Research Topics
| Susan McElroySummaryAffiliation: University of Cincinnati Country: USA Publications
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Publications
Comorbidity of bipolar and eating disorders: distinct or related disorders with shared dysregulations?Susan L McElroy
Psychopharmacology Research Program, University of Cincinnati College of Medicine, P O Box 670559, 231 Bethesda Avenue, Cincinnati, OH 45267 0559, USA
J Affect Disord 86:107-27. 2005..The co-occurrence of bipolar and eating disorders, though of major clinical and public health importance, remains relatively unexamined...- Atomoxetine in the treatment of binge-eating disorder: a randomized placebo-controlled trialSusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
J Clin Psychiatry 68:390-8. 2007..Binge-eating disorder (BED) is associated with obesity. Atomoxetine is a highly selective norepinephrine reuptake inhibitor associated with weight loss. The purpose of this study was to evaluate atomoxetine in the treatment of BED... - Topiramate for the treatment of binge eating disorder associated with obesity: a placebo-controlled studySusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
Biol Psychiatry 61:1039-48. 2007..The current investigation evaluated the safety and efficacy of topiramate in a multicenter, placebo-controlled trial... - Open-label aripiprazole in the treatment of acute bipolar depression: a prospective pilot trialSusan L McElroy
Psychopharmacology Research Program, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States
J Affect Disord 101:275-81. 2007..Increasing evidence indicates that some second-generation antipsychotics are efficacious in bipolar depression, but there are few data on this illness for the novel agent aripiprazole... - Zonisamide in the treatment of binge eating disorder with obesity: a randomized controlled trialSusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
J Clin Psychiatry 67:1897-906. 2006..Binge eating disorder (BED) is associated with obesity. Zonisamide is a novel antiepileptic drug associated with weight loss. The purpose of this study was to evaluate zonisa-mide in the treatment of BED associated with obesity... - Citalopram in the treatment of binge-eating disorder: a placebo-controlled trialSusan L McElroy
Division of Psychopharmacology Research and Eating Disorders, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Clin Psychiatry 64:807-13. 2003..Citalopram is a highly selective serotonin reuptake inhibitor antidepressant. The purpose of this study was to assess the efficacy and safety of citalopram in the treatment of binge-eating disorder... - Comorbidity of eating disorders with bipolar disorder and treatment implicationsSusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
Bipolar Disord 8:686-95. 2006..To review the scientific evidence examining the comorbidity among eating disorders and bipolar disorder (BD)... - Zonisamide in the treatment of binge-eating disorder: an open-label, prospective trialSusan L McElroy
Division of Clinical Neuroscience, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
J Clin Psychiatry 65:50-6. 2004..It commonly co-occurs with obesity. Zonisamide is a novel antiepileptic drug associated with weight loss. The purpose of this study was to preliminarily assess zonisamide in the treatment of binge-eating disorder... - A 52-week, open-label continuation study of lamotrigine in the treatment of bipolar depressionSusan L McElroy
Psychopharmacology Research Program, University of Cincinnati College of Medicine, 231 Bethesda Avenue, Cincinnati, OH 45267 0559, USA
J Clin Psychiatry 65:204-10. 2004..Lamotrigine has demonstrated efficacy for the acute treatment of depression in bipolar I patients in a placebo-controlled, monotherapy study. We describe the results of a 52-week, open-label continuation of that trial... - Antidepressants and suicidal behavior in bipolar disorderSusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Bipolar Disord 8:596-617. 2006.... - Open-label adjunctive zonisamide in the treatment of bipolar disorders: a prospective trialSusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, PO Box 670559, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
J Clin Psychiatry 66:617-24. 2005..The response of 62 outpatients with DSM-IV bipolar disorders to open-label adjunctive zonisamide was evaluated in a prospective 8-week acute trial, followed by a 48-week continuation trial, conducted from June 2001 through May 2002... - Are mood disorders and obesity related? A review for the mental health professionalSusan L McElroy
