R McKean-Cowdin

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. pmc Parental smoking and risk of childhood brain tumors by functional polymorphisms in polycyclic aromatic hydrocarbon metabolism genes
    Jessica L Barrington-Trimis
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, California, United States of America
    PLoS ONE 8:e79110. 2013
  2. ncbi request reprint Trends in childhood brain tumor incidence, 1973-2009
    Roberta McKean-Cowdin
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, 2001 N Soto St, Los Angeles, CA, 90089, USA
    J Neurooncol 115:153-60. 2013
  3. pmc DEXA measures of body fat percentage and acute phase proteins among breast cancer survivors: a cross-sectional analysis
    Anne Dee
    Department of Preventive Medicine, Room 418D 2001 Soto Street, MC9239, Los Angeles, CA 90089, USA
    BMC Cancer 12:343. 2012
  4. pmc Estrogenic botanical supplements, health-related quality of life, fatigue, and hormone-related symptoms in breast cancer survivors: a HEAL study report
    Huiyan Ma
    Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA
    BMC Complement Altern Med 11:109. 2011
  5. doi request reprint Ambient air pollution and brain cancer mortality
    Roberta McKean-Cowdin
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, Los Angeles, CA 90089 9175, USA
    Cancer Causes Control 20:1645-51. 2009
  6. pmc Associations between polymorphisms in DNA repair genes and glioblastoma
    Roberta McKean-Cowdin
    University of Southern California Norris Cancer Center, Los Angeles, CA 90033, USA
    Cancer Epidemiol Biomarkers Prev 18:1118-26. 2009
  7. pmc The ADRB3 Trp64Arg variant and obesity in African-American breast cancer cases
    R McKean-Cowdin
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033, USA
    Int J Obes (Lond) 31:1110-8. 2007
  8. ncbi request reprint BRCA1 variants in a family study of African-American and Latina women
    Roberta McKean-Cowdin
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, 1441 Eastlake Avenue MS 44, Los Angeles, CA 90089 9175, USA
    Hum Genet 116:497-506. 2005
  9. ncbi request reprint Declining cancer rates in the 1990s
    R McKean-Cowdin
    Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles 90033 0800, USA
    J Clin Oncol 18:2258-68. 2000
  10. ncbi request reprint Risk of endometrial cancer and estrogen replacement therapy history by CYP17 genotype
    R McKean-Cowdin
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles 90033 0800, USA
    Cancer Res 61:848-9. 2001

Detail Information

Publications33

  1. pmc Parental smoking and risk of childhood brain tumors by functional polymorphisms in polycyclic aromatic hydrocarbon metabolism genes
    Jessica L Barrington-Trimis
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, California, United States of America
    PLoS ONE 8:e79110. 2013
    ....
  2. ncbi request reprint Trends in childhood brain tumor incidence, 1973-2009
    Roberta McKean-Cowdin
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, 2001 N Soto St, Los Angeles, CA, 90089, USA
    J Neurooncol 115:153-60. 2013
    ..Changes in incidence rates of subtypes of tumors over this time period reflect changes both in classification of CBT and in diagnostic techniques...
  3. pmc DEXA measures of body fat percentage and acute phase proteins among breast cancer survivors: a cross-sectional analysis
    Anne Dee
    Department of Preventive Medicine, Room 418D 2001 Soto Street, MC9239, Los Angeles, CA 90089, USA
    BMC Cancer 12:343. 2012
    ..This study examines the association between percent body fat and SAA and CRP and the potential interaction with NSAID use and weight change...
  4. pmc Estrogenic botanical supplements, health-related quality of life, fatigue, and hormone-related symptoms in breast cancer survivors: a HEAL study report
    Huiyan Ma
    Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA
    BMC Complement Altern Med 11:109. 2011
    ..It remains unclear whether estrogenic botanical supplement (EBS) use influences breast cancer survivors' health-related outcomes...
  5. doi request reprint Ambient air pollution and brain cancer mortality
    Roberta McKean-Cowdin
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, Los Angeles, CA 90089 9175, USA
    Cancer Causes Control 20:1645-51. 2009
    ..Air pollution has been associated with respiratory disorders and cardiovascular morbidity and mortality, but associations between air pollutants and brain cancer have not been investigated in adults...
  6. pmc Associations between polymorphisms in DNA repair genes and glioblastoma
    Roberta McKean-Cowdin
    University of Southern California Norris Cancer Center, Los Angeles, CA 90033, USA
    Cancer Epidemiol Biomarkers Prev 18:1118-26. 2009
    ..Our results suggest that common variation in DNA repair genes may be associated with risk for glioblastoma multiforme...
  7. pmc The ADRB3 Trp64Arg variant and obesity in African-American breast cancer cases
    R McKean-Cowdin
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033, USA
    Int J Obes (Lond) 31:1110-8. 2007
    ....
