T O McKinley

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. ncbi request reprint Trabecular bone strain changes associated with cartilage defects in the proximal and distal tibia
    T O McKinley
    Department of Orthopaedic Surgery, University of Iowa Health Care, Iowa City 52242, USA
    J Orthop Res 19:906-13. 2001
  2. pmc In vivo measurement of translational stiffness of rabbit knees
    Anneliese D Heiner
    Department of Orthopaedics and Rehabilitation, Biomechanics Laboratory, University of Iowa, 2181 Westlawn, Iowa City, IA 52242, USA
    J Biomech 40:2313-7. 2007
  3. pmc Instability-associated changes in contact stress and contact stress rates near a step-off incongruity
    Todd O McKinley
    Department of Orthopaedics and Rehabilitation, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    J Bone Joint Surg Am 90:375-83. 2008
  4. ncbi request reprint Contact stress transients during functional loading of ankle stepoff incongruities
    Todd O McKinley
    Department of Orthopaedic Surgery, University of Iowa Hospitals and Clinics, 01021 JPP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    J Biomech 39:617-26. 2006
  5. ncbi request reprint Incongruity-dependent changes of contact stress rates in human cadaveric ankles
    Todd O McKinley
    University of Iowa Department of Orthopaedics and Rehabilitation, Iowa City, IA 52242, USA
    J Orthop Trauma 20:732-8. 2006
  6. pmc The Bernese Periacetabular Osteotomy: review of reported outcomes and the early experience at the University of Iowa
    Todd O McKinley
    Department of Orthopaedic Surgery, University of Iowa Hospital and Clinics, 200 Hawkins Drive, Iowa City, Iowa 52242, USA
    Iowa Orthop J 23:23-8. 2003
  7. pmc The effect of incongruity and instability on contact stress directional gradients in human cadaveric ankles
    T O McKinley
    Orthopaedics Biomechanics Laboratory, Department of Orthopaedic Surgery, University of Iowa, Iowa City, IA 52242, USA
    Osteoarthritis Cartilage 16:1363-9. 2008
  8. ncbi request reprint Trabecular bone strain changes associated with subchondral comminution of the distal tibia
    Todd O McKinley
    Department of Orthopaedic Surgery, University of Iowa Hospital and Clinics, Iowa City, Iowa 52242, USA
    J Orthop Trauma 16:709-16. 2002
  9. pmc Basic science of intra-articular fractures and posttraumatic osteoarthritis
    Todd O McKinley
    Department of Orthopaedic Surgery, University of Iowa Hospitals, 200 Hawkins Drive, Iowa City, IA 52242, USA
    J Orthop Trauma 24:567-70. 2010
  10. ncbi request reprint Stance-phase aggregate contact stress and contact stress gradient changes resulting from articular surface stepoffs in human cadaveric ankles
    T O McKinley
    Department of Orthopaedic Surgery, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Osteoarthritis Cartilage 14:131-8. 2006

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Trabecular bone strain changes associated with cartilage defects in the proximal and distal tibia
    T O McKinley
    Department of Orthopaedic Surgery, University of Iowa Health Care, Iowa City 52242, USA
    J Orthop Res 19:906-13. 2001
    ..We postulate that disturbances in load transmission through the subchondral bone caused by cartilage defects may be important mechanical determinants of PTA...
  2. pmc In vivo measurement of translational stiffness of rabbit knees
    Anneliese D Heiner
    Department of Orthopaedics and Rehabilitation, Biomechanics Laboratory, University of Iowa, 2181 Westlawn, Iowa City, IA 52242, USA
    J Biomech 40:2313-7. 2007
    ....
  3. pmc Instability-associated changes in contact stress and contact stress rates near a step-off incongruity
    Todd O McKinley
    Department of Orthopaedics and Rehabilitation, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    J Bone Joint Surg Am 90:375-83. 2008
    ..It was hypothesized that joint instability, superimposed on articular incongruity, would cause significant increases in contact stresses and contact stress rates...