Psychopharmacology Research and Eating Disorders and Obesity Research and Treatment Programs, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Clin Psychiatry 65:634-51, quiz 730. 2004..We reviewed evidence regarding a possible relationship between mood disorders and obesity to better inform mental health professionals about their overlap... - Topiramate in the long-term treatment of binge-eating disorder associated with obesitySusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Clin Psychiatry 65:1463-9. 2004..This study assessed the long-term effectiveness and tolerability of topiramate in binge-eating disorder (BED) with obesity... - A 24-week, randomized, controlled trial of adjunctive sibutramine versus topiramate in the treatment of weight gain in overweight or obese patients with bipolar disordersSusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Bipolar Disord 9:426-34. 2007..The objective of this study was to compare sibutramine and topiramate as adjunctive treatments for psychotropic-associated weight gain in overweight or obese outpatients with BD... - Diagnosing and treating comorbid (complicated) bipolar disorderSusan L McElroy
Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267, USA
J Clin Psychiatry 65:35-44. 2004.... - Olanzapine in the treatment of pathological gambling: a negative randomized placebo-controlled trialSusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Clin Psychiatry 69:433-40. 2008..Olanzapine is a second-generation antipsychotic with mood-stabilizing properties and antagonistic activity at several dopamine receptors. The purpose of this study was to evaluate olanzapine in the treatment of pathological gambling... - Relationship of open acute mania treatment to blinded maintenance outcome in bipolar I disorderSusan L McElroy
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
J Affect Disord 107:127-33. 2008..No published studies have statistically evaluated the relationship between the outcomes in maintenance treatment and the principal acute agent... - Topiramate in the treatment of binge eating disorder associated with obesity: a randomized, placebo-controlled trialSusan L McElroy
Division of Psychopharmacology Research, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
Am J Psychiatry 160:255-61. 2003..Binge eating disorder is associated with obesity. Topiramate is an antiepileptic agent associated with weight loss. The objective of this study was to evaluate topiramate in the treatment of binge eating disorder associated with obesity... - Quetiapine for the continuation treatment of bipolar depression: naturalistic prospective case series from the Stanley Bipolar Treatment NetworkTrisha Suppes
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9121, USA
Int Clin Psychopharmacol 22:376-81. 2007..No between-group differences in improvement were found. Adjunctive quetiapine may be useful as continuation treatment in bipolar populations with both pure depressive and cycling symptoms. Further controlled studies are warranted... - Mixed hypomania in 908 patients with bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network: a sex-specific phenomenonTrisha Suppes
Bipolar Disorder Research Program, Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas 75390 9121, USA
Arch Gen Psychiatry 62:1089-96. 2005..The prevalence of depressive symptoms co-occurring with hypomanic symptoms has not been quantified. Whether there is a greater likelihood for women to experience mixed symptoms has not been resolved... - Analyses of treatment-emergent mania with olanzapine/fluoxetine combination in the treatment of bipolar depressionPaul E Keck
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
J Clin Psychiatry 66:611-6. 2005..These subanalyses compare treatment-emergent mania rates in bipolar I depressed patients treated with olanzapine, placebo, or olanzapine/fluoxetine combination... - Maintenance efficacy of divalproex in the prevention of bipolar depressionLaszlo Gyulai
Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
Neuropsychopharmacology 28:1374-82. 2003.... - Lamotrigine in the treatment of binge-eating disorder with obesity: a randomized, placebo-controlled monotherapy trialAnna I Guerdjikova
Department of Psychiatry, University of Cincinnati College of Medicine, Lindner Center of HOPE, Mason, Ohio 45040, USA
Int Clin Psychopharmacol 24:150-8. 2009..As a result of an exceptionally high placebo response, it is likely that for efficacy measures except for body weight and metabolic indices, the study was incapable of detecting potentially clinically important drug-placebo difference... - Venlafaxine treatment of binge-eating disorder associated with obesity: a series of 35 patientsShishuka Malhotra
