Research Topics
| MATTHEW K MCGUESummaryAffiliation: University of Minnesota Country: USA Publications
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Detail Information
Publications
Genetic and environmental contributions to depression symptomatology: evidence from Danish twins 75 years of age and olderM McGue
Department of Psychology, University of Minnesota, Minneapolis 55455, USA
J Abnorm Psychol 106:439-48. 1997..The implications of these findings for understanding the nature of late-life depression symptomatology are discussed...- The association of early adolescent problem behavior with adult psychopathologyMatt McGue
Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
Am J Psychiatry 162:1118-24. 2005..g., early alcohol use with adult alcohol abuse)... - The environments of adopted and non-adopted youth: evidence on range restriction from the Sibling Interaction and Behavior Study (SIBS)Matt McGue
Department of Psychology, University of Minnesota, 75 East River Rd, Minneapolis, MN 55455, USA
Behav Genet 37:449-62. 2007..These data support the use of adoption studies to obtain direct estimates of the importance of shared environmental effects on psychological development... - The heritability of level and rate-of-change in cognitive functioning in Danish twins aged 70 years and olderMatt McGue
Department of Psychology, University of Minnesota, Minneapolis, 55455, USA
Exp Aging Res 28:435-51. 2002..00 to .57). These findings suggest that the search for specific genes might reasonably focus on average level of cognitive performance, whereas specific environmental influences might account for cognitive change... - Origins and consequences of age at first drink. II. Familial risk and heritabilityM McGue
Department of Psychology, University of Minnesota, Minneapolis, Minnesota 55455, USA
Alcohol Clin Exp Res 25:1166-73. 2001..We tested the common-inherited-vulnerability hypothesis by determining whether AFD is familial and heritable... - Origins and consequences of age at first drink. I. Associations with substance-use disorders, disinhibitory behavior and psychopathology, and P3 amplitudeM McGue
Department of Psychology, University of Minnesota, Minneapolis, Minnesota 55455, USA
Alcohol Clin Exp Res 25:1156-65. 2001..We investigated whether the association of age at first drink (AFD) with alcoholism was more consistent with the hypothesis that the former causes the latter or the hypothesis that both are manifestations of some common vulnerability... - The heritability of cognitive functioning in very old adults: evidence from Danish twins aged 75 years and olderM McGue
Department of Psychology, University of Minnesota, Minneapolis 55455, USA
Psychol Aging 16:272-80. 2001..These results replicate G. E. McClearn et al.'s (1997) study in indicating substantial genetic influences on late-life cognitive functioning... - Genetic and environmental influences on human behavioral differencesM McGue
Department of Psychology and Institute of Human Genetics, University of Minnesota, Minneapolis 55455, USA
Annu Rev Neurosci 21:1-24. 1998..Behavioral genetic research supports the heritability, not the genetic determination, of behavior... - The heritability of depression symptoms in elderly Danish twins: occasion-specific versus general effectsMatt McGue
Department of Psychology, University of Minnesota, Minneapolis, Minnesota 55455, USA
Behav Genet 33:83-93. 2003.... - Personality and substance use disorders: II. Alcoholism versus drug use disordersM McGue
Department of Psychology, University of Minnesota, Minneapolis 55455, USA
J Consult Clin Psychol 67:394-404. 1999..These findings suggest that the elevated levels of behavioral disinhibition observed with alcoholic individuals may be attributable to a subset of alcoholic individuals who also abuse drugs other than alcohol... - Genetic and environmental influences on adolescent substance use and abuseM McGue
Department of Psychology, University of Minnesota, Minneapolis, Minnesota 55455, USA
Am J Med Genet 96:671-7. 2000..The finding of significant environmental influences on all substance use measures underscores the importance of intervention on early adolescent substance use, a known predictor of adult substance abuse and dependence... 
Father-child transmission of antisocial behavior: the moderating role of father's presence in the homeRyan W Blazei
Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
J Am Acad Child Adolesc Psychiatry 47:406-15. 2008..To demonstrate an environmental effect of being raised by an antisocial father and to test whether the transmission of antisocial behavior from father to child is moderated by the father's presence in the home...
