Edward O McFalls

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. pmc Outcomes of hospitalized patients with non-acute coronary syndrome and elevated cardiac troponin level
    Edward O McFalls
    Cardiology Section, Veterans Affairs Medical Center, Minneapolis, Minn 55417, USA
    Am J Med 124:630-5. 2011
  2. doi Prognostic value of 12-lead electrocardiogram and peak troponin I level after vascular surgery
    Santiago Garcia
    Department of Medicine, Division of Cardiology, Minneapolis VA Medical Center and University of Minnesota, Minneapolis, MN 55417, USA
    J Vasc Surg 57:166-72. 2013
  3. doi Diagnostic coronary angiography in patients with peripheral arterial disease: a sub-study of the Coronary Artery Revascularization Prophylaxis Trial
    Santiago Garcia
    Minneapolis Veterans Affairs Medical Center and the University of Minnesota, Minneapolis, MN 55417, USA
    J Interv Cardiol 21:369-74. 2008
  4. doi Preoperative coronary artery revascularization and long-term outcomes following abdominal aortic vascular surgery in patients with abnormal myocardial perfusion scans: a subgroup analysis of the coronary artery revascularization prophylaxis trial
    Santiago Garcia
    Minneapolis VA Medical Center and University of Minnesota, Department of Medicine, Division of Cardiology, Minneapolis, Minnesota, USA
    Catheter Cardiovasc Interv 77:134-41. 2011
  5. doi Culprit coronary lesions requiring percutaneous coronary intervention after vascular surgery often arise from in-stent restenosis of bare metal stents
    Santiago Garcia
    Division of Cardiology, University of Minnesota and Minneapolis VA Medical Center, Minneapolis, MN 55417, USA
    Ann Vasc Surg 24:596-601. 2010
  6. doi Perioperative complications after vascular surgery are predicted by the revised cardiac risk index but are not reduced in high-risk subsets with preoperative revascularization
    Santiago Garcia
    Division of Cardiology, Minneapolis VA Medical Center and the University of Minnesota, Minneapolis, Minn, USA
    Circ Cardiovasc Qual Outcomes 2:73-7. 2009
  7. pmc Altered expression of mitochondrial electron transport chain proteins and improved myocardial energetic state during late ischemic preconditioning
    Jesus A Cabrera
    Cardiology and Cardiothoracic Surgery Sections, VA Medical Center, University of Minnesota, Minneapolis, MN 55417, USA
    Am J Physiol Heart Circ Physiol 302:H1974-82. 2012
  8. doi Reduced expression of mitochondrial electron transport chain proteins from hibernating hearts relative to ischemic preconditioned hearts in the second window of protection
    Jesus A Cabrera
    Cardiology and Cardiothoracic Surgery Sections, VA Medical Center and University of Minnesota, Minneapolis, MN 55417, USA
    J Mol Cell Cardiol 60:90-6. 2013
  9. pmc Utility of nuclear stress imaging for detecting coronary artery bypass graft disease
    Basel Al Aloul
    University of Minnesota, Minneapolis, MN, USA
    BMC Cardiovasc Disord 12:62. 2012
  10. doi Peak postoperative troponin levels outperform preoperative cardiac risk indices as predictors of long-term mortality after vascular surgery Troponins and postoperative outcomes
    Nicholas Marston
    Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, MN 55417, USA
    J Crit Care 27:66-72. 2012

Detail Information

Publications31

  1. pmc Outcomes of hospitalized patients with non-acute coronary syndrome and elevated cardiac troponin level
    Edward O McFalls
    Cardiology Section, Veterans Affairs Medical Center, Minneapolis, Minn 55417, USA
    Am J Med 124:630-5. 2011
    ..Although cardiac troponin levels may be elevated in patients presenting with non-acute coronary syndrome conditions, specific diagnoses and long-term outcomes within that cohort are unclear...
  2. doi Prognostic value of 12-lead electrocardiogram and peak troponin I level after vascular surgery
    Santiago Garcia
    Department of Medicine, Division of Cardiology, Minneapolis VA Medical Center and University of Minnesota, Minneapolis, MN 55417, USA
    J Vasc Surg 57:166-72. 2013
    ....
