Patrick McQuillen

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Balloon atrial septostomy is associated with preoperative stroke in neonates with transposition of the great arteries
    Patrick S McQuillen
    Pediatric Heart Center, University of California, San Francisco, USA
    Circulation 113:280-5. 2006
  2. ncbi request reprint Erythropoietin enhances long-term neuroprotection and neurogenesis in neonatal stroke
    Fernando F Gonzalez
    Department of Pediatrics, University of California, San Francisco, Calif 94143 0663, USA
    Dev Neurosci 29:321-30. 2007
  3. doi request reprint Altered fate of subventricular zone progenitor cells and reduced neurogenesis following neonatal stroke
    Ruggero Spadafora
    Department of Neurology, University of California, San Francisco, CA 94143 0663, USA
    Dev Neurosci 32:101-13. 2010
  4. ncbi request reprint Hippocampal and visuospatial learning defects in mice with a deletion of frizzled 9, a gene in the Williams syndrome deletion interval
    Chunjie Zhao
    Department of Neurology, Graduate Programs in Neuroscience, Developmental Biology and Biomedical Sciences, Room S 268, 513 Parnassus Avenue, University of California, San Francisco, CA 94143, USA
    Development 132:2917-27. 2005
  5. ncbi request reprint Preoperative brain injury in newborns with transposition of the great arteries
    Steven P Miller
    Department of Pediatrics, University of California, San Francisco, CA 94143 0663, USA
    Ann Thorac Surg 77:1698-706. 2004
  6. ncbi request reprint Abnormal brain development in newborns with congenital heart disease
    Steven P Miller
    Department of Neurology, University of California at San Francisco, San Francisco, USA
    N Engl J Med 357:1928-38. 2007
  7. ncbi request reprint Selective vulnerability of subplate neurons after early neonatal hypoxia-ischemia
    Patrick S McQuillen
    Department of Pediatrics, University of California San Francisco Medical Center, San Francisco, California 94143 0106, USA
    J Neurosci 23:3308-15. 2003
  8. ncbi request reprint A novel role for p75NTR in subplate growth cone complexity and visual thalamocortical innervation
    Patrick S McQuillen
    Department of Pediatrics, University of California, San Francisco Medical Center, San Francisco, California 94143, USA
    J Neurosci 22:3580-93. 2002
  9. ncbi request reprint Erythropoietin improves functional and histological outcome in neonatal stroke
    Yun Sil Chang
    Departments of Neurology and Pediatrics, University of California San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0663, USA
    Pediatr Res 58:106-11. 2005
  10. ncbi request reprint Pyramidal tract maturation after brain injury in newborns with heart disease
    Savannah C Partridge
    Department of Radiology, University of California, San Francisco, San Francisco, CA, USA
    Ann Neurol 59:640-51. 2006