Environmental contributions to the stability of antisocial behavior over time: are they shared or non-shared?S Alexandra Burt
Department of Psychology, Michigan State University, East Lansing, MI, USA
J Abnorm Child Psychol 38:327-37. 2010..Such results provide an important constructive replication of prior research, strongly suggesting that shared environmental contributions to antisocial behavior are systematic in nature...- Genes mediate the association between P3 amplitude and externalizing disordersBrian M Hicks
Department of Psychology, University of Minnesota, Minneapolis, Minnesota 55455, USA
Psychophysiology 44:98-105. 2007..22. Results replicated across the two age cohorts and demonstrate that reduced P3 amplitude is a marker of the biological vulnerability to externalizing disorders... - Parental divorce and adolescent delinquency: ruling out the impact of common genesS Alexandra Burt
Department of Psychology, Michigan State University, East Lansing, MI 48824, USA
Dev Psychol 44:1668-77. 2008..Results firmly supported the latter, suggesting that it is the experience of parental divorce, and not common genes, that drives the association between divorce and adolescent delinquency... - Environmental contributions to adolescent delinquency: a fresh look at the shared environmentS Alexandra Burt
Department of Psychology, Michigan State University, 107D Psychology Building, East Lansing, MI 48824, USA
J Abnorm Child Psychol 35:787-800. 2007..Such findings provide an important extension of previous twin studies, as they suggest that passive genotype-environment correlations do not explain earlier findings of shared environmental influences on this association... - Nonshared environmental mediation of the association between deviant peer affiliation and adolescent externalizing behaviors over time: results from a cross-lagged monozygotic twin differences designS Alexandra Burt
Department of Psychology, Michigan State University, East Lansing, MI 48824, USA
Dev Psychol 45:1752-60. 2009..Implications are discussed... - Heritability of body height and educational attainment in an international context: comparison of adult twins in Minnesota and FinlandKarri Silventoinen
Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
Am J Hum Biol 16:544-55. 2004..Nonfamilial factors affecting education are possibly different in Minnesota than in Finland, since in Finland they are partly associated with the factors affecting height... - P300 amplitude in adolescent twins discordant and concordant for alcohol use disordersScott R Carlson
Department of Psychology, University of Minnesota, N218 Elliot Hall, 75 East River Road, Minneapolis, MN 55455, USA
Biol Psychol 61:203-27. 2002..The findings are consistent with P300 amplitude being a marker of vulnerability to alcohol use disorders... - The effects of childhood disruptive disorder comorbidity on P3 event-related brain potentials in preadolescents with ADHDHenry H Yoon
University of Minnesota, Twin Cities, 75 East River Road, Minneapolis, MN 55455, United States
Biol Psychol 79:329-36. 2008.... - Modeling the impact of age and sex on a dimension of poly-substance use in adolescence: a longitudinal study from 11- to 17-years-oldJaime Derringer
Department of Psychology, Washington University, St Louis, MO 63130, USA
Drug Alcohol Depend 110:193-9. 2010..This suggests that measurement and interpretation of adolescent substance use is enhanced by the consideration of a wide range of substances... - Genetic and environmental influences on disordered eating: An adoption studyKelly L Klump
Department of Psychology, Michigan State University, East Lansing, 48824 1116, USA
J Abnorm Psychol 118:797-805. 2009..Shared environmental factors did not contribute significantly to any disordered eating symptom. Our findings bolster those from twin studies and provide critical evidence of significant genetic effects on disordered eating symptoms... - Timing of menarche and the origins of conduct disorderS Alexandra Burt
Department of Psychology, Michigan State University, East Lansing, MI 48824, USA
Arch Gen Psychiatry 63:890-6. 2006.... - The different origins of stability and change in antisocial personality disorder symptomsS Alexandra Burt
Department of Psychology, Michigan State University, East Lansing, MI 48824, USA
