Corey T McMillan

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc Converging evidence for the processing costs associated with ambiguous quantifier comprehension
    Corey T McMillan
    Frontotemporal Degeneration Center, Department of Neurology, Perelman School of Medicine, University of Pennsylvania Philadelphia, PA, USA
    Front Psychol 4:153. 2013
  2. pmc Genetic and neuroanatomic associations in sporadic frontotemporal lobar degeneration
    Corey T McMillan
    Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA Penn Frontotemporal Degeneration Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA Electronic address
    Neurobiol Aging 35:1473-82. 2014
  3. pmc White matter imaging helps dissociate tau from TDP-43 in frontotemporal lobar degeneration
    Corey T McMillan
    Department of Neurology, Perelman School of Medicine, Frontotemporal Degeneration Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Neurol Neurosurg Psychiatry 84:949-55. 2013
  4. pmc Can MRI screen for CSF biomarkers in neurodegenerative disease?
    Corey T McMillan
    Department of Neurology, University of Pennsylvania, Philadelphia, USA
    Neurology 80:132-8. 2013
  5. pmc The neural basis for establishing a focal point in pure coordination games
    Corey T McMillan
    Department of Neurology, University of Pennsylvania, Philadelphia, 19104, USA
    Soc Cogn Affect Neurosci 7:881-7. 2012
  6. pmc White matter imaging contributes to the multimodal diagnosis of frontotemporal lobar degeneration
    C T McMillan
    Department of Neurology, University of Pennsylvania, PA, USA
    Neurology 78:1761-8. 2012
  7. pmc fMRI evidence for strategic decision-making during resolution of pronoun reference
    Corey T McMillan
    University of Pennsylvania School of Medicine, Department of Neurology, Philadelphia, PA 19104, United States
    Neuropsychologia 50:674-87. 2012
  8. pmc Some is not enough: quantifier comprehension in corticobasal syndrome and behavioral variant frontotemporal dementia
    Brianna Morgan
    Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104 4283, United States
    Neuropsychologia 49:3532-41. 2011
  9. pmc Phosphorylated tau as a candidate biomarker for amyotrophic lateral sclerosis
    Murray Grossman
    Penn Frontotemporal Degeneration Center, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia
    JAMA Neurol 71:442-8. 2014
  10. pmc Sparse canonical correlation analysis relates network-level atrophy to multivariate cognitive measures in a neurodegenerative population
    Brian B Avants
    Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Neuroimage 84:698-711. 2014

Collaborators

Detail Information

Publications35

  1. pmc Converging evidence for the processing costs associated with ambiguous quantifier comprehension
    Corey T McMillan
    Frontotemporal Degeneration Center, Department of Neurology, Perelman School of Medicine, University of Pennsylvania Philadelphia, PA, USA
    Front Psychol 4:153. 2013
    ..These studies provide converging evidence that cortical regions that extend beyond peri-Sylvian cortex help support the processing costs associated with the interpretation of ambiguous doubly-quantified sentences...
  2. pmc Genetic and neuroanatomic associations in sporadic frontotemporal lobar degeneration
    Corey T McMillan
    Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA Penn Frontotemporal Degeneration Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA Electronic address
    Neurobiol Aging 35:1473-82. 2014
    ..Identified brain regions and SNPs may help provide an in vivo screen for underlying pathology in FTLD and contribute to our understanding of sporadic FTLD...
  3. pmc White matter imaging helps dissociate tau from TDP-43 in frontotemporal lobar degeneration
    Corey T McMillan
    Department of Neurology, Perelman School of Medicine, Frontotemporal Degeneration Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Neurol Neurosurg Psychiatry 84:949-55. 2013
    ..In this paper, we investigate the ability of white matter (WM) imaging to help discriminate between FTLD-TAU and FTLD-TDP during life using diffusion tensor imaging (DTI)...
  4. pmc Can MRI screen for CSF biomarkers in neurodegenerative disease?
    Corey T McMillan
    Department of Neurology, University of Pennsylvania, Philadelphia, USA
    Neurology 80:132-8. 2013
    ..In this study, we evaluate the utility of MRI as a noninvasive screening procedure for the differential diagnosis of AD and FTLD...
