Jessina C McGregor

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi request reprint Utility of the Chronic Disease Score and Charlson Comorbidity Index as comorbidity measures for use in epidemiologic studies of antibiotic-resistant organisms
    Jessina C McGregor
    Department of Epidemiology and Preventive Medicine, School of Medicine, University of Maryland, Baltimore, MD 21201, USA
    Am J Epidemiol 161:483-93. 2005
  2. ncbi request reprint Comorbidity risk-adjustment measures were developed and validated for studies of antibiotic-resistant infections
    Jessina C McGregor
    Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, MD 21201, USA
    J Clin Epidemiol 59:1266-73. 2006
  3. pmc Impact of a computerized clinical decision support system on reducing inappropriate antimicrobial use: a randomized controlled trial
    Jessina C McGregor
    Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, 100 North Greene Street, Lower Level, Baltimore, MD 21201, USA
    J Am Med Inform Assoc 13:378-84. 2006
  4. pmc Impact of empiric antimicrobial therapy on outcomes in patients with Escherichia coli and Klebsiella pneumoniae bacteremia: a cohort study
    Kerri A Thom
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
    BMC Infect Dis 8:116. 2008
  5. ncbi request reprint Value of performing active surveillance cultures on intensive care unit discharge for detection of methicillin-resistant Staphylococcus aureus
    Jon P Furuno
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Infect Control Hosp Epidemiol 28:666-70. 2007
  6. pmc Clinical utility of infection control documentation of prior methicillin-resistant Staphylococcus aureus colonization or infection for optimization of empirical antibiotic therapy
    Marin L Schweizer
    Department of Epidemiology, University of Maryland School of Medicine, Baltimore, Maryland 2201, USA
    Infect Control Hosp Epidemiol 29:972-4. 2008
  7. pmc Risk of acquiring extended-spectrum β-lactamase-producing Klebsiella species and Escherichia coli from prior room occupants in the intensive care unit
    Adebola O Ajao
    Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA
    Infect Control Hosp Epidemiol 34:453-8. 2013
  8. pmc Comparative effectiveness of nafcillin or cefazolin versus vancomycin in methicillin-susceptible Staphylococcus aureus bacteremia
    Marin L Schweizer
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
    BMC Infect Dis 11:279. 2011
  9. pmc Controlling for severity of illness in outcome studies involving infectious diseases: impact of measurement at different time points
    Kerri A Thom
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Infect Control Hosp Epidemiol 29:1048-53. 2008
  10. pmc Empiric antibiotic therapy for Staphylococcus aureus bacteremia may not reduce in-hospital mortality: a retrospective cohort study
    Marin L Schweizer
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 5:e11432. 2010

Detail Information

Publications28

  1. ncbi request reprint Utility of the Chronic Disease Score and Charlson Comorbidity Index as comorbidity measures for use in epidemiologic studies of antibiotic-resistant organisms
    Jessina C McGregor
    Department of Epidemiology and Preventive Medicine, School of Medicine, University of Maryland, Baltimore, MD 21201, USA
    Am J Epidemiol 161:483-93. 2005
    ..05). A revised comorbidity measure specific to resistant infections would likely provide a better assessment of the comorbidity-attributable risk of antibiotic-resistant infections...
  2. ncbi request reprint Comorbidity risk-adjustment measures were developed and validated for studies of antibiotic-resistant infections
    Jessina C McGregor
    Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, MD 21201, USA
    J Clin Epidemiol 59:1266-73. 2006
    ....
  3. pmc Impact of a computerized clinical decision support system on reducing inappropriate antimicrobial use: a randomized controlled trial
    Jessina C McGregor
    Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, 100 North Greene Street, Lower Level, Baltimore, MD 21201, USA
    J Am Med Inform Assoc 13:378-84. 2006
    ..However, most function with minimal computer support. We evaluated the effectiveness and cost-effectiveness of a computerized clinical decision support system for the management of antimicrobial utilization...
  4. pmc Impact of empiric antimicrobial therapy on outcomes in patients with Escherichia coli and Klebsiella pneumoniae bacteremia: a cohort study
    Kerri A Thom
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
    BMC Infect Dis 8:116. 2008
    ....
  5. ncbi request reprint Value of performing active surveillance cultures on intensive care unit discharge for detection of methicillin-resistant Staphylococcus aureus
    Jon P Furuno
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Infect Control Hosp Epidemiol 28:666-70. 2007
    ..To quantify the value of performing active surveillance cultures for detection of methicillin-resistant Staphylococcus aureus (MRSA) on intensive care unit (ICU) discharge...
