MARY ANN A MCLANE

Summary

Affiliation: University of Delaware
Country: USA

Publications

  1. ncbi New insights on disintegrin-receptor interactions: eristostatin and melanoma cells
    M A McLane
    Department of Medical Technology, McKinly Lab 057, University of Delaware, Newark, DE 19716, USA
    Haemostasis 31:177-82. 2001
  2. ncbi Disintegrins
    Mary Ann McLane
    Department of Medical Technology, University of Delaware, Newark, DE 19716, USA
    Curr Drug Targets Cardiovasc Haematol Disord 4:327-55. 2004
  3. ncbi Scratching below the surface: wound healing and alanine mutagenesis provide unique insights into interactions between eristostatin, platelets and melanoma cells
    Mary Ann McLane
    Department of Medical Technology, University of Delaware, Newark, Del 19716, USA
    Pathophysiol Haemost Thromb 34:164-8. 2005
  4. ncbi Scientific and standardization committee communications: classification and nomenclature of disintegrins isolated from snake venoms
    M A McLane
    Department of Medical Technology, University of Delaware, Newark, DE 19716, USA
    J Thromb Haemost 5:1971. 2007
  5. ncbi Disintegrins in health and disease
    Mary Ann McLane
    Department of Medical Technology, University of Delaware, 305G Willard Hall Education Building, Newark, DE 19716, USA
    Front Biosci 13:6617-37. 2008
  6. ncbi Inhibition of melanoma cell motility by the snake venom disintegrin eristostatin
    Jing Tian
    Department of Medical Technology, University of Delaware, 305G Willard Hall, Education Building, Newark, DE 19716, USA
    Toxicon 49:899-908. 2007

Research Grants

  1. Melanoma Metastasis Inhibition by Eristostatin
    Mary Ann McLane; Fiscal Year: 2005

Collaborators

  • Elda E Sanchez
  • Jing Tian
  • E Helene Sage
  • Vivek Patel
  • Carrie Paquette-Straub
  • Deni Galileo
  • Sarah E Funk

Detail Information

Publications6

  1. ncbi New insights on disintegrin-receptor interactions: eristostatin and melanoma cells
    M A McLane
    Department of Medical Technology, McKinly Lab 057, University of Delaware, Newark, DE 19716, USA
    Haemostasis 31:177-82. 2001
    ..While it is known that eristostatin binds to alphaIIbbeta3 on platelets, the receptor with which eristostatin binds to the melanoma cells has not yet been identified...
  2. ncbi Disintegrins
    Mary Ann McLane
    Department of Medical Technology, University of Delaware, Newark, DE 19716, USA
    Curr Drug Targets Cardiovasc Haematol Disord 4:327-55. 2004
    ..The purpose of this review is to highlight the members of this disintegrin family discovered since 1998 as well as the increased understanding of their usefulness in therapeutics and technical assays...
  3. ncbi Scratching below the surface: wound healing and alanine mutagenesis provide unique insights into interactions between eristostatin, platelets and melanoma cells
    Mary Ann McLane
    Department of Medical Technology, University of Delaware, Newark, Del 19716, USA
    Pathophysiol Haemost Thromb 34:164-8. 2005
    ..However, phosphorylation studies performed after these melanoma cells were exposed to eristostatin revealed changes in several tyrosine phosphorylated molecules...
  4. ncbi Scientific and standardization committee communications: classification and nomenclature of disintegrins isolated from snake venoms
    M A McLane
    Department of Medical Technology, University of Delaware, Newark, DE 19716, USA
    J Thromb Haemost 5:1971. 2007
    ..The summary of these recommendations will provide guidance as disintegrin discoveries move beyond high pressure liquid chromatography (HPLC) separation methods to mass spectrometry, proteomics and cloned cDNA...
  5. ncbi Disintegrins in health and disease
    Mary Ann McLane
    Department of Medical Technology, University of Delaware, 305G Willard Hall Education Building, Newark, DE 19716, USA
    Front Biosci 13:6617-37. 2008
    ..This review will summarize disintegrin investigations since 2003...
  6. ncbi Inhibition of melanoma cell motility by the snake venom disintegrin eristostatin
    Jing Tian
    Department of Medical Technology, University of Delaware, 305G Willard Hall, Education Building, Newark, DE 19716, USA
    Toxicon 49:899-908. 2007
    ..For six of the mutations, however, decreased activity was found only in the latter assay. We conclude that a different mechanism and/or integrin is involved in these two cell activities...

Research Grants3

  1. Melanoma Metastasis Inhibition by Eristostatin
    Mary Ann McLane; Fiscal Year: 2005
    ..This information will, in turn, lead to a rational design of therapeutic agents which would target these cells. ..