David D McManus

Summary

Affiliation: University of Massachusetts Medical School
Country: USA

Publications

  1. doi request reprint Reliability of Predicting Early Hospital Readmission After Discharge for an Acute Coronary Syndrome Using Claims-Based Data
    David D McManus
    Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts Department of Medicine, Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, Massachusetts Electronic address
    Am J Cardiol 117:501-7. 2016
  2. pmc Plasma microRNAs are associated with atrial fibrillation and change after catheter ablation (the miRhythm study)
    David D McManus
    Cardiology Division, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts National Heart Lung and Blood Institute s and Boston University s Framingham Heart Study, Framingham, Massachusetts Epidemiology Division, Department of Quantitative Health Sciences, University of Massachusetts Medical School Worcester, Massachusetts Electronic address
    Heart Rhythm 12:3-10. 2015
  3. pmc Inadvertent lead placement in the left ventricle: a case report and brief review
    David D McManus
    Electrophysiology Section, Division of Cardiology, Department of Medicine, University of Massachusetts Medical Center, Worcester, MA 01655
    Indian Pacing Electrophysiol J 9:224-8. 2009
  4. pmc Relations between circulating microRNAs and atrial fibrillation: data from the Framingham Offspring Study
    David D McManus
    National Heart Lung and Blood Institute s and Boston University s Framingham Heart Study, Framingham, Massachusetts Cardiology Division, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts Epidemiology Division, Department of Quantitative Health Sciences, University of Massachusetts Medical School Worcester, Massachusetts Electronic address
    Heart Rhythm 11:663-9. 2014
  5. pmc Atrial fibrillation and outcomes in heart failure with preserved versus reduced left ventricular ejection fraction
    David D McManus
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical Center, Worcester, MA 01655, USA
    J Am Heart Assoc 2:e005694. 2013
  6. pmc A novel application for the detection of an irregular pulse using an iPhone 4S in patients with atrial fibrillation
    David D McManus
    Cardiac Electrophysiology Section, Cardiovascular Medicine Division, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Heart Rhythm 10:315-9. 2013
  7. pmc Atrial fibrillation and heart failure parallels: lessons for atrial fibrillation prevention
    David D McManus
    Departments of Medicine and Quantitative Health Sciences, University of Massachusetts Medical Center, Worcester, MA 01655, USA
    Crit Pathw Cardiol 10:46-51. 2011
  8. pmc Galectin 3 and incident atrial fibrillation in the community
    Jennifer E Ho
    Boston University and the National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA Section of Cardiovascular Medicine, Department of Medicine, Boston University, Boston, MA Electronic address
    Am Heart J 167:729-34.e1. 2014
  9. pmc Recent trends in the incidence, treatment, and prognosis of patients with heart failure and atrial fibrillation (the Worcester Heart Failure Study)
    David D McManus
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA
    Am J Cardiol 111:1460-5. 2013
  10. pmc Risk assessment for incident heart failure in individuals with atrial fibrillation
    Renate B Schnabel
    NHLBI s and Boston University s Framingham Heart Study, Framingham, MA, USA
    Eur J Heart Fail 15:843-9. 2013

Detail Information

Publications62

  1. doi request reprint Reliability of Predicting Early Hospital Readmission After Discharge for an Acute Coronary Syndrome Using Claims-Based Data
    David D McManus
    Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts Department of Medicine, Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, Massachusetts Electronic address
    Am J Cardiol 117:501-7. 2016
    ..Incorporating additional factors into risk-adjusted readmission models may improve their accuracy and validity for use as indicators of hospital quality. ..
  2. pmc Plasma microRNAs are associated with atrial fibrillation and change after catheter ablation (the miRhythm study)
    David D McManus
    Cardiology Division, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts National Heart Lung and Blood Institute s and Boston University s Framingham Heart Study, Framingham, Massachusetts Epidemiology Division, Department of Quantitative Health Sciences, University of Massachusetts Medical School Worcester, Massachusetts Electronic address
    Heart Rhythm 12:3-10. 2015
    ..MicroRNAs (miRNAs) are associated with cardiovascular disease and control gene expression and are detectable in the circulation...
  3. pmc Inadvertent lead placement in the left ventricle: a case report and brief review
    David D McManus
    Electrophysiology Section, Division of Cardiology, Department of Medicine, University of Massachusetts Medical Center, Worcester, MA 01655
    Indian Pacing Electrophysiol J 9:224-8. 2009
    ..In this report, we describe a case of inadvertent LV lead placement and briefly review the contemporary literature...