Psychol Med 37:27-38. 2007..To date, however, researchers have yet to resolve the origins of either stability or change in antisocial behavior from childhood/adolescence to adulthood... - Using the brain P300 response to identify novel phenotypes reflecting genetic vulnerability for adolescent substance misuseHenry H Yoon
University of Minnesota, Twin Cities, 75 East River Road, Minneapolis, MN 55455, United States
Addict Behav 31:1067-87. 2006.... - A longitudinal investigation of the relationship between disordered eating attitudes and behaviors and parent-child conflict: a monozygotic twin differences designAlexia Spanos
Department of Psychology, Michigan State University, East Lansing, MI 48824 1116, USA
J Abnorm Psychol 119:293-9. 2010..Findings suggest differences in parent-child conflict between genetically identical twins may be a consequence of, rather than a risk factor for, differences in disordered eating... - Shared transmission of eating disorders and anxiety disordersPamela K Keel
Department of Psychology, University of Iowa, Iowa City, Iowa 55242, USA
Int J Eat Disord 38:99-105. 2005..Using twins from the population-based Minnesota Twin Family Study (MTFS), we examined comorbidity and shared transmission between eating pathology and these disorders... - Drinks of the father: father's maximum number of drinks consumed predicts externalizing disorders, substance use, and substance use disorders in preadolescent and adolescent offspringStephen M Malone
University of Minnesota, Minneapolis 55455, USA
Alcohol Clin Exp Res 26:1823-32. 2002..This phenotype might supplement DSM diagnoses of alcohol dependence to reduce the number of false positives in genetic research... - Trajectories of change in adolescent substance use and symptomatology: impact of paternal and maternal substance use disordersBrent Walden
Department of Psychology, University of Minnesota, Twin Cities Campus, Minneapolis, MN 55455, USA
Psychol Addict Behav 21:35-43. 2007..There was evidence for an additive, rather than interactive, combined parental effect. Findings help clarify the impact of paternal and maternal SUD on the development of substance involvement during adolescence... - Changes in genetic and environmental influences on disordered eating across adolescence: a longitudinal twin studyKelly L Klump
Department of Psychology, Michigan State University, 107B Psychology Building, East Lansing, MI 48824 1116, USA
Arch Gen Psychiatry 64:1409-15. 2007..Previous research suggests substantial increases in genetic effects on disordered eating across adolescence. Unfortunately, these studies were cross-sectional and focused primarily on early (age 11 years) vs late (age 17 years) adolescence... - Parental alcohol dependence and the transmission of adolescent behavioral disinhibition: a study of adoptive and non-adoptive familiesSerena M King
Department of Psychology, Hamline University, St Paul, MN, USA
Addiction 104:578-86. 2009..To examine the genetic and environmental influences of parental alcoholism on offspring disinhibited behavior... - Growth curve models for indistinguishable dyads using multilevel modeling and structural equation modeling: the case of adolescent twins' conflict with their mothersDeborah A Kashy
Department of Psychology, Michigan State University, East Lansing, MI 48824, USA
Dev Psychol 44:316-29. 2008..They illustrate modeling issues using an overtime study of adolescent twins' conflict with their mothers, a substantively important topic given the enduring interest in parent-child relationships during adolescence... - Sources of covariation among the child-externalizing disorders: informant effects and the shared environmentS Alexandra Burt
Department of Psychology, University of Minnesota, MN, USA
Psychol Med 35:1133-44. 2005.... - Education and cognitive ability as direct, mediating, or spurious influences on female age at first birth: behavior genetic models fit to Danish twin dataJoseph Lee Rodgers
Department of Psychology, 455 West Lindsey Street, Room 809, University of Oklahoma, Norman, Oklahoma 73019, USA
AJS 114:S202-32. 2008..Second, even in a natural laboratory sensitive to genetic variance in female fertility -- during demographic transition -- the variance in AFB was non-genetic, located instead within the shared environment... - How are parent-child conflict and childhood externalizing symptoms related over time? Results from a genetically informative cross-lagged studyS Alexandra Burt
Department of Psychology, Michigan State University, Psychology Building, East Lansing, MI 48824, USA