  3. doi Diagnostic coronary angiography in patients with peripheral arterial disease: a sub-study of the Coronary Artery Revascularization Prophylaxis Trial
    Santiago Garcia
    Minneapolis Veterans Affairs Medical Center and the University of Minnesota, Minneapolis, MN 55417, USA
    J Interv Cardiol 21:369-74. 2008
    ..The goal of this sub-study of the Coronary Artery Revascularization Prophylaxis (CARP) trial was to assess the safety of coronary angiography in patients with peripheral vascular disease...
  4. doi Preoperative coronary artery revascularization and long-term outcomes following abdominal aortic vascular surgery in patients with abnormal myocardial perfusion scans: a subgroup analysis of the coronary artery revascularization prophylaxis trial
    Santiago Garcia
    Minneapolis VA Medical Center and University of Minnesota, Department of Medicine, Division of Cardiology, Minneapolis, Minnesota, USA
    Catheter Cardiovasc Interv 77:134-41. 2011
    ....
  5. doi Culprit coronary lesions requiring percutaneous coronary intervention after vascular surgery often arise from in-stent restenosis of bare metal stents
    Santiago Garcia
    Division of Cardiology, University of Minnesota and Minneapolis VA Medical Center, Minneapolis, MN 55417, USA
    Ann Vasc Surg 24:596-601. 2010
    ....
  6. doi Perioperative complications after vascular surgery are predicted by the revised cardiac risk index but are not reduced in high-risk subsets with preoperative revascularization
    Santiago Garcia
    Division of Cardiology, Minneapolis VA Medical Center and the University of Minnesota, Minneapolis, Minn, USA
    Circ Cardiovasc Qual Outcomes 2:73-7. 2009
    ..Among patients with documented coronary artery disease who undergo vascular surgery, it is unclear whether preoperative revascularization reduces postoperative cardiac complications in high-risk subsets defined by the RCRI...
  7. pmc Altered expression of mitochondrial electron transport chain proteins and improved myocardial energetic state during late ischemic preconditioning
    Jesus A Cabrera
    Cardiology and Cardiothoracic Surgery Sections, VA Medical Center, University of Minnesota, Minneapolis, MN 55417, USA
    Am J Physiol Heart Circ Physiol 302:H1974-82. 2012
    ..These data support the notion that mitochondrial adaptations that may reduce oxidant damage do not reduce the overall efficiency of energetics during sustained oxygen deprivation...
  8. doi Reduced expression of mitochondrial electron transport chain proteins from hibernating hearts relative to ischemic preconditioned hearts in the second window of protection
    Jesus A Cabrera
    Cardiology and Cardiothoracic Surgery Sections, VA Medical Center and University of Minnesota, Minneapolis, MN 55417, USA
    J Mol Cell Cardiol 60:90-6. 2013
    ..These data support the concept that HIB heart tissue subjected to chronically reduced blood flow is associated with a down-regulation in the expression of key mitochondrial proteins involved in electron transport...
  9. pmc Utility of nuclear stress imaging for detecting coronary artery bypass graft disease
    Basel Al Aloul
    University of Minnesota, Minneapolis, MN, USA
    BMC Cardiovasc Disord 12:62. 2012
    ..The value of single photon emission computed tomography stress myocardial perfusion imaging (SPECT-MPI) for detecting graft disease after coronary artery bypass surgery (CABG) has not been studied prospectively in an unselected cohort...
  10. doi Peak postoperative troponin levels outperform preoperative cardiac risk indices as predictors of long-term mortality after vascular surgery Troponins and postoperative outcomes
    Nicholas Marston
    Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, MN 55417, USA
    J Crit Care 27:66-72. 2012
    ..The utility of postoperative troponins as an independent predictor of long-term mortality after vascular surgery is unknown...
