Research Topics
Species | Robert J McMahonSummaryAffiliation: University of Florida Country: USA Publications
| Collaborators
|
Detail Information
Publications
Biotin in metabolism and molecular biologyRobert J McMahon
Center for Nutritional Sciences, Food Science and Human Nutrition Department, Institute of Food and Agricultural Science and the College of Agricultural and Life Sciences, University of Florida, Gainesville, Florida 32611 0370, USA
Annu Rev Nutr 22:221-39. 2002..Given mounting evidence of suboptimum biotin status, a more complete understanding of these aspects of biotin should lead to a greater appreciation of the ways in which biotin aids in the maintenance of health...
Pharmacological biotin supplementation maintains biotin status and function in rats administered dietary carbamazepineSara C Rathman
Center for Nutritional Sciences, University of Florida, Gainesville, FL 32611, USA
J Nutr 133:2857-62. 2003..These results support the use of biotin supplementation as a concurrent strategy during CBZ administration to help maintain biotin status, function of biotin-dependent enzymes and decrease CBZ-induced lactate accumulation...
Detection and quantification of biotinylated proteins using the Storm 840 Optical ScannerBrandon Lewis
Food Science and Human Nutrition Department, Institute of Food and Agricultural Sciences and the, College of Agricultural and Life Sciences, University of Florida, Gainesville, FL 32611-0370, USA
J Nutr Biochem 14:196-202. 2003..All systems demonstrated an ability to reliably detect and quantify biotinylated polypeptides in purified as well as complex samples, given careful attention to conditions optimized for each system...
Dietary carbamazepine administration decreases liver pyruvate carboxylase activity and biotinylation by decreasing protein and mRNA expression in ratsSara C Rathman
Center for Nutritional Sciences, Food Science and Human Nutrition Department, University of Florida, Gainesville, FL 32611, USA
J Nutr 133:2119-24. 2003..Taken together, the lower PC protein and mRNA expression provide a plausible biochemical mechanism to explain the decreased abundance of biotinylated hepatic PC observed in previous studies...
The abundance and function of biotin-dependent enzymes are reduced in rats chronically administered carbamazepineSara C Rathman
Center for Nutritional Sciences, Food Science and Human Nutrition Department, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL 32611, USA
J Nutr 132:3405-10. 2002....
Uptake, hydrolysis, and metabolism of pyridoxine-5'-beta-D-glucoside in Caco-2 cellsAmy D Mackey
Food Science and Human Nutrition Department, University of Florida, Gainesville, FL, USA
J Nutr 134:842-6. 2004..The presence of lactose in this in vitro model of intestinal uptake reduced the enzymatic hydrolysis of PNG by lactase...
Acute glucocorticoid treatment increases urinary biotin excretion and serum biotinSara C Rathman
The Center for Nutritional Science and The Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida 32611, USA
Am J Physiol Endocrinol Metab 282:E643-9. 2002..These results demonstrate the existence of potentially novel regulatory pathways for total biotin pools and the possibility that experimental models with high initial biotin status may mask potentially important regulatory mechanisms...
Zinc transporters 1, 2 and 4 are differentially expressed and localized in rats during pregnancy and lactationJuan P Liuzzi
Food Science and Human Nutrition Department, University of Florida, Gainesville, FL, USA
J Nutr 133:342-51. 2003..These results support a role for these transporters in maintaining an adequate zinc supply derived from the maternal diet for zinc acquisition and use by the fetus and neonate...
Diaminobiotin and desthiobiotin have biotin-like activities in Jurkat cellsRocio Rodriguez-Melendez
Department of Nutritional Science and Dietetics, University of Nebraska at Lincoln, Lincoln, NE, USA
J Nutr 133:1259-64. 2003..It is not known whether naturally occurring biotin metabolites also have biotin-like activities...
Organic glasses with exceptional thermodynamic and kinetic stabilityStephen F Swallen
Department of Chemistry, University of Wisconsin Madison, Madison, WI 53706, USA
Science 315:353-6. 2007..This technique provides an efficient means of producing glassy materials that are low on the energy landscape and could affect technologies such as amorphous pharmaceuticals...