  4. pmc Relations between circulating microRNAs and atrial fibrillation: data from the Framingham Offspring Study
    David D McManus
    National Heart Lung and Blood Institute s and Boston University s Framingham Heart Study, Framingham, Massachusetts Cardiology Division, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts Epidemiology Division, Department of Quantitative Health Sciences, University of Massachusetts Medical School Worcester, Massachusetts Electronic address
    Heart Rhythm 11:663-9. 2014
    ..MicroRNA (miRNA) expression in atrial tissue has been implicated in pathologic susceptibility to atrial fibrillation (AF). Nevertheless, data on how circulating levels relate to AF are limited...
  5. pmc Atrial fibrillation and outcomes in heart failure with preserved versus reduced left ventricular ejection fraction
    David D McManus
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical Center, Worcester, MA 01655, USA
    J Am Heart Assoc 2:e005694. 2013
    ..We examined how AF has impacts on adverse outcomes in HF-PEF versus HF-REF within a large, contemporary cohort...
  6. pmc A novel application for the detection of an irregular pulse using an iPhone 4S in patients with atrial fibrillation
    David D McManus
    Cardiac Electrophysiology Section, Cardiovascular Medicine Division, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Heart Rhythm 10:315-9. 2013
    ..Timely detection of AF can be challenging using traditional diagnostic tools. Smartphone use is increasing and may provide an inexpensive and user-friendly means to diagnoseAF...
  7. pmc Atrial fibrillation and heart failure parallels: lessons for atrial fibrillation prevention
    David D McManus
    Departments of Medicine and Quantitative Health Sciences, University of Massachusetts Medical Center, Worcester, MA 01655, USA
    Crit Pathw Cardiol 10:46-51. 2011
    ..By reviewing some of the mechanistic parallels between AF and HF, we hope to emphasize the connection between established cardiovascular risk factors, cardiac remodeling and AF, with a view to promote strategies for AF prevention...
  8. pmc Galectin 3 and incident atrial fibrillation in the community
    Jennifer E Ho
    Boston University and the National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA Section of Cardiovascular Medicine, Department of Medicine, Boston University, Boston, MA Electronic address
    Am Heart J 167:729-34.e1. 2014
    ..The same mechanisms that lead to cardiac fibrosis in heart failure may influence development of atrial fibrosis and atrial fibrillation (AF). We examined the association of Gal-3 and incident AF in the community...
  9. pmc Recent trends in the incidence, treatment, and prognosis of patients with heart failure and atrial fibrillation (the Worcester Heart Failure Study)
    David D McManus
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA
    Am J Cardiol 111:1460-5. 2013
    ..Despite improving trends in survival, patients with ADHF and AF are at increased risk of in-hospital and postdischarge mortality...
  10. pmc Risk assessment for incident heart failure in individuals with atrial fibrillation
    Renate B Schnabel
    NHLBI s and Boston University s Framingham Heart Study, Framingham, MA, USA
    Eur J Heart Fail 15:843-9. 2013
    ..Risk factors that predict HF in individuals with AF in the community are not well established...
  11. pmc Decade-long trends in the magnitude, treatment, and outcomes of patients aged 30 to 54 years hospitalized with ST-segment elevation and non-ST-segment elevation myocardial infarction
    Mayra Tisminetzky
    Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts
    Am J Cardiol 113:1606-10. 2014
    ..Patients with STEMI and NSTEMI had similar in-hospital outcomes and long-term survival. Trends in these and other important outcomes warrant continued monitoring...
  12. pmc 30-year trends in patient characteristics, treatment practices, and long-term outcomes of adults aged 35 to 54 years hospitalized with acute myocardial infarction
    Mayra Tisminetzky
    Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts
    Am J Cardiol 113:1137-41. 2014
    ..The present results provide insights into the changing characteristics, management, and improving long-term outcomes of relatively young patients hospitalized with AMI. ..
  13. pmc Contemporary prevalence and correlates of incident heart failure with preserved ejection fraction
    Jerry H Gurwitz
    Meyers Primary Care Institute and Fallon Community Health Plan, Worcester, MA 01605, USA
    Am J Med 126:393-400. 2013
    ....