Department of Psychiatry, University of Cincinnati Medical Center, Ohio 45267-0559, USA
J Clin Psychiatry 63:802-6. 2002..No patients discontinued the drug. CONCLUSION: Venlafaxine may be an effective treatment for binge-eating disorder associated with overweight or obesity. Controlled studies of venlafaxine in binge-eating disorder appear warranted... - Subsyndromal depressive symptoms are associated with functional impairment in patients with bipolar disorder: results of a large, multisite studyLori L Altshuler
Department of Psychiatry, VA Greater Los Angeles Healthcare System, West Los Angeles Healthcare Center, CA, USA
J Clin Psychiatry 67:1551-60. 2006..Research examining this relationship in persons with bipolar disorder is rare. This study sought to evaluate the association between subsyndromal depressive symptoms and role functioning in subjects with bipolar disorder... - The comorbidity of bipolar and anxiety disorders: prevalence, psychobiology, and treatment issuesMarlene P Freeman
University of Cincinnati College of Medicine, Biological Psychiatry Program, Department of Psychiatry, P O Box 670559, 231 Bethesda Avenue, Cincinnati, OH 45267 0559, USA
J Affect Disord 68:1-23. 2002..Although symptoms of anxiety as well as anxiety disorders commonly occur in patients with bipolar disorder, the pathophysiologic, theoretical, and clinical significance of their co-occurrence has not been well studied... - Advances in the pharmacologic treatment of bipolar depressionPaul E Keck
Division of Psychopharmacology Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267-0559, USA
Biol Psychiatry 53:671-9. 2003.... - Binge eating disorder: a stable syndromeHarrison G Pope
Department of Psychiatry, Harvard Medical School and McLean Hospital, Belmont, MA 02478, USA
Am J Psychiatry 163:2181-3. 2006..This study assessed the stability of binge eating disorder in a community sample... - Divalproex in the treatment of impulsive aggression: efficacy in cluster B personality disordersEric Hollander
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
Neuropsychopharmacology 28:1186-97. 2003.... - Correlates of treatment-emergent mania associated with antidepressant treatment in bipolar depressionMark A Frye
Department of Psychiatry, Mayo Mood Clinic and Research Program, Mayo Clinic, 200 First St, S W, Rochester, MN 55901, USA
Am J Psychiatry 166:164-72. 2009..This study examined the correlates associated with treatment-emergent mania in patients receiving adjunctive antidepressant treatment for bipolar depression... - Correlates of overweight and obesity in 644 patients with bipolar disorderSusan L McElroy
Stanley Foundation Bipolar Treatment Outcome Network, Department of Psychiatry, University of Cincinnati College of Medicine, Ohio 45267-0559, USA
J Clin Psychiatry 63:207-13. 2002.... - Relationship of mania symptomatology to maintenance treatment response with divalproex, lithium, or placeboCharles L Bowden
Department of Psychiatry, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA
Neuropsychopharmacology 30:1932-9. 2005..Dysphoric mania appeared to predispose patients to more side effects when treated with either divalproex or lithium during maintenance therapy... - Impact of antidepressant continuation after acute positive or partial treatment response for bipolar depression: a blinded, randomized studyLori L Altshuler
Department of Psychiatry, Veterans Affairs Greater Los Angeles Healthcare System, West Los Angeles Healthcare Center, Los Angeles, CA, USA
J Clin Psychiatry 70:450-7. 2009..To assess long-term outcome in bipolar disorder, subjects were prospectively followed after receiving acute treatment for bipolar depression... - Psychiatric and metabolic characteristics of childhood versus adult-onset obesity in patients seeking weight managementAnna I Guerdjikova
Psychopharmacology Program, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0559, USA
Eat Behav 8:266-76. 2007..Early recognition and attention to eating and mood dysregulation, including, but not limited to binge eating disorder and bulimia nervosa, in some persons, might help reduce their lifetime risk for obesity... - Pharmacologic treatment considerations in co-occurring bipolar and anxiety disordersPaul E Keck
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267 0559, USA
J Clin Psychiatry 67:8-15. 2006..Anxiety disorders are among the most commonly co-occurring psychiatric syndromes with bipolar disorder. The presence of co-occurring anxiety disorders has important prognostic and treatment implications... - Psychopathology in children of bipolar parentsManpreet K Singh
Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
J Affect Disord 102:131-6. 2007..Few studies have examined the psychopathological profiles of child offspring of bipolar parents. Such investigations are useful as a first step to identifying potential prodromal manifestations of bipolar disorder... - Double-blind, randomized, placebo-controlled trials of ethyl-eicosapentanoate in the treatment of bipolar depression and rapid cycling bipolar disorderPaul E Keck
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine and the Mental Health Care Line, Cincinnati, Ohio 45267 0559, USA
Biol Psychiatry 60:1020-2. 2006..The results of pilot trials suggest that omega-3 fatty acids may have efficacy in the treatment of mood symptoms in bipolar disorder... - Lithium augmentation of topiramate for bipolar disorder with comorbid binge eating disorder and obesityRenu Kotwal
Department of Psychiatry, Psychopharmacology Research Program, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Hum Psychopharmacol 21:425-31. 2006..To evaluate the effectiveness of lithium augmentation of topiramate on mood symptoms, binge eating behavior, and body weight in obese bipolar patients with binge eating disorder (BED) seeking weight management... - Characterizing impulsivity in maniaStephen M Strakowski
Division of Bipolar Disorders Research, Universtiy of Cincinnati College of Medicine, Cincinnati, OH, USA
Bipolar Disord 11:41-51. 2009.... - High-dose escitalopram in the treatment of binge-eating disorder with obesity: a placebo-controlled monotherapy trialAnna I Guerdjikova
Division of Psychopharmacology Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
Hum Psychopharmacol 23:1-11. 2008..The purpose of this study was to evaluate the efficacy and safety of high-dose escitalopram in the treatment of binge-eating disorder (BED) associated with obesity... - Binge eating disorder pharmacotherapy clinical trails--who is left out?Anna I Guerdjikova
Department of Psychiatry, Lindner Center of HOPE, Mason, OH 45267 0559, USA
Eur Eat Disord Rev 17:101-8. 2009..This report examined the characteristics of subjects interested in binge eating disorder (BED) pharmacotherapy trails who were ineligible for participation... - A placebo-controlled, randomized trial of fluoxetine in the treatment of binge-eating disorderLesley M Arnold
Women s Health Research Program, Department of Psychiatry, University of Cincinnati Medical Center, Cincinnati, Ohio, USA
J Clin Psychiatry 63:1028-33. 2002..The purpose of this study was to assess the efficacy and safety of fluoxetine in the treatment of binge-eating disorder... - Redefining mood stabilizationPaul E Keck
Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
J Affect Disord 73:163-9. 2003..No available agent meets the criteria for a comprehensive mood-stabilizer, although lithium comes the closest... - Bipolar disorder, obesity, and pharmacotherapy-associated weight gainPaul E Keck
Division of Clinical Neuroscience, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Clin Psychiatry 64:1426-35. 2003..This risk may be due to factors associated with the illness itself and/or with medications used to treat bipolar disorder... - Bipolar disorders: special diagnostic and treatment considerations in womenSusan L McElroy
Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
CNS Spectr 9:5-18. 2004..Further studies are needed on gestational timing and exposure to mood-stabilizing agents, especially newer agents recently approved or currently being considered for the treatment of bipolar disorder... - Psychosis in bipolar disorder: phenomenology and impact on morbidity and course of illnessPaul E Keck
Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267-0559, USA
Compr Psychiatry 44:263-9. 2003..The lack of observable prognostic impact may have been, in part, due to the relatively high morbidity and poor functional outcome of a substantial portion of the total cohort... - Carbamazepine and valproate in the maintenance treatment of bipolar disorderPaul E Keck
Department of Psychiatry, University of Cincinnati College of Medicine, Ohio 45267 0559, USA
J Clin Psychiatry 63:13-7. 2002..We reviewed the available data from randomized clinical trials of these agents in bipolar disorder to assess their efficacy and tolerability in the maintenance phase of illness management... - Severity of bipolarity in hospitalized manic adolescents with history of stimulant or antidepressant treatmentCesar A Soutullo
