MARY C MCELLISTREM

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc Simplified protocol for pulsed-field gel electrophoresis analysis of Streptococcus pneumoniae
    M C McEllistrem
    Public Health Infectious Diseases Laboratory, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA
    J Clin Microbiol 38:351-3. 2000
  2. ncbi request reprint A hospital outbreak of Clostridium difficile disease associated with isolates carrying binary toxin genes
    M Catherine McEllistrem
    University of Pittsburgh School of Medicine, Pittsburgh, PA 15213 2582, USA
    Clin Infect Dis 40:265-72. 2005
  3. ncbi request reprint Acute otitis media due to penicillin-nonsusceptible Streptococcus pneumoniae before and after the introduction of the pneumococcal conjugate vaccine
    M Catherine McEllistrem
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213 2582, USA
    Clin Infect Dis 40:1738-44. 2005
  4. ncbi request reprint Recurrent invasive pneumococcal disease in individuals with human immunodeficiency virus infection
    M Catherine McEllistrem
    Infectious Diseases Epidemiology Research Unit, University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, Pennsylvania 15213 2582, USA
    J Infect Dis 185:1364-8. 2002
  5. ncbi request reprint Distribution of penicillin-nonsusceptible pneumococcal clones in the Baltimore metropolitan area and variables associated with drug resistance
    M Catherine McEllistrem
    Infectious Diseases Epidemiology Research Unit, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, 15213, USA
    Clin Infect Dis 34:704-7. 2002
  6. pmc Erythromycin-nonsusceptible Streptococcus pneumoniae in children, 1999-2001
    M Catherine McEllistrem
    University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, Pennsylvania 15213 2582, USA
    Emerg Infect Dis 11:969-72. 2005
  7. pmc Clonal groups of penicillin-nonsusceptible Streptococcus pneumoniae in Baltimore, Maryland: a population-based, molecular epidemiologic study
    M C McEllistrem
    Infectious Diseases Epidemiology Research Unit, University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Clin Microbiol 38:4367-72. 2000
  8. pmc Serotype 14 variants of the France 9V(-3) clone from Baltimore, Maryland, can be differentiated by the cpsB gene
    M Catherine McEllistrem
    Infectious Diseases Epidemiology Research Unit, Division of Infectious Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15229, USA
    J Clin Microbiol 42:250-6. 2004
  9. ncbi request reprint Epidemiology of acute otitis media caused by Streptococcus pneumoniae before and after licensure of the 7-valent pneumococcal protein conjugate vaccine
    M Catherine McEllistrem
    Division of Infectious Diseases, University of Pittsburgh School of Medicine and Graduate School of Public Health, Pittsburgh, Pennsylvania 15213 2582, USA
    J Infect Dis 188:1679-84. 2003
  10. doi request reprint Marked increase in biofilm-derived rough pneumococcal variants and rifampin-resistant strains not due to hex gene mutations
    M Catherine McEllistrem
    University of Pittsburgh, Department of Medicine, Pittsburgh, Pennsylvania, USA
    Microb Drug Resist 15:85-90. 2009