  4. ncbi request reprint Contact stress transients during functional loading of ankle stepoff incongruities
    Todd O McKinley
    Department of Orthopaedic Surgery, University of Iowa Hospitals and Clinics, 01021 JPP, 200 Hawkins Drive, Iowa City, IA 52242, USA
    J Biomech 39:617-26. 2006
    ..Measuring contact stresses and contact stress gradients during motion allowed potential incongruity-associated pathologic changes in loading that occur over the complete motion cycle to be investigated...
  5. ncbi request reprint Incongruity-dependent changes of contact stress rates in human cadaveric ankles
    Todd O McKinley
    University of Iowa Department of Orthopaedics and Rehabilitation, Iowa City, IA 52242, USA
    J Orthop Trauma 20:732-8. 2006
    ..Incongruity-associated changes in contact stress rates and incongruity-associated instability events may be important pathomechanical determinants of post-traumatic arthritis...
  6. pmc The Bernese Periacetabular Osteotomy: review of reported outcomes and the early experience at the University of Iowa
    Todd O McKinley
    Department of Orthopaedic Surgery, University of Iowa Hospital and Clinics, 200 Hawkins Drive, Iowa City, Iowa 52242, USA
    Iowa Orthop J 23:23-8. 2003
    ..Outcomes and complications are the primary focus of discussion. Operative data and complications from the first 36 patients undergoing the Bernese PAO at the University of Iowa have been comparable to those reported in the literature...
  7. pmc The effect of incongruity and instability on contact stress directional gradients in human cadaveric ankles
    T O McKinley
    Orthopaedics Biomechanics Laboratory, Department of Orthopaedic Surgery, University of Iowa, Iowa City, IA 52242, USA
    Osteoarthritis Cartilage 16:1363-9. 2008
    ..Measure incongruity and instability-associated changes in transient contact stress directional gradients in a human cadaveric ankle model...
  8. ncbi request reprint Trabecular bone strain changes associated with subchondral comminution of the distal tibia
    Todd O McKinley
    Department of Orthopaedic Surgery, University of Iowa Hospital and Clinics, Iowa City, Iowa 52242, USA
    J Orthop Trauma 16:709-16. 2002
    ..To measure trabecular bone strain changes resulting from three increasing subchondral bone defects in the distal tibia...
  9. pmc Basic science of intra-articular fractures and posttraumatic osteoarthritis
    Todd O McKinley
    Department of Orthopaedic Surgery, University of Iowa Hospitals, 200 Hawkins Drive, Iowa City, IA 52242, USA
    J Orthop Trauma 24:567-70. 2010
    ..This article reviews recent basic scientific progress investigating intraarticular fractures and fracture-related chondrocyte death and dysfunction...
  10. ncbi request reprint Stance-phase aggregate contact stress and contact stress gradient changes resulting from articular surface stepoffs in human cadaveric ankles
    T O McKinley
    Department of Orthopaedic Surgery, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Osteoarthritis Cartilage 14:131-8. 2006
    ..Determine how stepoff incongruities of the distal tibia affect aggregate (whole-cycle) contact stresses and contact stress gradients for a complete motion cycle in human cadaveric ankles...
  11. ncbi request reprint Characteristics of pedicle screw loading. Effect of surgical technique on intravertebral and intrapedicular bending moments
    T O McKinley
    Department of Orthopaedic Surgery, University of California, Davis, Sacramento, USA
    Spine (Phila Pa 1976) 24:18-24, discussion 25. 1999
    ..Screws left short of full insertion, placed off center in the sagittal plane of the pedicle, or less than 40 mm long developed increased intrapedicular bending moments...
  12. ncbi request reprint Kinematic and contact stress analysis of posterior malleolus fractures of the ankle
    Daniel C Fitzpatrick
    Department of Orthopaedic Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA, USA
    J Orthop Trauma 18:271-8. 2004
    ..To determine if there are measurable dynamic contact stress aberrations and kinematic abnormalities (instability) that have not been observed in conventional static loading studies of posterior malleolar ankle fractures...
