Timothy McGuire

Summary

Affiliation: University of Nebraska Medical Center
Country: USA

Publications

  1. ncbi request reprint The effect of hydroxyurea on the phosphorylation of zidovudine and lamivudine in human umbilical vein endothelial cells
    Timothy R McGuire
    University of Nebraska Medical Center, College of Pharmacy, Omaha, Nebraska 68198 6045, USA
    In Vitro Cell Dev Biol Anim 39:280-2. 2003
  2. doi request reprint Clinically important interaction between statin drugs and Clostridium difficile toxin?
    Timothy McGuire
    College of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198 6045, United States
    Med Hypotheses 73:1045-7. 2009
  3. ncbi request reprint Anti-inflammatory Effects of Rosuvastatin in Healthy Subjects: A Prospective Longitudinal Study
    Timothy R McGuire
    University of Nebraska Medical Center, Department of Pharmacy Practice, Omaha, NE 68198 6045
    Curr Pharm Des 20:1156-60. 2014
  4. doi request reprint Inflammation associated with obesity: relationship with blood and bone marrow endothelial cells
    Timothy R McGuire
    Department of Pharmacy Practice, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska, USA
    Obesity (Silver Spring) 19:2130-6. 2011
  5. ncbi request reprint High-dose cyclophosphamide in multiple sclerosis patients undergoing autologous stem cell transplantation
    Timothy R McGuire
    Department of Pharmacy Practice, University of Nebraska Medical Center, 986045, Omaha, NE 68198 6045, USA
    Int Immunopharmacol 3:279-83. 2003
  6. ncbi request reprint Accessing rural populations: role of the community pharmacist in a breast and cervical cancer screening programme
    Timothy R McGuire
    Department of Pharmacy Practice, University of Medical Center College of Pharmacy, Omaha, NE 68198 6045, USA
    J Eval Clin Pract 13:146-9. 2007
  7. ncbi request reprint Release of TNF-alpha and IL-1beta from porcine brain endothelium corresponds to the pyrogenic potential of three marketed formulations of amphotericin
    T R McGuire
    Department of Pharmacy Practice, University of Nebraska College of Pharmacy, University of Nebraska Medical Center, Omaha, NE, USA
    Inflamm Res 54:375-9. 2005
  8. ncbi request reprint Release of prostaglandin E-2 in bovine brain endothelial cells after exposure to three unique forms of the antifungal drug amphotericin-B: role of COX-2 in amphotericin-B induced fever
    Timothy R McGuire
    Department of Pharmacy Practice, University of Nebraska College of Pharmacy, 986045 Nebraska Medical Center, Omaha, NE 68198 6045, USA
    Life Sci 72:2581-90. 2003
  9. doi request reprint Reduction in mortality associated with statin therapy in patients with severe sepsis
    Paul P Dobesh
    College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska 68198 6045, USA
    Pharmacotherapy 29:621-30. 2009
  10. doi request reprint Effects of exercise on hematological parameters, circulating side population cells, and cytokines
    Gina G Wardyn
    Department of Internal Medicine, Pulmonary Section, University of Nebraska Medical Center, Omaha, NE 68198 2055, USA
    Exp Hematol 36:216-23. 2008

Detail Information

Publications10

  1. ncbi request reprint The effect of hydroxyurea on the phosphorylation of zidovudine and lamivudine in human umbilical vein endothelial cells
    Timothy R McGuire
    University of Nebraska Medical Center, College of Pharmacy, Omaha, Nebraska 68198 6045, USA
    In Vitro Cell Dev Biol Anim 39:280-2. 2003
    ..There is improved production of the active antiviral 3TC triphosphate with HU pretreatment. The combination may be beneficial in treating potential sanctuary sites such as endothelium...
  2. doi request reprint Clinically important interaction between statin drugs and Clostridium difficile toxin?
    Timothy McGuire
    College of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198 6045, United States
    Med Hypotheses 73:1045-7. 2009
    ..The weight of the evidence leads to our hypothesis that statins interact with C difficile toxin A and B causing an increase in the rate and severity of CDAD...
  3. ncbi request reprint Anti-inflammatory Effects of Rosuvastatin in Healthy Subjects: A Prospective Longitudinal Study
    Timothy R McGuire
    University of Nebraska Medical Center, Department of Pharmacy Practice, Omaha, NE 68198 6045
    Curr Pharm Des 20:1156-60. 2014
    ..Significance: The decline in tlr-4 expression on blood monocytes and TNF-α plasma concentrations after 3 weeks of rosuvastatin treatment suggest a potential mechanism for the anti-inflammatory activity of rosuvastatin. ..
  4. doi request reprint Inflammation associated with obesity: relationship with blood and bone marrow endothelial cells
    Timothy R McGuire
    Department of Pharmacy Practice, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska, USA
    Obesity (Silver Spring) 19:2130-6. 2011
    ..These effects of obesity may be a potential mechanism for impaired tissue repair in obese patients...
  5. ncbi request reprint High-dose cyclophosphamide in multiple sclerosis patients undergoing autologous stem cell transplantation
    Timothy R McGuire
    Department of Pharmacy Practice, University of Nebraska Medical Center, 986045, Omaha, NE 68198 6045, USA
    Int Immunopharmacol 3:279-83. 2003
    ..In conclusion, in this small case series, there was no indication that CTX metabolism was different than that in other populations undergoing transplantation...
  6. ncbi request reprint Accessing rural populations: role of the community pharmacist in a breast and cervical cancer screening programme
    Timothy R McGuire
    Department of Pharmacy Practice, University of Medical Center College of Pharmacy, Omaha, NE 68198 6045, USA
    J Eval Clin Pract 13:146-9. 2007
    ..The article describes a demonstration project which used community pharmacists to educate and enrol low to moderate income and medically under-served women into a statewide breast and cervical cancer screening programme...
  7. ncbi request reprint Release of TNF-alpha and IL-1beta from porcine brain endothelium corresponds to the pyrogenic potential of three marketed formulations of amphotericin
    T R McGuire
    Department of Pharmacy Practice, University of Nebraska College of Pharmacy, University of Nebraska Medical Center, Omaha, NE, USA
    Inflamm Res 54:375-9. 2005
    ..Formulations of amphotericin include a deoxycholate suspension (d-Amph), an amphotericin-B lipid complex (Ablc), and a liposomal product (L-Amph). Fever is most frequent with d-Amph, intermediate with Ablc, and lowest with L-Amph...
  8. ncbi request reprint Release of prostaglandin E-2 in bovine brain endothelial cells after exposure to three unique forms of the antifungal drug amphotericin-B: role of COX-2 in amphotericin-B induced fever
    Timothy R McGuire
    Department of Pharmacy Practice, University of Nebraska College of Pharmacy, 986045 Nebraska Medical Center, Omaha, NE 68198 6045, USA
    Life Sci 72:2581-90. 2003
    ....
  9. doi request reprint Reduction in mortality associated with statin therapy in patients with severe sepsis
    Paul P Dobesh
    College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska 68198 6045, USA
    Pharmacotherapy 29:621-30. 2009
    ..To evaluate the effect of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) on mortality in patients with severe sepsis...
  10. doi request reprint Effects of exercise on hematological parameters, circulating side population cells, and cytokines
    Gina G Wardyn
    Department of Internal Medicine, Pulmonary Section, University of Nebraska Medical Center, Omaha, NE 68198 2055, USA
    Exp Hematol 36:216-23. 2008
    ....