilization outcomesJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan 48109, USA
Environ Health Perspect 119:1010-6. 2011..PCBs have been associated with adverse reproductive health outcomes including reduced fecundability and increased risk of pregnancy loss, although the human data remain largely inconclusive...
Urinary concentrations of parabens and serum hormone levels, semen quality parameters, and sperm DNA damageJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan 48109, USA
Environ Health Perspect 119:252-7. 2011..Widespread human exposure to parabens has been recently documented, and some parabens have demonstrated adverse effects on male reproduction in animal studies. However, human epidemiologic studies are lacking...
Hexavalent chromium exposure and control in welding tasksJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan 48109, USA
J Occup Environ Hyg 7:607-15. 2010..However, exposure could be substantially reduced with proper use of LEV...
Semen quality and sperm DNA damage in relation to urinary bisphenol A among men from an infertility clinicJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, 109 S Observatory St, Ann Arbor, MI 48109, USA
Reprod Toxicol 30:532-9. 2010..03%, 19%) increase in sperm DNA damage measured as the percentage of DNA in comet tail. In conclusion, urinary BPA may be associated with declined semen quality and increased sperm DNA damage, but confirmatory studies are needed...
Exposure to polychlorinated biphenyls (PCBs) and male reproductionJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA
Syst Biol Reprod Med 56:122-31. 2010....
House dust concentrations of organophosphate flame retardants in relation to hormone levels and semen quality parametersJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan 48109, USA
Environ Health Perspect 118:318-23. 2010..Although widespread human exposure to OP flame retardants is likely, there is a lack of human and animal data on potential health effects...
Urinary bisphenol A concentrations in relation to serum thyroid and reproductive hormone levels in men from an infertility clinicJohn D Meeker
Department of Environmental Health Sciences, University of Michigan, Ann Arbor, MI, USA
Environ Sci Technol 44:1458-63. 2010..Our results suggest that urinary BPA concentrations may be associated with altered hormone levels in men, but these findings need to be substantiated through further research...
Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenumJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan 48109, USA
Fertil Steril 93:130-40. 2010..To explore associations between exposure to metals and male reproductive hormone levels...
Human semen quality and sperm DNA damage in relation to urinary metabolites of pyrethroid insecticidesJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, 6635 SPH Tower, 109 S Observatory St, Ann Arbor, MI 48109, USA
Hum Reprod 23:1932-40. 2008..On the basis of limited studies, there is animal and human evidence for altered reproductive or endocrine function following pyrethroid exposure...
Thyroid hormones in relation to urinary metabolites of non-persistent insecticides in men of reproductive ageJohn D Meeker
Department of Environmental Health Sciences, University of Michigan, School of Public Health, M6226 SPH II, 109 S Observatory St, Ann Arbor, MI 48109, USA
Reprod Toxicol 22:437-42. 2006..There were no associations between 1N and thyroid hormones. Environmental exposure to chlorpyrifos, chlorpyrifos-methyl, or its metabolite TCPY may be associated with altered thyroid function in human males...
Utility of urinary 1-naphthol and 2-naphthol levels to assess environmental carbaryl and naphthalene exposure in an epidemiology studyJohn D Meeker
Department of Environmental Health Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA
J Expo Sci Environ Epidemiol 17:314-20. 2007..Conversely, studies of naphthalene-related outcomes may utilize 2N levels to estimate exposure...
Maternal exposure to second-hand tobacco smoke and pregnancy outcome among couples undergoing assisted reproductionJ D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA
Hum Reprod 22:337-45. 2007..Exposure to second-hand tobacco smoke is preventable, yet common. This study assessed relationships between maternal exposure to second-hand tobacco smoke and adverse pregnancy outcomes...
Relationships between serum hormone levels and semen quality among men from an infertility clinicJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI 48109, and Vincent Memorial Obstetrics and Gynecology Service, Massachusetts General Hospital, Boston, USA
J Androl 28:397-406. 2007..Additional consideration should be given to the utility of serum hormone levels as a surrogate for semen quality in epidemiologic studies in which the collection of semen is difficult due to logistical and/or volunteer rate constraints...
Serum PCBs, p,p'-DDE and HCB predict thyroid hormone levels in menJohn D Meeker
Department of Environmental Health Sciences, University of Michigan, M6226 SPH II, 109 S Observatory St, Ann Arbor, MI 48109, USA
Environ Res 104:296-304. 2007....
Risk of spontaneous abortion in women with childhood exposure to parental cigarette smokeJohn D Meeker
Department of Environmental Health Sciences, University of Michigan, Ann Arbor, MI 48109, USA
Am J Epidemiol 166:571-5. 2007..Future large studies of pregnancy loss are needed that can distinguish women's tobacco smoke exposure in childhood from that taking place in utero...
Di(2-ethylhexyl) phthalate metabolites may alter thyroid hormone levels in menJohn D Meeker
Department of Environmental Health Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA
Environ Health Perspect 115:1029-34. 2007..A limited number of animal studies suggest that exposure to phthalates may be associated with altered thyroid function, but human data are lacking...
