Research Topics
Species | Jonathan B McHughSummaryAffiliation: University of Michigan Country: USA Publications
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Detail Information
Publications
The clinical significance of focally enhanced gastritis in childrenJonathan B McHugh
Department of Pathology, University of Michigan, Ann Arbor, MI 48109 0054, USA
Am J Surg Pathol 37:295-9. 2013..The presence of FEG is highly associated with IBD in pediatric patients. The presence of FEG does not reliably distinguish between patients with CD and those with UC...
Atypical compound nevus arising in mature cystic ovarian teratomaJonathan B McHugh
Department of Pathology, University of Michigan, Ann Arbor, MI 48109 0054, USA
Med Sci Monit 12:CS34-7. 2006..Mature cystic ovarian teratoma (MCOT) is the most common primary ovarian tumor. Rarely, MCOT may undergo malignant transformation. Melanoma arising primarily in MCOT is a rare event. Melanocytic nevi have also rarely been reported in MCOT...
p63 immunohistochemistry differentiates salivary gland oncocytoma and oncocytic carcinoma from metastatic renal cell carcinomaJonathan B McHugh
Department of Pathology, University of Michigan Medical Center, 1500 E Medical Center Drive, Ann Arbor, MI 48109 0054, USA
Head Neck Pathol 1:123-31. 2007..While RCCm, CD10, and vimentin performed adequately, they were significantly less reliable than p63 with both false positives and false negatives...- Association of cystic neck metastases and human papillomavirus-positive oropharyngeal squamous cell carcinomaJonathan B McHugh
Department of Pathology, University of Michigan Health Systems, Ann Arbor, MI 48109, USA
Arch Pathol Lab Med 133:1798-803. 2009..Recognition of this unique clinicopathologic subset of head and neck carcinoma is important because these patients typically respond more favorably to organ-sparing treatment modalities and have an improved prognosis... - Update on selected salivary gland neoplasmsJonathan B McHugh
Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA
Arch Pathol Lab Med 133:1763-74. 2009..3% of all malignancies. In addition to their rarity, diagnosing these tumors can be challenging given the histologic overlap among various subtypes, their morphologic heterogeneity, and the recent recognition of new entities... - Sino-orbital osteoma: a clinicopathologic study of 45 surgically treated cases with emphasis on tumors with osteoblastoma-like featuresJonathan B McHugh
Department of Pathology, University of Michigan Health System, Ann Arbor, MI 48109 0054, USA
Arch Pathol Lab Med 133:1587-93. 2009..Osteomas may have osteoblastoma-like areas and distinguishing it from true osteoblastoma can be challenging. Some believe osteomas with osteoblastoma-like features behave more aggressively... - HPV-positive/p16-positive/EBV-negative nasopharyngeal carcinoma in white North AmericansJessica H Maxwell
University of Michigan Medical School, The University of Michigan Health System and Comprehensive Cancer Center, Ann Arbor, MI, USA
Head Neck 32:562-7. 2010..The HPV, p16, and EBV status was examined in current University of Michigan patients with NPC... - Head and neck squamous cell carcinoma in pregnant womenAnna M Eliassen
Department of Otolaryngology Head and Neck Surgery, The University of Michigan, Ann Arbor, Michigan, USA
Head Neck 35:335-42. 2013..The aim of this study was to investigate oral cancer in pregnant women, a rare but therapeutically challenging patient subset... - Comprehensive analysis of DNA methylation in head and neck squamous cell carcinoma indicates differences by survival and clinicopathologic characteristicsJustin A Colacino
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan, USA
PLoS ONE 8:e54742. 2013..These findings provide insight into the epigenetic regulation of viral vs. chemical carcinogenesis and could provide novel targets for development of individualized therapeutic and prevention regimens based on environmental exposures... - CT and MRI appearances and radiologic staging of pediatric renal cell carcinomaRyan T Downey
Department of Radiology, University of Michigan Health System, Ann Arbor, MI 48109, USA
Pediatr Radiol 42:410-7; quiz 513-4. 2012..There is a paucity of published data regarding the CT/MRI appearances and accuracy of pretreatment radiologic staging of this form of cancer in children... - Matted nodes: poor prognostic marker in oropharyngeal squamous cell carcinoma independent of HPV and EGFR statusMatthew E Spector
Departments of Otolaryngology Head and Neck Surgery, University of Michigan Health System, Ann Arbor, Michigan, USA