University of Cincinnati, Department of Psychiatry, Biological Psychiatry and Psychotic and Bipolar Disorders Research Programs, PO Box 670559, 231 Bethesda Avenue, Cincinnati, OH 45267 0559, USA
J Affect Disord 70:323-7. 2002..Childhood bipolarity (BP) and ADHD frequently co-occur, these children often receive stimulants... - Clinical pharmacodynamics and pharmacokinetics of antimanic and mood-stabilizing medicationsPaul E Keck
Department of Psychiatry, University of Cincinnati College of Medicine, Ohio 45267 0559, USA
J Clin Psychiatry 63:3-11. 2002..We reviewed the clinical pharmacodynamics and pharmacokinetics of these agents to provide a summary of these properties relevant to clinical practice... - New approaches in managing bipolar depressionPaul E Keck
Program Psychopharmacology Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
J Clin Psychiatry 64:13-8. 2003.... - Medical management of obesity associated with mental disordersShishuka Malhotra
Biological Psychiatry Program, University of Cincinnati College of Medicine, Ohio 45267-0559, USA
J Clin Psychiatry 63:24-32. 2002..In this review, we aim to improve understanding of the relationship between obesity and mental illness and provide practical clinical guidelines for the management of obesity associated with mental disorders... - Response of recurrent binge eating and weight gain to topiramate in patients with binge eating disorder after bariatric surgeryAnna I Guerdjikova
Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Obes Surg 15:273-7. 2005..The effectiveness of topiramate was evaluated in the treatment of recurrent binge eating and weight gain in patients with binge eating disorder (BED) and obesity who had undergone initially successful bariatric surgery... - Psychiatric and legal features of 113 men convicted of sexual offensesNeal W Dunsieth
Center for the Study of Criminal Behavior, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267-0559, USA
J Clin Psychiatry 65:293-300. 2004..On the basis of our findings, we assert that sex offenders should be carefully evaluated for the presence of mental illness and that sex offender management programs should have a capacity for psychiatric treatment... - Divalproex in the treatment of bipolar disorderPaul E Keck
Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, PO Box 670559, Cincinnati, OH 45267, USA
Psychopharmacol Bull 37:67-73. 2003..The results of randomized, controlled trials of valproate in the treatment of bipolar disorder are reviewed along with their implications for clinical practice... - Aripiprazole: a partial dopamine D2 receptor agonist antipsychoticPaul E Keck
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine and General Clinical Research Center, Mental Health Service Line, Cincinnati Veterans Affairs Medical Center, Cincinnati, Ohio, USA
Expert Opin Investig Drugs 12:655-62. 2003..In addition, aripiprazole was not associated with significant weight gain or QTc prolongation in both acute and long-term treatment trials... - Emotional eating and emotional eating alternatives in subjects undergoing bariatric surgeryAnna I Guerdjikova
Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
Obes Surg 17:1091-6. 2007..The purpose of this study was to characterize emotional eating and its alternatives in obese patients undergoing bariatric surgery... - Awareness of metabolic concerns and perceived impact of pharmacotherapy in patients with bipolar disorder: a survey of 500 US psychiatristsTrisha Suppes
Department of Psychiatry, Bipolar Disorder Research Program, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9121, USA
Psychopharmacol Bull 40:22-37; quiz 38-40. 2007.... - Are bipolar mood symptoms affected by the phase of the menstrual cycle?Geetha Shivakumar
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9086, USA
J Womens Health (Larchmt) 17:473-8. 2008..We sought to examine the relationship between bipolar disorder and menstrual cycle-related mood changes. To our knowledge, this is one of the largest samples in the literature addressing this issue... - Binge-eating disorder as a distinct familial phenotype in obese individualsJames I Hudson
Department of Psychiatry, Harvard Medical School and McLean Hospital, Belmont, Mass 02478, USA
Arch Gen Psychiatry 63:313-9. 2006..However, it remains unclear whether BED represents an etiologically distinct behavioral phenotype of obesity or simply a nonspecific eating pattern sometimes seen in obese individuals... - Familiality of temperament in bipolar disorder: support for a genetic spectrumLynn Evans
Department of Psychiatry, UCSD, School of Medicine, University of California, 9500 Gilman Drive, La Jolla, CA 92093-0603, USA
