Research Topics
Species | R C McGlennenSummaryAffiliation: University of Minnesota Country: USA Publications
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Detail Information
Publications
Clinical and laboratory management of the prothrombin G20210A mutationRonald C McGlennen
Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, USA
Arch Pathol Lab Med 126:1319-25. 2002..DAT SOURCES: Review of the medical literature, primarily since 1996...
Human papillomavirus oncogenesisR C McGlennen
Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, USA
Clin Lab Med 20:383-406. 2000..By in large, the nononcogenic viruses do not effect irreversible growth properties through these same viral genes and the same cellular counterparts...
Miniaturization technologies for molecular diagnosticsR C McGlennen
Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, 420 Delaware St SE, Minneapolis, MN 55455, USA
Clin Chem 47:393-402. 2001..The purpose of this review is to highlight the underlying principles in miniaturization, the strategies being developed for bioanalysis, and the potential impact on the practice of this rapidly growing medical discipline...
Are benign cellular changes on a Papanicolaou smear really benign? A prospective cohort studyK L Margolis
Department of Medicine, Hennepin County Medical Center, USA
Arch Fam Med 8:433-9. 1999....
bcl-1 gene rearrangements in mantle cell lymphoma: a comprehensive analysis of 118 cases, including B-5-fixed tissue, by polymerase chain reaction and Southern transfer analysisR Chibbar
Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, USA
Mod Pathol 11:1089-97. 1998..The results obtained from these tissues are comparable to those obtained from frozen or formalin-fixed tissue...
Simultaneous allele-specific amplification: a strategy using modified primer-template mismatches for SNP detection--application to prothrombin 20210A (factor II) and factor V Leiden (1691A) gene mutationsS A DelRio-LaFreniere
University of Minnesota, Minneapolis, MN, USA
Mol Diagn 6:201-9. 2001..CONCLUSION: The simultaneous allele-specific amplification method allows simultaneous detection of wild-type and mutant alleles by PCR using four distinct primers. Nucleotide mismatches in the primers reduce competitive amplification...
Dynamic mutations pose unique challenges for the molecular diagnostics laboratoryR C McGlennen
Department of Laboratory Medicine and Pathology, University of Minnesota Health System, Minneapolis 55455, USA
Clin Chem 42:1582-8. 1996....
Leukemia in donor cells after allogeneic hematopoietic stem cell transplantC G Brunstein
Division of Hematology, Oncology and Transplantation, Department of Medicine University of Minnesota, Minneapolis, MN 55455, USA
Bone Marrow Transplant 29:999-1003. 2002..5 years after related donor HSCT for refractory chronic lymphocytic leukemia and therapy-induced myelodysplastic syndrome. The origin of the leukemia was determined by analysis of minisatillite polymorphism tested on CD34(+) cells...
Low-density addressable array for the detection and typing of the human papillomavirusSusie A Delrio-Lafreniere
Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN, USA
Diagn Microbiol Infect Dis 48:23-31. 2004....
Hyperhomocyst(e)inemia and ThrombophiliaNigel S Key
Department of Medicine, Division of Hematology, Oncology, and Transplantation, University of Minnesota, Minneapolis 55455, USA
Arch Pathol Lab Med 126:1367-75. 2002..To review the role of an elevated total plasma homocysteine level (hyperhomocyst[e]inemia) in patients with venous or arterial thrombosis, as reflected by the medical literature and the consensus opinion of recognized experts in the field...
MLL amplification in myeloid malignancies: clinical, molecular, and cytogenetic findingsMichelle Dolan
Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN, USA
Cancer Genet Cytogenet 134:93-101. 2002..Additionally, we summarize the salient clinical, cytogenetic and molecular findings of the 29 other cases of MLL amplification that have thus far been reported...
Protein self-organization patterns in dried serum reveal changes in B-cell disordersAnthony A Killeen
Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota 55455, USA
Mol Diagn Ther 10:371-80. 2006..Since many individuals with elevated immunoglobulin have no symptoms, it is important to have simple methods for initial screening of patients with suspected B-cell disorders...
The molecular characterization of fatal infectious mononucleosisMyra J Wick
Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis 55455, USA
Am J Clin Pathol 117:582-8. 2002..In contrast, patients with nonfatal IM may lack monoclonal EBV and monoclonal rearrangements of the aforementioned genes. The reasons EBV induces a monoclonal proliferation only in some patients remain to be elucidated...
The diagnosis of Trichomonas vaginalis in liquid-based Pap tests: correlation with PCRDeniz L Aslan
Department of Pathology and Laboratory Medicine, University of Minnesota, Minneapolis, Minnesota 55455, USA
Diagn Cytopathol 32:341-4. 2005..PCR confirmed the presence of T. vaginalis in 50 of 51 (98%) LBP and identified 2 additional cases. Morphologic identification of T. vaginalis on LBP is highly accurate and should not require confirmatory testing...