  5. pmc The neural basis for establishing a focal point in pure coordination games
    Corey T McMillan
    Department of Neurology, University of Pennsylvania, Philadelphia, 19104, USA
    Soc Cogn Affect Neurosci 7:881-7. 2012
    ..g. is 'John' a frequent boy's name), a hierarchical mechanism that iteratively models an opponent's likely response and a mechanism involved in social perspective taking...
  6. pmc White matter imaging contributes to the multimodal diagnosis of frontotemporal lobar degeneration
    C T McMillan
    Department of Neurology, University of Pennsylvania, PA, USA
    Neurology 78:1761-8. 2012
    ..To evaluate the distribution of white matter (WM) disease in frontotemporal lobar degeneration (FTLD) and Alzheimer disease (AD) and to evaluate the relative usefulness of WM and gray matter (GM) for distinguishing these conditions in vivo...
  7. pmc fMRI evidence for strategic decision-making during resolution of pronoun reference
    Corey T McMillan
    University of Pennsylvania School of Medicine, Department of Neurology, Philadelphia, PA 19104, United States
    Neuropsychologia 50:674-87. 2012
    ..Together, these findings are consistent with a two-component model for resolving a pronoun's reference that includes neuroanatomic regions supporting core linguistic and decision-making mechanisms...
  8. pmc Some is not enough: quantifier comprehension in corticobasal syndrome and behavioral variant frontotemporal dementia
    Brianna Morgan
    Department of Neurology, University of Pennsylvania, Philadelphia, PA 19104 4283, United States
    Neuropsychologia 49:3532-41. 2011
    ....
  9. pmc Phosphorylated tau as a candidate biomarker for amyotrophic lateral sclerosis
    Murray Grossman
    Penn Frontotemporal Degeneration Center, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia
    JAMA Neurol 71:442-8. 2014
    ..An increasingly varied clinical spectrum of cases with amyotrophic lateral sclerosis (ALS) has been identified, and objective criteria for clinical trial eligibility are necessary...
  10. pmc Sparse canonical correlation analysis relates network-level atrophy to multivariate cognitive measures in a neurodegenerative population
    Brian B Avants
    Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Neuroimage 84:698-711. 2014
    ..In conclusion, we show that multivariate techniques identify biologically-plausible brain regions supporting specific cognitive domains. The findings are identified in training data and confirmed in test data. ..
  11. pmc Grammatical comprehension deficits in non-fluent/agrammatic primary progressive aphasia
    Dorothy Charles
    Department of Neurology and Penn FTD Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Neurol Neurosurg Psychiatry 85:249-56. 2014
    ..Grammatical comprehension difficulty is an essential supporting feature of the non-fluent/agrammatic variant of primary progressive aphasia (naPPA), but well-controlled clinical measures of grammatical comprehension are unavailable...
  12. pmc Impairment of script comprehension in Lewy body spectrum disorders
    Rachel G Gross
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Brain Lang 125:330-43. 2013
    ..These findings extend prior work on script processing to patients with Lewy body spectrum disorders and highlight the potential impact of frontal/executive dysfunction on the daily lives of affected patients...
  13. pmc Comparative semantic profiles in semantic dementia and Alzheimer's disease
    David J Libon
    Department of Neurology, Drexel University, 245 North 15th Street, 7th Floor, Philadelphia, PA 19102, USA
    Brain 136:2497-509. 2013
    ..We discuss factors that may contribute to the semantic memory deficit in semantic variant primary progressive aphasia. ..
  14. pmc Comparison of cerebrospinal fluid levels of tau and Aβ 1-42 in Alzheimer disease and frontotemporal degeneration using 2 analytical platforms
    David J Irwin
    Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Institute on Aging, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA
    Arch Neurol 69:1018-25. 2012
    ..To use values of cerebrospinal fluid tau and β-amyloid obtained from 2 different analytical immunoassays to differentiate Alzheimer disease (AD) from frontotemporal lobar degeneration (FTLD)...