J Affect Disord 85:153-68. 2005..Nevertheless, both of these scales may be useful quantitative traits for genetic mapping studies... - Impulsive aggression with irritability and responsive to divalproex: a pediatric bipolar spectrum disorder phenotype?Drew H Barzman
Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
J Affect Disord 88:279-85. 2005..In addition, we examined whether the symptomatology of this group was consistent with a pediatric divalproex-responsive bipolar spectrum disorder... - Impact of bipolar disorder on a U.S. community sampleJoseph R Calabrese
Department of Psychiatry, Case Western Reserve University, University Hospitals of Cleveland, Cleveland, Ohio 44106, USA
J Clin Psychiatry 64:425-32. 2003..Bipolar symptoms have been associated with significant functional impairment. We conducted a study to determine the psychosocial impact of bipolar disorder in a U.S. community sample... - Reproductive function and risk for PCOS in women treated for bipolar disorderNatalie L Rasgon
Department of Psychiatry, Stanford School of Medicine, Palo Alto, CA, USA
Bipolar Disord 7:246-59. 2005..This study examined the reproductive function and prevalence of polycystic ovary syndrome (PCOS) in women with bipolar disorder taking antimanic medications... - Screening for bipolar disorder in the communityRobert M A Hirschfeld
Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, Galveston, 77555 188, USA
J Clin Psychiatry 64:53-9. 2003..Our goal was to estimate the rate of positive screens for bipolar I and bipolar II disorders in the general population of the United States... - A placebo-controlled evaluation of adjunctive modafinil in the treatment of bipolar depressionMark A Frye
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, UCLA, Los Angeles, USA
Am J Psychiatry 164:1242-9. 2007..This study was conducted to evaluate the efficacy and safety of adjunctive modafinil in bipolar depression, which is often characterized by excessive sleepiness and fatigue... - Gender differences in prevalence, risk, and clinical correlates of alcoholism comorbidity in bipolar disorderMark A Frye
Department of Psychiatry and Biobehavioral Sciences, UCLA Bipolar Research Program, University of California Los Angeles School of Medicine, 300 UCLA Medical Plaza, Suite 1544, Los Angeles, CA 90095, USA
Am J Psychiatry 160:883-9. 2003..This study examined gender-specific relationships between alcoholism and bipolar illness, which have previously received little systematic study... - Comparison of rapid-cycling and non-rapid-cycling bipolar disorder based on prospective mood ratings in 539 outpatientsRalph W Kupka
Altrecht Institute for Mental Health Care, Tolsteegsingel 2A, 3582 AC Utrecht, Netherlands
Am J Psychiatry 162:1273-80. 2005..To detect risk factors for rapid cycling in bipolar disorder, the authors compared characteristics of rapid-cycling and non-rapid-cycling patients both from a categorical and a dimensional perspective... - Preliminary observations on the effectiveness of levetiracetam in the open adjunctive treatment of refractory bipolar disorderRobert M Post
Biological Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
J Clin Psychiatry 66:370-4. 2005..Given the effectiveness of a range of other anticonvulsants in bipolar disorder, we sought to evaluate levetiracetam in patients with treatment-resistant illness... - Risk of switch in mood polarity to hypomania or mania in patients with bipolar depression during acute and continuation trials of venlafaxine, sertraline, and bupropion as adjuncts to mood stabilizersGabriele S Leverich
Biological Psychiatry Branch, National Institutes of Mental Health, Bldg 10 Room 3S239, 10 Center Drive, MSC 1272, Bethesda, MD 20892 1272, USA
Am J Psychiatry 163:232-9. 2006..The authors examined the comparative risks of switches in mood polarity into hypomania or mania during acute and continuation trials of adjunctive antidepressant treatment of bipolar depression... - Lower switch rate in depressed patients with bipolar II than bipolar I disorder treated adjunctively with second-generation antidepressantsLori L Altshuler
Dept of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, 300 UCLA Medical Plaza, Suite 1544, Box 957057, Los Angeles, CA 90095 7057
Am J Psychiatry 163:313-5. 2006..The authors compared the switch rate into hypomania/mania in depressed patients treated with second-generation antidepressants who had either bipolar I or bipolar II disorder... - A 7-week, randomized, double-blind trial of olanzapine/fluoxetine combination versus lamotrigine in the treatment of bipolar I depressionEileen B Brown
