Samuel A McLean

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. pmc Incidence and predictors of neck and widespread pain after motor vehicle collision among US litigants and nonlitigants
    Samuel A McLean
    TRYUMPH Research Program, University of North Carolina, Chapel Hill, NC, USA Department of Anesthesiology, University of North Carolina, Chapel Hill, NC, USA Department of Emergency Medicine, University of North Carolina, Chapel Hill, NC, USA Electronic address
    Pain 155:309-21. 2014
  2. pmc Acute severe pain is a common consequence of sexual assault
    Samuel A McLean
    TRYUMPH Research Program, University of North Carolina, Chapel Hill, North Carolina 27599 7010, USA
    J Pain 13:736-41. 2012
  3. pmc The potential contribution of stress systems to the transition to chronic whiplash-associated disorders
    Samuel A McLean
    Department of Anesthesiology, N2201 UNC Hospitals, Chapel Hill, NC 27599 7010, USA
    Spine (Phila Pa 1976) 36:S226-32. 2011
  4. pmc Catechol O-methyltransferase haplotype predicts immediate musculoskeletal neck pain and psychological symptoms after motor vehicle collision
    Samuel A McLean
    Department of Anesthesiology, University of North Carolina, 101 Manning Drive, Chapel Hill, NC 27599, USA
    J Pain 12:101-7. 2011
  5. doi request reprint μ-Opioid receptor gene A118G polymorphism predicts pain recovery after sexual assault
    Lauren E Ballina
    TRYUMPH Research Program, University of North Carolina, Chapel Hill, North Carolina 27599 7010, USA
    J Pain 14:165-71. 2013
  6. pmc Polymorphisms in the glucocorticoid receptor co-chaperone FKBP5 predict persistent musculoskeletal pain after traumatic stress exposure
    Andrey V Bortsov
    TRYUMPH Research Program, University of North Carolina, Chapel Hill, NC, USA
    Pain 154:1419-26. 2013
  7. pmc Catechol-O-methyltransferase genotype predicts pain severity in hospitalized burn patients
    Danielle C Orrey
    Department of Anesthesiology and TRYUMPH Research Program, University of North Carolina, Chapel Hill, NC 27599 7455, USA
    J Burn Care Res 33:518-23. 2012
  8. pmc Side effects from oral opioids in older adults during the first week of treatment for acute musculoskeletal pain
    Katherine M Hunold
    Department of Biostatistics, University of North Carolina Chapel Hill, Chapel Hill, NC
    Acad Emerg Med 20:872-9. 2013
  9. pmc Using emergency department-based inception cohorts to determine genetic characteristics associated with long term patient outcomes after motor vehicle collision: methodology of the CRASH study
    Timothy F Platts-Mills
    Department of Anesthesiology, University of North Carolina, Chapel Hill, North Carolina, USA
    BMC Emerg Med 11:14. 2011
  10. pmc More educated emergency department patients are less likely to receive opioids for acute pain
    Timothy F Platts-Mills
    Department of Anesthesiology, University of North Carolina, Chapel Hill, NC 27599 7010, USA
    Pain 153:967-73. 2012