  11. doi Usefulness of revascularization of patients with multivessel coronary artery disease before elective vascular surgery for abdominal aortic and peripheral occlusive disease
    Santiago Garcia
    Cardiology Section, Veterans Affairs Medical Center, University of Minnesota, Minneapolis, Minnesota, USA
    Am J Cardiol 102:809-13. 2008
    ..6% of patients who underwent coronary angiography before vascular surgery, and this was the only subset of patients showing a benefit with preoperative coronary artery revascularization...
  12. doi Preoperative pulmonary function and mortality after cardiac surgery
    A Selcuk Adabag
    Division of Cardiology, Veterans Affairs Medical Center and University of Minnesota, Minneapolis, MN, USA
    Am Heart J 159:691-7. 2010
    ..The aim of the study was to examine the relationship between preoperative pulmonary function and outcomes after cardiac surgery...
  13. pmc Uncoupling protein-2 expression and effects on mitochondrial membrane potential and oxidant stress in heart tissue
    Jesus A Cabrera
    Department of Cardiology and Cardiac Surgery Sections, VA Medical Center, University of Minnesota, Minneapolis, MN 55417, USA
    Transl Res 159:383-90. 2012
    ..Thus, UCP-2 expression affords resistance to brief anoxia-reoxygenation...
  14. pmc Dose dependent effect of statins on postoperative atrial fibrillation after cardiac surgery among patients treated with beta blockers
    Salima Mithani
    Department of Internal Medicine, Veterans Affairs Medical Center, Veterans Drive, Minneapolis 55417, USA
    J Cardiothorac Surg 4:61. 2009
    ..Whether statins prevent AF in patients treated with postoperative beta blockers and whether the statin-effect is dose related are unknown...
  15. doi Continued depression of maximal oxygen consumption and mitochondrial proteomic expression despite successful coronary artery bypass grafting in a swine model of hibernation
    Rosemary F Kelly
    Department of Surgery, University of Minnesota, Minneapolis, Minn 55417, USA
    J Thorac Cardiovasc Surg 141:261-8. 2011
    ..We hypothesized that persistent contractile abnormalities after coronary artery bypass grafting are associated with decreased mitochondrial proteins involving electron transport chain that might limit maximal oxygen consumption...
  16. ncbi Activation of p38 MAPK and increased glucose transport in chronic hibernating swine myocardium
    Edward O McFalls
    Division of Cardiology, Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
    Am J Physiol Heart Circ Physiol 287:H1328-34. 2004
    ..As in preconditioned myocardium, activation of p38 MAPK may play an important role in the metabolic adaptations that characterize chronic hibernating myocardium...
  17. ncbi Mitochondrial function: the heart of myocardial preservation
    Edward O McFalls
    Department of Medicine, Veterans Affairs Medicial Center, University of Minnesota, Minneapolis, 55417, USA
    J Lab Clin Med 142:141-8. 2003
    ..It will also provide insight into the mechanisms by which mitochondrial signaling in preconditioning can protect the myocyte during subsequent prolonged ischemic periods...
  18. ncbi Myocardial glucose uptake after dobutamine stress in chronic hibernating swine myocardium
    Edward O McFalls
    Cardiology 111C, VA Medical Center, One Veterans Drive, Minneapolis, MN 55417, USA
    J Nucl Cardiol 10:385-94. 2003
    ....
  19. ncbi Repetitive supply-demand ischemia with dobutamine increases glucose uptake in postischemic and remote myocardium
    Edward O McFalls
    Department of Medicine, VA Medical Center, University of Minnesota, Minneapolis, Minnesota, USA
    J Nucl Med 44:85-91. 2003
    ..This would make it difficult to discriminate postischemic from remote myocardium with glucose tracers...
  20. ncbi Disparate opinions regarding indications for coronary artery revascularization before elective vascular surgery
    Gordon L Pierpont
    Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
    Am J Cardiol 94:1124-8. 2004
    ..Deviations from published guidelines are common, suggesting that current consensus statements need additional data to support their recommendations...