  6. pmc Clinical utility of infection control documentation of prior methicillin-resistant Staphylococcus aureus colonization or infection for optimization of empirical antibiotic therapy
    Marin L Schweizer
    Department of Epidemiology, University of Maryland School of Medicine, Baltimore, Maryland 2201, USA
    Infect Control Hosp Epidemiol 29:972-4. 2008
    ..Documented prior MRSA colonization or infection was predictive of subsequent MRSA infections (odds ratio, 4.05). Physicians appear to use this documentation when prescribing empirical therapy for suspected bacteremia...
  7. pmc Risk of acquiring extended-spectrum β-lactamase-producing Klebsiella species and Escherichia coli from prior room occupants in the intensive care unit
    Adebola O Ajao
    Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA
    Infect Control Hosp Epidemiol 34:453-8. 2013
    ..Intensifying environmental decontamination may be less effective than other interventions in preventing transmission of ESBL-producing pathogens...
  8. pmc Comparative effectiveness of nafcillin or cefazolin versus vancomycin in methicillin-susceptible Staphylococcus aureus bacteremia
    Marin L Schweizer
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
    BMC Infect Dis 11:279. 2011
    ..The outcome of interest for this study was 30-day in-hospital mortality...
  9. pmc Controlling for severity of illness in outcome studies involving infectious diseases: impact of measurement at different time points
    Kerri A Thom
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Infect Control Hosp Epidemiol 29:1048-53. 2008
    ..Severity of illness is an important confounder in outcome studies involving infectious diseases. However, it is unclear whether the time at which severity of illness is measured is important...
  10. pmc Empiric antibiotic therapy for Staphylococcus aureus bacteremia may not reduce in-hospital mortality: a retrospective cohort study
    Marin L Schweizer
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
    PLoS ONE 5:e11432. 2010
    ..We aimed to measure the clinical impact of appropriate empiric antibiotic therapy on mortality, while statistically adjusting for comorbidities, severity of illness and presence of virulence factors in the infecting strain...
  11. ncbi request reprint Identifying groups at high risk for carriage of antibiotic-resistant bacteria
    Jon P Furuno
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore 21201, USA
    Arch Intern Med 166:580-5. 2006
    ..We aimed to develop a highly sensitive, simple-to-administer prediction rule to identify subpopulations of patients at high risk for colonization on hospital admission...
  12. pmc Methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococci co-colonization
    Jon P Furuno
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Emerg Infect Dis 11:1539-44. 2005
    ..06, 95% CI 1.85-5.07). None of the co-colonized patients would have been identified with clinical cultures alone. We report a high prevalence of VRE/MRSA co-colonization upon admission to ICUs at a tertiary-care hospital...
  13. pmc Risk factors for colonization with extended-spectrum beta-lactamase-producing bacteria and intensive care unit admission
    Anthony D Harris
    Department of Epidemiology and Preventive Medicine, School of Medicine, University of Maryland, Baltimore 21201, USA
    Emerg Infect Dis 13:1144-9. 2007
    ..15; 95% CI 1.04-1.27). Coexisting conditions and previous antimicrobial drug exposure are thus predictive of colonization, and a large percentage of these patients have subsequent positive clinical cultures for ESBL-producing bacteria...
  14. pmc Risk factors for development of intestinal colonization with imipenem-resistant Pseudomonas aeruginosa in the intensive care unit setting
    Anthony D Harris
    Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Infect Control Hosp Epidemiol 32:719-22. 2011
    ..The aim of this study was to quantify potential risk factors for the development of IRPA not due to patient-to-patient transmission...
  15. ncbi request reprint Summer Peaks in the Incidences of Gram-Negative Bacterial Infection Among Hospitalized Patients
    Eli N Perencevich
    Veterans Affairs Maryland Health Care System, and the Department of Epidemiology and Preventive Medicine, University of MarylandSchool of Medicine, Baltimore, Maryland 21202, USA
    Infect Control Hosp Epidemiol 29:1124-31. 2008
    ..We quantified the seasonal variation in the incidences of hospital infection caused by common bacterial pathogens and estimated the association between temperature changes and infection rates...
  16. ncbi request reprint Prediction rules to identify patients with methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci upon hospital admission
    Jon P Furuno
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, 100 N Greene Street, Baltimore, MD 21201, USA
    Am J Infect Control 32:436-40. 2004
    ..The aim of this study was to assess the validity of factors from past medical history in defining patients at high risk for subsequent positive cultures with VRE or MRSA upon hospital admission...
