Elizabeth McNally

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. doi request reprint Modifiers of heart and muscle function: where genetics meets physiology
    Kayleigh A Swaggart
    5841 South Maryland Avenue, MC 6088, Chicago, IL 606377, USA
    Exp Physiol 99:621-6. 2014
  2. pmc Genetic mutations and mechanisms in dilated cardiomyopathy
    Elizabeth M McNally
    Department of Human Genetics, University of Chicago, Chicago, Illinois 60637, USA
    J Clin Invest 123:19-26. 2013
  3. pmc The superhealing MRL background improves muscular dystrophy
    Ahlke Heydemann
    Department of Medicine, Section of Cardiology, 5841 S, Maryland, MC 6088, Chicago, IL, 60637, USA
    Skelet Muscle 2:26. 2012
  4. pmc The attachment disorders of muscle: failure to carb-load
    Elizabeth M McNally
    Department of Medicine, The University of Chicago, Chicago, IL 60637, USA
    J Clin Invest 122:3046-8. 2012
  5. pmc Interplay between heart and skeletal muscle disease in heart failure: the 2011 George E. Brown Memorial Lecture
    Elizabeth M McNally
    Department of Medicine, University of Chicago, Chicago, IL 60637, USA
    Circ Res 110:749-54. 2012
  6. doi request reprint Sarcomere mutations in cardiogenesis and ventricular noncompaction
    Elizabeth McNally
    Department of Medicine, Section of Cardiology, The University of Chicago, Chicago, IL 60637, USA
    Trends Cardiovasc Med 19:17-21. 2009
  7. pmc Altered chromosomal positioning, compaction, and gene expression with a lamin A/C gene mutation
    Stephanie K Mewborn
    Department of Medicine, The University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 5:e14342. 2010
  8. ncbi request reprint Cytoskeletal defects in cardiomyopathy
    Elizabeth McNally
    Department of Medicine, The University of Chicago, 5841 S Maryland, MC6088, Chicago, IL, USA
    J Mol Cell Cardiol 35:231-41. 2003
  9. pmc NO more muscle fatigue
    Ahlke Heydemann
    Section of Cardiology, Department of Medicine, University of Chicago, 5841 S Maryland, Chicago, IL 60637, USA
    J Clin Invest 119:448-50. 2009
  10. pmc Myoferlin is required for insulin-like growth factor response and muscle growth
    Alexis R Demonbreun
    Committee on Developmental Biology, The University of Chicago, Chicago, Illinois, USA
    FASEB J 24:1284-95. 2010

Collaborators

  • Harinder Singh
  • Kayleigh A Swaggart
  • Ahlke Heydemann
  • Peter Pytel
  • Alexis R Demonbreun
  • Stephanie K Mewborn
  • Michele Hadhazy
  • Gene H Kim
  • Jenan Holley-Cuthrell
  • Yuan Zhang
  • Heather MacLeod
  • Judy U Earley
  • Christine M Labno
  • Konstantina Heretis
  • Avery D Posey
  • John P Fahrenbach
  • Lisa Dellefave
  • Sara Selig
  • Karen Reddy
  • Megan J Puckelwartz
  • Fida Abuisneineh

Detail Information

Publications10

  1. doi request reprint Modifiers of heart and muscle function: where genetics meets physiology
    Kayleigh A Swaggart
    5841 South Maryland Avenue, MC 6088, Chicago, IL 606377, USA
    Exp Physiol 99:621-6. 2014
    ..In the human muscle disease Duchenne muscular dystrophy, protein coding single-nucleotide polymorphisms in LTBP4 associate with prolonged ambulation, demonstrating that modifiers identified from mouse studies translate to human disease. ..
  2. pmc Genetic mutations and mechanisms in dilated cardiomyopathy
    Elizabeth M McNally
    Department of Human Genetics, University of Chicago, Chicago, Illinois 60637, USA
    J Clin Invest 123:19-26. 2013
    ..Relatively few clinical clues guide the diagnosis of inherited DCM, but emerging evidence supports the use of genetic testing to identify those patients at risk for faster disease progression, congestive heart failure, and arrhythmia...
  3. pmc The superhealing MRL background improves muscular dystrophy
    Ahlke Heydemann
    Department of Medicine, Section of Cardiology, 5841 S, Maryland, MC 6088, Chicago, IL, 60637, USA
    Skelet Muscle 2:26. 2012
    ..abstract:..
  4. pmc The attachment disorders of muscle: failure to carb-load
    Elizabeth M McNally
    Department of Medicine, The University of Chicago, Chicago, IL 60637, USA
    J Clin Invest 122:3046-8. 2012
    ..In this issue of the JCI, Beedle et al. used conditional gene targeting of Fktn, the gene responsible for Fukuyama congenital muscular dystrophy, to investigate a developmental requirement for glycosylation of dystroglycan...
  5. pmc Interplay between heart and skeletal muscle disease in heart failure: the 2011 George E. Brown Memorial Lecture
    Elizabeth M McNally
    Department of Medicine, University of Chicago, Chicago, IL 60637, USA
    Circ Res 110:749-54. 2012
    ..Together, these studies demonstrate the value of using a genetically sensitized model to uncover pathways that regulate heart failure and muscle weakness...
  6. doi request reprint Sarcomere mutations in cardiogenesis and ventricular noncompaction
    Elizabeth McNally
    Department of Medicine, Section of Cardiology, The University of Chicago, Chicago, IL 60637, USA
    Trends Cardiovasc Med 19:17-21. 2009
    ..These human genetic findings support that normal myocardial and sarcomere function are required for proper compaction and septation and that these mutations also portend a high risk of developing heart failure in later life...
  7. pmc Altered chromosomal positioning, compaction, and gene expression with a lamin A/C gene mutation
    Stephanie K Mewborn
    Department of Medicine, The University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 5:e14342. 2010
    ..The nuclear lamina is thought to regulate gene expression by its direct interaction with chromatin. LMNA gene mutations may mediate disease by disrupting normal gene expression...
  8. ncbi request reprint Cytoskeletal defects in cardiomyopathy
    Elizabeth McNally
    Department of Medicine, The University of Chicago, 5841 S Maryland, MC6088, Chicago, IL, USA
    J Mol Cell Cardiol 35:231-41. 2003
    ..In this review, we will examine the genetic defects that lead to cardiomyopathy and the potential means by which these varied proteins normally maintain the structural integrity of myocytes...
  9. pmc NO more muscle fatigue
    Ahlke Heydemann
    Section of Cardiology, Department of Medicine, University of Chicago, 5841 S Maryland, Chicago, IL 60637, USA
    J Clin Invest 119:448-50. 2009
    ..Collectively, these findings significantly advance our understanding of exercise-induced muscle fatigue and its role in muscle disease...
  10. pmc Myoferlin is required for insulin-like growth factor response and muscle growth
    Alexis R Demonbreun
    Committee on Developmental Biology, The University of Chicago, Chicago, Illinois, USA
    FASEB J 24:1284-95. 2010
    ..Demonbreun, A. R., Posey, A. D., Heretis, K., Swaggart, K. A., Earley, J. U., Pytel, P., McNally, E. M. Myoferlin is required for insulin-like growth factor response and muscle growth...