  14. pmc Management and outcomes of renal disease and acute myocardial infarction
    Paul A Santolucito
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA
    Am J Med 123:847-55. 2010
    ....
  15. pmc Comparison of medication practices in patients with heart failure and preserved versus those with reduced ejection fraction (from the Cardiovascular Research Network [CVRN])
    Robert J Goldberg
    Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA
    Am J Cardiol 111:1324-9. 2013
    ..In conclusion, the present results from a large, population-based sample suggest considerable variation in the previous and new use of different cardiac medication classes of drugs in patients with HF-PEF versus HF-REF...
  16. doi request reprint Characteristics of contemporary patients discharged from the hospital after an acute coronary syndrome
    Robert J Goldberg
    Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester Electronic address
    Am J Med 128:1087-93. 2015
    ..We describe these factors in a cohort of patients recruited from 6 hospitals in Massachusetts and Georgia after an acute coronary syndrome...
  17. pmc Transitions, Risks, and Actions in Coronary Events--Center for Outcomes Research and Education (TRACE-CORE): design and rationale
    Molly E Waring
    Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Circ Cardiovasc Qual Outcomes 5:e44-50. 2012
    ....
  18. pmc The complex relationship of race to outcomes in heart failure with preserved ejection fraction
    Jerry H Gurwitz
    Meyers Primary Care Institute, University of Massachusetts Medical School, Fallon Community Health Plan, and Reliant Medical Group, Worcester, Mass Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Mass Department of Medicine, University of Massachusetts Medical School, Worcester, Mass Electronic address
    Am J Med 128:591-600. 2015
    ..We assessed how clinical characteristics and outcomes vary across racial groups (whites, blacks, and Asians) in adults with heart failure with preserved ejection fraction...
  19. pmc Relationship among circulating inflammatory proteins, platelet gene expression, and cardiovascular risk
    David D McManus
    From the National Heart Lung and Blood Institute s and Boston University s Framingham Heart Study, Framingham, MA D D M, K T, M G L, J E F Cardiology Division, Department of Medicine D D M, L M B, K T, J F K, J E F and Epidemiology Division, Department of Quantitative Health Sciences D D M, E M, University of Massachusetts Medical School, Worcester, MA Section of Cardiovascular Medicine, Department of Medicine E J B and Department of Mathematics and Statistics M G L, Boston University, Boston, MA Preventive Medicine Section, Department of Medicine, Boston University School of Medicine, Boston, MA E J B and Department of Epidemiology E J B and Department of Biostatistics M G L, Boston University School of Public Health, Boston, MA
    Arterioscler Thromb Vasc Biol 33:2666-73. 2013
    ....
  20. doi request reprint Outcomes from patients with multi-vessel disease following primary PCI: staged PCI imparts very low mortality
    Kurt G Barringhaus
    University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Catheter Cardiovasc Interv 77:617-22. 2011
    ..CABG and PCI are effective means for revascularization of patients with multi-vessel coronary artery disease, but previous studies have not focused on treatment of patients that first undergo primary PCI...
  21. pmc Patterns of comorbidity in older adults with heart failure: the Cardiovascular Research Network PRESERVE study
    Jane S Saczynski
    Meyers Primary Care Institute and Fallon Community Health Plan, Worcester, Massachusetts 01605, USA
    J Am Geriatr Soc 61:26-33. 2013
    ..To examine whether the total burden of comorbidity and pattern of co-occurring conditions varies in individuals with heart failure (HF) with preserved left ventricular ejection fraction (LVEF) (HF-P) or HF with reduced LVEF (HF-R)...
  22. pmc Trends in atrial fibrillation in patients hospitalized with an acute coronary syndrome
    David D McManus
    Department of Medicine, University of Massachusetts Medical School, Worcester Division of Epidemiology, Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Am J Med 125:1076-84. 2012
    ..Data are needed on recent trends in the magnitude, clinical features, treatment, and prognostic impact of preexisting and new-onset atrial fibrillation in patients hospitalized with an acute coronary syndrome...
  23. doi request reprint Perceiving one's heart condition to be cured following hospitalization for acute coronary syndromes: Implications for patient-provider communication
    Molly E Waring
    Department of Quantitative Health Sciences, University of Massachusetts Medical School, 368 Plantation Street, Worcester, MA 01605, USA Electronic address
    Patient Educ Couns 99:455-61. 2016
    ..We examined the proportion of patients perceiving their heart condition to be cured following hospitalization for ACS and identified characteristics associated with these perceptions...
