Amie L Meditz

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. pmc CCR5 expression is elevated on endocervical CD4+ T cells in healthy postmenopausal women
    Amie L Meditz
    Division of Infectious Diseases, Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA
    J Acquir Immune Defic Syndr 59:221-8. 2012
  2. pmc Sex, race, and geographic region influence clinical outcomes following primary HIV-1 infection
    Amie L Meditz
    Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA
    J Infect Dis 203:442-51. 2011
  3. pmc CCR5 expression is reduced in lymph nodes of HIV type 1-infected women, compared with men, but does not mediate sex-based differences in viral loads
    Amie L Meditz
    Division of Infectious Diseases, Department of Medicine
    J Infect Dis 209:922-30. 2014
  4. pmc SDF-1alpha is a potent inducer of HIV-1-Specific CD8+ T-cell chemotaxis, but migration of CD8+ T cells is impaired at high viral loads
    Amie L Meditz
    Division of Infectious Diseases, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    AIDS Res Hum Retroviruses 24:977-85. 2008
  5. pmc Blood myeloid dendritic cells from HIV-1-infected individuals display a proapoptotic profile characterized by decreased Bcl-2 levels and by caspase-3+ frequencies that are associated with levels of plasma viremia and T cell activation in an exploratory st
    Stephanie M Dillon
    Department of Medicine, University of Colorado Denver, Aurora, Colorado 80045, USA
    J Virol 85:397-409. 2011
  6. pmc Plasmacytoid and myeloid dendritic cells with a partial activation phenotype accumulate in lymphoid tissue during asymptomatic chronic HIV-1 infection
    Stephanie M Dillon
    Division of Infectious Diseases, Department of Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Acquir Immune Defic Syndr 48:1-12. 2008
  7. pmc Tumor necrosis factor-α inhibition improves endothelial function and decreases arterial stiffness in estrogen-deficient postmenopausal women
    Kerrie L Moreau
    Division of Geriatric Medicine, Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, USA Electronic address
    Atherosclerosis 230:390-6. 2013
  8. ncbi request reprint CTL fail to accumulate at sites of HIV-1 replication in lymphoid tissue
    Elizabeth Connick
    Division of Infectious Diseases, University of Colorado at Denver and Health Sciences Center, Denver, CO 80262, USA
    J Immunol 178:6975-83. 2007
  9. pmc HLA-DR+ CD38+ CD4+ T lymphocytes have elevated CCR5 expression and produce the majority of R5-tropic HIV-1 RNA in vivo
    Amie L Meditz
    Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA
    J Virol 85:10189-200. 2011
  10. pmc Effect of antacids on the pharmacokinetics of raltegravir in human immunodeficiency virus-seronegative volunteers
    Jennifer J Kiser
    Department of Pharmaceutical Sciences, University of Colorado Denver, 12700 E 19th Avenue, P15 C238, Research Complex 2, Aurora, CO 80045, USA
    Antimicrob Agents Chemother 54:4999-5003. 2010