  21. ncbi Coronary artery bypass grafting is superior to percutaneous coronary intervention in prevention of perioperative myocardial infarctions during subsequent vascular surgery
    Herbert B Ward
    Department of Surgery, VA Medical Center and University of Minnesota, Minneapolis, Minnesota 55417, USA
    Ann Thorac Surg 82:795-800; discussion 800-1. 2006
    ..We hypothesized that more complete revascularization would improve outcomes after vascular surgery...
  22. ncbi Prognostic significance of elevated cardiac troponin I after heart surgery
    A Selcuk Adabag
    Division of Cardiology, Veterans Affairs Medical Center and the University of Minnesota, Minneapolis, Minnesota 55417, USA
    Ann Thorac Surg 83:1744-50. 2007
    ....
  23. ncbi The energetic state within hibernating myocardium is normal during dobutamine despite inhibition of ATP-dependent potassium channel opening with glibenclamide
    Edward O McFalls
    Veterans Affairs Medical Center University of Minnesota, Minneapolis, MN, USA
    Am J Physiol Heart Circ Physiol 293:H2945-51. 2007
    ....
  24. ncbi Clinical factors associated with long-term mortality following vascular surgery: outcomes from the Coronary Artery Revascularization Prophylaxis (CARP) Trial
    Edward O McFalls
    Division of Cardiology, VA Medical Center, Minneapolis, MN 55417, USA
    J Vasc Surg 46:694-700. 2007
    ..Using the nonrandomized cohort from the Coronary Artery Revascularization Prophylaxis (CARP) Trial, we analyzed the predictors of outcome based on the presenting vascular problem and prevalence of comorbid conditions and cardiac risks...
  25. ncbi Glucose uptake and glycogen levels are increased in pig heart after repetitive ischemia
    Edward O McFalls
    Cardiology Dept, 111C, Veterans Affairs Medical Center, 1 Veterans Drive, Minneapolis, MN 55417, USA
    Am J Physiol Heart Circ Physiol 282:H205-11. 2002
    ....
  26. ncbi Mitochondrial adaptations within chronically ischemic swine myocardium
    Edward O McFalls
    Experimental Cardiology, Thoraxcenter, Cardiovascular Research School COEUR, Erasmus MC, Rotterdam, The Netherlands
    J Mol Cell Cardiol 41:980-8. 2006
    ..Uncoupling protein 2 expression is enhanced in the mitochondria, providing a potential mechanism for these favorable mitochondrial adaptations...
  27. ncbi Coronary-artery revascularization before elective major vascular surgery
    Edward O McFalls
    Minneapolis Veterans Affairs Medical Center, Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis 55417, USA
    N Engl J Med 351:2795-804. 2004
    ..The benefit of coronary-artery revascularization before elective major vascular surgery is unclear...
  28. pmc Variation of mortality after coronary artery bypass surgery in relation to hour, day and month of the procedure
    Ann Coumbe
    Division of Cardiology, Veterans Administration Medical Center, One Veterans Drive, Minneapolis, Minnesota 55417, USA
    BMC Cardiovasc Disord 11:63. 2011
    ..Since these challenges are also encountered during coronary artery bypass graft (CABG) surgery that is performed after regular work hours, we assessed whether hour and day of procedure influenced mortality after CABG...
  29. doi CON: Preoperative coronary revascularization in high-risk patients undergoing vascular surgery
    Santiago Garcia
    Division of Cardiology, VA Medical Center, University of Minnesota, Minneapolis, MN, USA
    Anesth Analg 106:764-6. 2008
  30. doi Predictors and outcomes of a perioperative myocardial infarction following elective vascular surgery in patients with documented coronary artery disease: results of the CARP trial
    Edward O McFalls
    Division of Cardiology 111C, VA Medical Center, 1 Veterans Drive, Minneapolis, MN 55417, USA
    Eur Heart J 29:394-401. 2008
    ....
  31. doi Utility of N-acetylcysteine to prevent acute kidney injury after cardiac surgery: a randomized controlled trial
    A Selcuk Adabag
    Division of Cardiology, Veterans Affairs Medical Center, University of Minnesota, Minneapolis, MN 55417, USA
    Am Heart J 155:1143-9. 2008
    ..gov identifier NCT00211653)...