Dev Psychopathol 17:145-65. 2005..These results suggest a "downward spiral" of interplay between parent-child conflict and EXT, and offer confirmation of a (partially) environmentally mediated effect of parenting on child behavior... - Disordered eating and substance use in an epidemiological sample: II. Associations within familiesKristin M von Ranson
Dept of Psychology, University of Minnesota Twin Cities Campus, Minneapolis, MN, USA
Psychol Addict Behav 17:193-201. 2003..These results suggest that these problems are not cross-transmitted within families and suggest that the addiction model of eating disorders may be simplistic... - The association of early adolescent problem behavior and adult psychopathology: a multivariate behavioral genetic perspectiveMatt McGue
Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
Behav Genet 36:591-602. 2006..60) and accounted for primarily by genetic factors common to the two domains. Findings are discussed in the context of research on the prevention and developmental nature of substance use disorders and related psychopathology... - Using latent trait modeling to conceptualize an alcohol problems continuumRobert F Krueger
Department of Psychology, University of Minnesota, Minneapolis, MN, USA
Psychol Assess 16:107-19. 2004..These results indicate that alcohol problems can be arrayed along a dimension of severity and emphasize the relevance of LTM to informing the conceptualization and assessment of alcohol problems... - Genetic and environmental contributions to the diversity of substances used in adolescent twins: a longitudinal study of age and sex effectsJaime Derringer
Department of Psychology, University of Minnesota, Minneapolis, MN, USA
Addiction 103:1744-51. 2008..To determine how genetic and environmental contributions affecting the number of psychoactive substances used varies with age and gender over the course of adolescence... - The effect of parental alcohol and drug disorders on adolescent personalityIrene J Elkins
Department of Psychiatry, University of Minnesota, Minneapolis, 55455, USA
Am J Psychiatry 161:670-6. 2004.... - Marriage and personality: a genetic analysisWendy Johnson
Department of Psychology, University of Minnesota, Twin Cities, Minneapolis, MN 55455, USA
J Pers Soc Psychol 86:285-94. 2004..The results suggest that propensity to marry is heritable and that the phenotypic link between personality and propensity to marry is genetically influenced... - Shared-environmental contributions to high cognitive abilityRobert M Kirkpatrick
Department of Psychology, University of Minnesota, Minneapolis, MN, USA
Behav Genet 39:406-16. 2009..We discuss these results in terms of the need for cognitive-development research to combine genetically sensitive designs and modern statistical methods with broad, thorough environmental measurement... - Environmental adversity and increasing genetic risk for externalizing disordersBrian M Hicks
Department of Psychology, University of Minnesota, 75 E River Rd, Minneapolis, MN 55455, USA
Arch Gen Psychiatry 66:640-8. 2009..However, few attempts have been made to integrate findings and to articulate general mechanisms of gene-environment influence in the emergence of psychopathology... - Are there shared environmental influences on adolescent behavior? Evidence from a study of adoptive siblingsJacob P Buchanan
Department of Psychology, University of Minnesota, 75 East River Rd, Minneapolis, MN, 55455, USA
Behav Genet 39:532-40. 2009..These findings support the use of adoptive sibling designs to directly estimate shared environmental effects and implicate the existence of systematic environmental influences on behavior that are potentially detectable... - The enrichment study of the Minnesota twin family study: increasing the yield of twin families at high risk for externalizing psychopathologyMargaret A Keyes
Department of Psychology, University of Minnesota, Minneapolis, MN 55455United States of America
Twin Res Hum Genet 12:489-501. 2009..At the pair level, 63% of the screened pairs had at least one member with a childhood disruptive disorder. This article provides an overview of the study design and includes a review of recent findings using this sample of twins... - Stability, change, and heritability of borderline personality disorder traits from adolescence to adulthood: a longitudinal twin studyMarina A Bornovalova