Research Grants

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Balloon atrial septostomy is associated with preoperative stroke in neonates with transposition of the great arteries
    Patrick S McQuillen
    Pediatric Heart Center, University of California, San Francisco, USA
    Circulation 113:280-5. 2006
    ..Preoperative brain injury is common in neonates with transposition of the great arteries (TGA). The objective of this study is to determine risk factors for preoperative brain injury in neonates with TGA...
  2. ncbi request reprint Erythropoietin enhances long-term neuroprotection and neurogenesis in neonatal stroke
    Fernando F Gonzalez
    Department of Pediatrics, University of California, San Francisco, Calif 94143 0663, USA
    Dev Neurosci 29:321-30. 2007
    ..These results suggest that EPO may neuroprotect and direct cell fate toward neurogenesis and away from gliogenesis in neonatal stroke...
  3. doi request reprint Altered fate of subventricular zone progenitor cells and reduced neurogenesis following neonatal stroke
    Ruggero Spadafora
    Department of Neurology, University of California, San Francisco, CA 94143 0663, USA
    Dev Neurosci 32:101-13. 2010
    ..To investigate the effects of neonatal stroke on progenitor cells lining the lateral ventricles...
  4. ncbi request reprint Hippocampal and visuospatial learning defects in mice with a deletion of frizzled 9, a gene in the Williams syndrome deletion interval
    Chunjie Zhao
    Department of Neurology, Graduate Programs in Neuroscience, Developmental Biology and Biomedical Sciences, Room S 268, 513 Parnassus Avenue, University of California, San Francisco, CA 94143, USA
    Development 132:2917-27. 2005
    ..We conclude that frizzled 9 is a critical determinant of hippocampal development and is very likely to be a contributing factor to the neurodevelopmental and behavioral phenotype of patients with Williams syndrome...
  5. ncbi request reprint Preoperative brain injury in newborns with transposition of the great arteries
    Steven P Miller
    Department of Pediatrics, University of California, San Francisco, CA 94143 0663, USA
    Ann Thorac Surg 77:1698-706. 2004
    ....
  6. ncbi request reprint Abnormal brain development in newborns with congenital heart disease
    Steven P Miller
    Department of Neurology, University of California at San Francisco, San Francisco, USA
    N Engl J Med 357:1928-38. 2007
    ..We characterized brain metabolism and microstructure, as measures of brain maturation, in newborns with congenital heart disease before they underwent heart surgery...
  7. ncbi request reprint Selective vulnerability of subplate neurons after early neonatal hypoxia-ischemia
    Patrick S McQuillen
    Department of Pediatrics, University of California San Francisco Medical Center, San Francisco, California 94143 0106, USA
    J Neurosci 23:3308-15. 2003
    ..However, deficits in motor function still occur, as in babies with PVL. Subplate neuron cell death in PVL provides another mechanism for abnormal neurodevelopment after neonatal hypoxia-ischemia...
  8. ncbi request reprint A novel role for p75NTR in subplate growth cone complexity and visual thalamocortical innervation
    Patrick S McQuillen
    Department of Pediatrics, University of California, San Francisco Medical Center, San Francisco, California 94143, USA
    J Neurosci 22:3580-93. 2002
    ..Our present results are unusual in that they argue that p75NTR functions in a novel way in subplate neurons, that is, in growth cone morphology and function rather than in axon extension or neuronal survival...
  9. ncbi request reprint Erythropoietin improves functional and histological outcome in neonatal stroke
    Yun Sil Chang
    Departments of Neurology and Pediatrics, University of California San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0663, USA
    Pediatr Res 58:106-11. 2005
    ..This functional improvement directly correlated with the amount of preserved hemispheric volume. These results suggest EPO may be a candidate in the treatment of neonatal stroke...
  10. ncbi request reprint Pyramidal tract maturation after brain injury in newborns with heart disease
    Savannah C Partridge
    Department of Radiology, University of California, San Francisco, San Francisco, CA, USA
    Ann Neurol 59:640-51. 2006
    ..Our objective was to quantify white matter tract development in term newborns with congenital heart disease, a population at high risk for perioperative brain injury, using magnetic resonance imaging diffusion tensor tractography (DTT)...
  11. ncbi request reprint Selective vulnerability in the developing central nervous system
    Patrick S McQuillen
    Department of Pediatrics, University of California San Francisco Medical Center, San Francisco, California 94143 0106, USA
    Pediatr Neurol 30:227-35. 2004
    ..The unique roles of particular mechanisms including oxidative stress, glutamatergic neurotransmission, and programmed cell death are discussed in the context of this selective vulnerability...
  12. pmc Neurology of congenital heart disease: insight from brain imaging
    Steven P Miller
    University of British Columbia, BC Children s Hospital, Division of Neurology, K3 180, 4480 Oak Street, Vancouver BC V6H 3V4 Canada
    Arch Dis Child Fetal Neonatal Ed 92:F435-7. 2007
  13. ncbi request reprint Temporal and anatomic risk profile of brain injury with neonatal repair of congenital heart defects
    Patrick S McQuillen
    Pediatric Heart Center, University of California at San Francisco, San Francisco, CA, USA
    Stroke 38:736-41. 2007
    ..The purpose of this study is to define the risk factors for preoperative and postoperative brain injuries and their association with functional cardiac anatomic groups...

Research Grants8

  1. SUBPLATE NEURONS AND EARLY HYPOXIC ISCHEMIC BRAIN INJURY
    Patrick McQuillen; Fiscal Year: 2002
    ....
  2. Selective subplate vulnerability and cortical plasticity
    Patrick McQuillen; Fiscal Year: 2007
    ..Finally, we hypothesize that treatments that protect sub-plate neurons in vitro will also prevent sub-plate neuron cell death following early hypoxia ischemia. ..
  3. Critical Period Plasticity Following Neonatal Brain Injury
    Patrick Sean McQuillen; Fiscal Year: 2010
    ..Understanding plasticity following injury will provide both a new outcome measure and a model to guide therapy for recovering brain function. ..
  4. White Matter Injury in Critical Ill Newborns With Congenital Heart Disease
    Patrick Sean McQuillen; Fiscal Year: 2010
    ..Page McQuillen, Patrick S. ..