Mary M McGrane

Summary

Affiliation: University of Connecticut
Country: USA

Publications

  1. ncbi Vitamin A regulation of gene expression: molecular mechanism of a prototype gene
    Mary M McGrane
    Department of Nutritional Sciences, The University of Connecticut, Storrs, CT 06269, USA
    J Nutr Biochem 18:497-508. 2007
  2. pmc Effects of increased dietary cholesterol with carbohydrate restriction on hepatic lipid metabolism in Guinea pigs
    Ryan DeOgburn
    Department of Nutritional Sciences, University of Connecticut, Storrs, Connecticut, USA
    Comp Med 62:109-15. 2012
  3. doi Low-carbohydrate diets reduce lipid accumulation and arterial inflammation in guinea pigs fed a high-cholesterol diet
    Jose O Leite
    Department of Nutritional Sciences, University of Connecticut, Storrs, CT 06269, USA
    Atherosclerosis 209:442-8. 2010
  4. ncbi Vitamin A status in mice affects the histone code of the phosphoenolpyruvate carboxykinase gene in liver
    Kelly B Scribner
    Departments of Nutritional Sciences and Molecular and Cellular Biology, The University of Connecticut, Storrs, CT 06269, USA
    J Nutr 135:2774-9. 2005
  5. ncbi Nuclear receptor binding to the retinoic acid response elements of the phosphoenolpyruvate carboxykinase gene in vivo: effects of vitamin A deficiency
    Kelly B Scribner
    Department of Nutritional Sciences, The University of Connecticut, Storrs, CT 06269, USA
    J Nutr Biochem 18:206-14. 2007
  6. ncbi RNA polymerase II association with the phosphoenolpyruvate carboxykinase (PEPCK) promoter is reduced in vitamin A-deficient mice
    Kelly B Scribner
    Department of Nutritional Sciences, The University of Connecticut, Storrs, CT 06269, USA
    J Nutr 133:4112-7. 2003
  7. ncbi Vitamin A depletion is associated with low phosphoenolpyruvate carboxykinase mRNA levels during late fetal development and at birth in mice
    Saheli Ghoshal
    Department of Nutritional Sciences and Molecular and Cell Biology, University of Connecticut, Storrs, CT 06269, USA
    J Nutr 133:2131-6. 2003
  8. ncbi Altered lipid catabolism in the vitamin A deficient liver
    Hye Won Kang
    Departments of Nutritional Sciences and Molecular and Cellular Biology, The University of Connecticut, 3624 Horsebarn Hill Road Extension, Storrs, CT 06269, USA
    Mol Cell Endocrinol 271:18-27. 2007
  9. doi Raisins and walking alter appetite hormones and plasma lipids by modifications in lipoprotein metabolism and up-regulation of the low-density lipoprotein receptor
    Michael J Puglisi
    Department of Nutritional Sciences, University of Connecticut, Storrs, CT 06269, USA
    Metabolism 58:120-8. 2009
  10. pmc Carbohydrate restriction and dietary cholesterol modulate the expression of HMG-CoA reductase and the LDL receptor in mononuclear cells from adult men
    Gisella Mutungi
    Department of Nutritional Sciences, University of Connecticut, Storrs, CT, 06269 USA
    Lipids Health Dis 6:34. 2007