Department of Psychology, University of Minnesota, 75 East River Road, Minneapolis, MN 55455, USA
Dev Psychopathol 21:1335-53. 2009.... - Parent-child conflict and the comorbidity among childhood externalizing disordersS Alexandra Burt
Department of Psychology, University of Minnesota, Minneapolis 55455, USA
Arch Gen Psychiatry 60:505-13. 2003..Our goals were to determine whether parent-child conflict was associated with the comorbidity among ADHD, CD, and ODD, and to explicitly examine the etiology of this association via a genetically informative design... - Minnesota Twin Family StudyWilliam G Iacono
Minnesota Center for Twin and Family Research, Department of Psychology, University of Minnesota, Minneapolis 55455, USA
Twin Res 5:482-7. 2002..This article provides an overview of study methods, highlights published findings, and describes procedures in place to foster collaboration with other investigators... - Genetic and environmental influences on human psychological differencesThomas J Bouchard
Department of Psychology, University of Minnesota, Minneapolis, Minnesota 55455, USA
J Neurobiol 54:4-45. 2003..We conclude that there is now strong evidence that virtually all individual psychological differences, when reliably measured, are moderately to substantially heritable... - Mothers' maximum drinks ever consumed in 24 hours predicts mental health problems in adolescent offspringStephen M Malone
University of Minnesota, Minneapolis, MN 55455, USA
J Child Psychol Psychiatry 51:1067-75. 2010..The purpose of the present study was to determine whether maternal maximum consumption has similar correlates... - Etiologic connections among substance dependence, antisocial behavior, and personality: modeling the externalizing spectrumRobert F Krueger
Department of Psychology, University of Minnesota, Minneapolis 55455 0344, USA
J Abnorm Psychol 111:411-24. 2002..These results reconcile evidence for general and specific causal factors within the externalizing spectrum and offer the externalizing factor as a novel target for future research... - Identifying shared environmental contributions to early substance use: the respective roles of peers and parentsBrent Walden
Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
J Abnorm Psychol 113:440-50. 2004..Findings also indicated that peer deviance, but not parent-child relationship problems, accounted uniquely for variance in early substance use... - An adoption study of parental depression as an environmental liability for adolescent depression and childhood disruptive disordersERIN C TULLY
Department of Psychology, N218 Elliott Hall, University of Minnesota, 75 East River Rd, Minneapolis, MN 55455, USA
Am J Psychiatry 165:1148-54. 2008..The authors used an adoption study design to investigate environmental influences on risk for psychopathology in adolescents with depressed parents... - Etiological contributions to heavy drinking from late adolescence to young adulthoodSerena M King
Department of Psychology, University of Minnesota, Twin Cities, MN, USA
J Abnorm Psychol 114:587-98. 2005.... - Differential parent-child relationships and adolescent externalizing symptoms: cross-lagged analyses within a monozygotic twin differences designS Alexandra Burt
Department of Psychology, Michigan State University, East Lansing, MI 48824, USA
Dev Psychol 42:1289-98. 2006..These results suggest that markedly different parent-child conflict has an environmentally mediated impact on child behavior through mid-adolescence, findings that yield insights into environmental influences on behavior... - Perceptions of the parent-adolescent relationship: a longitudinal investigationMatt McGue
Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
Dev Psychol 41:971-84. 2005..Changes in the parent-child relationship are interpreted as reflecting genotype-environment correlation processes whereby adolescents increasingly influence their relationships with their parents... - Minnesota Center for Twin and Family ResearchWilliam G Iacono
Minnesota Center for Twin and Family Research, University of Minnesota Twin Cities Campus, 75 East River Road, Minneapolis, MN 55455, USA
Twin Res Hum Genet 9:978-84. 2006..Measurement of EEG and autonomic nervous system reactivity is also part of the assessment battery for twin families. This article provides an overview of study design and includes a review of recent MCTFR findings... - Symptom-based subfactors of DSM-defined conduct disorder: evidence for etiologic distinctionsJennifer L Tackett