  17. ncbi request reprint Relative influence of antibiotic therapy attributes on physician choice in treating acute uncomplicated pyelonephritis
    Jessina C McGregor
    Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, USA
    Med Decis Making 27:387-94. 2007
    ....
  18. pmc A nationwide analysis of antibiotic use in hospice care in the final week of life
    Jennifer S Albrecht
    Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Pain Symptom Manage 46:483-90. 2013
    ..Antibiotic prescription in hospice patients is complicated by the focus on palliative rather than curative care and concerns regarding increasing antibiotic resistance...
  19. pmc Economics of infection control surveillance technology: cost-effective or just cost?
    Jon P Furuno
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
    Am J Infect Control 36:S12-7. 2008
    ..However, little is known about the cost-effectiveness of these tools...
  20. doi request reprint The importance of case-mix adjustment for infection rates and the need for more research
    Anthony D Harris
    Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, Maryland 21201, USA
    Infect Control Hosp Epidemiol 29:693-4. 2008
  21. pmc The use and interpretation of quasi-experimental studies in medical informatics
    Anthony D Harris
    Division of Healthcare Outcomes Research, Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, 100 N Greene Street, Lower Level, Baltimore, MD, USA
    J Am Med Inform Assoc 13:16-23. 2006
    ..They hope that future medical informatics studies will implement higher level quasi-experimental study designs that yield more convincing evidence for causal links between medical informatics interventions and outcomes...
  22. ncbi request reprint Population antibiotic susceptibility for Streptococcus pneumoniae and treatment outcomes in common respiratory tract infections
    Jon P Furuno
    Department of Epidemiology and Preventive Medicine, University of Maryland, School of Medicine, Baltimore, MD 21201, USA
    Pharmacoepidemiol Drug Saf 15:1-9. 2006
    ..pneumoniae are associated with higher risk of treatment failure in suppurative acute otitis media (AOM), acute sinusitis, and acute exacerbation of chronic bronchitis (AECB)...
  23. pmc Impact of empiric antibiotic therapy on outcomes in patients with Pseudomonas aeruginosa bacteremia
    Regina B Osih
    University of Maryland, Department of Epidemiology and Preventive Medicine, 100 N Greene St lower level, Baltimore, MD 21201, USA
    Antimicrob Agents Chemother 51:839-44. 2007
    ..74). These data suggest that the use of appropriate empirical therapy, i.e., before susceptibility results are known may not be as critical to patient outcomes as other studies have suggested...
  24. pmc Quality of hospice care for individuals with dementia
    Jennifer S Albrecht
    Department of Pharmaceutical Health Services Research, School of Pharmacy, University of Maryland, Baltimore, Maryland 21201, USA
    J Am Geriatr Soc 61:1060-5. 2013
    ..The aim of this study was to quantify differences in quality of care measures between hospice patients with and without dementia...
  25. ncbi request reprint What infection control interventions should be undertaken to control multidrug-resistant gram-negative bacteria?
    Anthony D Harris
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Clin Infect Dis 43:S57-61. 2006
    ....
  26. pmc Clinical prediction tool to identify patients with Pseudomonas aeruginosa respiratory tract infections at greatest risk for multidrug resistance
    Thomas P Lodise
    Albany College of Pharmacy, Department of Pharmacy Practice, and Department of Pharmacy, Albany Medical Center Hospital, 106 New Scotland Avenue, Albany, NY 12208 3492, USA
    Antimicrob Agents Chemother 51:417-22. 2007
    ..aeruginosa respiratory tract infections at our institution. Identifying these risk factors enabled us to develop a prediction tool to assess the risk of resistance and thus guide empirical antibiotic therapy...
  27. pmc Predictors of 30-day mortality among patients with Pseudomonas aeruginosa bloodstream infections: impact of delayed appropriate antibiotic selection
    Thomas P Lodise
    Albany College of Pharmacy, Pharmacy Practice, Albany College of Pharmacy, Albany, NY 12208 3492, USA
    Antimicrob Agents Chemother 51:3510-5. 2007
    ..The data strongly suggest that delaying appropriate therapy for approximately 2 days significantly increases the risk of 30-day mortality in patients with P. aeruginosa bloodstream infections...
  28. ncbi request reprint A systematic review of the methods used to assess the association between appropriate antibiotic therapy and mortality in bacteremic patients
    Jessina C McGregor
    Oregon State University College of Pharmacy, Portland, OR 97239, USA
    Clin Infect Dis 45:329-37. 2007
    ..In brief, future studies should define "inappropriate" therapy on the basis of in vitro susceptibility data, should separately evaluate empiric and definitive therapy, and should control for the baseline severity of illness...