Collaborators

Detail Information

Publications13

  1. pmc CCR5 expression is elevated on endocervical CD4+ T cells in healthy postmenopausal women
    Amie L Meditz
    Division of Infectious Diseases, Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA
    J Acquir Immune Defic Syndr 59:221-8. 2012
    ..Activated CD4+ T cells and CCR5 expression are linked to HIV-1 susceptibility, but whether these parameters are altered in the cervix of older women is unknown...
  2. pmc Sex, race, and geographic region influence clinical outcomes following primary HIV-1 infection
    Amie L Meditz
    Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA
    J Infect Dis 203:442-51. 2011
    ..It is unknown whether sex and race influence clinical outcomes following primary human immunodeficiency virus type 1 (HIV-1) infection...
  3. pmc CCR5 expression is reduced in lymph nodes of HIV type 1-infected women, compared with men, but does not mediate sex-based differences in viral loads
    Amie L Meditz
    Division of Infectious Diseases, Department of Medicine
    J Infect Dis 209:922-30. 2014
    ..Background: Human immunodeficiency virus type 1 (HIV-1)-infected women have lower viral loads than men but similar rates of disease progression. We hypothesized that sex-based differences in CCR5 expression mediate viral load differences...
  4. pmc SDF-1alpha is a potent inducer of HIV-1-Specific CD8+ T-cell chemotaxis, but migration of CD8+ T cells is impaired at high viral loads
    Amie L Meditz
    Division of Infectious Diseases, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    AIDS Res Hum Retroviruses 24:977-85. 2008
    ..Improved understanding of the determinants of CTL localization may provide insight into novel therapies to enhance delivery of CTL to sites of HIV-1 replication...
  5. pmc Blood myeloid dendritic cells from HIV-1-infected individuals display a proapoptotic profile characterized by decreased Bcl-2 levels and by caspase-3+ frequencies that are associated with levels of plasma viremia and T cell activation in an exploratory st
    Stephanie M Dillon
    Department of Medicine, University of Colorado Denver, Aurora, Colorado 80045, USA
    J Virol 85:397-409. 2011
    ....
  6. pmc Plasmacytoid and myeloid dendritic cells with a partial activation phenotype accumulate in lymphoid tissue during asymptomatic chronic HIV-1 infection
    Stephanie M Dillon
    Division of Infectious Diseases, Department of Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Acquir Immune Defic Syndr 48:1-12. 2008
    ..Activation and depletion of DCs in blood with accumulation in lymphoid tissue may contribute to HIV-associated chronic immune activation and T-cell dysfunction...
  7. pmc Tumor necrosis factor-α inhibition improves endothelial function and decreases arterial stiffness in estrogen-deficient postmenopausal women
    Kerrie L Moreau
    Division of Geriatric Medicine, Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO 80045, USA Electronic address
    Atherosclerosis 230:390-6. 2013
    ..We determined whether acute inhibition of TNF-α improves vascular endothelial function and decreases arterial stiffness in estrogen-deficient postmenopausal women...
  8. ncbi request reprint CTL fail to accumulate at sites of HIV-1 replication in lymphoid tissue
    Elizabeth Connick
    Division of Infectious Diseases, University of Colorado at Denver and Health Sciences Center, Denver, CO 80262, USA
    J Immunol 178:6975-83. 2007
    ..Mechanisms underlying the exclusion of CTL from lymphoid follicles as well as the role of lymphoid follicles in perpetuating other chronic pathogens merit further investigation...
  9. pmc HLA-DR+ CD38+ CD4+ T lymphocytes have elevated CCR5 expression and produce the majority of R5-tropic HIV-1 RNA in vivo
    Amie L Meditz
    Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA
    J Virol 85:10189-200. 2011
    ..PBMC assays failed to recapitulate in vivo findings, suggesting limited utility. Strategies to reduce numbers of DR(+) 38(+) CD4(+) T cells may substantially inhibit HIV-1 replication...
  10. pmc Effect of antacids on the pharmacokinetics of raltegravir in human immunodeficiency virus-seronegative volunteers
    Jennifer J Kiser
    Department of Pharmaceutical Sciences, University of Colorado Denver, 12700 E 19th Avenue, P15 C238, Research Complex 2, Aurora, CO 80045, USA
    Antimicrob Agents Chemother 54:4999-5003. 2010
    ....
  11. pmc Endothelial function is impaired across the stages of the menopause transition in healthy women
    Kerrie L Moreau
    Division of Geriatric Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado 80045, USA
    J Clin Endocrinol Metab 97:4692-700. 2012
    ..The stages of the menopause transition are characterized by changes in ovarian hormones and increased cardiovascular disease (CVD) risk factors and vasomotor symptoms that may adversely affect vascular health...
  12. ncbi request reprint Gender differences in AIDS-associated Kaposi sarcoma in Harare, Zimbabwe
    Amie L Meditz
    Division of Infectious Diseases, Department of Medicine, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
    J Acquir Immune Defic Syndr 44:306-8. 2007
    ..7, 95% confidence interval: 1.1 to 2.7; P = 0.009). These findings suggest an increased severity of KS or other unidentified infections among women with AIDS-KS in Zimbabwe...
  13. ncbi request reprint alpha-Defensins 1, 2, and 3 are expressed by granulocytes in lymphoid tissues of HIV-1-seropositive and -seronegative individuals
    Joy M Folkvord
    Department of Medicine, Division of Infectious Diseases, University of Colorado Health Sciences Center, Denver, 80262, USA
    J Acquir Immune Defic Syndr 42:529-36. 2006
    ..The role of alpha-defensins in controlling HIV-1 replication merits further investigation...