Research Grants

  1. PREVENTION OF PNEUMOCOCCAL DISEASE IN HIV INFECTION
    MARY MCELLISTREM; Fiscal Year: 2004

Collaborators

Detail Information

Publications21

  1. pmc Simplified protocol for pulsed-field gel electrophoresis analysis of Streptococcus pneumoniae
    M C McEllistrem
    Public Health Infectious Diseases Laboratory, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA
    J Clin Microbiol 38:351-3. 2000
    ..pneumoniae. The ES solution may have caused cell lysis by activating N-acetylmuramyl-L-alanine amidase, the pneumococcal autolysin...
  2. ncbi request reprint A hospital outbreak of Clostridium difficile disease associated with isolates carrying binary toxin genes
    M Catherine McEllistrem
    University of Pittsburgh School of Medicine, Pittsburgh, PA 15213 2582, USA
    Clin Infect Dis 40:265-72. 2005
    ..The binary toxin genes cdt and cdtB have been detected in approximately 5% of Clostridium difficile strains. Severe C. difficile disease (CDD) may be associated with strains that carry the binary toxin genes...
  3. ncbi request reprint Acute otitis media due to penicillin-nonsusceptible Streptococcus pneumoniae before and after the introduction of the pneumococcal conjugate vaccine
    M Catherine McEllistrem
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213 2582, USA
    Clin Infect Dis 40:1738-44. 2005
    ..The impact of the 7-valent pneumococcal conjugate vaccine (PCV7 [Prevnar]) on penicillin-nonsusceptible Streptococcus pneumoniae (PNSP) recovered from children with acute otitis media (AOM) is unclear...
  4. ncbi request reprint Recurrent invasive pneumococcal disease in individuals with human immunodeficiency virus infection
    M Catherine McEllistrem
    Infectious Diseases Epidemiology Research Unit, University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, Pennsylvania 15213 2582, USA
    J Infect Dis 185:1364-8. 2002
    ..Although a substantial proportion of recurrent pneumococcal infections was potentially preventable by vaccine, creating an effective vaccine may be challenging for this population...
  5. ncbi request reprint Distribution of penicillin-nonsusceptible pneumococcal clones in the Baltimore metropolitan area and variables associated with drug resistance
    M Catherine McEllistrem
    Infectious Diseases Epidemiology Research Unit, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, 15213, USA
    Clin Infect Dis 34:704-7. 2002
    ....
  6. pmc Erythromycin-nonsusceptible Streptococcus pneumoniae in children, 1999-2001
    M Catherine McEllistrem
    University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, Pennsylvania 15213 2582, USA
    Emerg Infect Dis 11:969-72. 2005
    ..The decline in infection rates was likely due to the pneumococcal 7-valent conjugate vaccine...
  7. pmc Clonal groups of penicillin-nonsusceptible Streptococcus pneumoniae in Baltimore, Maryland: a population-based, molecular epidemiologic study
    M C McEllistrem
    Infectious Diseases Epidemiology Research Unit, University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Clin Microbiol 38:4367-72. 2000
    ..The classification of PNSP strains into clonal groups is essential for future population-based epidemiologic studies of PNSP...
  8. pmc Serotype 14 variants of the France 9V(-3) clone from Baltimore, Maryland, can be differentiated by the cpsB gene
    M Catherine McEllistrem
    Infectious Diseases Epidemiology Research Unit, Division of Infectious Diseases, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15229, USA
    J Clin Microbiol 42:250-6. 2004
    ..Although the correlation between serotype and the cpsB sequence was high, the overall diversity of the cpsB gene within a serotype likely will limit the role of this gene in a sequence-based serotyping method...
  9. ncbi request reprint Epidemiology of acute otitis media caused by Streptococcus pneumoniae before and after licensure of the 7-valent pneumococcal protein conjugate vaccine
    M Catherine McEllistrem
    Division of Infectious Diseases, University of Pittsburgh School of Medicine and Graduate School of Public Health, Pittsburgh, Pennsylvania 15213 2582, USA
    J Infect Dis 188:1679-84. 2003
    ..In 1999 and 2001, 30.8% (4/13) and 26.1% (6/23) of the nonvaccine serogroups were implicated in capsular switching, respectively. Continued surveillance will be of great importance as the distribution of the PNC7 vaccine increases...
  10. doi request reprint Marked increase in biofilm-derived rough pneumococcal variants and rifampin-resistant strains not due to hex gene mutations
    M Catherine McEllistrem
    University of Pittsburgh, Department of Medicine, Pittsburgh, Pennsylvania, USA
    Microb Drug Resist 15:85-90. 2009
    ..Taken together, these data suggest that mutations in the hex genes and modulation of hexA activity are unlikely to account for the generation of biofilm-derived rough variants...
  11. pmc Correlating epidemiologic trends with the genotypes causing meningococcal disease, Maryland
    M Catherine McEllistrem
    University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, Pennsylvania, USA
    Emerg Infect Dis 10:451-6. 2004
