Research Topics
| C R McDonaldSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Subcortical and cerebellar atrophy in mesial temporal lobe epilepsy revealed by automatic segmentationCarrie R McDonald
Department of Psychiatry, University of California, San Diego, United States
Epilepsy Res 79:130-8. 2008..To determine the validity and utility of using automated subcortical segmentation to identify atrophy of the hippocampus and other subcortical and cerebellar structures in patients with mesial temporal lobe epilepsy (MTLE)...
Regional rates of neocortical atrophy from normal aging to early Alzheimer diseaseC R McDonald
Department of Psychiatry, University of California, San Diego, CA, USA
Neurology 73:457-65. 2009..To evaluate the spatial pattern and regional rates of neocortical atrophy from normal aging to early Alzheimer disease (AD)...
Diffusion tensor imaging correlates of memory and language impairments in temporal lobe epilepsyC R McDonald
Multimodal Imaging Laboratory, Suite C101, 8950 Villa La Jolla Drive, La Jolla, CA 92037, USA
Neurology 71:1869-76. 2008..To investigate the relationship between white matter tract integrity and language and memory performances in patients with temporal lobe epilepsy (TLE)...
Multimodal imaging of repetition priming: Using fMRI, MEG, and intracranial EEG to reveal spatiotemporal profiles of word processingCarrie R McDonald
Department of Psychiatry, University of California, San Diego, CA, USA
Neuroimage 53:707-17. 2010....
Changes in fiber tract integrity and visual fields after anterior temporal lobectomyC R McDonald
Department of Psychiatry, Multimodal Imaging Laboratory, University of California San Diego, 8950 Villa La Jolla Drive, La Jolla, CA 92037, USA
Neurology 75:1631-8. 2010....
Regional neocortical thinning in mesial temporal lobe epilepsyCarrie R McDonald
Department of Psychiatry, and Multimodal Imaging Laboratory, University of California, San Diego, CA 92093 0841, USA
Epilepsia 49:794-803. 2008..To determine the nature and extent of regional cortical thinning in patients with mesial temporal lobe epilepsy (MTLE)...
The use of neuroimaging to study behavior in patients with epilepsyCarrie R McDonald
Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA
Epilepsy Behav 12:600-11. 2008..In addition, advances in multimodal imaging are discussed along with their potential application to the presurgical evaluation of patients with seizure disorders...
A componential analysis of proverb interpretation in patients with frontal lobe epilepsy and temporal lobe epilepsy: relationships with disease-related factorsCarrie R McDonald
Veterans Administration San Diego Healthcare System, USA
Clin Neuropsychol 22:480-96. 2008..Overall, FLE patients exhibit greater impairment than TLE patients in interpreting proverbs. However, the nature and disease-specific correlates of impaired performances in proverb interpretation differ between the groups...
Episodic memory in patients with focal frontal lobe lesionsCarrie R McDonald
Department of Clinical and Health Psychology, University of Florida, FL, USA
Cortex 42:1080-92. 2006..Furthermore, both patient groups show a lack of directed forgetting when familiarity-based processes guide performance...
The relationship of regional frontal hypometabolism to executive function: a resting fluorodeoxyglucose PET study of patients with epilepsy and healthy controlsCarrie R McDonald
Multimodal Imaging Laboratory, University of California, San Diego, La Jolla, CA, USA
Epilepsy Behav 9:58-67. 2006....
Discriminating patients with frontal-lobe epilepsy and temporal-lobe epilepsy: utility of a multilevel design fluency testCarrie R McDonald
Veterans Administration San Diego Healthcare System, La Jolla, CA 92611, and Department of Psychiatry, University of California, San Diego, CA, USA
Neuropsychology 19:806-13. 2005....
Is impairment in set-shifting specific to frontal-lobe dysfunction? Evidence from patients with frontal-lobe or temporal-lobe epilepsyCarrie R McDonald
Psychology Service 116B Delis Lab, Veterans Administration San Diego Healthcare System, 3350 La Jolla Village Drive, La Jolla, CA 92611, USA
J Int Neuropsychol Soc 11:477-81. 2005..These results suggest that patients with FLE can be reliably distinguished from those with TLE and control subjects on set-shifting as measured by the DKEFS TMT...