Serum concentrations of estradiol and free T4 are inversely correlated with sperm DNA damage in men from an infertility clinicJohn D Meeker
Department of Environmental Health Sciences, University of Michigan School of Public Health, 6635 SPH Tower, 109 S Observatory St, Ann Arbor, MI 48109, USA
J Androl 29:379-88. 2008..These results suggest that estradiol and free T(4) may have a protective effect against sperm DNA damage, but future mechanistic and epidemiologic studies are needed to confirm these findings...
Circulating estradiol in men is inversely related to urinary metabolites of nonpersistent insecticidesJohn D Meeker
Department of Environmental Health Sciences, University of Michigan, School of Public Health, Ann Arbor, MI 48109, United States
Reprod Toxicol 25:184-91. 2008..Chlorpyrifos and carbaryl, nonpersistent insecticides to which the general population are commonly exposed, were recently shown to inhibit estradiol metabolism in vitro which could lead to altered hormone balance...
The relationship of urinary metabolites of carbaryl/naphthalene and chlorpyrifos with human semen qualityJohn D Meeker
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
Environ Health Perspect 112:1665-70. 2004....
Urinary levels of insecticide metabolites and DNA damage in human spermJohn D Meeker
Department of Environmental Health, Harvard School of Public Health, Massachusetts General Hospital, Boston, MA 02115, USA
Hum Reprod 19:2573-80. 2004..CONCLUSIONS: Environmental exposure to carbaryl and chlorpyrifos may be associated with increased DNA damage in human sperm, as indicated by a change in comet assay parameters...
DNA damage in human sperm is related to urinary levels of phthalate monoester and oxidative metabolitesR Hauser
Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
Hum Reprod 22:688-95. 2007....
Altered semen quality in relation to urinary concentrations of phthalate monoester and oxidative metabolitesRuss Hauser
Harvard School of Public Health Massachusetts General Hospital, Boston, MA 02115, USA
Epidemiology 17:682-91. 2006..The present study extends our work in a larger sample of men and includes measurements of di(2-ethylhexyl) phthalate (DEHP) oxidative metabolites...
Exposure to silica and metals among painters using specular hematite abrasiveJohn D Meeker
Harvard School of Public Health, Boston, Massachusetts, USA
J Occup Environ Hyg 2:D60-4. 2005
Physical and chemical characterization of asphalt (bitumen) paving exposuresRobert F Herrick
Harvard School of Public Health, Department of Environmental Health, Boston, Massachusetts 02215, USA
J Occup Environ Hyg 4:209-16. 2007..02 microm; count median diameter 0.24 microm)...
Manganese and welding fume exposure and control in constructionJohn D Meeker
Department of Environmental Health Sciences, University of Michigan, Ann Arbor, MI, USA
J Occup Environ Hyg 4:943-51. 2007..05) but only a 10% reduction in total particulate (geometric mean 4.5 mg/m(3) vs. 5.0 mg/m(3); p > 0.05). These results demonstrate that LEV use can reduce manganese exposure associated with welding tasks in construction...
Temporal variability of urinary phthalate metabolite levels in men of reproductive ageRuss Hauser
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
Environ Health Perspect 112:1734-40. 2004..In particular, a single urine sample was most predictive for MEP and least predictive for MEHP. These results suggest that the most efficient exposure assessment strategy for a particular study may depend on the phthalates of interest...
Comparison of occupational exposures among painters using three alternative blasting abrasivesJohn D Meeker
Department of Environmental Health Sciences, University of Michigan, Ann Arbor, USA
J Occup Environ Hyg 3:D80-4. 2006
Body mass index in relation to semen quality, sperm DNA integrity, and serum reproductive hormone levels among men attending an infertility clinicJorge E Chavarro
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Fertil Steril 93:2222-31. 2010..To examine the association between body weight and measures of male reproductive potential...
Temporal variability of urinary levels of nonpersistent insecticides in adult menJohn D Meeker
Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA
J Expo Anal Environ Epidemiol 15:271-81. 2005..In conclusion, although a single sample adequately predicted longer-term average exposure, a second sample collected at least 1 month following the first sample would reduce exposure measurement error...
Relationships between polybrominated diphenyl ether concentrations in house dust and serumPaula I Johnson
Department of Environmental Health Sciences, University of Michigan, Ann Arbor, Michigan, USA
Environ Sci Technol 44:5627-32. 2010..85, p = 0.0005). This study provides evidence that house dust is a primary exposure pathway of PBDEs and supports the use of dust PBDE concentrations as a marker for exposure to PBDE congeners other than BDE 153...
Occupational injuries among Boston bicycle messengersJack Tigh Dennerlein
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Am J Ind Med 42:519-25. 2002..Urban bicycle couriers may have a high incidence of injuries. Most messengers work as contractors and hence their injuries are not well documented...
Temporal variability and predictors of urinary bisphenol A concentrations in men and womenShruthi Mahalingaiah
Department of Obstetrics and Gynecology, Brigham and Women s Hospital, 665 Huntington Avenue, Boston, MA 02115, USA
Environ Health Perspect 116:173-8. 2008..Bisphenol A (BPA) is used to manufacture polymeric materials, such as polycarbonate plastics, and is found in a variety of consumer products. Recent data show widespread BPA exposure among the U.S. population...
Research Grants
- Bisphenol A and Phthalate Exposure in Relation to Fetal Growth and Preterm BirthJohn D Meeker; Fiscal Year: 2010....
