JAMES LEWIS MCMANAMAN

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. pmc Dynamics and molecular determinants of cytoplasmic lipid droplet clustering and dispersion
    David J Orlicky
    Department of Pathology, University of Colorado School of Medicine, Aurora, Colorado, United States of America
    PLoS ONE 8:e66837. 2013
  2. pmc Dynamic regulation of hepatic lipid droplet properties by diet
    Amanda E Crunk
    Graduate Program of Molecular Biology, University of Colorado School of Medicine, Aurora, Colorado, United States of America
    PLoS ONE 8:e67631. 2013
  3. doi request reprint Lipid transport in the lactating mammary gland
    James L McManaman
    Division of Basic Reproductive Sciences, University of Colorado School of Medicine, Mail Stop 8613, 12700 E 19th Ave, Aurora, CO, 80045, USA
    J Mammary Gland Biol Neoplasia 19:35-42. 2014
  4. pmc Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease
    James L McManaman
    Division of Basic Reproductive Sciences, University of Colorado School of Medicine, Aurora, CO, USA
    J Lipid Res 54:1346-59. 2013
  5. pmc Characterization of the Six1 homeobox gene in normal mammary gland morphogenesis
    Ricardo D Coletta
    Department of Obstetrics and Gynecology, University of Colorado Denver, Anschutz Medical Campus, 12800 E, 19th Ave, Aurora, CO 80045, USA
    BMC Dev Biol 10:4. 2010

Research Grants

  1. MECHANISMS OF MILK LIPID SECRETION
    JAMES MCMANAMAN; Fiscal Year: 2004
  2. MECHANISMS OF MILK LIPID SECRETION
    JAMES MCMANAMAN; Fiscal Year: 2006
  3. MECHANISMS OF MILK LIPID SECRETION
    JAMES MCMANAMAN; Fiscal Year: 2007
  4. MECHANISMS OF MILK LIPID SECRETION
    JAMES MCMANAMAN; Fiscal Year: 2005
  5. MECHANISMS OF MILK LIPID SECRETION
    JAMES MCMANAMAN; Fiscal Year: 2009
  6. MECHANISMS OF MILK LIPID SECRETION
    JAMES LEWIS MCMANAMAN; Fiscal Year: 2010

Collaborators

  • Paul S MacLean
  • David J Orlicky
  • Amanda E Crunk
  • Jenifer Monks
  • Ricardo D Coletta
  • Matthew Jackman
  • Adrianne L Stefanski
  • Aya Murakami
  • Elise S Bales
  • MARK LADINSKY
  • Shannon Cain
  • Heide L Ford
  • Kiyoshi Kawakami
  • Erica L McCoy
  • Valerie Burns
  • John J Wysolmerski

Detail Information

Publications5

  1. pmc Dynamics and molecular determinants of cytoplasmic lipid droplet clustering and dispersion
    David J Orlicky
    Department of Pathology, University of Colorado School of Medicine, Aurora, Colorado, United States of America
    PLoS ONE 8:e66837. 2013
    ..Together these data suggest that the clustering and dispersion processes involve a complex orchestration of phosphorylation-dependent, microtubule-dependent and independent, and microfilament dependent steps. ..
  2. pmc Dynamic regulation of hepatic lipid droplet properties by diet
    Amanda E Crunk
    Graduate Program of Molecular Biology, University of Colorado School of Medicine, Aurora, Colorado, United States of America
    PLoS ONE 8:e67631. 2013
    ..These findings implicate CLD in the regulation of hepatic metabolic processes, and suggest that their properties undergo reorganization in response to hepatic metabolic demands. ..
  3. doi request reprint Lipid transport in the lactating mammary gland
    James L McManaman
    Division of Basic Reproductive Sciences, University of Colorado School of Medicine, Mail Stop 8613, 12700 E 19th Ave, Aurora, CO, 80045, USA
    J Mammary Gland Biol Neoplasia 19:35-42. 2014
    ....
  4. pmc Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease
    James L McManaman
    Division of Basic Reproductive Sciences, University of Colorado School of Medicine, Aurora, CO, USA
    J Lipid Res 54:1346-59. 2013
    ..Our study provides the first evidence that Plin2 contributes to HFD-induced obesity by modulating food intake, and that its absence prevents obesity-associated adipose tissue inflammatory foci and liver steatosis...
  5. pmc Characterization of the Six1 homeobox gene in normal mammary gland morphogenesis
    Ricardo D Coletta
    Department of Obstetrics and Gynecology, University of Colorado Denver, Anschutz Medical Campus, 12800 E, 19th Ave, Aurora, CO 80045, USA
    BMC Dev Biol 10:4. 2010
    ..However, because Six1 is highly expressed in the developing mammary gland, and because it has been implicated in the expansion of mammary stem cells, targeting Six1 as an anti-cancer therapy may have unwanted side effects in the breast...

Research Grants6

  1. MECHANISMS OF MILK LIPID SECRETION
    JAMES MCMANAMAN; Fiscal Year: 2004
    ..The mammary epithelial cell, because it can be manipulated by both transgenic and adenoviral technology, offers the opportunity to understand structure-function relations applicable to lipid storage in many cells and tissues. ..
  2. MECHANISMS OF MILK LIPID SECRETION
    JAMES MCMANAMAN; Fiscal Year: 2006
    ..The mammary epithelial cell, because it can be manipulated by both transgenic and adenoviral technology, offers the opportunity to understand structure-function relations applicable to lipid storage in many cells and tissues. ..
  3. MECHANISMS OF MILK LIPID SECRETION
    JAMES MCMANAMAN; Fiscal Year: 2007
    ..The mammary epithelial cell, because it can be manipulated by both transgenic and adenoviral technology, offers the opportunity to understand structure-function relations applicable to lipid storage in many cells and tissues. ..
  4. MECHANISMS OF MILK LIPID SECRETION
    JAMES MCMANAMAN; Fiscal Year: 2005
    ..The mammary epithelial cell, because it can be manipulated by both transgenic and adenoviral technology, offers the opportunity to understand structure-function relations applicable to lipid storage in many cells and tissues. ..
  5. MECHANISMS OF MILK LIPID SECRETION
    JAMES MCMANAMAN; Fiscal Year: 2009
    ....
  6. MECHANISMS OF MILK LIPID SECRETION
    JAMES LEWIS MCMANAMAN; Fiscal Year: 2010
    ....