  15. pmc Cognitive decline and reduced survival in C9orf72 expansion frontotemporal degeneration and amyotrophic lateral sclerosis
    David J Irwin
    Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, Alzheimer s Disease Core Center, Institute on Aging, Philadelphia, Pennsylvania, USA
    J Neurol Neurosurg Psychiatry 84:163-9. 2013
    ..To clarify this issue, we compared a large C9P cohort with carefully matched non-expansion (C9N) cases with a known or highly-suspected underlying TAR DNA-binding protein 43 (TDP-43) proteinopathy...
  16. pmc Sentence processing in Lewy body spectrum disorder: the role of working memory
    Rachel G Gross
    Department of Neurology, University of Pennsylvania School of Medicine, United States
    Brain Cogn 78:85-93. 2012
    ..These findings are consistent with the hypothesis that patients with PDD and DLB have difficulty processing sentences with increased working memory demands and that this deficit is related in part to their frontal disease...
  17. pmc Myelin oligodendrocyte basic protein and prognosis in behavioral-variant frontotemporal dementia
    David J Irwin
    From the Penn Frontotemporal Degeneration Center, Department of Neurology D J I, C T M, J P, K R, E M W, M G Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Institute on Aging, Alzheimer s Disease Core Center D J I, C T M, E S, E M W, J B T, S E A, V M Y L, V M V D, J Q T, M G Penn Memory Center, Department of Neurology S E A and Brain Behavior Laboratory, Departments of Psychiatry, Perelman School of Medicine S E A, University of Pennsylvania, Philadelphia
    Neurology 83:502-9. 2014
    ..To determine the prognostic utility of tauopathy-associated single nucleotide polymorphisms (SNPs) in sporadic behavioral-variant frontotemporal dementia (bvFTD)...
  18. pmc Self-appraisal in behavioural variant frontotemporal degeneration
    Lauren Massimo
    Department of Neurology, University of Pennsylvania, 3400 Spruce Street, Gates Building, Philadelphia, PA 19104, USA
    J Neurol Neurosurg Psychiatry 84:148-53. 2013
    ..We examined whether a domain-specific versus multi-domain model best explains degraded self-appraisal in bvFTD...
  19. pmc Category-specific semantic memory: converging evidence from bold fMRI and Alzheimer's disease
    Murray Grossman
    Frontotemporal Degeneration Center, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 4283, USA
    Neuroimage 68:263-74. 2013
    ....
  20. ncbi Quantifier comprehension in corticobasal degeneration
    Corey T McMillan
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Brain Cogn 62:250-60. 2006
    ..29; p<.001]. An important implication of these findings is that the meaning of generalized quantifiers appears to involve two dissociable components, number knowledge and working memory, which are supported by distinct brain regions...
  21. doi Deficits in sentence expression in amyotrophic lateral sclerosis
    Sharon Ash
    Department of Neurology and the Penn Frontotemporal Degeneration Center, Philadelphia, USA
    Amyotroph Lateral Scler Frontotemporal Degener 16:31-9. 2015
    ..They demonstrate a deficit in grammatical expression that is independent of their motor disorder. Impaired grammatical expression is related to disease in a network of brain regions associated with syntactic processing. ..
  22. pmc Narrative discourse deficits in amyotrophic lateral sclerosis
    Sharon Ash
    From the Department of Neurology and the Penn Frontotemporal Degeneration Center S A, A M, C O, C T M, A B, D J I, L M, L E, M G, and Center for Neurodegenerative Disease Research D J I, Perelman School of Medicine, University of Pennsylvania, Philadelphia
    Neurology 83:520-8. 2014
    ..We examined narrative discourse in amyotrophic lateral sclerosis (ALS) to assess the role of executive functioning in support of language and the neuroanatomical basis for such support...
  23. pmc Impaired information integration contributes to communication difficulty in corticobasal syndrome
    Rachel G Gross
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 4283, USA
    Cogn Behav Neurol 23:1-7. 2010
    ..To investigate the cognitive and neural correlates of discourse impairment in corticobasal syndrome (CBS)...
  24. doi Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine
    David J Irwin
    Department of Pathology and Laboratory Medicine, Center for Neurodegenerative Disease Research, Institute on Ageing, University of Pennsylvania School of Medicine, HUP Maloney 3rd Floor, 36th and Spruce Streets, Philadelphia, PA, 19104 4283, USA
    Acta Neuropathol 129:469-91. 2015
    ....