  8. ncbi request reprint BRCA1 variants in a family study of African-American and Latina women
    Roberta McKean-Cowdin
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, 1441 Eastlake Avenue MS 44, Los Angeles, CA 90089 9175, USA
    Hum Genet 116:497-506. 2005
    ..We believe this to be the largest study of high-risk African-American and Latina women sequenced for variants in the BRCA1 gene to date...
  9. ncbi request reprint Declining cancer rates in the 1990s
    R McKean-Cowdin
    Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles 90033 0800, USA
    J Clin Oncol 18:2258-68. 2000
    ..To provide evidence of a substantial decline in cancer rates for the period 1991 through 1995 and characterize major risk factors that seem to be driving secular trends in cancer mortality and incidence...
  10. ncbi request reprint Risk of endometrial cancer and estrogen replacement therapy history by CYP17 genotype
    R McKean-Cowdin
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles 90033 0800, USA
    Cancer Res 61:848-9. 2001
    ..31; 95% CI, 0.53-3.21). These preliminary findings suggest that CYP17 or other variants in estrogen biosynthesis or metabolism pathways may be potential markers of endometrial cancer susceptibility due to ERT...
  11. pmc IGF1 genotype, mean plasma level and breast cancer risk in the Hawaii/Los Angeles multiethnic cohort
    K DeLellis
    Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, 90033 0800, USA
    Br J Cancer 88:277-82. 2003
    ..Research into relevant determinants of IGF1 levels in the blood must continue...
  12. ncbi request reprint Germ-line HER-2 variant and breast cancer risk by stage of disease
    R McKean-Cowdin
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, California 90089 9175, USA
    Cancer Res 61:8393-4. 2001
    ..Women with at least one copy of the Valine variant were approximately one-half as likely to have high-stage as low-stage breast cancer (P =.02), and this effect was present across racial/ethnic groups...
  13. ncbi request reprint Maternal prenatal exposure to nitrosatable drugs and childhood brain tumours
    Roberta McKean-Cowdin
    Department of Preventive Medicine, University of Southern, California, Norris Comprehensive Cancer Center, 1441 Eastlake Ave, PO Box 33800, MS 44, Los Angeles, CA 90033 0800, USA
    Int J Epidemiol 32:211-7. 2003
    ..We hypothesized that maternal ingestion of certain subgroups of nitrosatable drug products during pregnancy increases the risk of brain tumour development in offspring...
  14. pmc Four-year incidence and progression of diabetic retinopathy and macular edema: the Los Angeles Latino Eye Study
    Rohit Varma
    Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Am J Ophthalmol 149:752-61.e1-3. 2010
    ..To estimate the 4-year incidence and progression of diabetic retinopathy, macular edema (ME) and clinically significant macular edema (CSME) among adult Latinos with diabetes mellitus...
  15. pmc Four-year incidence and progression of visual impairment in Latinos: the Los Angeles Latino Eye Study
    Rohit Varma
    Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033 9224, USA
    Am J Ophthalmol 149:713-27. 2010
    ..To determine the 4-year incidence of visual impairment (VI) and blindness and worsening of visual acuity in adult Latinos and Hispanics aged 40 years and older...
  16. pmc Four-year incidence and progression of age-related macular degeneration: the Los Angeles Latino Eye Study
    Rohit Varma
    Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Am J Ophthalmol 149:741-51. 2010
    ..To estimate 4-year incidence and progression of early and advanced age-related macular degeneration (AMD)...
  17. pmc Central and peripheral visual impairment and the risk of falls and falls with injury
    Cecilia M Patino
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Ophthalmology 117:199-206.e1. 2010
    ..To evaluate whether central (CVI) and peripheral visual impairment (PVI) are independent risk factors for falls and falls with injury 4 years later...
  18. pmc Visual acuity norms in pre-school children: the Multi-Ethnic Pediatric Eye Disease Study
    Ying Pan
    Department of Ophthalmology, MPH Doheny Eye Institute, University of Southern California, Los Angeles, California 90033, USA
    Optom Vis Sci 86:607-12. 2009
    ....
  19. ncbi request reprint Impact of visual field loss on health-related quality of life in glaucoma: the Los Angeles Latino Eye Study
    Roberta McKean-Cowdin
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Ophthalmology 115:941-948.e1. 2008
    ..To examine the association between health-related quality of life (HRQOL) and visual field (VF) loss in participants with open-angle glaucoma (OAG) in the Los Angeles Latino Eye Study (LALES)...
  20. doi request reprint Effect of reproductive factors and oral contraceptives on breast cancer risk in BRCA1/2 mutation carriers and noncarriers: results from a population-based study
    Eunjung Lee
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Room 4407, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    Cancer Epidemiol Biomarkers Prev 17:3170-8. 2008
    ..However, the effects of these factors in BRCA1 and BRCA2 mutation carriers are less clear...
