Affiliation: University of California
- Balloon atrial septostomy is associated with preoperative stroke in neonates with transposition of the great arteriesPatrick S McQuillen
Pediatric Heart Center, University of California, San Francisco, USA
Circulation 113:280-5. 2006..Preoperative brain injury is common in neonates with transposition of the great arteries (TGA). The objective of this study is to determine risk factors for preoperative brain injury in neonates with TGA...
- Erythropoietin enhances long-term neuroprotection and neurogenesis in neonatal strokeFernando F Gonzalez
Department of Pediatrics, University of California, San Francisco, Calif 94143 0663, USA
Dev Neurosci 29:321-30. 2007..These results suggest that EPO may neuroprotect and direct cell fate toward neurogenesis and away from gliogenesis in neonatal stroke...
- Altered fate of subventricular zone progenitor cells and reduced neurogenesis following neonatal strokeRuggero Spadafora
Department of Neurology, University of California, San Francisco, CA 94143 0663, USA
Dev Neurosci 32:101-13. 2010..To investigate the effects of neonatal stroke on progenitor cells lining the lateral ventricles...
- Hippocampal and visuospatial learning defects in mice with a deletion of frizzled 9, a gene in the Williams syndrome deletion intervalChunjie Zhao
Department of Neurology, Graduate Programs in Neuroscience, Developmental Biology and Biomedical Sciences, Room S 268, 513 Parnassus Avenue, University of California, San Francisco, CA 94143, USA
Development 132:2917-27. 2005..We conclude that frizzled 9 is a critical determinant of hippocampal development and is very likely to be a contributing factor to the neurodevelopmental and behavioral phenotype of patients with Williams syndrome...
- Preoperative brain injury in newborns with transposition of the great arteriesSteven P Miller
Department of Pediatrics, University of California, San Francisco, CA 94143 0663, USA
Ann Thorac Surg 77:1698-706. 2004....
- Abnormal brain development in newborns with congenital heart diseaseSteven P Miller
Department of Neurology, University of California at San Francisco, San Francisco, USA
N Engl J Med 357:1928-38. 2007..We characterized brain metabolism and microstructure, as measures of brain maturation, in newborns with congenital heart disease before they underwent heart surgery...
- Selective vulnerability of subplate neurons after early neonatal hypoxia-ischemiaPatrick S McQuillen
Department of Pediatrics, University of California San Francisco Medical Center, San Francisco, California 94143 0106, USA
J Neurosci 23:3308-15. 2003..However, deficits in motor function still occur, as in babies with PVL. Subplate neuron cell death in PVL provides another mechanism for abnormal neurodevelopment after neonatal hypoxia-ischemia...
- A novel role for p75NTR in subplate growth cone complexity and visual thalamocortical innervationPatrick S McQuillen
Department of Pediatrics, University of California, San Francisco Medical Center, San Francisco, California 94143, USA
J Neurosci 22:3580-93. 2002..Our present results are unusual in that they argue that p75NTR functions in a novel way in subplate neurons, that is, in growth cone morphology and function rather than in axon extension or neuronal survival...
- Erythropoietin improves functional and histological outcome in neonatal strokeYun Sil Chang
Departments of Neurology and Pediatrics, University of California-San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143-0663, USA
Pediatr Res 58:106-11. 2005..This functional improvement directly correlated with the amount of preserved hemispheric volume. These results suggest EPO may be a candidate in the treatment of neonatal stroke...
- Pyramidal tract maturation after brain injury in newborns with heart diseaseSavannah C Partridge
Department of Radiology, University of California, San Francisco, San Francisco, CA, USA
Ann Neurol 59:640-51. 2006..INTERPRETATION: DTT is feasible in term newborns and may help to characterize abnormal white matter tract development following acquired brain injury...
- Selective vulnerability in the developing central nervous systemPatrick S McQuillen
Department of Pediatrics, University of California San Francisco Medical Center, San Francisco, California 94143-0106, USA
Pediatr Neurol 30:227-35. 2004..The unique roles of particular mechanisms including oxidative stress, glutamatergic neurotransmission, and programmed cell death are discussed in the context of this selective vulnerability...
- Neurology of congenital heart disease: insight from brain imagingSteven P Miller
University of British Columbia, BC Children's Hospital, Division of Neurology, K3-180, 4480 Oak Street, Vancouver BC V6H 3V4 Canada
Arch Dis Child Fetal Neonatal Ed 92:F435-7. 2007
- Temporal and anatomic risk profile of brain injury with neonatal repair of congenital heart defectsPatrick S McQuillen
Pediatric Heart Center, University of California at San Francisco, San Francisco, CA, USA
Stroke 38:736-41. 2007..The purpose of this study is to define the risk factors for preoperative and postoperative brain injuries and their association with functional cardiac anatomic groups...
- SUBPLATE NEURONS AND EARLY HYPOXIC ISCHEMIC BRAIN INJURYPatrick McQuillen; Fiscal Year: 2002....
- Selective subplate vulnerability and cortical plasticityPatrick McQuillen; Fiscal Year: 2007..Finally, we hypothesize that treatments that protect sub-plate neurons in vitro will also prevent sub-plate neuron cell death following early hypoxia ischemia. ..
- Critical Period Plasticity Following Neonatal Brain InjuryPatrick Sean McQuillen; Fiscal Year: 2010..Understanding plasticity following injury will provide both a new outcome measure and a model to guide therapy for recovering brain function. ..
- White Matter Injury in Critical Ill Newborns With Congenital Heart DiseasePatrick Sean McQuillen; Fiscal Year: 2010..Page McQuillen, Patrick S. ..