Response inhibition and set shifting in patients with frontal lobe epilepsy or temporal lobe epilepsyCarrie R McDonald
Veterans Administration San Diego Healthcare System, and Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA
Epilepsy Behav 7:438-46. 2005..In addition, side of the seizure focus and seizure frequency may contribute to executive dysfunction in patients with epilepsy...
Semantic priming in patients with right frontal lobe lesionsCarrie R McDonald
Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida, USA
J Int Neuropsychol Soc 11:132-43. 2005..These results support a role for the right frontal lobe in semantic priming and suggest possible specialization within the right prefrontal cortex for the processing of lexical-semantic information...
Attentional inhibition in patients with focal frontal lobe lesionsCarrie R McDonald
Department of Clinical and Health Psychology, University of Florida, USA
J Clin Exp Neuropsychol 27:485-503. 2005....
Neuropsychological change following gamma knife surgery in patients with left temporal lobe epilepsy: a review of three casesCarrie R McDonald
Department of Psychiatry, University of California, San Diego, CA, USA
Epilepsy Behav 5:949-57. 2004....
Distributed source modeling of language with magnetoencephalography: application to patients with intractable epilepsyCarrie R McDonald
Department of Psychiatry, University of California, San Diego, California, USA
Epilepsia 50:2256-66. 2009....
Relationship between regional atrophy rates and cognitive decline in mild cognitive impairmentCarrie R McDonald
Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA
Neurobiol Aging 33:242-53. 2012..MRI measures of regional atrophy can provide valuable information for understanding the neural basis of cognitive impairment in MCI...
Role of frontotemporal fiber tract integrity in task-switching performance of healthy controls and patients with temporal lobe epilepsyN Erkut Kucukboyaci
Department of Psychiatry, University of California San Diego, La Jolla, CA 92037, USA
J Int Neuropsychol Soc 18:57-67. 2012..These findings suggest a breakdown of typical structure-function relationships in TLE that may reflect aberrant developmental or degenerative processes...
Side matters: diffusion tensor imaging tractography in left and right temporal lobe epilepsyM E Ahmadi
Multimodal Imaging Laboratory, University of California, San Diego, CA 92103 8756, USA
AJNR Am J Neuroradiol 30:1740-7. 2009..Noninvasive imaging plays a pivotal role in lateralization of the seizure focus in presurgical patients with temporal lobe epilepsy (TLE). Our goal was to evaluate the utility of diffusion tensor imaging (DTI) tractography in TLE...
Verbal encoding deficits in a patient with a left retrosplenial lesionC R McDonald
Department of Clinical and Health Psychology, University of Florida Brain Institute, Gainesville, Florida 32610 0165, USA
Neurocase 7:407-17. 2001..These results imply that the retrosplenial region plays a role in the verbal encoding of information, which contributes to the profound verbal memory impairment reported in previous case studies of patients with retrosplenial damage...
Automated white-matter tractography using a probabilistic diffusion tensor atlas: Application to temporal lobe epilepsyDonald J Hagler
Multimodal Imaging Laboratory, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
Hum Brain Mapp 30:1535-47. 2009..However, the between-group effect sizes using the atlas-derived fibers were generally as large or larger than those obtained with manually selected fiber tracks...
White matter tracts associated with set-shifting in healthy agingMichele E Perry
Department of Cognitive Science, University of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093, USA
Neuropsychologia 47:2835-42. 2009..Automated tractography methods can enhance our understanding of the fiber systems involved in performance of specific cognitive tasks and of the functional consequences of age-related changes in those systems...
Cognitive discrepancies versus APOE genotype as predictors of cognitive decline in normal-functioning elderly individuals: a longitudinal studyEric M Fine
Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, USA
Am J Geriatr Psychiatry 16:366-74. 2008....
Research Grants
- Cortical Dynamics of Episodic Memory Processing in Tempora Lobe EpilepsyCarrie McDonald; Fiscal Year: 2007..This information may facilitate surgical planning and reduce the potential for postoperative cognitive decline. ..
- Multimodal Imaging of Language in the Preoperative Evaluation of EpilepsyCarrie R McDonald; Fiscal Year: 2010..The information gained from this investigation may facilitate surgical planning and reduce the potential for postoperative language decline in patients with epilepsy. ..