  24. pmc Decade-long trends in the characteristics, management and hospital outcomes of diabetic patients with ST-segment elevation myocardial infarction
    Mayra Tisminetzky
    Division of Epidemiology of Chronic Diseases and Vulnerable Populations, Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA
    Diab Vasc Dis Res 11:182-9. 2014
    ..Our objectives were to describe recent trends in the characteristics and in-hospital outcomes in diabetic as compared with non-diabetic patients hospitalized with ST-segment elevation myocardial infarction (STEMI)...
  25. pmc Speckle echocardiographic left atrial strain and stiffness index as predictors of maintenance of sinus rhythm after cardioversion for atrial fibrillation: a prospective study
    Amir Y Shaikh
    Department of Internal Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Cardiovasc Ultrasound 10:48. 2012
    ..Our goal was to determine if strain measures [peak systolic longitudinal strain (LAS) and stiffness index (LASt)] changed after cardioversion (CV); and their relation to AF recurrence...
  26. pmc 30-year trends in heart failure in patients hospitalized with acute myocardial infarction
    David D McManus
    Department of Medicine, University of Massachusetts Medical School, Worcester, USA
    Am J Cardiol 107:353-9. 2011
    ..In conclusion, HF remains a common and frequently fatal complication of AMI to which increased surveillance and treatment efforts should be directed...
  27. pmc Thirty-year (1975 to 2005) trends in the incidence rates, clinical features, treatment practices, and short-term outcomes of patients <55 years of age hospitalized with an initial acute myocardial infarction
    David D McManus
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Am J Cardiol 108:477-82. 2011
    ..Decreasing odds of developing or dying from an initial AMI during the 30 years under study likely reflect increased primary and secondary prevention and treatment efforts...
  28. pmc Long-term outcomes of secondary atrial fibrillation in the community: the Framingham Heart Study
    Steven A Lubitz
    From Cardiovascular Research Center S A L, P T E and Cardiac Arrhythmia Service S A L, P T E, Massachusetts General Hospital, Boston Boston University and National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA X Y, J W M, D L, R S V, M G L, E J B Department of Cardiology, University of Groningen, University Medical Center Groningen, The Netherlands M R Department of General and Interventional Cardiology, University Medical Center Hamburg Eppendorf, Hamburg, Germany R B S Pulmonary Center and Section of Pulmonary and Critical Care Medicine A J W, Section of Cardiovascular Medicine J W M, R S V, E J B, and Section of Preventive Medicine R S V, E J B, Department of Medicine, Boston University School of Medicine, MA Department of Medicine, Boston University Medical Center, MA F R Departments of Medicine and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester D D M Sutter Medical Group, Sacramento, CA T M T Population Sciences Branch, National Heart, Lung, and Blood Institute, Bethesda, Guy's Campus
    Circulation 131:1648-55. 2015
    ..However, knowledge of long-term AF outcomes after diagnosis during a secondary precipitant is limited...
  29. pmc Cardiometabolic correlates and heritability of fetuin-A, retinol-binding protein 4, and fatty-acid binding protein 4 in the Framingham Heart Study
    Bernhard M Kaess
    National Heart, Blood, and Lung Institute s Framingham Heart Study, Framingham, MA 01702, USA
    J Clin Endocrinol Metab 97:E1943-7. 2012
    ..Fetuin-A, retinol-binding protein 4 (RBP4), and fatty-acid binding protein 4 (FABP4) are novel biomarkers that may link adiposity to insulin resistance and the metabolic syndrome (MetSyn)...
  30. pmc Whole blood gene expression and atrial fibrillation: the Framingham Heart Study
    Honghuang Lin
    Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America National Heart Lung and Blood Institute s and Boston University s Framingham Heart Study, Framingham, Massachusetts, United States of America
    PLoS ONE 9:e96794. 2014
    ..Atrial fibrillation (AF) involves substantial electrophysiological, structural and contractile remodeling. We hypothesize that characterizing gene expression might uncover important pathways related to AF...
  31. pmc Improved survival after heart failure: a community-based perspective
    Samuel W Joffe
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Am Heart Assoc 2:e000053. 2013
    ..A secondary objective was to examine patient characteristics associated with decreased long-term survival...