    ..The nonepidemic age-specific increases in serogroup C meningococcal infection in Maryland were clonal in nature and the changes in serogroup Y incidence were associated with a shift in the genotypes of strains causing invasive disease...
  12. pmc Characterization of in vitro biofilm-associated pneumococcal phase variants of a clinically relevant serotype 3 clone
    M Catherine McEllistrem
    Division of Infectious Diseases, University of Pittsburgh School of Medicine, PA 15213 2582, USA
    J Clin Microbiol 45:97-101. 2007
    ..These in vitro phase variation data, which underscore the plasticity of the pneumococcus, need to be confirmed with in vivo analyses of the middle ear mucosa during otitis media...
  13. ncbi request reprint Detection of very high-level penicillin-resistant variants of the Tennessee (23 F)-4 clone via single and serial transformations with four serotype 19 A international pneumococcal clones
    M Catherine McEllistrem
    University of Pittsburgh School of Medicine, Pittsburgh, PA 15213 2582, USA
    Microb Drug Resist 11:271-8. 2005
    ..Recombination within the MLST housekeeping genes was commonly detected in the transformants that had acquired penicillin resistance...
  14. doi request reprint Alternative strategies for adult pneumococcal polysaccharide vaccination: a cost-effectiveness analysis
    Kenneth J Smith
    Section of Decision Sciences and Clinical Systems Modeling, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States
    Vaccine 26:1420-31. 2008
    ..PPV at ages 50/65 may be clinically and, depending on cost-effectiveness criterion used, economically favored over present vaccination recommendations...
  15. pmc Locus-specific mutational events in a multilocus variable-number tandem repeat analysis of Escherichia coli O157:H7
    Anna C Noller
    Infectious Diseases Epidemiology Research Unit, University of Pittsburgh Graduate School of Public Health and School of Medicine, 521 Parran Hall, 130 DeSoto St, Pittsburgh, PA 15261, USA
    J Clin Microbiol 44:374-7. 2006
    ..The remaining four loci had no slippage events detected. The mutation rates were locus specific and may impact the interpretation of MLVA data for epidemiologic investigations...
  16. pmc Multilocus variable-number tandem repeat analysis distinguishes outbreak and sporadic Escherichia coli O157:H7 isolates
    Anna C Noller
    Infectious Diseases Epidemiology Research Unit, University of Pittsburgh Graduate School of Public Health and School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    J Clin Microbiol 41:5389-97. 2003
    ..In addition to being a simple and validated method for E. coli O157:H7 outbreak detection, MLVA appears to have a sensitivity equal to that of PFGE and a specificity superior to that of PFGE...
  17. ncbi request reprint Emergence of a novel penicillin-nonsusceptible, invasive serotype 35B clone of Streptococcus pneumoniae within the United States
    Bernard Beall
    Division of Bacterial and Mycotic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 186:118-22. 2002
    ..The mosaic pbp2b and divergent ddl sequences were suggestive of interspecies recombination at the ddl-pbp2b chromosomal region...
  18. ncbi request reprint Geographic, demographic, and seasonal differences in penicillin-resistant Streptococcus pneumoniae in Baltimore
    Bernadette A Albanese
    Department of International Health, Johns Hopkins University School of Hygiene and Public Health, Baltimore, MD, USA
    Clin Infect Dis 34:15-21. 2002
    ..The incidence of PRSP is increasing in Baltimore, and the seasonality of PRSP suggests that recent antibiotic use, which is more common in winter months, may rapidly affect the prevalence of resistant pneumococcal infections...
  19. pmc Clonal distribution of invasive pneumococcal isolates from children and selected adults in the United States prior to 7-valent conjugate vaccine introduction
    Robert E Gertz
    Division of Bacterial and Mycotic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Clin Microbiol 41:4194-216. 2003
    ..In this work, we established the basic genetic structure within individual serotypes prior to PC7V use. The resultant database will be useful for detecting potential selective effects of this vaccine in postvaccine surveillance...
  20. pmc Pre- and postvaccination clonal compositions of invasive pneumococcal serotypes for isolates collected in the United States in 1999, 2001, and 2002
    Bernard Beall
    Repsiratory Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, Mailstop C02, Atlanta, Georgia 30333, USA
    J Clin Microbiol 44:999-1017. 2006
    ..Continued genotypic surveillance is warranted, since certain clones not targeted by PCV7 are expanding, and their emergence as significant pathogens could occur with maintained vaccine pressure...
  21. pmc Genotyping primers for fully automated multilocus variable-number tandem repeat analysis of Escherichia coli O157:H7
    Anna C Noller
    J Clin Microbiol 42:3908. 2004

Research Grants1

  1. PREVENTION OF PNEUMOCOCCAL DISEASE IN HIV INFECTION
    MARY MCELLISTREM; Fiscal Year: 2004
    ..All patients who exhibit a greater that 3-fold transient rise in HIV-1 RNA levels 2 and 4 weeks postimmunization will be evaluated by Fisher's Exact and McNemar's Tests. ..