Department of Psychology, University of Minnesota, Twin Cities Campus, Minneapolis, MN 55455, USA
J Abnorm Psychol 114:483-7. 2005..The authors discuss implications of these findings for the assessment and treatment of CD... - Religiousness, antisocial behavior, and altruism: genetic and environmental mediationLaura B Koenig
Department of Psychology, University of Minnesota, Minneapolis 55455, USA
J Pers 75:265-90. 2007..Altruistic behavior also shared most all of its genetic influence, but only half of its shared environmental influence, with religiousness... - Association between P3 event-related brain potential amplitude and adolescent problem behaviorWilliam G Iacono
Department of Psychology, University of Minnesota, Minneapolis, Minnesota 55455, USA
Psychophysiology 43:465-9. 2006..Our results suggest that reduced P3 may also be associated with early expression of behaviors that predict the development of these disorders... - Early onset problem behavior, young adult psychopathology, and contextual riskMargaret A Keyes
Department of Psychology, University of Minnesota, Minneapolis, Minnesota 55455, USA
Twin Res Hum Genet 10:45-53. 2007..The results are discussed in the context of emerging research on the prognostic significance of early adolescent problem behavior for risk of adult psychopathology... - Gender differences and developmental change in externalizing disorders from late adolescence to early adulthood: A longitudinal twin studyBrian M Hicks
University of Minnesota, Department of Psychology, Minneapolis, MN 55455, USA
J Abnorm Psychol 116:433-47. 2007..Results illustrate the importance of gender and developmental context for symptom expression and the utility of structural models to integrate general trends and disorder-specific characteristics... - Prospective effects of attention-deficit/hyperactivity disorder, conduct disorder, and sex on adolescent substance use and abuseIrene J Elkins
Department of Psychology, University of Minnesota, 75 E River Road, Minneapolis, MN 55455, USA
Arch Gen Psychiatry 64:1145-52. 2007..However, the ADHD-substance abuse relationship often disappears when co-occurring conduct disorder (CD) is considered... - Mendelian randomization: a novel test of the gateway hypothesis and models of gene-environment interplayDaniel E Irons
Department of Psychology, University of Minnesota, 75 East River Road, Minneapolis, MN 55455, USA
Dev Psychopathol 19:1181-95. 2007.... - Genetic and environmental influences on adolescents' perceptions of current family environmentRyan W Herndon
Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
Behav Genet 35:373-80. 2005..These findings support a genetic basis of perceptions of one's family environment and indicate that reports of control/structure may be more genetically influenced than previously believed based on retrospective reports... - Genetic and environmental influences on religiousness: findings for retrospective and current religiousness ratingsLaura B Koenig
Department of Psychology, University of Minnesota Twin Cities, Minneapolis, MN 55455, USA
J Pers 73:471-88. 2005..Analysis of internal and external religiousness subscales of the total score revealed similar results. These findings support the hypothesis that the heritability of religiousness increases from adolescence to adulthood... - Stability and change in religiousness during emerging adulthoodLaura B Koenig
Department of Psychology, University of Minnesota, USA
Dev Psychol 44:532-43. 2008..For the younger cohort, change was genetic in origin, while stability was environmental. In the older cohort, change was influenced by nonshared environment and stability by both genes and family environment... - Genetic and environmental influences on antisocial behavior and alcohol dependence from adolescence to early adulthoodStephen M Malone
Department of Psychology, University of Minnesota, Minneapolis, MN 55455, USA
Dev Psychopathol 16:943-66. 2004.... - Parental smoking and adolescent problem behavior: an adoption study of general and specific effectsMargaret Keyes
Department of Psychology, University of Minnesota, 75 East River Rd, Minneapolis, MN 55455, USA
Am J Psychiatry 165:1338-44. 2008..The purpose of this study was to examine the genetic and environmental contributions to the risk represented by exposure to parental smoking and to assess the specificity of that risk...