  25. doi Impaired cognitive flexibility in amyotrophic lateral sclerosis
    Jessica Evans
    Department of Psychology, Villanova University, Villanova, Pennsylvania Department of Neurology and Penn Frontotemporal Degeneration Center, University of Pennsylvania, Philadelphia, Pennsylvania
    Cogn Behav Neurol 28:17-26. 2015
    ..Our objective was to assess executive function in patients with ALS using a simple, untimed measure with minimal motor demands, and to relate performance to structural disease...
  26. pmc ALS-Plus syndrome: non-pyramidal features in a large ALS cohort
    Leo McCluskey
    Department of Neurology, University of Pennsylvania, United States
    J Neurol Sci 345:118-24. 2014
    ..We investigated ALS-Plus syndrome, an understudied group of patients with clinical features extending beyond pyramidal and neuromuscular systems with or without cognitive/behavioral deficits...
  27. pmc Relating brain anatomy and cognitive ability using a multivariate multimodal framework
    Philip A Cook
    Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA Electronic address
    Neuroimage 99:477-86. 2014
    ..We conclude that clustering the data with eigenanatomy before performing linear regression is a promising tool for multimodal data analysis. ..
  28. pmc Difficulty processing temporary syntactic ambiguities in Lewy body spectrum disorder
    Murray Grossman
    Department of Neurology, University of Pennsylvania School of Medicine, United States
    Brain Lang 120:52-60. 2012
    ..These findings emphasize the role of prefrontal disease in the executive limitations that interfere with processing ambiguous sentences in LBSD...
  29. doi Getting on the same page: the neural basis for social coordination deficits in behavioral variant frontotemporal degeneration
    Meghan L Healey
    University of Pennsylvania Perelman School of Medicine, Penn Department of Neurology and Frontotemporal Degeneration Center, Philadelphia, 19104 PA, USA University of Pennsylvania, Neuroscience Graduate Group, Philadelphia, 19104 PA, USA Electronic address
    Neuropsychologia 69:56-66. 2015
    ..Our findings suggest an important role for non-language brain areas that belong to a large-scale neurocognitive network for social coordination. ..
  30. pmc The power of neuroimaging biomarkers for screening frontotemporal dementia
    Corey T McMillan
    Department of Neurology, Penn Frontotemporal Degeneration Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
    Hum Brain Mapp 35:4827-40. 2014
    ....
  31. pmc Hypermethylation of repeat expanded C9orf72 is a clinical and molecular disease modifier
    Jenny Russ
    Translational Neuropathology Research Laboratory, Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, 605B Stellar Chance Laboratories, 422 Curie Blvd, Philadelphia, PA, 19104, USA
    Acta Neuropathol 129:39-52. 2015
    ..These results support the hypothesis that expression of the hexanucleotide repeat expansion is associated with a toxic gain of function...
  32. pmc White matter disease contributes to apathy and disinhibition in behavioral variant frontotemporal dementia
    John P Powers
    Penn Frontotemporal Degeneration Center, Department of Neurology Penn Image Computing and Science Laboratory, Department of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania Centre for Medical Image Computing, Department of Computer Science, University College London, London, United Kingdom
    Cogn Behav Neurol 27:206-14. 2014
    ..To relate changes in fractional anisotropy associated with behavioral variant frontotemporal dementia to measures of apathy and disinhibition...
  33. pmc Eigenanatomy improves detection power for longitudinal cortical change
    Brian Avants
    Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Med Image Comput Comput Assist Interv 15:206-13. 2012
    ..These regions improve our ability to quantify biologically plausible rates of cortical change in two distinct forms of neurodegeneration. We detail the algorithm and show experimental evidence of its efficacy...
  34. ncbi Neural basis for generalized quantifier comprehension
    Corey T McMillan
    Department of Neurology, University of Pennsylvania Medical Center, Philadelphia, PA 19104 4283, USA
    Neuropsychologia 43:1729-37. 2005
    ..Our findings are consistent with a large-scale neural network centered in frontal and parietal cortex that supports comprehension of generalized quantifiers...