  13. pmc N-acetylcysteine inhibits post-impact chondrocyte death in osteochondral explants
    James A Martin
    Orthopaedic Cell and Molecular Biology Laboratory, Department of Orthopaedics and Rehabilitation, The University of Iowa, 1182 ML, Iowa City, IA 52242, USA
    J Bone Joint Surg Am 91:1890-7. 2009
    ..We hypothesized that treatment with N-acetylcysteine soon after an impact injury would have significant chondrocyte-sparing effects and would prevent injury-induced proteoglycan losses...
  14. ncbi request reprint Trabecular bone strain changes associated with subchondral stiffening of the proximal tibia
    Todd O McKinley
    Department of Orthopaedic Surgery, University of Iowa Health Care, 200 Hawkins Drive 1020 JPP, Iowa City, IA 52242, USA
    J Biomech 36:155-63. 2003
    ..Our experiment provides direct experimental measurement of increases in trabecular bone strain caused by subchondral stiffening, however, the clinical and biologic importance of strain increases is unknown...
  15. pmc Correlation of dynamic cartilage contact stress aberrations with severity of instability in ankle incongruity
    Yuki Tochigi
    Department of Orthopedics and Rehabilitation, University of Iowa, 2181 Westlawn, Iowa City, IA 52242 1100, USA
    J Orthop Res 26:1186-93. 2008
    ..Given this linear relationship, even small instability events presumably involve appreciable abnormality in dynamic joint contact mechanics...
  16. ncbi request reprint The effect of bone quality on pedicle screw loading in axial instability. A synthetic model
    R F McLain
    Department of Orthopaedic Surgery, University of California Davis, Sacramento, USA
    Spine (Phila Pa 1976) 22:1454-60. 1997
    ..Bone density is likely to play a limited role in screw bending failure...
  17. pmc Mitochondrial electron transport and glycolysis are coupled in articular cartilage
    J A Martin
    Department of Orthopaedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, IA, USA
    Osteoarthritis Cartilage 20:323-9. 2012
    ..The objective of this study was to test this hypothesis by determining if rotenone, which inhibits ET and blocks oxidant production inhibits glycolytic ATP synthesis...
  18. pmc A finite element exploration of cartilage stress near an articular incongruity during unstable motion
    Curtis M Goreham-Voss
    Department of Mechanical Engineering, University of Iowa, Iowa City, IA 52242, USA
    J Biomech 40:3438-47. 2007
    ..1 to 117.9 MPa/s for unstable motion. In the most rapidly loaded sections of cartilage, the fluid was found to carry nearly all of the normal load, with the pressurization of the fluid resulting in high solid matrix tangential stresses...
  19. pmc Strain-dependent oxidant release in articular cartilage originates from mitochondria
    M J Brouillette
    Ignacio Ponseti Orthopaedic Cell Biology Lab, Department of Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA, USA
    Biomech Model Mechanobiol 13:565-72. 2014
    ..25 MPa. Our findings strongly suggest that ROS and mitochondrial oxidants contribute to cartilage mechanobiology...
  20. ncbi request reprint Complications of locking plate fixation in complex proximal tibia injuries
    Phinit Phisitkul
    Department of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    J Orthop Trauma 21:83-91. 2007
    ..To report the complications and pitfalls in the treatment of complex injuries of the proximal tibia when locking plates are used...
  21. ncbi request reprint Percutaneous reduction and fixation of displaced intra-articular calcaneus fractures
    Matthew DeWall
    Department of Orthopaedic Surgery and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    J Orthop Trauma 24:466-72. 2010
    ....
  22. ncbi request reprint Trabecular bone strain changes associated with subchondral bone defects of the tibial plateau
    Anthony N Brown
    Northwest Orthopedic Surgeons, Minneapolis, Minnesota, USA
    J Orthop Trauma 16:638-43. 2002
    ..To measure trabecular bone strain changes resulting from three increasing subchondral bone defects in the medial tibial plateau...