Head Neck 34:1727-33. 2012..Despite better prognosis, there is a group of oropharyngeal squamous cell carcinoma (SCC) human papillomavirus (HPV)+ patients who experience treatment failure and succumb to distant metastasis... - p63, CK7, PAX8 and INI-1: an optimal immunohistochemical panel to distinguish poorly differentiated urothelial cell carcinoma from high-grade tumours of the renal collecting systemJason C Carvalho
Department of Pathology, University of Michigan Medical Center, 1500 E Medical Center Drive, Ann Arbor, MI 48109 0602, USA
Histopathology 60:597-608. 2012..Accurate classification, especially the distinction of UC from RCC, is critical, as therapeutic approaches differ... - Fine-needle aspiration cytology of Rosai-Dorfman disease of boneXin Jing
Department of Pathology, University of Michigan Health System, Ann Arbor, Michigan 48109, USA
Diagn Cytopathol 36:516-8. 2008..The diagnosis was confirmed by concurrent biopsy with immunhistochemical study. Our case highlighted the role of fine-needle aspiration with ThinPrep technique in the diagnosis of Rosai-Dorfman disease... - Cross-sectional imaging of primary thoracic sarcomas with histopathologic correlation: a review for the radiologistJonathan R Dillman
Department of Radiology, University of Michigan Health System, C S Mott Children s Hospital, Section of Pediatric Radiology, Ann Arbor, MI 48109 0252, USA
Curr Probl Diagn Radiol 39:17-29. 2010..The purpose of this article is to review the various forms of primary sarcoma that may affect the thorax as well as illustrate pertinent cross-sectional radiologic findings with histopathologic correlation... - Napsin A is differentially expressed in sclerosing hemangiomas of the lungLindsay A Schmidt
Department of Pathology, University of Michigan Health System, Ann Arbor, MI 48109 0054, USA
Arch Pathol Lab Med 136:1580-4. 2012.... - Cutaneous and subcutaneous pleomorphic liposarcoma: a clinicopathologic study of 29 cases with evaluation of MDM2 gene amplification in 26Jerad M Gardner
Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA
Am J Surg Pathol 36:1047-51. 2012..The low incidence of MDM2 gene amplification in our series indicates that most superficial PLs are unrelated to WDL/DL. PL likely evolves by way of more than 1 molecular pathway... - Tobacco use in human papillomavirus-positive advanced oropharynx cancer patients related to increased risk of distant metastases and tumor recurrenceJessica H Maxwell
Departments of Otolaryngology Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA
Clin Cancer Res 16:1226-35. 2010.... - UM-SCC-104: a new human papillomavirus-16-positive cancer stem cell-containing head and neck squamous cell carcinoma cell lineAlice L Tang
Department of Otolaryngology Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA
Head Neck 34:1480-91. 2012..We established University of Michigan-squamous cell carcinoma-104 (UM-SCC-104), a new HPV(+) HNSCC cell line from a recurrent oral cavity tumor, and characterized it for the presence of cancer stem cells (CSCs)... - Synchronous ipsilateral sebaceous lymphadenoma and membranous basal cell adenoma of the parotidErica L Scheller
Department of Periodontics and Oral Medicine, University of Michigan, Ann Arbor, Michigan, USA
Oral Surg Oral Med Oral Pathol Oral Radiol 115:e41-6. 2013..In this report, we present the case with its management, followed by a discussion of the histopathologic nature of each tumor including the possible overlap between these two entities... - Effect of abrupt substitution of gadobenate dimeglumine for gadopentetate dimeglumine on rate of allergic-like reactionsMatthew S Davenport
Department of Radiology, B2 A209P, University of Michigan Health System, 1500 E Medical Center Dr, Ann Arbor, MI 48103, USA
Radiology 266:773-82. 2013..To evaluate the effect of abruptly substituting gadobenate dimeglumine for gadopentetate dimeglumine on allergic-like reactions... - Pilomatrixoma of the forearm: a case reportMichael V Birman
Department of Orthopaedic Surgery, University of Michigan, Ann Arbor 48109 5328, USA
Iowa Orthop J 29:121-3. 2009..We present the case of a 52-year-old woman with a pilomatrixoma of the forearm, and we review the literature regarding pilomatrixomas in the upper extremity... - Sinonasal glomangiopericytoma: case report with emphasis on the differential diagnosisMonisha Dandekar
Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA
Arch Pathol Lab Med 134:1444-9. 2010..We report the case of a 48-year-old woman with epistaxis and nasal obstruction who was diagnosed with glomangiopericytoma and discuss the histologic differential diagnosis... - Pathology quiz case. Nasal hamartoma, fibroglandular typeJonathan G Thomas