Lilly Research Laboratories, Indianapolis, IN, USA
J Clin Psychiatry 67:1025-33. 2006..Determine the efficacy and tolerability of olanzapine/fluoxetine combination (OFC) for treatment of acute bipolar I depression compared with lamotrigine... - Correlates of 1-year prospective outcome in bipolar disorder: results from the Stanley Foundation Bipolar NetworkWillem A Nolen
Altrecht Institute for Mental Health Care, Utrecht, The Netherlands
Am J Psychiatry 161:1447-54. 2004..The purpose of the study was to examine potential correlates of outcome in patients treated for bipolar disorder... - Pharmacological approaches in the treatment of binge eating disorderJose C Appolinario
Obesity and Eating Disorders Group Institute of Psychiatry, Federal University of Rio de Janeiro and Institute of Endocrinology and Diabetes of Rio de Janeiro, Brazil
Curr Drug Targets 5:301-7. 2004..Special issues concerning current pharmacological trials and future research directions in this area are also discussed... - An overview of recent findings of the Stanley Foundation Bipolar Network (Part I)Robert M Post
Stanley Foundation Bipolar Network and Biological Psychiatry Branch, NIMH, NIH, DHHS, Bethesda, MD 20892 1272, USA
Bipolar Disord 5:310-9. 2003..Selected recent findings of the Stanley Foundation Bipolar Network are briefly reviewed and their clinical implications discussed... - Olanzapine versus placebo in acute mania: treatment responses in subgroupsRoss J Baldessarini
International Consortium for Bipolar Disorder Research, Department of Psychiatry and Neuroscience Program, Harvard Medical School, Boston, MA, USA
J Clin Psychopharmacol 23:370-6. 2003..5-1.7, all P < 0.01). These well-powered comparisons of subgroups of interest indicate broad efficacy of olanzapine in the treatment of acute mania... - Problem gambling in bipolar disorder: results from the Canadian Community Health SurveyRoger S McIntyre
Department of Psychiatry, University of Toronto, Toronto, ON, Canada
J Affect Disord 102:27-34. 2007..This investigation was undertaken to explore the prevalence and associated features of problem gambling amongst individuals with bipolar I disorder... - Pharmacologic treatment of binge eating disorderWilliam P Carter
Biological Psychiatry Laboratory, McLean Hospital, Belmont, MA 02478, USA
Int J Eat Disord 34:S74-88. 2003..To review the findings from pharmacologic trials of binge eating disorder (BED) and to provide guidelines for pharmacologic treatment... - Morbidity in 258 bipolar outpatients followed for 1 year with daily prospective ratings on the NIMH life chart methodRobert M Post
Stanley Foundation Bipolar Network and Biological Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 12723, USA
J Clin Psychiatry 64:680-90; quiz 738-9. 2003..The detailed course and pattern of illness emerging despite comprehensive treatment with mood stabilizers and adjunctive agents have previously not been well delineated... - Factors associated with suicide attempts in 648 patients with bipolar disorder in the Stanley Foundation Bipolar NetworkGabriele S Leverich
Stanley Foundation Bipolar Treatment Outcome Network, Department of Health and Human Services, National Institutes of Health, National Institute of Mental Health, Biological Psychiatry Branch, Bethesda, MD 20892 1272, USA
J Clin Psychiatry 64:506-15. 2003..We investigated demographic and course-of-illness variables to better understand the incidence and potential clinical correlates of serious suicide attempts in 648 outpatients with bipolar disorder... - Substance use disorders and overweight/obesity in bipolar I disorder: preliminary evidence for competing addictionsRoger S McIntyre
Department of Psychiatry, University of Toronto, Ontario, Canada
J Clin Psychiatry 68:1352-7. 2007..This investigation was undertaken to explore the relationship between alcohol/illicit drug dependence and overweight/obesity in individuals with bipolar I disorder...
Research Grants
- Bipolar II Depression: Lithium, SSRI or the CombinationSusan McElroy; Fiscal Year: 2007..We also hypothesize that the frequency of side effects will be significantly less in patients on SSRI monotherapy. Thus, secondary aims include assessment of patient satisfaction, which may affect compliance in the clinical setting. ..
- Bipolar II Depression: Lithium, SSRI or the CombinationSusan L McElroy; Fiscal Year: 2010..We also hypothesize that the frequency of side effects will be significantly less in patients on SSRI monotherapy. Thus, secondary aims include assessment of patient satisfaction, which may affect compliance in the clinical setting. ..