Collaborators

Detail Information

Publications13

  1. ncbi Vitamin A regulation of gene expression: molecular mechanism of a prototype gene
    Mary M McGrane
    Department of Nutritional Sciences, The University of Connecticut, Storrs, CT 06269, USA
    J Nutr Biochem 18:497-508. 2007
    ....
  2. pmc Effects of increased dietary cholesterol with carbohydrate restriction on hepatic lipid metabolism in Guinea pigs
    Ryan DeOgburn
    Department of Nutritional Sciences, University of Connecticut, Storrs, Connecticut, USA
    Comp Med 62:109-15. 2012
    ..LCD livers had more proliferating hepatocytes than did HCD livers, suggesting that in the context of cholesterol-induced hepatic steatosis, dietary carbohydrate restriction enhances liver cell proliferation...
  3. doi Low-carbohydrate diets reduce lipid accumulation and arterial inflammation in guinea pigs fed a high-cholesterol diet
    Jose O Leite
    Department of Nutritional Sciences, University of Connecticut, Storrs, CT 06269, USA
    Atherosclerosis 209:442-8. 2010
    ..Low-carbohydrate diets (LCD) efficiently induce weight loss and favorably affect plasma lipids, however, the effect of LCD on atherosclerosis is still argued...
  4. ncbi Vitamin A status in mice affects the histone code of the phosphoenolpyruvate carboxykinase gene in liver
    Kelly B Scribner
    Departments of Nutritional Sciences and Molecular and Cellular Biology, The University of Connecticut, Storrs, CT 06269, USA
    J Nutr 135:2774-9. 2005
    ..These results demonstrate the associated changes that occur in nuclear receptor binding, coactivator recruitment, and histone acetylation in response to vitamin A status, identified at specific RAREs in the PEPCK gene in vivo...
  5. ncbi Nuclear receptor binding to the retinoic acid response elements of the phosphoenolpyruvate carboxykinase gene in vivo: effects of vitamin A deficiency
    Kelly B Scribner
    Department of Nutritional Sciences, The University of Connecticut, Storrs, CT 06269, USA
    J Nutr Biochem 18:206-14. 2007
    ....
  6. ncbi RNA polymerase II association with the phosphoenolpyruvate carboxykinase (PEPCK) promoter is reduced in vitamin A-deficient mice
    Kelly B Scribner
    Department of Nutritional Sciences, The University of Connecticut, Storrs, CT 06269, USA
    J Nutr 133:4112-7. 2003
    ..These results increase our understanding of the molecular basis for decreased PEPCK gene expression in VAD mice in vivo and offer additional insight into the regulation of other retinoid-responsive genes...
  7. ncbi Vitamin A depletion is associated with low phosphoenolpyruvate carboxykinase mRNA levels during late fetal development and at birth in mice
    Saheli Ghoshal
    Department of Nutritional Sciences and Molecular and Cell Biology, University of Connecticut, Storrs, CT 06269, USA
    J Nutr 133:2131-6. 2003
    ..Our findings strongly suggest that vitamin A is required during liver development for staged expression of the PEPCK gene and that HNF4alpha may be involved in mediating vitamin A regulation of the PEPCK gene at these critical periods...
  8. ncbi Altered lipid catabolism in the vitamin A deficient liver
    Hye Won Kang
    Departments of Nutritional Sciences and Molecular and Cellular Biology, The University of Connecticut, 3624 Horsebarn Hill Road Extension, Storrs, CT 06269, USA
    Mol Cell Endocrinol 271:18-27. 2007
    ..Down regulation of the PPAR alpha gene is the likely cause of the altered expression pattern of the above metabolic genes in VAD liver...
  9. doi Raisins and walking alter appetite hormones and plasma lipids by modifications in lipoprotein metabolism and up-regulation of the low-density lipoprotein receptor
    Michael J Puglisi
    Department of Nutritional Sciences, University of Connecticut, Storrs, CT 06269, USA
    Metabolism 58:120-8. 2009
    ..These data suggest that walking and raisin consumption decrease plasma LDL cholesterol by up-regulating the LDL receptor and that raisin consumption may reduce hunger and affect dietary intake by altering hormones influencing satiety...
  10. pmc Carbohydrate restriction and dietary cholesterol modulate the expression of HMG-CoA reductase and the LDL receptor in mononuclear cells from adult men
    Gisella Mutungi
    Department of Nutritional Sciences, University of Connecticut, Storrs, CT, 06269 USA
    Lipids Health Dis 6:34. 2007
    ..00 +/- 0.60 to 1.67 +/- 1.94 arbitrary units P < 0.05). The findings indicate that dietary cholesterol during a weight loss intervention alters the expression of genes regulating cholesterol homeostasis...
  11. ncbi Retinoid regulation of the phosphoenolpyruvate carboxykinase gene in liver
    Dong Ju Shin
    Departments of Nutritional Sciences and Molecular and Cell Biology, The University of Connecticut, Storrs, CT 06269, USA
    Mol Cell Endocrinol 195:39-54. 2002
    ..The binding of nuclear receptors to PEPCK RARE1, RARE2 and RARE3 indicates a complex pattern of retinoid receptor and orphan nuclear receptor binding...
  12. doi Low-carbohydrate diet disrupts the association between insulin resistance and weight gain
    Jose O Leite
    Department of Nutritional Sciences, University of Connecticut, Storrs, CT 06269, USA
    Metabolism 58:1116-22. 2009
    ..The association between weight gain and insulin resistance seems to be dependent on high carbohydrate intake...
  13. ncbi A combination of psyllium and plant sterols alters lipoprotein metabolism in hypercholesterolemic subjects by modifying the intravascular processing of lipoproteins and increasing LDL uptake
    Sudeep Shrestha
    Department of Nutritional Sciences, University of Connecticut, Storrs, CT 06269, USA
    J Nutr 137:1165-70. 2007
    ..03). These results indicate that the hypocholesterolemic action of PSY and PS can be explained in part by modifications in the intravascular processing of lipoproteins and by increases in LDL receptor-mediated uptake...