  32. doi request reprint Relation of Atrial Fibrillation in Acute Myocardial Infarction to In-Hospital Complications and Early Hospital Readmission
    Amartya Kundu
    Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts
    Am J Cardiol 117:1213-8. 2016
    ..3% vs 5.1%). In conclusion, new-onset AF after AMI is strongly related to in-hospital complications of AMI and higher short-term readmission rates. ..
  33. pmc Recent trends in the incidence, treatment, and outcomes of patients with STEMI and NSTEMI
    David D McManus
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Am J Med 124:40-7. 2011
    ....
  34. doi request reprint Atrial Fibrillation Begets Heart Failure and Vice Versa: Temporal Associations and Differences in Preserved Versus Reduced Ejection Fraction
    Rajalakshmi Santhanakrishnan
    From Cardiovascular Medicine Section, Department of Medicine R S, J W M, R S V, E J B and Section of Preventive Medicine and Epidemiology R S V, Boston University School of Medicine, MA Data Coordinating Center N W and Department of Epidemiology E J B, Boston University School of Public Health, MA Department of Mathematics and Statistics, Boston University, MA M G L National Heart, Lung, and Blood Institute s and Boston University s Framingham Heart Study, MA M G L, J W M, S C, R S V, D L, E J B, J E H Cardiology Division, Department of Medicine, University of Massachusetts Medical School, Boston D D M, E J B Cardiology Division S A L, P T E, J E H and Cardiovascular Research Center S A L, P T E, J E H, Massachusetts General Hospital, Harvard Medical School, Boston Program in Medical Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge S A L, P T E Division of Cardiology, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, USA
    Circulation 133:484-92. 2016
    ..The association of AF with HF subtypes has not been well described. We sought to examine differences in the temporal association of AF and HF with preserved versus reduced ejection fraction...
  35. doi request reprint PULSE-SMART: Pulse-Based Arrhythmia Discrimination Using a Novel Smartphone Application
    David D McManus
    Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    J Cardiovasc Electrophysiol 27:51-7. 2016
    ..Atrial fibrillation (AF) is a common and dangerous rhythm abnormality. Smartphones are increasingly used for mobile health applications by older patients at risk for AF and may be useful for AF screening...
  36. pmc Thirty-day Hospital Readmissions in Patients with Non-ST-segment Elevation Acute Myocardial Infarction
    Mayra Tisminetzky
    Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester
    Am J Med 128:760-5. 2015
    ..This observational study describes decade-long trends (1999-2009) in the magnitude and characteristics of patients readmitted to the hospital within 30 days of hospitalization for an incident (initial) episode of NSTEMI...
  37. doi request reprint Cognitive status in patients hospitalized with acute decompensated heart failure
    Seth N Levin
    Department of Medicine, University of Massachusetts Medical School UMMS, Worcester, MA
    Am Heart J 168:917-23. 2014
    ..We investigated the prevalence of impairment in 3 cognitive domains in patients hospitalized with acute decompensated heart failure (ADHF) and the associations of impairment with demographic and clinical characteristics...
  38. pmc Characteristics, treatment practices, and in-hospital outcomes of older adults hospitalized with acute myocardial infarction
    Han Yang Chen
    Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts
    J Am Geriatr Soc 62:1451-9. 2014
    ....
  39. pmc Long-term survival for patients with acute decompensated heart failure according to ejection fraction findings
    Andrew H Coles
    Program in Gene Function and Expression, University of Massachusetts Medical School, Worcester, Massachusetts
    Am J Cardiol 114:862-8. 2014
    ..In conclusion, although improvements in 1-year postdischarge survival were observed for patients in each of the 3 EF groups examined to varying degrees, the postdischarge prognosis of all patients with ADHF remains guarded...
  40. doi request reprint Atrial fibrillation detection using a smart phone
    Jinseok Lee
    WPI, Worcester, MA 01609, USA
    Conf Proc IEEE Eng Med Biol Soc 2012:1177-80. 2012
    ..Using this criterion, we achieved an accuracy of 100% for both detecting the presence of either AF or NSR...
  41. pmc Delayed hospital presentation in acute decompensated heart failure: clinical and patient reported factors
    Chad Darling
    Department of Emergency Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Heart Lung 42:281-6. 2013
    ..Prior studies have examined the reasons why such delays may occur, but additional studies are needed to identify modifiable factors contributing to these delays...