Collaborators

Detail Information

Publications22

  1. pmc Incidence and predictors of neck and widespread pain after motor vehicle collision among US litigants and nonlitigants
    Samuel A McLean
    TRYUMPH Research Program, University of North Carolina, Chapel Hill, NC, USA Department of Anesthesiology, University of North Carolina, Chapel Hill, NC, USA Department of Emergency Medicine, University of North Carolina, Chapel Hill, NC, USA Electronic address
    Pain 155:309-21. 2014
    ..These data demonstrate that persistent pain after MVC is common among those not engaged in litigation, and provide evidence for bidirectional influences between pain outcomes and litigation after MVC. ..
  2. pmc Acute severe pain is a common consequence of sexual assault
    Samuel A McLean
    TRYUMPH Research Program, University of North Carolina, Chapel Hill, North Carolina 27599 7010, USA
    J Pain 13:736-41. 2012
    ..These findings suggest that pain is common in SA survivors in the early postassault period, but rarely treated...
  3. pmc The potential contribution of stress systems to the transition to chronic whiplash-associated disorders
    Samuel A McLean
    Department of Anesthesiology, N2201 UNC Hospitals, Chapel Hill, NC 27599 7010, USA
    Spine (Phila Pa 1976) 36:S226-32. 2011
    ..A narrative description highlighting preclinical and clinical evidence that physiologic stress systems contribute to whiplash-associated disorders (WAD) pathogenesis...
  4. pmc Catechol O-methyltransferase haplotype predicts immediate musculoskeletal neck pain and psychological symptoms after motor vehicle collision
    Samuel A McLean
    Department of Anesthesiology, University of North Carolina, 101 Manning Drive, Chapel Hill, NC 27599, USA
    J Pain 12:101-7. 2011
    ..038). These findings suggest that genetic variations affecting stress response system function influence the somatic and psychological response to MVC, and provide the first evidence of genetic risk for clinical symptoms after MVC...
  5. doi request reprint μ-Opioid receptor gene A118G polymorphism predicts pain recovery after sexual assault
    Lauren E Ballina
    TRYUMPH Research Program, University of North Carolina, Chapel Hill, North Carolina 27599 7010, USA
    J Pain 14:165-71. 2013
    ....
  6. pmc Polymorphisms in the glucocorticoid receptor co-chaperone FKBP5 predict persistent musculoskeletal pain after traumatic stress exposure
    Andrey V Bortsov
    TRYUMPH Research Program, University of North Carolina, Chapel Hill, NC, USA
    Pain 154:1419-26. 2013
    ..These results suggest that glucocorticoid pathways influence the development of persistent posttraumatic pain, and that such pathways may be a target of pharmacologic interventions aimed at improving recovery after trauma...
  7. pmc Catechol-O-methyltransferase genotype predicts pain severity in hospitalized burn patients
    Danielle C Orrey
    Department of Anesthesiology and TRYUMPH Research Program, University of North Carolina, Chapel Hill, NC 27599 7455, USA
    J Burn Care Res 33:518-23. 2012
    ..These findings suggest that genetic factors influencing stress system function may have an important influence on pain severity after burn injury. Further studies of genetic predictors of pain after burn injury are needed...
  8. pmc Side effects from oral opioids in older adults during the first week of treatment for acute musculoskeletal pain
    Katherine M Hunold
    Department of Biostatistics, University of North Carolina Chapel Hill, Chapel Hill, NC
    Acad Emerg Med 20:872-9. 2013
    ..The authors sought to describe the frequency of short-term side effects experienced by older adults initiating treatment with opioid-containing analgesics for acute musculoskeletal pain...
  9. pmc Using emergency department-based inception cohorts to determine genetic characteristics associated with long term patient outcomes after motor vehicle collision: methodology of the CRASH study
    Timothy F Platts-Mills
    Department of Anesthesiology, University of North Carolina, Chapel Hill, North Carolina, USA
    BMC Emerg Med 11:14. 2011
    ....
  10. pmc More educated emergency department patients are less likely to receive opioids for acute pain
    Timothy F Platts-Mills
    Department of Anesthesiology, University of North Carolina, Chapel Hill, NC 27599 7010, USA
    Pain 153:967-73. 2012
    ..01). In this sample of post-MVC ED patients, more educated patients were less likely to receive opioids. Further study is needed to assess the generalizability of these findings and to determine the reason for the difference...
  11. pmc Pain treatment for older adults during prehospital emergency care: variations by patient gender and pain severity
    Timothy F Platts-Mills
    Department of Emergency Medicine, University of North Carolina, Chapel Hill, North Carolina, USA
    J Pain 14:966-74. 2013
