Felipe A Medeiros
Affiliation: University of California
Medeiros F, Lisboa R, Weinreb R, Girkin C, Liebmann J, Zangwill L. A combined index of structure and function for staging glaucomatous damage. Arch Ophthalmol. 2012;130:1107-16 pubmed
..An index combining structure and function performed better than isolated structural and functional measures for detection of perimetric and preperimetric glaucoma as well as for discriminating different stages of the disease. ..
Tatham A, Weinreb R, Zangwill L, Liebmann J, Girkin C, Medeiros F. Estimated retinal ganglion cell counts in glaucomatous eyes with localized retinal nerve fiber layer defects. Am J Ophthalmol. 2013;156:578-587.e1 pubmed publisher
..001) and higher than in healthy eyes (1 ± 13%; P < .001). Although visible localized RNFL defects often are considered an early sign of glaucoma, this study indicates that they are likely to be associated with large neuronal losses. ..
Medeiros F, Lisboa R, Zangwill L, Liebmann J, Girkin C, Bowd C, et al
. Evaluation of progressive neuroretinal rim loss as a surrogate end point for development of visual field loss in glaucoma. Ophthalmology. 2014;121:100-109 pubmed publisher
..These findings suggest that rim area measurements may be suitable surrogate end points in glaucoma clinical trials. ..
Tatham A, Miki A, Weinreb R, Zangwill L, Medeiros F. Defects of the lamina cribrosa in eyes with localized retinal nerve fiber layer loss. Ophthalmology. 2014;121:110-118 pubmed publisher
..72; 95% CI, 0.44-1.00; P<0.001). Focal defects of the LC were frequently visible in glaucomatous eyes with localized RNFL defects. Focal abnormalities of the LC may be associated with focal retinal nerve fiber damage. ..
Medeiros F, Weinreb R, R Boer E, Rosen P. Driving simulation as a performance-based test of visual impairment in glaucoma. J Glaucoma. 2012;21:221-7 pubmed publisher
Medeiros F, Zangwill L, Anderson D, Liebmann J, Girkin C, Harwerth R, et al
. Estimating the rate of retinal ganglion cell loss in glaucoma. Am J Ophthalmol. 2012;154:814-824.e1 pubmed publisher
..The rate of RGC loss estimated from combining structure and function performed better than either isolated structural or functional measures for detecting progressive glaucomatous damage. ..
Meira Freitas D, Tatham A, Lisboa R, Kuang T, Zangwill L, Weinreb R, et al
. Predicting progression of glaucoma from rates of frequency doubling technology perimetry change. Ophthalmology. 2014;121:498-507 pubmed publisher
..This finding suggests that longitudinal FDT evaluation may be useful for risk stratification of patients with suspected glaucoma. ..
Tatham A, Meira Freitas D, Weinreb R, Zangwill L, Medeiros F. Detecting glaucoma using automated pupillography. Ophthalmology. 2014;121:1185-93 pubmed publisher
..74. Although the pupillograph had a good ability to detect glaucoma in the presence of asymmetric disease, it performed poorly in those with symmetric disease. ..
Liu T, Tatham A, Gracitelli C, Zangwill L, Weinreb R, Medeiros F. Rates of Retinal Nerve Fiber Layer Loss inÂ Contralateral Eyes of Glaucoma Patients with Unilateral Progression by Conventional Methods. Ophthalmology. 2015;122:2243-51 pubmed publisher
..These findings indicate that assessment of RNFL thickness by SD OCT may show progressive glaucomatous damage that is not detected by visual fields or optic disc stereophotography. ..