  42. pmc Incidence, prognosis, and factors associated with cardiac arrest in patients hospitalized with acute coronary syndromes (the Global Registry of Acute Coronary Events Registry)
    David D McManus
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Coron Artery Dis 23:105-12. 2012
    ..The objectives of this multinational study were to characterize trends in the magnitude of in-hospital VF-CA complicating an ACS and to describe its impact over time on hospital prognosis...
  43. pmc Increase in the proportion of patients hospitalized with acute myocardial infarction with do-not-resuscitate orders already in place between 2001 and 2007: a nonconcurrent prospective study
    Jane S Saczynski
    Department of Medicine, University of Massachusetts Medical School, Worcester Meyers Primary Care Institute, Worcester Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester
    Clin Epidemiol 4:267-74. 2012
    ..Here, we describe the use and timing of do-not-resuscitate (DNR) orders in patients hospitalized with acute myocardial infarction (AMI)...
  44. doi request reprint Decade-Long Trends (2001-2011) in the Incidence and Hospital Death Rates Associated with the In-Hospital Development of Cardiogenic Shock after Acute Myocardial Infarction
    Robert J Goldberg
    From the Departments of Quantitative Health Sciences R J G, R C P M J Y, D L, and Medicine D D M, J M G, University of Massachusetts Medical School, Worcester
    Circ Cardiovasc Qual Outcomes 9:117-25. 2016
    ....
  45. pmc Targeted sequencing in candidate genes for atrial fibrillation: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study
    Honghuang Lin
    Department of Medicine, Boston University School of Medicine, Boston, Massachusetts The NHLBI s Framingham Heart Study, Framingham, Massachusetts Electronic address
    Heart Rhythm 11:452-7. 2014
    ..Genome-wide association studies (GWAS) have identified common genetic variants that predispose to atrial fibrillation (AF). It is unclear whether rare and low-frequency variants in genes implicated by such GWAS confer additional risk of AF...
  46. doi request reprint Elevated serum glucose levels and survival after acute heart failure: a population-based perspective
    Benjamin K I Helfand
    Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA
    Diab Vasc Dis Res 12:119-25. 2015
    ..Our objectives were to examine differences in these endpoints in patients hospitalized with ADHF...
  47. pmc Meta-analysis of increased heart rate and blood pressure associated with CNS stimulant treatment of ADHD in adults
    Eric Mick
    Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA
    Eur Neuropsychopharmacol 23:534-41. 2013
    ....
  48. doi request reprint Management strategies in atrial fibrillation in patients with heart failure
    Amir Y Shaikh
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Cardiol Rev 20:288-96. 2012
    ..This article focuses on reviewing contemporary data as it pertains to AF management in patients with HF and provides insight into investigational therapies currently under development...
  49. pmc Trends in the medical management of patients with heart failure
    Samuel W Joffe
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA
    J Clin Med Res 5:194-204. 2013
    ....
  50. doi request reprint Addition of B-Type Natriuretic Peptide to Existing Clinical Risk Scores Enhances Identification of Patients at Risk for Atrial Fibrillation Recurrence After Pulmonary Vein Isolation
    Amir Y Shaikh
    From the Department of Medicine, University of Massachusetts Medical School, Worcester, MA Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA Department of Medicine, Rutgers New Jersey Medical School, Newark, NJ Division of Cardiology and Electrophysiology, University of Massachusetts Medical School, Worcester, MA and Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA
    Crit Pathw Cardiol 14:157-65. 2015
    ..We sought to evaluate the incremental benefit of adding preoperative BNP to existing risk scores for predicting AF recurrence during the 6 months after PVI...
  51. pmc Greater knowledge and appreciation of commonly-used research study designs
    Robert J Goldberg
    Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Am J Med 126:169.e1-8. 2013
    ..It is hoped that careful attention to the concerns we have raised will lead to the design and conduct of high-quality research projects and their write-up...
  52. pmc Gene expression and genetic variation in human atria
    Honghuang Lin
    National Heart Lung and Blood Institute s and Boston University s Framingham Heart Study, Framingham, Massachusetts Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts Electronic address
    Heart Rhythm 11:266-71. 2014
    ..The human left and right atria have different susceptibilities to develop atrial fibrillation (AF). However, the molecular events related to structural and functional changes that enhance AF susceptibility are still poorly understood...
