Research Topics
| R W McKennaSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Detail Information
Publications
Immunophenotypic analysis of hematogones (B-lymphocyte precursors) in 662 consecutive bone marrow specimens by 4-color flow cytometryR W McKenna
Dept of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
Blood 98:2498-507. 2001..Four-color flow cytometry with optimal combinations of antibodies consistently distinguishes between hematogones and neoplastic lymphoblasts...
Large cell lymphoma transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma. A flow cytometric analysis of seven casesS H Kroft
Dept of Pathology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9073, USA
Am J Clin Pathol 115:385-95. 2001..These findings indicate that DLBCL arising in CLL/SLL tends to retain a CLL immunophenotype, in contrast with de novo CD5+ large cell lymphomas that uncommonly express such a phenotype...
Prognostic significance of tumour-infiltrating T lymphocytes and T-cell subsets in de novo diffuse large B-cell lymphoma: a multiparameter flow cytometry studyY Xu
Department of Pathology, University of Texas Southwestern Medical Center, 3523 Harry Hines Blvd, Dallas, TX 75390-9072, USA
Br J Haematol 112:945-9. 2001..06). These results suggest that TIL-T, particularly CD4+ T cells, may play a role in the control of DLBCL, and measurement of T-cell percentage and T-cell subsets using FCI may be useful in predicting the clinical behaviour of DLBCL...
Immunophenotypic analysis of peripheral T-cell neoplasms. A multiparameter flow cytometric approachS Jamal
University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9073, USA
Am J Clin Pathol 116:512-26. 2001..These data indicate that most PTCNs are aberrant by multiparameter flow analysis. However, results must be interpreted within the context of thorough knowledge of the immunophenotypic spectrum of nonneoplastic T cells...
Precursor B-cell lymphoblastic lymphoma. A study of nine cases lacking blood and bone marrow involvement and review of the literatureA Maitra
Dept of Pathology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75235, USA
Am J Clin Pathol 115:868-75. 2001..Comparison with precursor B-cell acute lymphoblastic leukemia showed several overlapping features, although distinct differences were identified...
Clinicopathologic analysis of CD10+ and CD10- diffuse large B-cell lymphoma. Identification of a high-risk subset with coexpression of CD10 and bcl-2Y Xu
Dept of Pathology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9072, USA
Am J Clin Pathol 116:183-90. 2001..While CD10+ and CD10- DLBCLs are similar with regard to a variety of clinical and pathologic features, CD10 and bcl-2 coexpressing tumors are an extremely high-risk subset based on response to therapy and overall survival...
Multifaceted approach to the diagnosis and classification of acute leukemiasR W McKenna
Department of Pathology, University of Texas, Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9072, USA
Clin Chem 46:1252-9. 2000..With optimal application of these techniques in the diagnosis of acute leukemias, treatment strategies can be more specifically directed and new therapeutic approaches can be evaluated more effectively...