    ..Further research is needed to assess the generalizability of this interaction between age, gender, and pain severity on pain treatment...
  12. pmc Older US emergency department patients are less likely to receive pain medication than younger patients: results from a national survey
    Timothy F Platts-Mills
    Department of Emergency Medicine, University of North Carolina Chapel Hill, Chapel Hill, NC, USA
    Ann Emerg Med 60:199-206. 2012
    ..The purpose of this study is to determine whether older adults presenting to the emergency department (ED) with pain are less likely to receive pain medication than younger adults...
  13. pmc Effect of catechol-O-methyltransferase polymorphism on response to propranolol therapy in chronic musculoskeletal pain: a randomized, double-blind, placebo-controlled, crossover pilot study
    Inna E Tchivileva
    Center for Neurosensory Disorders, School of Dentistry, University of North Carolina, Chapel Hill, NC 27599 7450, USA
    Pharmacogenet Genomics 20:239-48. 2010
    ..We hypothesized that the nonselective beta-adrenergic antagonist propranolol will reduce clinical and experimental pain in TMD patients in a manner dependent on the individuals' COMT diplotype...
  14. pmc Shared decision-making in the selection of outpatient analgesics for older individuals in the emergency department
    Cameron G Isaacs
    School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA
    J Am Geriatr Soc 61:793-8. 2013
    ....
  15. pmc Pain and interference of pain with function and mood in elderly adults involved in a motor vehicle collision: a pilot study
    Timothy F Platts-Mills
    Department of Emergency Medicine, University of North Carolina, Chapel Hill, Chapel Hill, NC 27599 7594, USA
    Exp Aging Res 38:330-43. 2012
    ....
  16. ncbi request reprint Emergency medical services use by the elderly: analysis of a statewide database
    Timothy F Platts-Mills
    Department of Emergency Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Prehosp Emerg Care 14:329-33. 2010
    ..To test the hypothesis that EMS use for emergency department (ED) transports increases across the life span and to estimate changes in the EMS volume in North Carolina (NC) during the next 20 years due to the aging of the population...
  17. pmc μ-Opioid receptor gene A118G polymorphism predicts survival in patients with breast cancer
    Andrey V Bortsov
    Department of Anesthesiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7010, USA
    Anesthesiology 116:896-902. 2012
    ..In this study we assessed the association between six common polymorphisms in the μ-opioid receptor gene, including the well known A118G polymorphism, and breast cancer survival...
  18. pmc Somatic symptoms among US adolescent females: associations with sexual and physical violence exposure
    Carolyn Tucker Halpern
    Department of Maternal and Child Health, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB 8120, Carolina Population Center, Chapel Hill, NC, 27599 8120, USA
    Matern Child Health J 17:1951-60. 2013
    ..Treating symptoms alone, without addressing the potential violence experienced, may not adequately improve adolescents' somatic complaints and well-being...
  19. pmc Complex multilocus effects of catechol-o-methyltransferase haplotypes predict pain and pain interference 6 weeks after motor vehicle collision
    Andrey V Bortsov
    TRYUMPH Research Program, University of North Carolina, Chapel Hill, NC, 27599, USA
    Neuromolecular Med 16:83-93. 2014
    ..These results suggest that genetic variants in the distal promoter are important contributors to the development of persistent pain after MVC, directly and via the interaction with haplotypes in the coding region of the gene. ..
  20. pmc Motor vehicle collision-related emergency department visits by older adults in the United States
    Timothy F Platts-Mills
    Department of Emergency Medicine, University of North Carolina Chapel Hill, Chapel Hill, NC, USA
    Acad Emerg Med 19:821-7. 2012
    ..The authors sought to determine these characteristics using information from two nationally representative data sets...
  21. doi request reprint Substantial postoperative pain is common among children undergoing laparoscopic appendectomy
    Maggie J Tomecka
    Department of Anesthesiology, University of North Carolina, Chapel Hill, NC 27599 7455, USA
    Paediatr Anaesth 22:130-5. 2012
    ..In this study, we assessed the postoperative pain experience of children undergoing laparoscopic appendectomy...
  22. doi request reprint Health status, not head injury, predicts concussion symptoms after minor injury
    Samuel A McLean
    Department of Emergency Medicine and the TRYUMPH Research Program, University of North Carolina, Chapel Hill, NC 27599 7455, USA
    Am J Emerg Med 27:182-90. 2009
    ..Postconcussion (PC) syndrome etiology remains poorly understood. We sought to examine predictors of persistent PC symptoms after minor injury...