  53. pmc Relations of circulating resistin and adiponectin and cardiac structure and function: the Framingham Offspring Study
    David D McManus
    National Heart, Lung, and Blood Institute s and Boston University s Framingham Heart Study, Framingham, Massachusetts, USA
    Obesity (Silver Spring) 20:1882-6. 2012
    ..In conclusion, these associations identify potential mechanisms by which excess adiposity may mediate adverse cardiac remodeling and HF risk...
  54. pmc Commonly used data-collection approaches in clinical research
    Jane S Saczynski
    Department of Medicine, University of Massachusetts Medical School, Worcester Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester
    Am J Med 126:946-50. 2013
    ..We hope that the points raised in this overview will lead to the collection of rich and high-quality data in observational studies and randomized controlled trials. ..
  55. pmc Prognostic value of left ventricular end-systolic volume index as a predictor of heart failure hospitalization in stable coronary artery disease: data from the Heart and Soul Study
    David D McManus
    Division of Cardiology, Department of Medicine, University of California, San Francisco, California 94143, USA
    J Am Soc Echocardiogr 22:190-7. 2009
    ..The prognostic value of ESVI and its merit relative to other markers of LV remodeling in patients with coronary heart disease are unknown...
  56. doi request reprint Photoplethysmograph signal reconstruction based on a novel hybrid motion artifact detection-reduction approach. Part I: Motion and noise artifact detection
    Jo Woon Chong
    Department of Biomedical Engineering, Worcester Polytechnic Institute, Worcester, MA, 01609 2280, USA
    Ann Biomed Eng 42:2238-50. 2014
    ..Finally, our MNA detection algorithm is real-time realizable as the computational speed on the 7-s PPG data segment was found to be only 7 ms with a Matlab code. ..
  57. doi request reprint Decision-making under uncertainty in advanced heart failure
    Theo E Meyer
    Department of Medicine, Division of Cardiology, University of Massachusetts Medical Center, 55 Lake Ave North, Worcester, MA, 01655, USA
    Curr Heart Fail Rep 11:188-96. 2014
    ..Secondly, a tool is provided that promulgates a structured approach to key data elements in an attempt to create a sound platform for decision-making. ..
  58. pmc Relation of kidney function and albuminuria with atrial fibrillation (from the Heart and Soul Study)
    David D McManus
    Section of Cardiac Electrophysiology, Division of Cardiology, Department of Medicine, University of Massachusetts, Worcester, Massachusetts, USA
    Am J Cardiol 104:1551-5. 2009
    ..36, 95% CI 1.45 to 13.05) or eGFR(Cr) (OR 4.61, 95% CI 1.56 to 13.66). In conclusion, among outpatients with coronary artery disease, lower eGFR(cys) and higher ACR were associated with prevalent AF, independent of each other...
  59. pmc Multiple cardiovascular comorbidities and acute myocardial infarction: temporal trends (1990-2007) and impact on death rates at 30 days and 1 year
    David D McManus
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA
    Clin Epidemiol 4:115-23. 2012
    ....
  60. doi request reprint Automatic motion and noise artifact detection in Holter ECG data using empirical mode decomposition and statistical approaches
    Jinseok Lee
    Department of Biomedical Engineering, Worcester Polytechnic Institute, MA 01609, USA
    IEEE Trans Biomed Eng 59:1499-506. 2012
    ..48%-74.62%) on six subjects diagnosed with AF. Finally, the computation time was less than 0.2 s using a MATLAB code, indicating that real-time application of the algorithms is possible for Holter monitoring...
  61. doi request reprint Atrial fibrillation detection using an iPhone 4S
    Jinseok Lee
    Department of Biomedical Engineering, Worcester Polytechnic Institute, MA 01609, USA
    IEEE Trans Biomed Eng 60:203-6. 2013
    ..It should be recognized that for clinical applications, the most relevant objective is to detect the presence of AF in the data. Using this criterion, we achieved an accuracy of 100% for both the MIT-BIH AF and iPhone 4S databases...
  62. doi request reprint MicroRNAs in platelet function and cardiovascular disease
    David D McManus
    Cardiology Division, Department of Medicine, University of Massachusetts Medical School, AS7 1051, 368 Plantation Street, Worcester, MA 01605 4319, USA
    Nat Rev Cardiol 12:711-7. 2015
    ..In addition, evidence suggests that platelet-derived miRNAs might have important roles as biomarkers of cardiovascular disease susceptibility, prognosis, or treatment...