  21. pmc An association between a common variant (G972R) in the IRS-1 gene and sex hormone levels in post-menopausal breast cancer survivors
    Jing Fan
    Integrated Substance Abuse Programs, Neuropsychiatric Institute, University of California, 1640 S Sepulveda Boulevard, Suite 200, Los Angeles, CA 90025, USA
    Breast Cancer Res Treat 99:323-31. 2006
    ..02). No association was present for white patients. Our findings provide suggestive evidence that IRS-1 G972R variant may be associated with circulating levels of sex hormones and SHBG in African American breast cancer survivors...
  22. ncbi request reprint Reliability of demographic, smoking and occupational data provided by mothers vs. fathers in a childhood cancer study
    R McKean-Cowdin
    Department of Preventive Medicine, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles 90033 0800, USA
    Paediatr Perinat Epidemiol 14:257-62. 2000
    ..However, mothers were not reliably able to describe exposure to specific occupational agents...
  23. pmc Fixation preference and visual acuity testing in a population-based cohort of preschool children with amblyopia risk factors
    Susan A Cotter
    Doheny Eye Institute and the Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033 9224, USA
    Ophthalmology 116:145-53. 2009
    ..To compare the clinical assessment of fixation preference (FP) to visual acuity (VA) in a population-based sample of preschool children with amblyopia risk factors...
  24. pmc Serum organochlorines and breast cancer: a case-control study among African-American women
    Nicole M Gatto
    Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, USC Norris Comprehensive Center, 1441 Eastlake Avenue, Room 4449, Los Angeles, CA 90033, USA
    Cancer Causes Control 18:29-39. 2007
    ..This study, the largest study of African-American women to date, does not support a role of DDE and total PCBs in breast cancer risk at the levels measured...
  25. pmc Severity of visual field loss and health-related quality of life
    Roberta McKean-Cowdin
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Am J Ophthalmol 143:1013-23. 2007
    ..To examine the association between severity of visual field loss (VFL) and self-reported health-related quality of life (HRQOL) in a population-based sample...
  26. ncbi request reprint Prescription drug use and risk of acute myeloid leukemia by French-American-British subtype: results from a Los Angeles County case-control study
    Janice M Pogoda
    Keck School of Medicine, University of Southern California USC, Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Los Angeles, CA, USA
    Int J Cancer 114:634-8. 2005
    ..5, CI: 0.3, 9.0 for < or =6 months vs. OR = 5.0, CI: 0.6, 42.8 for >6 months). These results suggest that prescription drugs other than chemotherapy may have FAB subtype-specific effects on AML risk...
  27. pmc Longitudinal changes in visual acuity and health-related quality of life: the Los Angeles Latino Eye study
    Roberta McKean-Cowdin
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Ophthalmology 117:1900-7, 1907.e1. 2010
    ..To examine the association between longitudinal changes in visual acuity (VA) and health-related quality of life (HRQOL) in a population-based sample of adult Latinos...
  28. pmc Evaluation of unclassified variants in the breast cancer susceptibility genes BRCA1 and BRCA2 using five methods: results from a population-based study of young breast cancer patients
    Eunjung Lee
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, USC Norris Comprehensive Cancer Center, Los Angeles, CA 90089 9175, USA
    Breast Cancer Res 10:R19. 2008
    ....
  29. ncbi request reprint Maternal medication use and the risk of brain tumors in the offspring: the SEARCH international case-control study
    Amanda H Cardy
    Department of Public Health, University of Aberdeen, Aberdeen AB25 2ZD, Scotland, United Kingdom
    Int J Cancer 118:1302-8. 2006
    ..This is the largest case-control study of CBT and maternal medications to date. Our data provide little support for an association between maternal use of medications that may form NOC and subsequent development of CBT in the offspring...
  30. ncbi request reprint A haplotype-based case-control study of BRCA1 and sporadic breast cancer risk
    Matthew L Freedman
    Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
    Cancer Res 65:7516-22. 2005
    ....
  31. ncbi request reprint Concerning the CYP17 MspA1 polymorphism and breast cancer risk: a meta-analysis
    Heather Spencer Feigelson
    Mutagenesis 17:445-6; author reply 447-8. 2002
  32. ncbi request reprint Head circumference at birth linked to cancer in childhood
    Roberta McKean-Cowdin
    Lancet Oncol 7:4-5. 2006
  33. pmc Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium
    Melissa L Bondy
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 113:1953-68. 2008
    ..In this report, BTEC epidemiologists reviewed the group's consensus on the current state of scientific findings, and they present a consensus on research priorities to identify which important areas the science should move to address...