University of Michigan Medical School, Ann Arbor, Michigan, USA
Arch Otolaryngol Head Neck Surg 134:783-5. 2008 - Pretreatment dietary intake is associated with tumor suppressor DNA methylation in head and neck squamous cell carcinomasJustin A Colacino
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI, USA
Epigenetics 7:883-91. 2012..These preliminary results suggest that intake of folate, vitamin A and vitamin B12 may be associated with the tumor DNA methylation profile in HNC and enhance tumor suppression... - Complete devascularization of a juvenile angiofibroma by direct percutaneous embolization with only ethylene vinyl alcohol copolymer (Onyx) through a single needle placementJoseph J Gemmete
Department of Interventional Neuroradiology, University of Michigan Hospitals, Ann Arbor, MI, USA
J Neurointerv Surg 3:191-3. 2011..A midfacial degloving and medial maxillectomy/maxillotomy was then performed and the tumor extirpated with blunt finger dissection and the assistance of an endoscope, with 200 ml of blood loss... - Dedifferentiated liposarcoma with inflammatory myofibroblastic tumor-like featuresDavid R Lucas
Department of Pathology, University of Michigan, Ann Arbor, MI 48109 0054, USA
Am J Surg Pathol 34:844-51. 2010..Awareness of this finding can prevent one from misdiagnosing dedifferentiated liposarcoma as inflammatory myofibroblastic tumor, a much less aggressive neoplasm... - Can lymphangiosarcoma be resurrected? A clinicopathological and immunohistochemical study of lymphatic differentiation in 49 angiosarcomasCohra C Mankey
Department of Pathology, University of Michigan, Ann Arbor, MI 48109 0054, USA
Histopathology 56:364-71. 2010..The aim was to investigate further lymphatic antigen expression, and to explore the relation of immunohistochemistry to morphological and clinical findings... - Primary versus radiation-associated craniofacial osteosarcoma: Biologic and clinicopathologic comparisonsJonathan B McHugh
Department of Pathology, University of Michigan, Ann Arbor, Michigan 48109-0054, USA
Cancer 107:554-62. 2006..In addition, they demonstrate higher expression rates of adverse prognostic indicators, further highlighting the distinction... - Cutaneous adnexal differentiation and stromal metaplasia in palate pleomorphic adenomas: a potential diagnostic pitfall that may be mistaken for malignancyLindsay A Schmidt
Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA
Am J Surg Pathol 34:1205-10. 2010..When cutaneous adnexal differentiation occurs in salivary gland pleomorphic adenomas, it can present a diagnostic pitfall that must not be misinterpreted as carcinoma at biopsy, fine needle aspiration, or frozen section... - Recurrent orbital schwannomas: clinical course and histopathologic correlationMichelle Kron
University of Michigan Medical School, Ann Arbor, MI, USA
BMC Ophthalmol 12:44. 2012..The presence of multiple schwannomas in a single patient suggests possible association with neurofibromatosis type 2 (NF2) or schwannomatosis... - The diagnostic value of endoscopic terminal ileum biopsiesJonathan B McHugh
Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA
Am J Gastroenterol 102:1084-9. 2007..We see many such biopsies in our gastrointestinal pathology service and have been impressed by the subjectively low yield of TI biopsies. Therefore, we studied this to obtain objective data... - Comparison of MR enterography and histopathology in the evaluation of pediatric Crohn diseaseJonathan R Dillman
Department of Radiology, CS Mott Children s Hospital, Section of Pediatric Radiology, University of Michigan Health System, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
Pediatr Radiol 41:1552-8. 2011..While MR enterography (MRE) is commonly used to identify segments of bowel affected by Crohn disease in children, there is little data to support this practice... - Clinical and pathologic predictors of recurrence and survival in spindle cell squamous cell carcinomaMatthew E Spector
Department of Otolaryngology Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA
Otolaryngol Head Neck Surg 145:242-7. 2011..To determine clinicopathologic predictors of recurrence and survival in patients with spindle cell squamous cell carcinoma (SpSCC)... - Expression of polycomb group protein EZH2 in nevi and melanomaJonathan B McHugh
Department of Pathology, University of Michigan, 1301 Catherine Road, Ann Arbor, MI 48109, USA
J Cutan Pathol 34:597-600. 2007..We sought to determine the pattern of EZH2 expression in benign and malignant melanocytic tumors to see if EZH2 might play a role in melanoma pathogenesis and progression...